Physiological effects of high-flow nasal cannula oxygen therapy after extubation: a randomized crossover study

Annals of Intensive Care

Table 1 Baseline patient characteristics

Characteristics	All patients (n = 22)
Age, years	59 ± 17
Female sex, n %	9 (41)
Body mass index, kg/mt²	32 ± 9
Charlson comorbidity index	3 ± 2
APACHE II at ICU admission	14 ± 8
SOFA (day of the study)	5 ± 3
SOFA (peak during ICU)	7 ± 3
PaO₂/FiO₂ (lowest value during MV), mmHg	136 ± 56
Length of mechanical ventilation, days	8 ± 4
Characteristics at the end of the SBT
Heart rate, bpm	90 ± 12
Systolic arterial pressure, mmHg	145 ± 23
Diastolic arterial pressure, mmHg	99 ± 16
Mean arterial pressure, mmHg	76 ± 18
Respiratory rate, bpm	22 ± 5
Tidal volume, ml	479 ± 133
P 0.1, cmH₂O	0.77 ± 0.99
PaO₂/FiO₂	242 ± 67
PaCO₂, mmHg	36 ± 5
pH	7.46 ± 0.05

Abbreviations: APACHE: Acute Physiology and Chronic Health Evaluation; SOFA: Sequential Organ Failure Assessment; ICU: intensive care unit; AHRF: acute hypoxemic respiratory failure; MV: mechanical ventilation; SBT: spontaneous breathing trial; P 0.1: airway occlusion pressure at 100 ms; PaCO₂: partial pressure of carbon dioxide. Variables are expressed as the mean ± standard deviation