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Table 3 Blood transfusions and interventions required for bleeding complications within the first 48 h because information on the exact volume of blood transfused was only obtained during this time in this registry

From: Risk factors for bleeding complications in patients undergoing extracorporeal cardiopulmonary resuscitation following out-of-hospital cardiac arrest: a secondary analysis of the SAVE-J II study

 

RBCs a transfusion during the first 48 h(U)

FFP a transfusion during the first 48 h (U)

PCs b transfusion during the first 48 h (U)

Total c transfusion during the first 48 h (U)

IVR

n = 25

Surgical intervention

n = 60

Canula site bleeding (n = 234)

10 (4–18)

8 (4–16)

0 (0–10)

20 (9.5–44.5)

2 (8.0)

41 (68.3)

Retroperitoneal bleeding (n = 45)

12 (6–24)

15 (7.5–22.5)

0 (0–20)

34 (20–68)

3 (12.0)

3 (5.0)

Puncture site bleeding except ECMO cannulation site (n = 14)

8 (3.5–14)

9 (4–12)

0 (0–17.5)

24 (8.5–35.75)

2 (8.0)

2 (3.3)

Cerebral hemorrhage (n = 12)

12 (0–18)

11 (0–16.5)

0 (0–22.5)

30 (0–46)

0(0)

1 (1.9)

Upper airway bleeding (n = 19)

9 (6–14)

9.5 (1.5–14.5)

0 (0–5)

21 (8–30.5)

0(0)

1 (1.9)

Chest (n = 43)

    

12 (48.0)

6 (13.0)

Mediastinal bleeding (n = 18)

12 (4.5–24)

20 (10–28)

0 (0–50)

28 (14.5–102.5)

8 (32.0)

4 (6.7)

Hemothorax (n = 11)

18 (12–30)

10 (4–32)

20 (0–20)

40 (22–96)

3 (12.0)

2 (3.7)

Pulmonary hemorrhage (n = 14)

8 (5–14)

6 (3–17)

0 (0–0)

14 (9–28)

1 (4.0)

0 (0)

Others (n = 2)

15 (12–18)

17 (16–18)

0 (0–0)

32 (30–34)

0(0)

1 (1.9)

Abdomen (n = 55)

    

8 (32.0)

6 (11.1)

Gastrointestinal tract bleeding (n = 36)

8 (4–15.5)

10 (4–16)

0 (0–18.8)

22 (4.5–40)

0(0)

0 (0)

Liver bleeding (n = 14)

26 (14.5–38)

24 (11.5–52)

20 (0–35)

73 (29.5–136)

7 (28.0)

6 (10.0)

Splenic bleeding (n = 2)

2 (0–4)

9 (6–12)

0 (0–0)

11 (6–16)

0(0)

0 (0)

Intraperitoneal bleeding (n = 4)

12 (10–14)

12 (4–12)

20 (0–30)

46 (14–54)

2 (8.0)

0 (0)

Others (n = 9)

6 (4–14)

10 (0–13)

0(0–15)

16 (5–47)

1 (4.0)

3 (5.6)

  1. aOne unit of blood product is derived from 200 mL of whole blood. One unit of RBC and FFP are 140 and 120 mL, respectively
  2. bTen units of blood product is derived from 400 mL of whole blood. Ten units of PCs is approximately 200 mL
  3. cTotal means the sum of RBCs, FFP, and PC units
  4. Missing data: blood transfusion volume = 21
  5. ECMO, extracorporeal membrane oxygenation; RBCs, red blood cells; FFP, fresh frozen plasma; PCs, platelet concentrates; IVR, interventional radiology