Vincent J-L, Lefrant J-Y, Kotfis K, Nanchal R, Martin-Loeches I, Wittebole X, et al. Comparison of European ICU patients in, 2002 (ICON) versus 2002 (SOAP. Intensive Care Med. 2012. https://doi.org/10.1007/s00134-017-5043-2.
Article
PubMed
Google Scholar
Vincent J-L, Nelson DR, Williams MD. Is worsening multiple organ failure the cause of death in patients with severe sepsis? Crit Care Med. 2011;39:1050–5. https://doi.org/10.1097/CCM.0b013e31820eda29.
Article
PubMed
Google Scholar
Hoste EAJ, Bagshaw SM, Bellomo R, Cely CM, Colman R, Cruz DN, et al. Epidemiology of acute kidney injury in critically ill patients: the multinational AKI-EPI study. Intensive Care Med. 2015;41:1411–23. https://doi.org/10.1007/s00134-015-3934-7.
Article
PubMed
Google Scholar
Drolz A, Horvatits T, Roedl K, Rutter K, Staufer K, Haider DG, et al. Outcome and features of acute kidney injury complicating hypoxic hepatitis at the medical intensive care unit. Ann Intensive Care. 2016;6:61. https://doi.org/10.1186/s13613-016-0162-4.
Article
CAS
PubMed
PubMed Central
Google Scholar
Staufer K, Roedl K, Kivaranovic D, Drolz A, Horvatits T, Rasoul-Rockenschaub S, et al. Renal replacement therapy in critically ill liver cirrhotic patients-outcome and clinical implications. Liver Int. 2017;37:843–50. https://doi.org/10.1111/liv.13389.
Article
PubMed
Google Scholar
Tujios SR, Hynan LS, Vazquez MA, Larson AM, Seremba E, Sanders CM, Lee WM. Risk factors and outcomes of acute kidney injury in patients with acute liver failure. Clin Gastroenterol Hepatol. 2015;13:352–9. https://doi.org/10.1016/j.cgh.2014.07.011.
Article
PubMed
Google Scholar
Moreau R, Jalan R, Gines P, Pavesi M, Angeli P, Cordoba J, et al. Acute-on-chronic liver failure is a distinct syndrome that develops in patients with acute decompensation of cirrhosis. Gastroenterology. 2013;144(1426–37):1437.e1–9. https://doi.org/10.1053/j.gastro.2013.02.042.
Article
Google Scholar
Du Cheyron D, Bouchet B, Parienti J-J, Ramakers M, Charbonneau P. The attributable mortality of acute renal failure in critically ill patients with liver cirrhosis. Intensive Care Med. 2005;31:1693–9. https://doi.org/10.1007/s00134-005-2842-7.
Article
PubMed
Google Scholar
Bingold TM, Lefering R, Zacharowski K, Meybohm P, Waydhas C, Rosenberger P, Scheller B. Individual organ failure and concomitant risk of mortality differs according to the type of admission to ICU—a retrospective study of SOFA Score of 23,795 patients. PLoS ONE. 2015;10:e0134329. https://doi.org/10.1371/journal.pone.0134329.
Article
CAS
PubMed
PubMed Central
Google Scholar
Audimoolam VK, McPhail MJW, Wendon JA, Willars C, Bernal W, Desai SR, Auzinger G. Lung injury and its prognostic significance in acute liver failure. Crit Care Med. 2014;42:592–600. https://doi.org/10.1097/01.ccm.0000435666.15070.d5.
Article
PubMed
Google Scholar
Fuhrmann V, Whitehouse T, Wendon J. The ten tips to manage critically ill patients with acute-on-chronic liver failure. Intensive Care Med. 2018;44:1932–5. https://doi.org/10.1007/s00134-018-5078-z.
Article
PubMed
Google Scholar
Banares R, Nevens F, Larsen FS, Jalan R, Albillos A, Dollinger M, et al. Extracorporeal albumin dialysis with the molecular adsorbent recirculating system in acute-on-chronic liver failure: the RELIEF trial. Hepatology. 2013;57:1153–62. https://doi.org/10.1002/hep.26185.
Article
CAS
PubMed
Google Scholar
Kribben A, Gerken G, Haag S, Herget-Rosenthal S, Treichel U, Betz C, et al. Effects of fractionated plasma separation and adsorption on survival in patients with acute-on-chronic liver failure. Gastroenterology. 2012;142(782–789):e3. https://doi.org/10.1053/j.gastro.2011.12.056.
