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Table 3 Hemodynamic and echocardiographic variables during fluid expansion in responders and non-responders

From: Effect of volume infusion on left atrial strain in acute circulatory failure

 

Fluid responders (n = 17)

Non-responders (n = 21)

 

Before fluid bolus

After fluid bolus

p

Before fluid bolus

After fluid bolus

p

HR – bpm

SAP – mmHg

95 [75–103]

110 [91–121]

95 [76–104]

120 [111–133]

0.91

< 0.001

102 [81–115]

110 [91–120]

98 [80–110]

115 [101–138]

0.05

0.004

DAP – mmHg

54 [50–63]

60 [54–70]

0.001

55 [45–58]

55 [51–66]

0.006

MAP – mmHg

LVEF – %

LVEDV – mL

LVESV - mL

73 [65–80]

54 [51–59]

82 [64–95]

37 [32–47]]

81 [77–88]

55 [50–60]

89 [76–96]

37 [32–48]

< 0.001

0.84

0.30

0.48

72 [64–78]

54 [43–60]

105 [80–129]

50 [33–62]

74 [68–83]

51 [41–58]

102 [80–120]

48 [40–68]

0.03

0.93

0.56

0.45

LVOT-VTI mean – cm

20 [16–26]

23 [20–29]

< 0.001

22 [15–26]

20 [15–26]

0.69

GLS-LV – % [32 pts]

E – cm/s

DTE – ms

A – cm/s

E/A

E’ lat – cm/s

E/E’

LA area – cm2

LA volume – mL

LAVI – mL/m2

LAEF - %

-12.6 [-14.1 – -10.6]

73 [60–86]

249 [223–267]

77 [58–89]

0.95 [0.78–1.09]

10 [9–12]

7.0 [5.3–9.6]

16 [13–16]

33 [18–42]

20 [10–6]

53 [41–62]

-14.6 [-16.9 – -11.6]

80 [69–95]

220 [187–264]

74 [59–91]

1.04 [0.89–1.21]

10 [8–13]

7.4 [5.9–10.1]

18 [15–22]

34 [23–43]

23 [13–28]

60 [52–67]

0.04

< 0.001

0.51

0.08

0.27

0.55

0.07

0.01

0.63

0.64

0.08

-9.5 [-14.6 – -6.6]

70 [85–61]

151 [125–235]

73 [60–93]

0.94 [0.74–1.28]

10 [6–13]

7.4 [6.3–9.3]

18 [15–23]

42 [29–53]

20 [16–27]

54 [44–58]

-13.7 [-17.8 – -8.3]

74 [57–101]

191 [158–238]

78 [60–96]

0.94 [0.75–1.29]

10 [6–13]

8.3 [5.8–11.1]

18 [15–20]

43 [27–58]

19 [13–31]

57 [43–59]

0.13

0.25

0.30

0.97

0.53

0.29

0.37

0.28

0.67

0.62

0.98

LASr mean – % [36 pts]

18 [15–33]

25 [19–34]

0.005

19 [14–31]

25 [18–36]

0.007

LAScd mean – % [36 pts]

-10 [-21 – -6]

-12 [-20 – -9]

0.13

-9[-18 – -7]

-13 [-21 – -8]

0.03

LASct mean – % [36 pts]

-8 [-14 – -6]

-11 [-16 – -8]

0.02

-9 [-14 – -4]

-10 [-16 – -6]

0.40

  1. * Data are expressed as number (percentage) or median (interquartile range). ). HR indicates Heart Rate; bpm, beats per minute; SAP, Systolic Arterial Pressure; DAP, Diastolic Arterial Pressure; MAP, Mean Arterial Pressure; LVEF, Left ventricular ejection fraction; LVEDV, left ventricular end diastolic volume; LVESV, left ventricular end systolic volume; LVOT-VTI, Left ventricle outflow tract - velocity-time integral; CO, Cardiac Output; GLS-LV, global longitudinal strain – left ventricle; E-wave early diastole; A, A-wave, atrial contraction; DTE, deceleration time E-wave; E’ lat, lateral early diastolic annulus relaxation velocity; LA, left atrium; LAVI, left atrial volume index; LAEF, left atrial ejection fraction; LAS, left atrial strain; LASr, LAS reservoir; LAScd, LAS conduit; LASct, LAS contraction