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Table 2 Spectrum of new beta-lactams with or without beta-lactamase inhibitors

From: The place of new antibiotics for Gram-negative bacterial infections in intensive care: report of a consensus conference

  1. KPC = Klebsiella pneumoniae carbapenemases; MβL = metallo-beta-lactamases; NDM = New-Delhi MβL; OXA-48 = oxacillinase-48; XDR = extensively drug-resistant [113]
  2. Green boxes: mainly susceptible species
  3. Red boxes: mainly resistant species
  4. Orange box: despite being highly susceptible in vitro, clinical efficacy remains uncertain, with excess mortality in a subgroup of the credible trial [11]