Article
CAS
Google Scholar
Shen Y, Wang X-L, Wang B, Shao J-G, Liu Y-M, Qin Y, et al. Survival benefits with artificial liver support system for acute-on-chronic liver failure: a time series-based meta-analysis. Medicine (Baltimore). 2016;95:e2506. https://doi.org/10.1097/MD.0000000000002506.
Article
PubMed
PubMed Central
Google Scholar
Brochard L, Abroug F, Brenner M, Broccard AF, Danner RL, Ferrer M, et al. An Official ATS/ERS/ESICM/SCCM/SRLF Statement: prevention and Management of Acute Renal Failure in the ICU Patient: an international consensus conference in intensive care medicine. Am J Respir Crit Care Med. 2010;181:1128–55. https://doi.org/10.1164/rccm.200711-1664ST.
Article
PubMed
Google Scholar
EASL clinical practice guidelines on the management of ascites, spontaneous bacterial peritonitis, and hepatorenal syndrome in cirrhosis. J Hepatol. 2010;53:397–417. https://doi.org/10.1016/j.jhep.2010.05.004.
Sarin SK, Kedarisetty CK, Abbas Z, Amarapurkar D, Bihari C, Chan AC, et al. Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific Association for the Study of the Liver (APASL) 2014. Hepatol Int. 2014;8:453–71. https://doi.org/10.1007/s12072-014-9580-2.
Article
PubMed
Google Scholar
Ronco C, Bellomo R. Acute renal failure and multiple organ dysfunction in the ICU: from renal replacement therapy (RRT) to multiple organ support therapy (MOST). Int J Artif Organs. 2002;25:733–47.
Article
CAS
Google Scholar
Ranieri VM, Brodie D, Vincent J-L. Extracorporeal organ support: from technological tool to clinical strategy supporting severe organ failure. JAMA. 2017;318:1105–6. https://doi.org/10.1001/jama.2017.10108.
Article
PubMed
Google Scholar
Yamasaki K, Maruyama T, Yoshimoto K, Tsutsumi Y, Narazaki R, Fukuhara A, et al. Interactive binding to the two principal ligand binding sites of human serum albumin: effect of the neutral-to-base transition. Biochim Biophys Acta. 1999;1432:313–23.
Article
CAS
Google Scholar
de Garibay A, Kellum JA, Honigschnabel J, Kreymann B. Respiratory and metabolic acidosis correction with the ADVanced Organ Support system. Intensive Care Med Exp. 2019;7:56. https://doi.org/10.1186/s40635-019-0269-7.
Article
Google Scholar
Al-Chalabi A, Matevossian E, von Thaden A, Schreiber C, Radermacher P, Huber W, et al. Evaluation of an ADVanced Organ Support (ADVOS) system in a two-hit porcine model of liver failure plus endotoxemia. Intensive Care Med Exp. 2017;5:31. https://doi.org/10.1186/s40635-017-0144-3.
Article
PubMed
PubMed Central
Google Scholar
Al-Chalabi A, Matevossian E, Thaden A-K, Luppa P, Neiss A, Schuster T, et al. Evaluation of the Hepa Wash® treatment in pigs with acute liver failure. BMC Gastroenterol. 2013;13:83. https://doi.org/10.1186/1471-230x-13-83.
Article
CAS
PubMed
PubMed Central
Google Scholar
Huber W, Henschel B, Schmid R, Al-Chalabi A. First clinical experience in 14 patients treated with ADVOS: a study on feasibility, safety and efficacy of a new type of albumin dialysis. BMC Gastroenterol. 2017;17:32. https://doi.org/10.1186/s12876-017-0569-x.
Article
PubMed
PubMed Central
Google Scholar
Le Gall JR, Lemeshow S, Saulnier F. A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study. JAMA. 1993;270:2957–63.
Article
Google Scholar
Vincent JL, Moreno R, Takala J, Willatts S, Mendonca A, Bruining H, et al. The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine. Intensive Care Med. 1996;22:707–10.
Article
CAS
Google Scholar
Kellum JA, Lameire N, Aspelin P, Barsoum RS, Burdmann EA, Goldstein SL, et al. Kidney Disease Improving Global Outcomes KDIGO Acute Kidney, Injury Work Group. KDIGO clinical practice guideline for acute kidney injury. Kidney Int Suppl. 2012;2:1–138. https://doi.org/10.1038/kisup.2012.1.
Article
Google Scholar
Wendon J, Cordoba J, Dhawan A, Larsen FS, Manns M, Samuel D, et al. EASL Clinical Practical Guidelines on the management of acute (fulminant) liver failure. J Hepatol. 2017;66:1047–81. https://doi.org/10.1016/j.jhep.2016.12.003.
