Antibiotic stewardship in the ICU: time to shift into overdrive

Annals of Intensive Care

Table 3 Proposed duration of antimicrobial therapy according to infection site

Infection site	Proposed duration (days)	References
Uncomplicated bloodstream infection	7–8	[204]
Uncomplicated catheter-related infection	7, unless Staphylococcus aureus and Candida spp.	[205]
Acute exacerbation of COPD	5	[206]
Community-acquired pneumonia	5–7	[59]
HAP and VAP	7–8, including Pseudomonas aeruginosa	[42, 57, 145]
Intra-abdominal infections	5–7, with optimal source control	[192]
Post-operative peritonitis	5–15, with optimal source control	[192, 193]
Severe community-acquired UTI		[207]
Female	7
Male	14
Cellulitis	7	[208]
Necrotizing fasciitis	14–21, with full surgical debridement	[208]
Neutropenia	3, if apyrexia and no documentation in a stable patient	[209]

COPD chronic obstructive pulmonary disease, HAP healthcare-associated pneumonia, UTI urinary tract infection, VAP ventilator-associated pneumonia