Table 2 Summary of outcome analyses
Factor | Outcomes | |||
|---|---|---|---|---|
30-day mortality, HR (95% CI) | Intubation rate, OR (95% CI) | NIV failure, OR (95% CI) | 30-day mortality (sensitivity analysis), HR (95% CI) | |
Age | 1.04 (1.01 to 1.07) | 0.86 (0.80 to 0.92) | 1.00 (0.96 to 1.05) | 1.02 (0.96 to 1.08) |
Female sex | 0.81 (0.63 to 1.03) | 1.30 (0.86 to 1.99) | 0.90 (0.64 to 1.27) | 0.84 (0.58 to 1.22) |
SOFA | 1.08 (1.04 to 1.13) | 1.27 (1.18 to 1.37) | 1.22 (1.14 to 1.31) | 1.10 (1.03 to 1.17) |
CFS | 1.16 (1.08 to 1.24) | 0.78 (0.69 to 0.88) | 1.09 (0.98 to 1.20) | 1.11 (0.99 to 1.24) |
Study (COVIP vs. VIP2) | 2.18 (1.71 to 2.77) | 2.63 (1.74 to 3.99) | 4.21 (2.84 to 6.34) | 2.64 (1.83 to 3.80) |