Oxygenation management during veno-arterial ECMO support for cardiogenic shock: a multicentric retrospective cohort study

Annals of Intensive Care

Table 2 Description of oxygenation parameters among the 139 patients supported by peripheral VA ECMO

Oxygenation parameters	F_SO₂ (%)		F_IO₂ (%)		Right radial P_aO₂ (mmHg)
Mean value
From day 1 to day 7 From day 1 to day 3	70 [57;79] 70 [60;80]		44 [35;57] 45 [35;60]		114 [92;145] 117 [90;158]
Daily evolution
Day 1 (n = 139) Day 2 (n = 136) Day 3 (n = 132) Day 4 (n = 117) Day 5 (n = 97) Day 6 (n = 78) Day 7 (n = 68)	70 [60;80]* 70 [60;80] 70 [57;80]* 70 [60;80] 70 [60;80] 70 [60;80] 70 [59;80]		50 [37;70] 40 [30;60] 40 [30;60] 40 [30;60] 40 [33;53] 40 [30;50] 40 [30;50]		125 [86;207]* 106 [78;139] 97 [81;133]* 94 [79;116] 96 [79;129] 88 [78;114] 95 [80;136]
Center case volume (per year)	F_SO₂ _{mean (day 1−7)}		F_IO₂ _{mean (day 1−7)}		Right radial P_aO₂ _{mean (day 1−7)}
< 30 30–100 > 100	72 [70;81] 69 [57;78] 55 [44;69]	p < 0.01	46 [38;57] 47 [35;59] 36 [30;46]	p = 0.18	115 [92;155] 116 [96;147] 98 [87;112]	p = 0.04
Extubation during ECMO support	F_SO₂ _{mean (day 1−7)}		F_IO₂ _{mean (day 1−7)}		Right radial P_aO₂ _{mean (day 1−7)}
Yes No	66 [50;76] 70 [59;80]	p = 0.04	34 [29;39] 51 [42;64]	p < 0.01	102 [87;122] 118 [97;151]	p = 0.01

Data are median [Interquartile range]; F_SO₂: sweep gas oxygen fraction; F_IO₂: inspired oxygen fraction; p: p value
*Comparison between F_SO_{2 day 1} and F_SO_{2 day 3}: p = 0.37
** Comparison between F_IO_{2 day 1} and F_IO_{2 day 3}: p < 0.01
*** Comparison between right radial P_aO_{2 day 1} and right radial P_aO_{2 day 3}: p < 0.01