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Table 2 Effects of volume expansion on hemodynamic parameters in fluid responders and non-responders stratified by the median value of P0.1

From: Inspiratory effort impacts the accuracy of pulse pressure variations for fluid responsiveness prediction in mechanically ventilated patients with spontaneous breathing activity: a prospective cohort study

 

P0.1 < 1.5 cmH2O

P0.1 ≥ 1.5 cmH2O

 

responders (n = 22)

non-responders (n = 68)

responders (n = 31)

non-responders (n = 68)

Baseline

After fluids

Baseline

After fluids

Baseline

After fluids

Baseline

After fluids

MAP, mmHg

77.6 (11.0)

83.2 (15.0)

89.0 (13.7)$

91.3 (14.1)&

79.4 (13.5)

84.5 (12.5)

88.9 (13.5)$

91.0 (13.2)&

CVP, mmHg

8.1 (3.5)

7.7 (4.1)

8.9 (3.3)

10.6 (4.5)&#

8.1 (4.3)

8.8 (4.6)

10.2 (4.3)$

11.3 (4.6)&

PPV, %

15.5 (5.4)

13.3 (6.5)

7.1 (3.8)$

6.4 (2.3)&

11.9 (6.3)

11.6 (4.5)

8.0 (3.9)$

8.8 (5.0)&

SVV, %

15.6 (7.4)

12.2 (6.1)

6.4 (2.3)$

6.2 (3.5)&

11.9 (7.0)

11.3 (5.0)

8.5 (5.3)$

8.4 (4.8)&

Cardiac output, L/min

4.9 (1.0)

6.1 (1.4)*

6.3 (1.5)$

6.4 (1.6)

5.8 (1.3)

7.2 (2.1)*

6.93 (1.96)$

7.0 (2.21)

Cardiac index, L/min/m2

2.8 (0.5)

3.5 (0.8)*

3.8 (0.9)$

3.8 (0.9)

3.3 (0.7)

4.2 (1.0)*

3.96 (0.97)$

4.0 (1.0)

  1. *p < 0.05: After Fluids versus Baseline (responders)
  2. #p < 0.05: After Fluids versus Baseline (non-responders)
  3. $p < 0.05: non-responders versus responders (Baseline)
  4. &p < 0.05: non-responders versus responders (After Fluids)
  5. MAP Mean arterial pressure, CVP Central venous pressure, PPV Pulse pressure variation, SVV Stroke volume variation