Variable | Patient characteristics according to three groups of diaphragm thickness evolution (: stable, atrophy, increase) using a ultrasound method | Patient characteristics according to the absence or the presence of diaphragm atrophy using a ultrasound method | |||||
---|---|---|---|---|---|---|---|
Increase, N = 41 | Stable, N = 181 | Atrophy, N = 71 | p-value2 | Non-atrophy, N = 221 | Atrophy, N = 71 | p-value3 | |
Age (years) | 67 [66, 68] | 52 [48, 65] | 55 [47, 66] | 0.2 | 62 [48, 67] | 55 [47, 66] | 0.8 |
Sex (male) | 4 [100%] | 15 [83%] | 6 [86%] | > 0.9 | 19 [86%] | 6 [86%] | > 0.9 |
Weight (kg) | 90 [83, 93] | 80 [64, 98] | 85 [73, 86] | 0.7 | 81 [66, 96] | 85 [73, 86] | > 0.9 |
Height (m) | 1.79 [1.73, 1.84] | 1.75 [1.7, 1.8] | 1.7 [1.7, 1.75] | 0.5 | 1.75 [1.7, 1.8] | 1.7 [1.7, 1.75] | 0.4 |
Body Mass Index | 28 [25, 29] | 26 [23, 30] | 26 [25, 28] | 0.9 | 26 [23, 29] | 26 [25, 28] | 0.8 |
SOFA | 9 [7, 11] | 9 [6, 10] | 9 [8, 16] | 0.5 | 9 [6, 10] | 9 [8, 16] | 0.3 |
Severe Acute Physiology Score II | 47 [45, 49] | 43 [36, 51] | 47 [40, 62] | 0.6 | 44 [41, 51] | 47 [40, 62] | 0.6 |
Cardiac arrest | 0 (0%) | 9 (50%) | 3 (43%) | 0.3 | 9 (41%) | 3 (43%) | > 0.9 |
Cardiac surgery | 2 (50%) | 6 (33%) | 4 (57%) | 0.5 | 8 (36%) | 4 (57%) | 0.4 |
COPD | 1 (25%) | 1 (5.6%) | 0 (0%) | 0.3 | 2 (9.1%) | 0 (0%) | > 0.9 |
Cancer | 1 (25%) | 1 (5.6%) | 0 (0%) | 0.3 | 2 (9.1%) | 0 (0%) | > 0.9 |
Chronic kidney insufficiency | 1 (25%) | 0 (0%) | 0 (0%) | 0.14 | 1 (4.5%) | 0 (0%) | > 0.9 |
Dialysis | 1 (25%) | 2 (11%) | 2 (29%) | 0.5 | 3 (14%) | 2 (29%) | 0.6 |
Fluid balance at inclusion (ml) | − 346 [− 718, 178] | − 273 [-900, 486] | 304 [− 936, 1,227] | 0.9 | − 273 [− 900, 486] | 304 [− 936, 1,227] | 0.7 |
Weight balance J0 to last assessment (kg) | 4 [2, 4] | 0 [-4, 2] | − 1 [− 7, 3] | 0.4 | 1 [− 3, 4] | − 1 [− 7, 3] | 0.6 |
KDIGO | |||||||
I | 2 (50%) | 13 (72%) | 3 (43%) | 0.4 | 15 (68%) | 3 (43%) | 0.4 |
II | 0 (0%) | 1 (5.6%) | 0 (0%) | 1 (4.5%) | 0 (0%) | ||
III | 2 (50%) | 4 (22%) | 4 (57%) | 6 (27%) | 4 (57%) | ||
Sepsis | 0 (0%) | 1 (5.6%) | 1 (14%) | 0.6 | 1 (4.5%) | 1 (14%) | 0.4 |
Number of MV days at day 7 | 2 [1, 4] | 2 [1, 5] | 6 [5, 7] | 0.034 | 2 [1, 5] | 6 [5, 7] | 0.011 |
VA-ECMO parameters (All following parameters were averaged over the three first days) | |||||||
VA-ECMO Flow (l/min) | 2.9 [2.9, 3] | 3.5 [2, 4] | 4.5 [3, 5] | 0.3 | 3.2 [2.5, 3.9] | 4.5 [3, 5.3] | 0.2 |
Sweep gas flow (l/min) | 3 [2.7, 3.2] | 3.1 [2.6, 4] | 4.8 [3, 5] | 0.12 | 3 [2.7, 4] | 4.8 [3.3, 5] | 0.045 |