Outcome | Patients (n, %) | Univariate logistic analysis | Multivariate logistic analysis | |||
---|---|---|---|---|---|---|
OR (95% CI) | P | *OR (95% CI) | P | |||
30-day mortality | Entire cohort | 126/307 (41.0) | 1.104 (0.698–1.747) | 0.671 | 1.124 (0.707–1.786) | 0.622 |
Immunocompromised | 65/117 (55.6) | 0.396 (0.176–0.892) | 0.025 | 0.404 (0.170–0.962) | 0.041 | |
Immunocompetent | 61/190 (32.1) | 1.597 (0.864–2.592) | 0.135 | 1.349 (0.712–2.554) | 0.359 | |
APACHE II score ≥ 15 | 92/193 (47.7) | 0.471 (0.256–0.866) | 0.015 | 0.494 (0.256–0.951) | 0.035 | |
APACHE II score < 15 | 34/114 (29.8) | 2.956 (1.290–6.770) | 0.010 | 2.357 (0.820–6.677) | 0.111 | |
30-day clinical response | Entire cohort | 167/307 (54.4) | 0.999 (0.636–1.570) | 0.996 | 0.987 (0.626–1.557) | 0.956 |
Immunocompromised | 52/117 (44.4) | 2.523 (1.121–5.674) | 0.025 | 2.601 (1.088–6.218) | 0.032 | |
Immunocompetent | 115/190 (60.5) | 0.709 (0.395–1.271) | 0.248 | 0.833 (0.453–1.530) | 0.555 | |
APACHE II score ≥ 15 | 95/193 (49.2) | 2.128 (1.153–3.926) | 0.016 | 2.096 (1.082–4.058) | 0.028 | |
APACHE II score < 15 | 72/114 (63.2) | 0.440 (0.201–0.965) | 0.041 | 0.584 (0.212–1.608) | 0.298 | |
30-day microbiology eradiction ǂ | Entire cohort | 131/272 (48.2) | 1.049 (0.649–1.693) | 0.846 | 1.035 (0.640–1.677) | 0.888 |
Immunocompromised | 38/106 (35.8) | 2.625 (1.049–6.569) | 0.039 | 2.788 (1.027–7.567) | 0.044 | |
Immunocompetent | 93/166 (56.0) | 0.827 (0.448–1.528) | 0.544 | 0.955 (0.504–1.810) | 0.887 | |
APACHE II score ≥ 15 | 79/175 (45.1) | 2.199 (1.150–2.407) | 0.017 | 2.256 (1.123–4.534) | 0.022 | |
APACHE II score < 15 | 52/97 (53.6) | 0.388 (0.168–0.896) | 0.027 | 0.478 (0.164–1.397) | 0.177 |