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  1. Content type: Research

    One third of patients admitted to an intensive care unit (ICU) will develop delirium. However, delirium is under-recognized by bedside clinicians without the use of delirium screening tools, such as the Intens...

    Authors: Gérald Chanques, E. Wesley Ely, Océane Garnier, Fanny Perrigault, Anaïs Eloi, Julie Carr, Christine M. Rowan, Albert Prades, Audrey de Jong, Sylvie Moritz-Gasser, Nicolas Molinari and Samir Jaber

    Citation: Annals of Intensive Care 2018 8:33

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  2. Content type: Correction

    Upon publication of the original article [1], it was noticed that the title was incorrect. Instead of ‘critical’, it should read ‘critically’, and therefore, the correct title should be.

    Authors: Antoine Dewitte, Sébastien Lepreux, Julien Villeneuve, Claire Rigothier, Christian Combe, Alexandre Ouattara and Jean Ripoche

    Citation: Annals of Intensive Care 2018 8:32

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    The original article was published in Annals of Intensive Care 2017 7:115

  3. Content type: Research

    The Extracorporeal Life Support Organization (ELSO) has suggested that extracorporeal membrane oxygenation (ECMO) patients should be managed by a multidisciplinary team. However, there are limited data on the ...

    Authors: Soo Jin Na, Chi Ryang Chung, Hee Jung Choi, Yang Hyun Cho, Kiick Sung, Jeong Hoon Yang, Gee Young Suh and Kyeongman Jeon

    Citation: Annals of Intensive Care 2018 8:31

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  4. Content type: Research

    Duration of acute kidney injury (AKI) has been recognized a risk factor for adverse outcomes following AKI. We sought to examine the relationship of AKI duration and recurrent AKI with short-term outcomes in c...

    Authors: Christine K. Federspiel, Theis S. Itenov, Kala Mehta, Raymond K. Hsu, Morten H. Bestle and Kathleen D. Liu

    Citation: Annals of Intensive Care 2018 8:30

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  5. Content type: Research

    In critical patients, left ventricular ejection fraction and fractional shortening are used to reflect left ventricular systolic function. An emerging technique, two-dimensional-strain echocardiography, allows...

    Authors: C. Nafati, M. Gardette, M. Leone, L. Reydellet, V. Blasco, A. Lannelongue, F. Sayagh, S. Wiramus, F. Antonini, J. Albanèse and L. Zieleskiewicz

    Citation: Annals of Intensive Care 2018 8:29

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  6. Content type: Review

    The majority of resuscitated patients present with underlying cardiac disease, and out of these myocardial infarction is most common. Immediate interventional treatment is recommended and routinely requires du...

    Authors: Florian Prüller, Oliver Leopold Milke, Lukasz Bis, Friedrich Fruhwald, Daniel Scherr, Philipp Eller, Sascha Pätzold, Siegfried Altmanninger-Sock, Peter Rainer, Jolanta Siller-Matula and Dirk von Lewinski

    Citation: Annals of Intensive Care 2018 8:28

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  7. Content type: Research

    Outcome data on fluid therapy in critically ill patients from randomised controlled trials may be different from data obtained by observational studies under “real-life” conditions. We conducted this prospecti...

    Authors: Christian Ertmer, Bernhard Zwißler, Hugo Van Aken, Michael Christ, Fabian Spöhr, Axel Schneider, Robert Deisz and Matthias Jacob

    Citation: Annals of Intensive Care 2018 8:27

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  8. Content type: Research

    Most studies of acute kidney injury (AKI) have focused on older adults, and little is known about AKI in young adults (16–25 years) that are cared for in an adult intensive care unit (ICU). We analyzed data fr...

    Authors: Dana Y. Fuhrman, Sandra Kane-Gill, Stuart L. Goldstein, Priyanka Priyanka and John A. Kellum

    Citation: Annals of Intensive Care 2018 8:26

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  9. Content type: Research

    The use of positive end-expiratory pressure (PEEP) and prone position (PP) is common in the management of severe acute respiratory distress syndrome patients (ARDS). We conducted this study to analyze the vari...

