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Annals of Intensive Care
Fig. 2 | Annals of Intensive Care

Fig. 2

From: Trends in ICU mortality and underlying risk over three decades among mechanically ventilated patients. A group level analysis of cohorts from infection prevention studies

Fig. 2

Scatter plot and linear regression of ICU mortality [mortality censured at day 21 or less] incidence versus year of study publication for observational groups and control and interventions groups from studies of non-decontamination and decontamination interventions. The linear regression line in each plot, derived using the observational groups, increased non-significantly versus year of study publication (slope is + 1.2 percentage points per decade; 95% confidence interval − 1.9 to + 4.3; p = 0.64) and serves as a benchmark for all plots [symbols; filled triangle = non-concurrent control groups; filled square = groups receiving PPAP; open circle = all other groups; NCC groups appear as observational groups]. PPAP is protocolized parenteral antibiotic prophylaxis. The equivalent plot for late mortality is shown as Additional file 1: Fig S3 and plots with the originating studies indicated in Additional file 1: Figs. S2, S3. Note the y-axis is a logit scale

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