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Table 3 Diagnosis criteria, characteristics and antifungal therapy of patients (n = 29) diagnosed with Coronavirus disease (COVID-19)-associated pulmonary aspergillosis (CAPA)

From: COVID-19 associated pulmonary aspergillosis in critically-ill patients: a prospective multicenter study in the era of Delta and Omicron variants

Variable

CAPA patients, n = 29

CAPA diagnosis criteria

 CAPA proven/probable

24 (83)

 CAPA possible

5 (17)

Time from ICU admission to CAPA diagnosis, days

5 [2–16]

Immunosuppression

15 (52)

 Haematological malignancies

10 (66)

 Solid organ transplantation

4 (27)

 Immunosuppressive drugs

1 (7)

IMV

22 (76)

 Time from IMV to CAPA diagnosis, days

6 [2–13]

Antifungal therapy

28 (97)

 Azole antifungals

28 (100)

  Voriconazole

24 (86)

  Isavuconazole

4 (14)

  Itraconazole

1 (4)

  Posaconazole

1 (4)

 Caspofungin

2 (7)

 Liposomal amphotericin B

2 (7)

  1. Results are N (%), means (± standard deviation) or medians (interquartile range, i.e., quartile 1; quartile 3)
  2. CAPA COVID-19-associated pulmonary aspergillosis, ICU intensive care unit, IMV invasive mechanical ventilation