    Authors: Hernan Aguirre-Bermeo, Marta Turella, Maddalena Bitondo, Juan Grandjean, Stefano Italiano, Olimpia Festa, Indalecio Morán and Jordi Mancebo

    Citation: Annals of Intensive Care 2018 8:25

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  10. Content type: Research

    Sodium lactate seemed to improve fluid balance and avoid fluid overload. The objective of this study was to determine if these beneficial effects can be at least partly explained by an improvement in dissemina...

    Authors: Thibault Duburcq, Arthur Durand, Antoine Tournoys, Viviane Gnemmi, Valery Gmyr, François Pattou, Mercedes Jourdain, Fabienne Tamion, Emmanuel Besnier, Sebastien Préau, Erika Parmentier-Decrucq, Daniel Mathieu, Julien Poissy and Raphaël Favory

    Citation: Annals of Intensive Care 2018 8:24

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  11. Content type: Research

    Mesenchymal stem cells (MSC) obviously alleviate the damage of the structure and function of pulmonary vascular endothelial cells (VEC). The therapeutic effects of MSC are significantly different between pulmo...

    Authors: Yi Zheng, Song-qiao Liu, Qin Sun, Jian-feng Xie, Jing-yuan Xu, Qing Li, Chun Pan, Ling Liu and Ying-zi Huang

    Citation: Annals of Intensive Care 2018 8:23

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  12. Content type: Review

    Acute kidney injury (AKI) is a common complication in patients undergoing major abdominal surgery. Various recent studies using modern standardized classifications for AKI reported a variable incidence of AKI ...

    Authors: Joana Gameiro, José Agapito Fonseca, Marta Neves, Sofia Jorge and José António Lopes

    Citation: Annals of Intensive Care 2018 8:22

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  13. Content type: Review

    Patients who increase stoke volume or cardiac index more than 10 or 15% after a fluid challenge are usually considered fluid responders. Assessment of fluid responsiveness prior to volume expansion is critical...

    Authors: Renato Carneiro de Freitas Chaves, Thiago Domingos Corrêa, Ary Serpa Neto, Bruno de Arruda Bravim, Ricardo Luiz Cordioli, Fabio Tanzillo Moreira, Karina Tavares Timenetsky and Murillo Santucci Cesar de Assunção

    Citation: Annals of Intensive Care 2018 8:21

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  14. Content type: Research

    Delayed cerebral thrombosis (DCT) is a devastating cerebrovascular complication in patients with excellent initial recovery of pneumococcal meningitis. The aetiology is unknown, but direct bacterial invasion, ...

    Authors: Joo-Yeon Engelen-Lee, Matthijs C. Brouwer, Eleonora Aronica and Diederik van de Beek

    Citation: Annals of Intensive Care 2018 8:20

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  15. Content type: Research

    Medication errors occur frequently in the intensive care unit (ICU) and during care transitions. Chronic medication is often temporarily stopped at the ICU. Unfortunately, when the patient improves, the restar...

    Authors: Liesbeth B. E. Bosma, Nicole G. M. Hunfeld, Rogier A. M. Quax, Edmé Meuwese, Piet H. G. J. Melief, Jasper van Bommel, SiokSwan Tan, Maaike J. van Kranenburg and Patricia M. L. A. van den Bemt

    Citation: Annals of Intensive Care 2018 8:19

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  16. Content type: Research

    Identifying patients at high risk of post-extubation acute respiratory failure requiring respiratory or mechanical cough assistance remains challenging. Here, our primary aim was to evaluate the accuracy of ea...

    Authors: Nicolas Terzi, Frédéric Lofaso, Romain Masson, Pascal Beuret, Hervé Normand, Edith Dumanowski, Line Falaize, Bertrand Sauneuf, Cédric Daubin, Jennifer Brunet, Djillali Annane, Jean-Jacques Parienti and David Orlikowski

    Citation: Annals of Intensive Care 2018 8:18

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  17. Content type: Research

    To explore potential design for pharmacogenomics trials in sepsis, we investigate the interaction between pharmacogenomic biomarkers and response to drotrecogin alfa (activated) (DrotAA). This trial was desig...

