Bedside personalized methods based on electrical impedance tomography or respiratory mechanics to set PEEP in ARDS and recruitment-to-inflation ratio: a physiologic study

Annals of Intensive Care

Table 1 Patients’ characteristics at baseline

	All patients n = 19
Demographics
Age, years	64 [54–67]
Female gender (%)	4 (21)
BMI, kg.m⁻²	30.4 [24.8–33.6]
SAPS II score at ICU admission	45 [38–51]
ARDS etiology (%)
Pulmonary	15 (79)
Extra-pulmonary	4 (21)
Mechanics and gas exchange at PEEP 5 cmH₂O
PaO₂/FiO₂, mmHg	120 [94–168]
PaCO₂, mmHg	47 [39–52]
pH	7.33 [7.29–7.39]
Ventilatory Ratio	1.97 [1.64–2.45]
Tidal volume/PBW, mL.kg⁻¹	6.1 [6.0–6.2]
Respiratory rate, min⁻¹	30 [24–29]
PEEPtot, cmH₂O	7.0 [5.5–8.0]
Plateau pressure, cmH₂O	15 [14–18]
AOP > 5 cmH₂O (%)	4 (21)
C_RS, mL.cmH₂O⁻¹	50 [40–63]
C_CW, mL.cmH₂O⁻¹	158 [131–219]
E_L/E_RS ratio	0.70 [0.61–0.79]

AOP Airway Opening Pressure, ARDS Acute Respiratory Distress Syndrome, BMI Body Mass Index, C_CW chest wall compliance, C_RS respiratory system compliance, E_L/E_RS lung elastance to respiratory system elastance ratio, FiO₂ Fraction of inspired oxygen, PaCO₂ Partial pressure of arterial carbon dioxide, PaO₂ Partial pressure of arterial oxygen, PEEPtot total Positive End-Expiratory Pressure, PLR Potential for Lung Recruitment, SAPS II Simplified Acute Physiology Score II