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Table 3 Comparison of different clinical, hemodynamic and perfusion variables at baseline in CRT-responders versus non-responders to the vasopressor test

From: Capillary refill time response to a fluid challenge or a vasopressor test: an observational, proof-of-concept study

 

Responders

Non-responders

p-value

Number of patients

14

11

 

Age (years)

76 [66–81]

68 [66–78]

0.3

APACHE

20 ± 9.3

19.6 ± 5.7

0.9

SOFA

9.3 ± 2.4

9.4 ± 2.6

0.34

CRP (mg/dL)

31.1 ± 14.5

20.4 ± 16.3

0.004

CO (L/min)

3.9 ± 1.2

5.5 ± 1.3

0.047

NE dose (mcg/kg/min)

0.13 ± 0.11

0.24 ± 0.13

0.12

CVP (mmHg)

7.4 ± 4.4

11 ± 5.1

0.7

HR (bpm)

86 ± 15

89 ± 16

0.056

CRT (s)

5.0 [3.8–6.5]

3.7 [3–5]

0.49

Lactate (mmol/L)

2.5 [2-3.3]

3.8 [1.6–8.8]

0.1

Central venous O2 saturation (%)

69 [65–84]

82 [74–85]

0.7

Venous-arterial pCO2 gradient (mmHg)

3 [1–4]

3 [3–6]

0.8

  1. APACHE: Acute Physiology and Chronic Health Evaluation; SOFA: Sequential Organ Failure Assessment; APACHE: Acute Physiology and Chronic Health Evaluation; CRP: c-reactive protein; CO: cardiac output; NE: norepinephrine; CVP: central venous pressure; HR: heart rate; CRT: capillary refill time. Data is presented as mean +- SD or median [interquartile range]. Students’ t-test or Mann-Whitney U-test used accordingly