    Authors: Djillali Annane, Jean-Paul Mira, Lorraine B. Ware, Anthony C. Gordon, Charles J. Hinds, David C. Christiani, Jonathan Sevransky, Kathleen Barnes, Timothy G. Buchman, Patrick J. Heagerty, Robert Balshaw, Nadia Lesnikova, Karen de Nobrega, Hugh F. Wellman, Mauricio Neira, Alexandra D. J. Mancini…

    Citation: Annals of Intensive Care 2018 8:16

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  18. Content type: Research

    Hypoxic hepatitis (HH) is a type of acute hepatic injury that is histologically characterized by centrilobular liver cell necrosis and that is caused by insufficient oxygen delivery to the hepatocytes. Typical...

    Authors: Astrid Van den broecke, Laura Van Coile, Alexander Decruyenaere, Kirsten Colpaert, Dominique Benoit, Hans Van Vlierberghe and Johan Decruyenaere

    Citation: Annals of Intensive Care 2018 8:15

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  19. Content type: Research

    Assessment of maximum respiratory pressures is a common practice in intensive care because it can predict the success of weaning from ventilation. However, the reliability of measurements through an intubation...

    Authors: Clément Medrinal, Guillaume Prieur, Yann Combret, Aurora Robledo Quesada, Tristan Bonnevie, Francis Edouard Gravier, Eric Frenoy, Olivier Contal and Bouchra Lamia

    Citation: Annals of Intensive Care 2018 8:14

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  20. Content type: Research

    To explore the feasibility of transcutaneous electromyographic respiratory muscle recordings to automatically quantify the synchronicity of patient–ventilator interaction in the pediatric intensive care unit.

    Authors: Alette A. Koopman, Robert G. T. Blokpoel, Leo A. van Eykern, Frans H. C. de Jongh, Johannes G. M. Burgerhof and Martin C. J. Kneyber

    Citation: Annals of Intensive Care 2018 8:12

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  21. Content type: Research

    Weaning protocols expedite extubation in mechanically ventilated patients, yet the literature investigating the application in tracheostomized patients remains scarce. The primary objective of this parallel ra...

    Authors: Nazzareno Fagoni, Simone Piva, Elena Peli, Fabio Turla, Elisabetta Pecci, Livio Gualdoni, Bertilla Fiorese, Frank Rasulo and Nicola Latronico

    Citation: Annals of Intensive Care 2018 8:11

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  22. Content type: Research

    Stool cultures for Campylobacter, Salmonella and Shigella and/or Yersinia spp. are frequently ordered in critically ill patients with diarrhea. The aim of this study is to analyze the diagnostic yield in a large ...

    Authors: Carolin F. Manthey, Darja Dranova, Martin Christner, Laura Berneking, Stefan Kluge, Ansgar W. Lohse and Valentin Fuhrmann

    Citation: Annals of Intensive Care 2018 8:10

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  23. Content type: Research

    Statins can exert pleiotropic anti-inflammatory, vascular protective and anticoagulant effects, which in theory could improve the dysregulated host response during sepsis. We aimed to determine the association...

    Authors: Maryse A. Wiewel, Brendon P. Scicluna, Lonneke A. van Vught, Arie J. Hoogendijk, Aeilko H. Zwinderman, René Lutter, Janneke Horn, Olaf L. Cremer, Marc J. Bonten, Marcus J. Schultz and Tom van der Poll

    Citation: Annals of Intensive Care 2018 8:9

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  24. Content type: Research

    Furosemide responsiveness (FR) is determined by urine output after furosemide administration and has recently been evaluated as a furosemide stress test (FST) for predicting severe acute kidney injury (AKI) pr...

