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Table 2 Outcomes

From: Impact of dexamethasone in severe COVID-19-induced acute kidney injury: a multicenter cohort study

 

All patients (n = 798)

Non DXM (n = 331)

DXM (n = 467)

p value

Acute kidney injury*, n (%)

598 (75%)

282 (85%)

316 (67%)

< 0.001

 Defined using SCr, n (%)

345 (58%)

198 (70%)

147 (47%)

< 0.001

 Defined using diuresis criterion, n (%)

552 (92%)

249 (88%)

303 (96%)

0.030

 AKI Stage 1, n (%)

225 (38%)

100 (35%)

125 (40%)

0.287

 AKI Stage 2, n (%)

163 (27%)

73 (26%)

90 (28%)

0.337

 AKI Stage 3, n (%)

210 (35%)

109 (39%)

101 (32%)

0.001

 Renal replacement therapy, n (%)

61 (10%)

41 (15%)

20 (6%)

< 0.001

SCr at admission (µmol/L), median [IQR] (missing values, n = 94)

73 [58–95]

79 [63–110]

69 [56–86]

< 0.01

Length of intubation (days), median [IQR]

12 [6–20]

13 [6–22]

13 [7–21]

0.6

Length of sedation (days), median [IQR]

10 [3–18]

10 [3–19]

8 [3–17]

0.13

ICU length of stay (days), median [IQR]

9 [5–19]

11 [5–24]

8 [4–17]

< 0.01

ICU death, n (%)

208 (26%)

109 (33%)

99 (21%)

< 0.001

  1. AKI acute kidney injury, DXM dexamethasone, IQR interquartile range, SCr serum creatinine
  2. *According to KDIGO classification, only one criterion (serum creatinine rise or urine output decline) must be fulfilled