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Table 1 Main differences between acute heart failure and cardiogenic shock

From: Microcirculatory dysfunction in cardiogenic shock

 

Acute heart failure

Cardiogenic shock

Onset

• Days (e.g., acute decompensated heart failure)

• Hours (e.g., acute pulmonary oedema)

• Hours

Blood pressure

• SBP > 90 mmHg

• Life-threatening hypotension with SBP < 90 mmHg or MAP < 60 mmHg

• BP may be initially preserved by compensatory vasoconstriction

Cardiac index (CI)

• CI > 2.2 L/min/m2 usually

• Low CI ≤ 2.2 L/min/m2

Hypoperfusion and organ dysfunction

• Sometimes

• Always

Main clinical presentations

• Wet-warm (70%)

• Wet-cold (20%)

• Wet-cold (65%)

• Dry-cold (30%)

Need for vasopressors/inotropes to achieve and maintain a target SBP > 90 mmHg or MAP ≥ 65 mmHg

• No

• Yes

Arterial lactate

• < 2 mmol/L usually

•  ≥ 2 mmol/L

pH level

• Normal pH usually

• Metabolic acidosis

Consider temporary MCS

• Rarely (e.g., “protected PCI” with Impella)

• Sometimes

  1. This main clinical presentation is based on bedside evaluation and categorization by clinical signs of congestion (‘wet’ vs. ‘dry’ if present vs. absent) and hypoperfusion (‘cold’ vs. ‘warm’ if present vs. absent)
  2. CI cardiac index, MAP mean arterial pressure, MCS mechanical circulatory support, SBP systolic blood pressure