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Table 2 MRI characteristics of NMOSD attacks requiring orotracheal intubation versus attacks not requiring orotracheal intubation

From: Risk factors and prognosis of orotracheal intubation in aquaporin-4-IgG neuromyelitis optica spectrum disorder attacks

 

New T2 lesion

Gadolinium enhancing lesion

OTI-attacks

Non-OTI-attacks

P-value

OTI-attacks

Non-OTI-attacks

P-value

Patients with brain MRI—gadolinium injection performed during attack

7 (87.5)

45 (69.2)

 

7 (87.5)

39 (60.0)

 

Brain location

 Medulla oblongataa

7 (87.5)

19 (34.5)

0.073

4 (50)

9 (16.3)

0.029

 Pons

1 (14.3)

5 (11.1)

0.936

1 (14.3)

2 (5.1)

0.822

 Midbrain

0 (0)

3 (6.7)

0 (0)

1 (2.6)

 Diencephalon

0 (0)

4 (8.9)

1 (14.3)

3 (7.7)

0.883

 Corpus callosum

1 (14.3)

2 (4.4)

0.954

1 (14.3)

2 (5.1)

0.963

 Hemispheric

2 (28.6)

12 (26.7)

0.986

1 (14.3)

6 (15.4)

0.936

 Optic nerve or chiasma

1 (14.3)

7 (15.6)

0.990

1 (14.3)

5 (12.8)

0.958

 None

2 (28.6)

13 (28.9)

0.972

5 (71.4)

24 (61.5)

0.907

Patients with spinal MRI—gadolinium injection performed during attack

8 (100)

52 (80.0)

 

7 (87.5)

46 (70.7)

 

Spinal cord level

 C1

6 (75)

12 (23.1)

0.329

6 (85.7)

10 (21.7)

0.354

 C2

6 (75)

15 (28.8)

0.040

6 (85.7)

11 (23.9)

0.078

 C3

6 (75)

15 (28.8)

0.043

6 (85.7)

10 (21.7)

0.080

 C4

6 (75)

11 (21.2)

0.045

5 (71.4)

7 (15.2)

0.047

 C5

5 (62.5)

12 (23.1)

0.035

5 (71.4)

4 (8.7)

0.037

 C6

4 (50)

8 (15.4)

0.594

4 (57.1)

5 (10.9)

0.041

 C7

4 (50)

10 (19.2)

0.652

3 (42.9)

4 (8.7)

0.623

 Thoracolumbar

4 (50.0)

22 (42.3)

0.874

2 (25.0)

14 (26.9)

0.877

 None

1 (12.5)

10 (19.2)

0.467

1 (14.3)

17 (36.9)

0.464

  1. Results are expressed in median (interquartile range) or N (%) unless otherwise specified
  2. OTI orotracheal intubation, MRI magnetic resonance imaging
  3. P-value is estimated with binomial generalized linear mixed model, with a random intercept for patient ID. Due to separation issues, p-value has not been estimated for some variables
  4. aMedulla oblongata T2 new lesion or gadolinium enhancement was assessed through radiological analysis of brain or spinal MRI