    Authors: Ryo Matsuura, Yohei Komaru, Yoshihisa Miyamoto, Teruhiko Yoshida, Kohei Yoshimoto, Rei Isshiki, Kengo Mayumi, Tetsushi Yamashita, Yoshifumi Hamasaki, Masaomi Nangaku, Eisei Noiri, Naoto Morimura and Kent Doi

    Citation: Annals of Intensive Care 2018 8:8

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  25. Content type: Research

    There is no consensus on the management of anticoagulation during extracorporeal membrane oxygenation (ECMO). ECMO is currently burdened by a high rate of hemostatic complications, possibly associated with ina...

    Authors: Mauro Panigada, Giacomo E. Iapichino, Matteo Brioni, Giovanna Panarello, Alessandro Protti, Giacomo Grasselli, Giovanna Occhipinti, Cristina Novembrino, Dario Consonni, Antonio Arcadipane, Luciano Gattinoni and Antonio Pesenti

    Citation: Annals of Intensive Care 2018 8:7

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  26. Content type: Research

    To evaluate the efficacy of using internal jugular vein variability (IJVV) as an index of fluid responsiveness in mechanically ventilated patients after cardiac surgery.

    Authors: Guo-guang Ma, Guang-wei Hao, Xiao-mei Yang, Du-ming Zhu, Lan Liu, Hua Liu, Guo-wei Tu and Zhe Luo

    Citation: Annals of Intensive Care 2018 8:6

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  27. Content type: Research

    The acute respiratory distress syndrome (ARDS) is a life-threatening condition. In special situations, these critically ill patients must be transferred to specialized centers for escalating treatment. The aim...

    Authors: Sebastian Blecha, Frank Dodoo-Schittko, Susanne Brandstetter, Magdalena Brandl, Michael Dittmar, Bernhard M. Graf, Christian Karagiannidis, Christian Apfelbacher and Thomas Bein

    Citation: Annals of Intensive Care 2018 8:5

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  28. Content type: Research

    Hyperglycaemia is commonplace in the adult intensive care unit (ICU), associated with increased morbidity and mortality. Effective glycaemic control (GC) can reduce morbidity and mortality, but has proven diff...

    Authors: Kent W. Stewart, J. Geoffrey Chase, Christopher G. Pretty and Geoffrey M. Shaw

    Citation: Annals of Intensive Care 2018 8:4

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  29. Content type: Research

    Middle East respiratory syndrome (MERS) is caused by a coronavirus (MERS‐CoV) and is characterized by hypoxemic respiratory failure. The objective of this study is to compare the outcomes of MERS-CoV patients ...

    Authors: Mohammed S. Alshahrani, Anees Sindi, Fayez Alshamsi, Awad Al-Omari, Mohamed El Tahan, Bayan Alahmadi, Ahmed Zein, Naif Khatani, Fahad Al-Hameed, Sultan Alamri, Mohammed Abdelzaher, Amenah Alghamdi, Faisal Alfousan, Adel Tash, Wail Tashkandi, Rajaa Alraddadi…

    Citation: Annals of Intensive Care 2018 8:3

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  30. Content type: Research

    Cardiac dysfunction is a common cause of weaning failure. Weaning shares some similarities with a cardiac stress test and may challenge active phases of the cardiac cycle-like ventricular contractility and rel...

    Authors: Ferran Roche-Campo, Alexandre Bedet, Emmanuel Vivier, Laurent Brochard and Armand Mekontso Dessap

    Citation: Annals of Intensive Care 2018 8:2

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  31. Content type: Research

    The early prediction of the severity of acute pancreatitis still represents a challenge for clinicians. Experimental studies have revealed the generation of specific halogenated lipids, in particular oleic aci...

    Authors: Enrique de-Madaria, Xavier Molero, Laia Bonjoch, Josefina Casas, Karina Cárdenas-Jaén, Andrea Montenegro and Daniel Closa

    Citation: Annals of Intensive Care 2018 8:1

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  32. Content type: Research

    We aimed (1) to describe the characteristics of patient–ventilator asynchrony in a population of critically ill children, (2) to describe the risk factors associated with patient–ventilator asynchrony, and (3)...

