From: Angiopoietin-2 is associated with capillary leak and predicts complications after cardiac surgery
 | All patients (N = 393) | CABG (N = 100) | AV (N = 63) | MV (N = 52) | Multivalve (N = 32) | Aorta (N = 86) | LVAD (N = 21) | Others (N = 39) |
---|---|---|---|---|---|---|---|---|
General characteristics | ||||||||
Age (mean ± SD) | 63 ± 14 | 67 ± 11 | 66 ± 12 | 60 ± 10 | 69 ± 12 | 63 ± 14 | 57 ± 15 | 51 ± 17 |
Male (%) | 295 (75%) | 92 (92%) | 46 (73%) | 38 (73.1%) | 21 (65.6%) | 64 (74.4%) | 16 (76.2%) | 18 (46.2%) |
BMI (mean ± SD) | 27 ± 5 | 28 ± 5 | 28 ± 4 | 25 ± 4 | 25 ± 4 | 27 ± 6 | 25 ± 3 | 26 ± 5 |
30-day mortality (%) | 26 (7%) | 1 (1%) | 5 (7.9%) | 3 (5.8%) | 3 (9.4%) | 6 (7%) | 7 (33%) | 1 (2.6%) |
Length of ICU stay (days, median ± IQR) | 3 (1–5) | 2 (1–3) | 2 (1–4) | 3 (1–4) | 3 (2–5) | 3 (2–6) | 9 (6–10) | 2 (1–4) |
Days until extubation (median ± IQR) | 0 (0–1) | 0 (0–1) | 0 (0–1) | 0 (0–1) | 0 (0–1) | 0 (0–1) | 3 (1–8) | 0 (0–1) |
EuroScore (mean ± SD) | 6 ± 4 | 5 ± 3 | 6 ± 4 | 4 ± 4 | 8 ± 4 | 7 ± 5 | 12 ± 3 | 6 ± 5 |
7-day Follow-Up After ICU Discharge (%) | 192 (49%) | 47 (47%) | 32 (51%) | 27 (52%) | 14 (44%) | 50 (58%) | 11 (52%) | 11 (28%) |
Surgical characteristics | ||||||||
Cardiopulmonary Bypass Time, min (median ± IQR) | 135 (105–165) | 105 (75–135) | 135 (105–165) | 135 (105–210) | 150 (135–210) | 165 (135–210) | 105 (105–158) | 75 (75–135) |
Deep Hypothemic Cardiac Arrest (%) | 47 (12%) | 0 | 1 (2%) | 0 | 0 | 45 (52%) | 0 | 1 (3%) |
Selective Antegrade Cerebral Perfusion (%) | 45 (11%) | 0 | 0 | 0 | 0 | 43 (50%) | 0 | 0 |
Intraoperative CPR (%) | 5 (1%) | 0 | 2 (3%) | 1 (2%) | 0 | 2 (2%) | 0 | 0 |
Postoperative ECMO (%) | 15 (4%) | 2 (2%) | 3 (5%) | 5 (10%) | 1 (3%) | 3 (4%) | 0 | 1 (3%) |
Postoperative IABP (%) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Postoperative Impella (%) | 1 (0.2%) | 0 | 0 | 1 (2%) | 0 | 0 | 0 | 0 |
Postoperative RVAD (%) | 4 (1%) | 0 | 0 | 0 | 0 | 0 | 4 (19%) | 0 |
Complications | ||||||||
Sepsis (%) | 8 (2%) | 0 | 2 (3%) | 1 (2%) | 2 (6%) | 1 (1%) | 1 (5%) | 1 (3%) |
ARDS (%) | 2 (1%) | 0 | 1 (2%) | 1 (2%) | 0 | 0 | 0 | 0 |
AKI, overall (%) | 158 (40%) | 33 (33%) | 21 (33%) | 20 (39%) | 17 (53%) | 37 (43%) | 17 (81%) | 13 (33%) |
 KDIGO I (%) | 129 (33%) | 29 (29%) | 18 (29%) | 16 (31%) | 16 (50%) | 24 (28%) | 14 (67%) | 12 (31%) |
 KDIGO II (%) | 19 (5%) | 3 (3%) | 1 (2%) | 3 (6%) | 1 (3%) | 10 (12%) | 1 (5%) | 0 |
 KDIGO III (%) | 10 (3%) | 1 (1%) | 2 (3%) | 1 (2%) | 0 | 3 (3%) | 2 (10%) | 1 (3%) |
 RRT (%) | 14 (4%) | 2 (2%) | 1 (2%) | 0 | 2 (6%) | 4 (5%) | 3 (14%) | 2 (5%) |
Intraoperative fluid balance (mL, mean ± SD) | 3234 ± 1074 | 2761 ± 1007 | 3225 ± 1321 | 3253 ± 926 | 3059 ± 1231 | 3331 ± 1319 | 4365 ± 1502 | 3100 ± 1666 |
Weight gain at the end of surgery (kg, mean ± SD) | 4.7 ± 1.8 | 3.6 ± 1.9 | 4.1 ± 1.3 | 4.2 ± 1.5 | 5.1 ± 3.7 | 4.7 ± 2 | 5.2 ± 3.1 | 3.6 ± 2.8 |
ALF (%) | 3 (1%) | 0 | 1 (2%) | 1 (2%) | 1 (3%) | 0 | 0 | 0 |
Low-Cardiac Output Syndrome (%) | 43 (11%) | 6 (6%) | 5 (8%) | 7 (14%) | 5 (15%) | 6 (7%) | 12 (57%) | 2 (6%) |
Reoperation within first 7Â days (%) | 53 (14%) | 8 (8%) | 8 (13%) | 4 (8%) | 3 (9%) | 18 (21%) | 9 (43%) | 3 (8%) |