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Annals of Intensive Care

Table 3 Blood gas parameters prior to and immediately after the first ADVOS treatment

From: Advanced organ support (ADVOS) in the critically ill: first clinical experience in patients with multiple organ failure

 

All (n = 34)

ARDS (n = 10)

Severe metabolic acidosis (n = 11)

Before

After

Before

After

Before

After

Blood gas

      

Blood pH

7.29 (7.19, 7.35)

7.40 (7.32, 7.46)**

7.21 (7.11, 7.29)

7.40 (7.33, 7.48)**

7.19 (7.09, 7.19)

7.40 (7.33, 7.45)**

HCO3− (mmol/l)

19.0 (17.5, 23.1)

22.8 (20.0, 27.4)**

24.1 (18.6, 26.7)

32.5 (28.1, 39.6)**

15.4 (13.8, 16.8)

20.4 (18.0, 24.3)**

PaCO2 (mmHg)

40.6 (32.9, 60.8)

36.8 (31.6, 43.6)**

68.8 (58.4, 73.2)

49.5 (42.3, 56.1)**

37.5 (31.0, 42.9)

36.8 (32.5, 40.6)

PaO2 (mmHg)

81.1 (65.9, 97.8)

78.6 (73.4, 93.2)

73.0 (65.0, 83.3)

84.7 (74.8, 96.9)

88.4 (61.5, 108.2)

77.6 (65.1, 84.2)

Base excess (mmol/l)

− 6.7 (− 9.3, − 1.6)

− 1.5 (− 6.6, 3.1)**

− 0.4 (− 7.0, 2.8)

7.8 (1.6, 15.5)**

− 12.4 (− 14.9, − 10.5)

− 4.9 (− 8.5, 0.9)**

Lactate (mmol/l)

2.20 (1.15, 9.40)

2.50 (1.50, 8.15)

1.90 (0.85, 3.45)

1.95 (1.75, 2.55)

9.60 (5.85, 12.60)

7.40 (5.10, 10.15)

SID (mEq/l)

31.4 (27.2, 35.4)

32.8 (27.5, 39.0)

38.7 (31.2, 40.7)

41.5 (33.4, 47.2)

23.2 (21.3, 25.7)

28.2 (24.6, 34.3)**

  1. Apart from the summary of all treatment sessions, Table 3 illustrates the blood gas parameters of two subgroups (i.e., patients with ARDS and patients with severe metabolic acidosis immediately prior to ADVOS. Median (IQ25, IQ75). Non-parametric paired Wilcoxon test. *p < 0.05, **p < 0.01
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