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Table 4 Determinants associated with ICU-acquired pneumonia

From: Pulmonary infections prime the development of subsequent ICU-acquired pneumonia in septic shock

Variables Univariate Multivariate
CSH ratio 95% CI p CSH ratio 95% CI p
Male gender 2.14 1.41–3.25 < 0.001 2.17 1.35–3.45 0.001
Source of primary infection
 Lung Ref. Ref. Ref. Ref. Ref. Ref.
 Digestive 0.49 0.28–0.86 0.01 0.59 0.33–1.05 0.07
 Urinary 0.24 0.07–0.76 0.01 0.29 0.09–0.89 0.03
 Skin and soft tissue 0.29 0.09–0.93 0.03 0.33 0.10–1.04 0.06
 Catheter 0.36 0.11–1.14 0.08 0.47 0.15–1.48 0.19
 Others 0.43 0.20–0.88 0.02 0.49 0.23–1.02 0.05
Creatininemia 0.99 0.99–1 0.10    
SOFA score 1.03 1–1.06 0.04 1.03 1.01–1.07 0.03
Mechanical ventilation 1.16 0.47–2.84 0.75    
Aminoglycosides 0.67 0.47–0.94 0.02    
  1. All covariates were analyzed at baseline status except for mechanical ventilation which was evaluated as time-dependent covariate
  2. CSH ratio cause-specific hazard ratio, 95% CI 95% confidence interval, SOFA Sequential Organ Failure Assessment