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Annals of Intensive Care

Table 4 Univariate and multivariable logistic regression analysis for 360-day mortality (7322 patients included)

From: Long-term survival after intensive care for COVID-19: a nationwide cohort study of more than 8000 patients

 

Univariate

Multivariablea

OR (95% CI)

P-value

OR (95% CI)

P-value

Sex

 Women

Reference

 

Reference

 

 Men

1.21 (1.08–1.35)

0.0010

1.33 (1.17–1.52)

0.0000

Age, per year

1.08 (1.07–1.09)

0.0000

1.08 (1.07–1.09)

0.0000

Comorbidity

 Cardiac disease

2.64 (2.32–3)

0.0000

1.38 (1.19–1.6)

0.0000

 COPD/Asthma

1.6 (1.41–1.82)

0.0000

1.51 (1.31–1.74)

0.0000

 Diabetes

1.42 (1.27–1.59)

0.0000

1.17 (1.02–1.33)

0.0219

 Morbid obesityb

0.71 (0.59–0.86)

0.0005

1.17 (0.93–1.45)

0.1734

 Hypertension

1.63 (1.47–1.8)

0.0000

0.87 (0.77–0.98)

0.0274

 Immune deficiency

1.9 (1.6–2.26)

0.0000

1.71 (1.4–2.09)

0.0000

 Chronic liver disease

3.48 (2.12–5.8)

0.0000

2.01 (1.13–3.6)

0.0176

 Chronic kidney disease

2.19 (1.8–2.66)

0.0000

1.14 (0.91–1.42)

0.2529

 Neuromuscular disease

1.81 (1.2–2.71)

0.0041

2.06 (1.25–3.39)

0.0044

 Malignancyc

2.99 (2.2–4.07)

0.0000

1.52 (1.08–2.15)

0.0157

 SAPS3, per 1 unit increased

1.07 (1.06–1.07)

0.0000

1.06 (1.05–1.07)

0.0000

Admission periode

 Wave 1

Reference

 

Reference

 

 Wave 2

1.34 (1.18–1.52)

0.0000

0.85 (0.74–0.99)

0.0000

 Wave 3

0.98 (0.87–1.11)

0.8013

0.84 (0.74–0.97)

0.0142

  1. OR odds ratio, CI confidence interval, COPD chronic obstructive pulmonary disease, SAPS simplified acute physiology score
  2. a7322 patients included in the univariate and multivariable models
  3. bDefined as BMI > 40 kg/m2
  4. cMalignancy is defined as neoplasia spread beyond regional lymph nodes
  5. dRecalculated after excluding age and comorbidities
  6. eWave 1, 200306-200830; Wave 2, 200901-210131; Wave 3, 210201-211130; Wave 4, 211201-220812
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