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Annals of Intensive Care
Fig. 1 | Annals of Intensive Care

Fig. 1

From: Rationale and evidence for the use of new beta-lactam/beta-lactamase inhibitor combinations and cefiderocol in critically ill patients

Fig. 1

Administration scheme and dosing adjustments of new β-lactam/β-lactamase inhibitor combinations and cefiderocol in critically ill patients. See the text and Table 4 for references. CFL: cefiderocol; CFL: cefiderocol; C-TZ: ceftolozane–tazobactam; CAZ-AVI: ceftazidime–avibactam; MER-VAB: meropenem–vaborbactam; IMI-REL: imipenem–relebactam; CrCl: creatinine clearance; MIC: minimal inhibitory concentration; AKI: acute kidney injury; TDM: therapeutic drug monitoring; IHD: intermittent haemodialysis; CRRT: continuous renal replacement therapy; LD: loading dose

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