    Authors: Guillaume Mortamet, Alexandrine Larouche, Laurence Ducharme-Crevier, Olivier Fléchelles, Gabrielle Constantin, Sandrine Essouri, Amélie-Ann Pellerin-Leblanc, Jennifer Beck, Christer Sinderby, Philippe Jouvet and Guillaume Emeriaud

    Citation: Annals of Intensive Care 2017 7:122

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  33. Content type: Research

    Left ventricular diastolic dysfunction is suggested to be associated with higher mortality in severe sepsis and septic shock, yet the methods of diagnosis described in the literature are often inconsistent. Th...

    Authors: David J. Clancy, Timothy Scully, Michel Slama, Stephen Huang, Anthony S. McLean and Sam R. Orde

    Citation: Annals of Intensive Care 2017 7:121

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  34. Content type: Research

    Among intensive care unit (ICU) patients with acute respiratory distress syndrome (ARDS), apart from acute cor pulmonale (ACP), the frequency and prognostic impact of basic critical care echocardiography (BCCE...

    Authors: Kay Choong See, Jeffrey Ng, Wen Ting Siow, Venetia Ong and Jason Phua

    Citation: Annals of Intensive Care 2017 7:120

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  35. Content type: Research

    Patients with malignant haematological disease and especially those who require intensive care have an increased risk of bleeding and thrombosis, but none of these data were obtained in ICU patients only. We a...

    Authors: Lene Russell, Lars Broksø Holst, Lars Kjeldsen, Jakob Stensballe and Anders Perner

    Citation: Annals of Intensive Care 2017 7:119

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  36. Content type: Research

    Septic shock-induced disseminated intravascular coagulation is responsible for increased occurrence of multiple organ dysfunction and mortality. Immunothrombosis-induced coagulopathy may contribute to hypercoa...

    Authors: Julie Helms, Raphaël Clere-Jehl, Elsa Bianchini, Pierrick Le Borgne, Mélanie Burban, Fatiha Zobairi, Jean-Luc Diehl, Lelia Grunebaum, Florence Toti, Ferhat Meziani and Delphine Borgel

    Citation: Annals of Intensive Care 2017 7:118

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  37. Content type: Review

    Host infection by a micro-organism triggers systemic inflammation, innate immunity and complement pathways, but also haemostasis activation. The role of thrombin and fibrin generation in host defence is now re...

    Authors: Xavier Delabranche, Julie Helms and Ferhat Meziani

    Citation: Annals of Intensive Care 2017 7:117

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  38. Content type: Research

    Impact of metformin exposure before ICU stay remains controversial. Metformin is thought to induce lactic acidosis and haemodynamic instability but may reduce ICU mortality. We evaluated its influence on outco...

    Authors: Sebastien Jochmans, Jean-Emmanuel Alphonsine, Jonathan Chelly, Ly Van Phach Vong, Oumar Sy, Nathalie Rolin, Olivier Ellrodt, Mehran Monchi and Christophe Vinsonneau

    Citation: Annals of Intensive Care 2017 7:116

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  39. Content type: Review

    Beyond haemostasis, platelets have emerged as versatile effectors of the immune response. The contribution of platelets in inflammation, tissue integrity and defence against infections has considerably widened...

    Authors: Antoine Dewitte, Sébastien Lepreux, Julien Villeneuve, Claire Rigothier, Christian Combe, Alexandre Ouattara and Jean Ripoche

    Citation: Annals of Intensive Care 2017 7:115

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    The Correction to this article has been published in Annals of Intensive Care 2018 8:32

  40. Content type: Research

    Serum procalcitonin (PCT) concentration is used to guide antibiotic decisions in choice, timing, and duration of anti-infection therapy to avoid antibiotic overuse. Thus, we performed a systematic review and m...

    Authors: Hui-Bin Huang, Jin-Min Peng, Li Weng, Chun-Yao Wang, Wei Jiang and Bin Du

    Citation: Annals of Intensive Care 2017 7:114

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  41. Content type: Review

    Several studies suggest that alternatives to carbapenems, and particulary beta-lactam/beta-lactamase inhibitor combinations, can be used for therapy of extended-spectrum beta-lactamase-producing Enterobacteria...

