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Annals of Intensive Care

Table 3 Effects of volume expansion on hemodynamic parameters in fluid responders and non-responders stratified by the median value of ΔPocc

From: Inspiratory effort impacts the accuracy of pulse pressure variations for fluid responsiveness prediction in mechanically ventilated patients with spontaneous breathing activity: a prospective cohort study

 

ΔPocc < − 9.8 cmH2O

ΔPocc ≥ − 9.8 cmH2O

 

responders (n = 32)

non-responders (n = 61)

responders (n = 21)

non-responders (n = 75)

Baseline

After fluids

Baseline

After fluids

Baseline

After fluids

Baseline

After fluids

MAP, mmHg

80.0 (12.3)

84.6 (13.0)

86.4 (11.8)$

88.2 (12.6)

76.7 (12.6)

83.0 (14.40)

91.0 (14.6)$

93.5 (14.1)&

CVP, mmHg

8.0 (3.5)

8.7 (4.2)

10.1 (3.8)$

11.3 (4.6)&

8.3 (4.7)

7.9 (4.7)

9.2 (3.9)

10.7 (4.5)&#

PPV, %

13.7 (6.6)

12.0 (4.6)

7.6 (3.5)$

8.4 (4.7)&

12.6 (5.5)

12.7 (6.6)

7.4 (4.1)$

6.9 (3.2)&

SVV, %

14.1 (7.8)

11.4 (5.6)

8.3 (4.6)$

8.3 (4.6)&

12.0 (6.4)

11.9 (5.2)

6.7 (5.1)$

6.5 (3.9)&

Cardiac output, L/min

5.6 (1.3)

7.1 (2.1)*

6.9 (1.8)$

7.0 (1.9)

5.2 (1.2)

6.3 (1.6)*

6.4 (1.7)$

6.5 (1.8)

Cardiac index, L/min/m2

3.1 (0.70)

4.0 (1.0)*

4.0 (0.9)$

4.0 (1.0)

3.1 (0.7)

3.77 (0.90)*

3.8 (0.9)$

3.8 (0.9)

  1. *p < 0.05: After Fluids versus Baseline (responders);
  2. #p < 0.05: After Fluids versus Baseline (non-responders);
  3. $p < 0.05: non-responders versus responders (Baseline)
  4. &p < 0.05: non-responders versus responders (After Fluids)
  5. MAP Mean arterial pressure, CVP Central venous pressure, PPV Pulse pressure variation, SVV Stroke volume variation
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