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Table 3 Distribution of samples according to BP and kidney function [counts and (percentages)]

From: Pathogen-based target attainment of optimized continuous infusion dosing regimens of piperacillin-tazobactam and meropenem in surgical ICU patients: a prospective single center observational study

 

Piperacillin-tazobactam

Meropenem

0.25 mg/L

8 mg/L

16 mg/L

BP unknown

2 mg/L

BP unknown

(N = 10)

(N = 808)

(N = 257)

(N = 817)

(N = 631)

(N = 297)

ARC

4 (40.0)

168 (20.8)

59 (23.0)

149 (18.2)

126 (20.3)

52 (17.5)

Stable kidney function

4 (40.0)

335 (41.5)

115 (44.8)

354 (43.3)

274 (44.1)

139 (46.8)

AKI I

2 (20.0)

110 (13.6)

32 (12.5)

90 (11.0)

63 (10.1)

34 (11.5)

AKI II

0 (0.0)

70 (8.6)

25 (9.7)

93 (11.4)

41 (6.6)

29 (9.8)

AKI III

0 (0.0)

33 (4.1)

1 (0.4)

29 (3.6)

17 (2.7)

7 (2.4)

RRT

0 (0.0)

92 (11.4)

25 (9.7)

102 (12.5)

100 (16.1)

36 (12.1)

  1. BP Break point, ARC Augmented renal clearance, AKI Acute kidney injury, RRT Renal replacement therapy