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Annals of Intensive Care

Table 4 The accuracy of pulse pressure variations to predict fluid responsiveness in patients with different degrees of inspiratory effort

From: Inspiratory effort impacts the accuracy of pulse pressure variations for fluid responsiveness prediction in mechanically ventilated patients with spontaneous breathing activity: a prospective cohort study

 

AUROC

Threshold, %

Sensitivity, %

Specificity, %

Positive predictive value, %

Negative predictive value, %

P0.1

  < 1.5 cmH2O

0.90 (0.82–0.99)*

 > 10.5

86.8 (76.5–97.1)

90.9 (72.7–100)

68.0 (55.0–89.5)

96.6 (91.2–100)

  ≥ 1.5 cmH2O

0.68 (0.57–0.79)

 > 9.5

83.9 (45.2–100)

51.5 (30.9–86.8)

44.3 (37.8–59.5)

87.9 (76.7–100)

ΔPocc

  < − 9.8 cmH2O

0.74 (0.64–0.84)

 > 9.5

90.6 (46.9–100)

54.1 (36.1–91.8)

50.9 (43.3–76.7)

90 (76.4–100)

  ≥ − 9.8 cmH2O

0.81 (0.69–0.93)#

 > 10

71.4 (47.6–90.5)

87.3 (69.0–97.2)

60.9 (41.9–84.6)

91.2 (85.3–96.8)

  1. *p = 0.0016 versus P0.1 ≥ 1.5 cmH20;
  2. #p = 0.38 versus ΔPocc < − 9.8 cmH2O
  3. AUROC Area under the receiver operating characteristic curve, P0.1 Airway occlusion pressure
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