Table 1 Characteristics of primary NIV patients
Feature | VIP2 | COVIP | p-value |
|---|---|---|---|
Entire group | |||
Number of patients | 491 | 206 | |
Age | 83.00 (81.0 to 86.0) | 83.0 (81.0 to 85.0) | 0.044 |
Female sex | 251 (51.1) | 67 (32.5) | < 0.001 |
SOFA | 4.0 (3.0 to 6.0) | 5.0 (3.0 to 7.0) | 0.117 |
CFS | 4.0 (3.0 to 6.0) | 4.0 (3.0 to 6.0) | 0.022 |
Frailty category | |||
Fit (CFS ≤ 3) | 152 (31.1) | 84 (42.9) | |
Vulnerable (CFS = 4) | 116 (23.7) | 29 (14.8) | 0.004 |
Frail (CFS ≥ 5) | 221 (45.2) | 83 (42.3) | |
LLST introduction during NIV | 181 (37.3) | 83 (40.5) | 0.486 |
30-day mortality | 179 (36.5) | 135 (65.5) | p < 0.001 |
Intubation rate | 86 (17.5) | 76 (36.9) | p < 0.001 |
NIV failure | 222 (45.3) | 157 (76.2) | p < 0.001 |
ICU length of stay | 4.0 (1.9 to 7.6) | 8.0 (4.0 to 14.8) | p < 0.001 |
Survivors | 4.1 (2.0 to 7.8) | 8.5 (5.6 to 21.2) | p < 0.001 |
Non-survivors | 4.0 (1.5 to 7.3) | 7.6 (3.1 to 13.3) | p < 0.001 |
Without LLST on NIV* | |||
Number of patients | 304 | 122 | |
Age | 83.0 (81.0 to 86.0) | 83.0 (81.0 to 84.8) | 0.087 |
Female sex | 154 (50.7) | 41 (33.6) | 0.002 |
SOFA | 4.0 (3.0 to 6.0) | 5.0 (3.0 to 7.0) | 0.022 |
CFS | 4.0 (3.0 to 5.0) | 3.0 (3.0 to 5.0) | 0.007 |
Frailty category | |||
Fit (CFS ≤ 3) | 117 (38.6) | 63 (54.8) | 0.012 |
Vulnerable (CFS = 4) | 74 (24.4) | 21 (18.3) | |
Frail (CFS ≥ 5) | 112 (37.0) | 31 (27.0) | |
30-day mortality | 71 (23.4) | 64 (52.5) | < 0.001 |
Intubation rate | 86 (28.3) | 76 (62.3) | < 0.001 |
NIV failure | 115 (37.8) | 86 (70.5) | < 0.001 |