    Authors: Benoit Pilmis, Vincent Jullien, Alexis Tabah, Jean-Ralph Zahar and Christian Brun-Buisson

    Citation: Annals of Intensive Care 2017 7:113

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  42. Content type: Research

    An extended course of tetanus (up to 6 weeks) requiring ICU admission and protracted mechanical ventilation (MV) may have a significant impact on short- and long-term survival. The subject is noteworthy and d...

    Authors: Rafael Mahieu, Thomas Reydel, Adel Maamar, Jean-Marc Tadié, Angeline Jamet, Arnaud W. Thille, Nicolas Chudeau, Julien Huntzinger, Steven Grangé, Gaetan Beduneau, Anne Courte, Stephane Ehrmann, Jérémie Lemarié, Sébastien Gibot, Michael Darmon, Christophe Guitton…

    Citation: Annals of Intensive Care 2017 7:112

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  43. Content type: Research

    Nosocomial infections occurring during extracorporeal membrane oxygenation (ECMO) support have already been reported, but few studied infections directly related to ECMO devices. This study aims to evaluate t...

    Authors: Guillemette Thomas, Sami Hraiech, Nadim Cassir, Samuel Lehingue, Romain Rambaud, Sandrine Wiramus, Christophe Guervilly, Fanny Klasen, Mélanie Adda, Stéphanie Dizier, Antoine Roch, Laurent Papazian and Jean-Marie Forel

    Citation: Annals of Intensive Care 2017 7:111

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  44. Content type: Research

    No single anticoagulant has been proven effective for sepsis-associated disseminated intravascular coagulation (DIC). Thus, the concomitant use of antithrombin concentrate and recombinant thrombomodulin has be...

    Authors: Toshiaki Iba, Akiyoshi Hagiwara, Daizoh Saitoh, Hideaki Anan, Yutaka Ueki, Koichi Sato and Satoshi Gando

    Citation: Annals of Intensive Care 2017 7:110

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  45. Content type: Research

    Continuous aspiration of subglottic secretions is effective in preventing ventilator-associated pneumonia, but it involves a risk of mucosal damage. The main objective of our study was to determine the inciden...

    Authors: Jordi Vallés, Susana Millán, Emili Díaz, Eva Castanyer, Xavier Gallardo, Ignacio Martín-Loeches, Marta Andreu, Mario Prenafeta, Paula Saludes, Jorge Lema, Montse Batlle, Néstor Bacelar and Antoni Artigas

    Citation: Annals of Intensive Care 2017 7:109

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  46. Content type: Research

    We assessed the potential of risk stratification of ARDS patients using SpO2/FiO2 and positive end-expiratory pressure (PEEP) at ARDS onset and after 24 h.

    Authors: Luigi Pisani, Jan-Paul Roozeman, Fabienne D. Simonis, Antonio Giangregorio, Sophia M. van der Hoeven, Laura R. Schouten, Janneke Horn, Ary Serpa Neto, Emir Festic, Arjen M. Dondorp, Salvatore Grasso, Lieuwe D. Bos and Marcus J. Schultz

    Citation: Annals of Intensive Care 2017 7:108

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  47. Content type: Research

    Anemia is prevalent at pediatric intensive care unit (PICU) admission and incident during PICU stay, but little is known about anemia at PICU discharge . Anemia after critical illness is an important issue bec...

    Authors: Pierre Demaret, Oliver Karam, Marisa Tucci, Jacques Lacroix, Hélène Behal, Alain Duhamel, Frédéric Lebrun, André Mulder and Stéphane Leteurtre

    Citation: Annals of Intensive Care 2017 7:107

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  48. Content type: Research

    Ventilator-associated pneumonia (VAP) is a care-related event that could be promoted by immune suppression caused by critical diseases, malignancies and cancer treatments. Low dose of hydrocortisone was propos...

    Authors: David Lagier, Laura Platon, Jérome Lambert, Laurent Chow-Chine, Antoine Sannini, Magali Bisbal, Jean-Paul Brun, Karim Asehnoune, Marc Leone, Marion Faucher and Djamel Mokart

    Citation: Annals of Intensive Care 2017 7:106

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