Impact of therapeutic plasmapheresis on the duration of organ failure in patients with hypertriglyceridemia-associated acute pancreatitis

Annals of Intensive Care

Table 2 Clinical outcomes

	Medical N = 76	Plasmapheresis N = 46	Effect estimate^a (95% CI)	P value
Primary outcome
Time to organ failure resolution, d	4.00 (0.25–8.75)	4.00 (2.00–7.00)	HR, 1.07 (0.68 to 1.68)	0.777
Secondary outcomes
Requirement of ICU admission	50 (65.8)	45 (97.8)	OR, 19.33 (2.20 to 169.81)	0.008
28-day mortality	2 (2.6)	2 (4.3)	OR, 0.67 (0.04 to 11.49)	0.785
60-day mortality	4 (5.3)	6 (13.0)	OR, 1.84 (0.35 to 9.61)	0.468
ICU-free days to day14, d	10.00 (2.25–14.00)	7.00 (2.00–10.00)	β, 0.85 (− 1.94 to 3.64)	0.547
Length of hospital stay, d	11.00 (7.00–18.75)	14.50 (9.75–20.25)	β, − 0.99 (− 5.58 to 3.61)	0.672

ICU intensive care unit, HR hazard ratio, OR odds ratio, β coefficient, CI confidence interval
^aCox regression model or Logistic regression model or Median regression model with the adjustment of APACHEII, Baseline triglyceride, respiratory failure, cardiovascular failure, and renal failure