Article
PubMed
Google Scholar
Fuhrmann V, Kneidinger N, Herkner H, Heinz G, Nikfardjam M, Bojic A, et al. Hypoxic hepatitis: underlying conditions and risk factors for mortality in critically ill patients. Intensive Care Med. 2009;35:1397–405. https://doi.org/10.1007/s00134-009-1508-2.
Article
PubMed
Google Scholar
Fuhrmann V, Kneidinger N, Herkner H, Heinz G, Nikfardjam M, Bojic A, et al. Impact of hypoxic hepatitis on mortality in the intensive care unit. Intensive Care Med. 2011;37:1302–10. https://doi.org/10.1007/s00134-011-2248-7.
Article
PubMed
Google Scholar
Ranieri VM, Rubenfeld GD, Thompson BT, Ferguson ND, Caldwell E, Fan E, et al. Acute respiratory distress syndrome: the Berlin Definition. JAMA. 2012;307:2526–33. https://doi.org/10.1001/jama.2012.5669.
Article
CAS
PubMed
Google Scholar
Bellomo R, Cass A, Cole L, Finfer S, Gallagher M, Lo S, et al. Intensity of continuous renal-replacement therapy in critically ill patients. N Engl J Med. 2009;361:1627–38. https://doi.org/10.1056/NEJMoa0902413.
Article
PubMed
Google Scholar
Zarbock A, Kellum JA, Schmidt C, van Aken H, Wempe C, Pavenstadt H, et al. Effect of early vs delayed initiation of renal replacement therapy on mortality in critically ill patients with acute kidney injury: the ELAIN randomized clinical trial. JAMA. 2016;315:2190–9. https://doi.org/10.1001/jama.2016.5828.
Article
CAS
PubMed
Google Scholar
Jung B, Rimmele T, Le Goff C, Chanques G, Corne P, Jonquet O, et al. Severe metabolic or mixed acidemia on intensive care unit admission: incidence, prognosis and administration of buffer therapy. A prospective, multiple-center study. Crit Care. 2011;15:R238. https://doi.org/10.1186/cc10487.
Article
PubMed
PubMed Central
Google Scholar
Jaber S, Paugam C, Futier E, Lefrant J-Y, Lasocki S, Lescot T, et al. Sodium bicarbonate therapy for patients with severe metabolic acidaemia in the intensive care unit (BICAR-ICU): a multicentre, open-label, randomised controlled, phase 3 trial. Lancet. 2018. https://doi.org/10.1016/S0140-6736(18)31080-8.
Article
PubMed
Google Scholar
Stewart PA. Modern quantitative acid-base chemistry. Can J Physiol Pharmacol. 1983;61:1444–61.
Article
CAS
Google Scholar
Kellum JA, Paul WG, Elbers PWG. Stewart’s textbook of acid-base. 2nd ed. United States of America: Luluom; 2009.
Google Scholar
Figge J, Mydosh T, Fencl V. Serum proteins and acid-base equilibria: a follow-up. J Lab Clin Med. 1992;120:713–9.
CAS
PubMed
Google Scholar
Figge J, Rossing TH, Fencl V. The role of serum proteins in acid-base equilibria. J Lab Clin Med. 1991;117:453–67.
CAS
PubMed
Google Scholar
Dorman PJ, Sullivan WJ, Pitts RF. The renal response to acute respiratory acidosis. J Clin Invest. 1954;33:82–90.
Article
CAS
Google Scholar
Eloot S, van Biesen W, Vanholder R. A sad but forgotten truth: the story of slow-moving solutes in fast hemodialysis. Semin Dial. 2012;25:505–9. https://doi.org/10.1111/j.1525-139X.2012.01107.x.
Article
PubMed
Google Scholar
Basile C, Libutti P, Di Turo AL, Casino FG, Vernaglione L, Tundo S, et al. Removal of uraemic retention solutes in standard bicarbonate haemodialysis and long-hour slow-flow bicarbonate haemodialysis. Nephrol Dial Transplant. 2011;26:1296–303. https://doi.org/10.1093/ndt/gfq543.
Article
CAS
PubMed
Google Scholar
Huber W, Leinfelder M, Lahmer T, Batres-Baires G, Rasch S, Schreiber S, Schmid R. Feasibility of ultrafiltration in patients treated with the ADVOS/HepaWash-device under haemodynamic monitoring with transpulmonary thermodilution (TPTD) and pulse contour analysis (PCA): the HAEMADVOS-III-study: 39th International Symposium on Intensive Care and Emergency Medicine. Crit Care. 2019;23(72):P303.
