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Table 2 Features of active cancers and association with in-hospital mortality in the study population

From: Clinical spectrum and prognostic impact of cancer in critically ill patients with HIV: a multicentre cohort study

Type and stage of cancer

All patients with active cancer

Alive at hospital discharge

Deceased at hospital discharge

P-value

Solid NADC

Overall (all types pooled)

62

29

33

 

 Lung

22 (35.5)

11 (37.9)

11 (33.3)

0.09

 Intestinal tract

14 (22.6)

4 (13.8)

10 (30.4)

 

 Upper aerodigestive tract

7 (11.3)

6 (20.7)

1 (3.0)

 

 Others

19 (30.6)

8 (27.6)

11 (33.3)

 

 Metastatic

33 (53.2)

14 (48.3)

19 (57.6)

0.81

Stage

 Inaugural admission

30 (48.3)

14 (48.3)

16 (48.5)

0.97

 Response

16 (25.8)

8 (27.6)

8 (24.2)

 

 Relapse

4 (6.5)

2 (6.9)

2 (6.1)

 

 Refractory

12 (19.4)

5 (17.2)

7 (21.2)

 

Haematological NADC

 Overall (all types pooled)

35

24

11

 

 Hodgkin lymphoma

10 (28.6)

6 (25.0)

4 (36.4)

0.50

 Non-AIDS-defining NHL a

11 (31.4)

7 (29.2)

4 (36.4)

 

 Acute leukaemia

9 (25.7)

8 (33.3)

1 (9.1)

 

 Myeloma

5 (14.3)

3 (12.5)

2 (18.2)

 

Stage

 Inaugural admission

21 (60.0)

15 (62.4)

6 (54.5)

0.48

 Response

9 (25.7)

7 (29.2)

2 (18.2)

 

 Relapse

3 (8.6)

1 (4.2)

2 (18.2)

 

 Refractory

2 (5.7)

1 (4.2)

1 (9.1)

 

Solid ADC

 Overall (all types pooled)

20

15

5

NA

 Kaposi sarcoma

19 (95.0)

14 (93.3)

5 (100)

 

 Cervix cancer

1 (5.0)

1 (6.7)

0

 

Haematological ADC

 Overall (all types pooled)

86

59

27

 

 Primary cerebral NHL

4 (4.6)

3 (5.0)

1 (3.7)

0.04

 Burkitt lymphoma

35 (40.7)

29 (49.2)

6 (22.2)

 

 Other AIDS-defining NHL b

47 (54.7)

27 (45.8)

20 (74.1)

 

Stage

 Inaugural admission

65 (75.6)

44 (74.5)

21 (77.8)

0.58

 Response

12 (14.0)

10 (17.0)

2 (7.4)

 

 Relapse

7 (8.1)

4 (6.8)

3 (11.1)

 

 Refractory

2 (2.3)

1 (1.7)

1 (3.7)

 
  1. Variables are exposed as number (percentage)
  2. NADC, non-AIDS-defining cancer; ICU, intensive care unit; NHL, non-Hodgkin lymphoma; ADC, AIDS-defining cancer
  3. aIncluding adult T-cell lymphoma/leukaemia (n = 4), T-cell lymphoma (n = 4), NK-cell lymphoma (n = 1), Waldenström disease (n = 1), and marginal zone lymphoma (n = 1)
  4. bIncluding diffuse large B cell lymphoma (n = 33), plasmablastic lymphoma (n = 10), and primary effusion lymphoma (n = 4)