Table 2 Patient Characteristics
From: Gut barrier dysfunction and the risk of ICU-acquired bacteremia- a case–control study
Variables | Cases | Controls | P Value | ||
|---|---|---|---|---|---|
N = 72 | N = 137 | ||||
Patient characteristics at baseline | |||||
Age (years) | 63 | (51–70) | 63 | (52–69) | MF |
Male | 50 | (69.4) | 94 | (68.6) | 0.90 |
Charlson comorbidity index | 3 | (2–4) | 3 | (1–4) | 0.25 |
Immunodeficiency | 16 | (22.2) | 25 | (18.3) | 0.50 |
Mucositis or intestinal GvHD | 5 | (6.9) | 4 | (2.9) | 0.17 |
Previously admitted to ICU | 12 | (16.7) | 18 | (13.1) | 0.49 |
Surgical reason for admission | 29 | (40.3) | 47 | (34.3) | 0.39 |
Sepsis at admission | 22 | (30.6) | 31 | (22.6) | 0.21 |
APACHE IV score | 88.5 | (65–104) | 86 | (68–102) | 0.94 |
ICU outcomes | |||||
Total length of ICU stay (days) | 16 | (9.5–26) | 16 | (10–26) | 0.81 |
ICU mortality | 33 | (45.8) | 42 | (30.7) | 0.03 |
Patient characteristics at bacteremia onseta | |||||
Days in ICU | 7 | (5–12.5) | 8 | (5–12) | MF |
SOFA score | 7 | (4.5–12.5) | 7 | (4–11) | 0.14 |
Acute kidney injury | 28 | (38.9) | 51 | (37.2) | MF |
Catecholamine use | 39 | (54.2) | 68 | (49.6) | 0.53 |
C-reactive protein (mg/L) | 107 | (63–222) | 112 | (64–182) | 0.80 |
Indwelling catheters | |||||
Arterial catheter | 68 | (94.4) | 133 | (97.1) | 0.35 |
CVC | 59 | (81.9) | 100 | (73.0) | 0.15 |
Pulmonary catheter | 1 | (1.4) | 9 | (6.6) | 0.10 |
RRT | 24 | (33.3) | 38 | (27.7) | MF |
Plasma biomarkers | |||||
I-FABP (pg/ml) | 1056 | (669–1820) | 947 | (545–1666) | 0.21 |
TFF3 (ng/ml) | 27.0 | (12.4–47.9) | 21.3 | (11.3–43.4) | 0.38 |
Citrulline (µmol/L) | 25.8 | (19.4–34.1) | 25.3 | (17.6–34.5) | 0.84 |
GIF-scorea,b ≥ 2 | 20 | (27.8) | 32 | (23.4) | 0.59 |