Table 2 Clinical endpoints
HFNO (N = 229) | Ventilation (N = 499) | p | |
|---|---|---|---|
Primary endpoint | |||
ICU mortality, n/N (%) | 52/229 (22.7) | 172/483 (35.6) | 0.001 |
Secondary endpoints | |||
28–day mortality, n/N (%) | 50/229 (21.8) | 159/499 (31.9) | 0.007 |
90–day mortality, n/N (%) | 57/229 (24.9) | 178/483 (36.9) | 0.002 |
Hospital mortality, n/N (%) | 56/229 (24.5) | 178/483 (36.9) | 0.001 |
ICU length of stay, days (median [IQR])* | (225/229) 8 [4–19] | (462/483) 13 [7–26] | < 0.001 |
ICU length of stay in survivors, days (median [IQR])* | (168/229) 7 [4–13] | (285/483) 11 [7–30] | < 0.001 |
Hospital length of stay, days (median [IQR])* | (224/229) 14 [10–25] | (462/483) 19 [13–31] | < 0.001 |
Hospital length of stay in survivors, days (median [IQR])* | (167/229) 14 [10–28] | (284/483) 23 [14–45] | < 0.001 |
Need for intubation and ventilation, N (%) | 105 (45.8) | ||
Respiratory support free days (median [IQR]) | 22 [0–25] | 9 [0–22] | < 0.001 |