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Table 3 Univariate and multivariate analyses of factors associated with in-ICU mortality among the 139 patients supported by peripheral VA ECMO

From: Oxygenation management during veno-arterial ECMO support for cardiogenic shock: a multicentric retrospective cohort study

 

Univariate analysis

Multivariate analysis

Patients characteristics

Survivors

(n = 87)

Non-survivors

(n = 52)

p value

OR [CI 95%]

p value

Age (years)

52 [45;59]

62 [57;67]

< 0.01

1.07 [1.03–1.11]

< 0.001

SAPS2 score

56 [45;67]

72 [48;81]

< 0.01

-

-

SOFA score

10 [7;12]

11 [8;13]

0.23

-

-

Center case-volume (VA ECMO/year)

< 30

20/87

12/52

0.28

  

30–100

52/87

36/52

-

-

> 100

15/87

4/52

  

ECMO duration (days)

6 [4;9]

7 [4;8]

0.6

-

-

FSO2  day 1 (%)

65 [60;80]

70 [60;90]

0.11

-

-

FSO2 day 2 (%)

65 [50;78]

70 [60;80]

0.02

-

-

FSO2 day 3 (%)

70 [51;75]

75 [65;84]

< 0.01

-

-

FSO2 mean (day 1−3) (%)

67 [54;75]

72 [65;85]

< 0.01

1.03 [1.00-1.06]

0.039

FSO2 day 1 > 70%*

51/87

34/52

0.48

-

-

FSO2 day 2 > 70%*

49/87

37/49

0.03

-

-

FSO2 day 3 > 70%*

47/86

35/46

0.02

-

-

FSO2 day 1−3 > 70%*

39/87

33/52

0.04

-

-

Right radial PaO2  day 1 (mmHg)

120 [88;183]

165 [82;242]

0.21

-

-

Right radial PaO2  day 2 (mmHg)

99 [77;128]

114 [86;156]

0.06

-

-

Right radial PaO2  day 3 (mmHg)

94 [81;120]

109 [82;162]

0.08

-

-

Right radial PaO2  mean (day 1−3) (mmHg)

111 [90;146]

141 [100;197]

0.01

1.03 [1.00-1.02]

0.023

  1. Data are number and median [Interquartile range] OR: Odds ratio; CI95%: confidence interval; SAPS2: simplified acute; FSO2: Sweep gas oxygen fraction
  2. * FSO2 day X > 70% corresponds to at least one FSO2 value > 70% on day X
  3. Bold values are p values < 0.05