Table 3 Treatment and prognosis of attacks requiring orotracheal intubation versus attacks not requiring orotracheal intubation

Hospitalization duration, days

21 (7–48)

74 (55–98)

21 (7–36)

0.061

Delay from attack first symptoms to hospitalization, days

11.5 (4–21.2)

18 (7.5–32.5)

10.5 (3.8–21)

0.779

ICU hospitalization: yes

28 (38.4)

8 (100)

20 (27.4)

-

 If yes: ICU duration, days, median (P25;P75) (N attacks with ICU hospitalization)

25 (12;40) (28)

44.5 (40;57) (8)

17 (7;28) (20)

0. 094

 If yes: SAPS II, median (P25;P75) (N attacks with ICU hospitalization)

13 (6;18.25) (28)

19 (17;19) (8)

13 (6;13) (20)

0.891

 Intubation duration, days

–

27.00 [17.00, 41.50]

–

–

 Aspiration pneumonia

–

3 (37.5)

–

–

 Ventilator-associated pneumonia

–

5 (62.5)

–

–

 Tracheostomy

–

2 (37.5)

–

–

Medical treatment

 Total dose of corticosteroids (grams)

7.5 (5;10)

10 (8;10)

7 (5;10)

0.677

 Delay from first symptoms to IV corticosteroids, days

14 (7–32)

24.5 (13–58.5)

13 (6–30)

0.701

 TPE (yes or no)

35 (47.9)

8 (100)

27 (41.5)

–

 Number of TPE

6 (5–8)

7.5 (6.3–10)

6 (5–8)

0.911

 Delay from first symptoms to TPE, days

21.5 (12.5–44)

28 (16.5–82)

20 (9.3–38)

0.599

Outcomes

 Death during hospitalization

1 (1.3)

1 (12.5)

0 (0.0)

–

 EDSS 3 months after attack onset, median (IQR) (NA)

4.0 (2.5–7.0) (13)

7.0 (6.0–9.0) (0)

3.5 (2.5–6.5) (13)

0. 402

 EDSS 6 months after attack onset

3.5 (2.0–7.0) (14)

5.5 (2.5–9.0) (0)

3.5 (2.5–6.5) (14)

0.574

 EDSS 12 months after attack onset (0)

3.5 (2.0–6.5) (0)

5.0 (2.0–9.0) (0)

3.5 (2.0–6.0) (0)

0.524

 EDSS < 4, 12 months after attack

38 (52.1)

4 (50.0)

34 (52.3)

0.476

 Recurrent attack during the following year

29 (39.7)

1 (12.5)

28 (43.1)

0.624

 Patient working 12 months after attack

22 (33.8)

2 (28.5)

20 (34.5)

0.028

 Modified Rankin scale 12 months after the attack

2 [1, 3]

2 [1, 3]

2 [1, 3.5]

0.549

 Unfavorable attack recovery^a at 12 months

17 (24.3)

2 (25.0)

15 (24.2) (3)

0.468