Google Scholar
Laleman W, Wilmer A, Evenepoel P, Elst IV, Zeegers M, Zaman Z, et al. Effect of the molecular adsorbent recirculating system and prometheus devices on systemic haemodynamics and vasoactive agents in patients with acute-on-chronic alcoholic liver failure. Crit Care. 2006;10:R108. https://doi.org/10.1186/cc4985.
Article
PubMed
PubMed Central
Google Scholar
Schmidt LE, Wang LP, Hansen BA, Larsen FS. Systemic hemodynamic effects of treatment with the molecular adsorbents recirculating system in patients with hyperacute liver failure: a prospective controlled trial. Liver Transpl. 2003;9:290–7. https://doi.org/10.1053/jlts.2003.50051.
Article
PubMed
Google Scholar
Hassanein TI, Tofteng F, Brown RS, McGuire B, Lynch P, Mehta R, et al. Randomized controlled study of extracorporeal albumin dialysis for hepatic encephalopathy in advanced cirrhosis. Hepatology. 2007;46:1853–62. https://doi.org/10.1002/hep.21930.
Article
CAS
PubMed
Google Scholar
Jager B, Drolz A, Michl B, Schellongowski P, Bojic A, Nikfardjam M, et al. Jaundice increases the rate of complications and one-year mortality in patients with hypoxic hepatitis. Hepatology. 2012;56:2297–304. https://doi.org/10.1002/hep.25896.
Article
CAS
PubMed
Google Scholar
Nayak SL, Kumar M, Bihari C, Rastogi A. Bile cast nephropathy in patients with acute kidney injury due to hepatorenal syndrome: a postmortem kidney biopsy study. J Clin Transl Hepatol. 2017;5:92–100. https://doi.org/10.14218/JCTH.2016.00063.
Article
PubMed
PubMed Central
Google Scholar
Foshat M, Ruff HM, Fischer WG, Beach RE, Fowler MR, Ju H, et al. Bile cast nephropathy in cirrhotic patients: effects of chronic hyperbilirubinemia. Am J Clin Pathol. 2017;147:525–35. https://doi.org/10.1093/ajcp/aqx030.
Article
CAS
PubMed
Google Scholar
Brasen JH, Mederacke Y-S, Schmitz J, Diahovets K, Khalifa A, Hartleben B, et al. Cholemic nephropathy causes acute kidney injury and is accompanied by loss of aquaporin 2 in collecting ducts. Hepatology. 2019. https://doi.org/10.1002/hep.30499.
Article
PubMed
Google Scholar
Passos RDH, Caldas JR, Ramos JGR, Batista PBP, Noritomi DT, Akamine N, et al. Acid base variables predict survival early in the course of treatment with continuous venovenous hemodiafiltration. Medicine (Baltimore). 2018;97:e12221. https://doi.org/10.1097/md.0000000000012221.
Article
PubMed
PubMed Central
Google Scholar
Abe H. Role of histidine-related compounds as intracellular proton buffering constituents in vertebrate muscle. Biochemistry (Mosc). 2000;65:757–65.
CAS
PubMed
Google Scholar
Kaneko K, Chuang VTG, Minomo A, Yamasaki K, Bhagavan NV, Maruyama T, Otagiri M. Histidine146 of human serum albumin plays a prominent role at the interface of subdomains IA and IIA in allosteric ligand binding. IUBMB Life. 2011;63:277–85. https://doi.org/10.1002/iub.457.
Article
CAS
PubMed
Google Scholar
Amato MBP, Meade MO, Slutsky AS, Brochard L, Costa ELV, Schoenfeld DA, et al. Driving pressure and survival in the acute respiratory distress syndrome. N Engl J Med. 2015;372:747–55. https://doi.org/10.1056/NEJMsa1410639.
Article
CAS
PubMed
Google Scholar
Raith EP, Udy AA, Bailey M, McGloughlin S, MacIsaac C, Bellomo R, Pilcher DV. Prognostic accuracy of the SOFA score, SIRS criteria, and qSOFA score for in-hospital mortality among adults with suspected infection admitted to the intensive care unit. JAMA. 2017;317:290–300. https://doi.org/10.1001/jama.2016.20328.
Article
PubMed
Google Scholar
Gaudry S, Hajage D, Schortgen F, Martin-Lefevre L, Pons B, Boulet E, et al. Initiation strategies for renal-replacement therapy in the intensive care unit. N Engl J Med. 2016;375:122–33. https://doi.org/10.1056/NEJMoa1603017.
Article
PubMed
Google Scholar