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  1. Content type: Research

    High-flow oxygen therapy delivered through nasal cannulae improves oxygenation and decreases work of breathing in critically ill patients. Little is known of the physiological effects of high-flow oxygen thera...

    Authors: Tania Stripoli, Savino Spadaro, Rosa Di mussi, Carlo Alberto Volta, Paolo Trerotoli, Francesca De Carlo, Rachele Iannuzziello, Fabio Sechi, Paola Pierucci, Francesco Staffieri, Francesco Bruno, Luigi Camporota and Salvatore Grasso

    Citation: Annals of Intensive Care 2019 9:4

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  2. Content type: Research

    Lung-protective strategies are the cornerstone of mechanical ventilation in critically ill patients with both ARDS and other disorders. Extracorporeal CO2 removal (ECCO2R) may enhance lung protection by allowing ...

    Authors: Jens Nentwich, Dominic Wichmann, Stefan Kluge, Simone Lindau, Haitham Mutlak and Stefan John

    Citation: Annals of Intensive Care 2019 9:3

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  3. Content type: Research

    Although outcomes of critically ill patients with haematological malignancies (HMs) have been fully investigated in terms of organ failure and mortality, data are scarce on health-related quality of life (HRQO...

    Authors: Franck Ehooman, Lucie Biard, Virginie Lemiale, Damien Contou, Nicolas de Prost, Djamel Mokart, Frédéric Pène, Achille Kouatchet, Julien Mayaux, Alexandre Demoule, François Vincent, Martine Nyunga, Fabrice Bruneel, Antoine Rabbat, Christine Lebert, Pierre Perez…

    Citation: Annals of Intensive Care 2019 9:2

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  4. Content type: Research

    During passive mechanical ventilation, the driving pressure of the respiratory system is an important mediator of ventilator-induced lung injury. Monitoring of driving pressure during assisted ventilation, sim...

    Authors: Katerina Vaporidi, Charalambos Psarologakis, Athanasia Proklou, Emmanouil Pediaditis, Evangelia Akoumianaki, Elisavet Koutsiana, Achilleas Chytas, Ioanna Chouvarda, Eumorfia Kondili and Dimitris Georgopoulos

    Citation: Annals of Intensive Care 2019 9:1

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  5. Content type: Research

    Structural neurological complications (ischemic stroke and intracranial bleeding) and their risk factors in patients receiving venoarterial-extracorporeal membrane oxygenation (VA-ECMO) are poorly described. O...

    Authors: Loïc Le Guennec, Clémentine Cholet, Florent Huang, Matthieu Schmidt, Nicolas Bréchot, Guillaume Hékimian, Sébastien Besset, Guillaume Lebreton, Ania Nieszkowska, Pascal Leprince, Alain Combes and Charles-Edouard Luyt

    Citation: Annals of Intensive Care 2018 8:129

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  6. Content type: Research

    There is an absence of controlled clinical data showing bronchodilation effectiveness after nebulization via nasal high-flow therapy circuits.

    Authors: François Reminiac, Laurent Vecellio, Laetitia Bodet-Contentin, Valérie Gissot, Deborah Le Pennec, Charlotte Salmon Gandonnière, Maria Cabrera, Pierre-François Dequin, Laurent Plantier and Stephan Ehrmann

    Citation: Annals of Intensive Care 2018 8:128

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  7. Content type: Research

    Transient and persistent acute kidney injury (AKI) could share similar physiopathological mechanisms. The objective of our study was to assess prognostic impact of AKI duration on ICU mortality.

    Authors: A. S. Truche, S. Perinel Ragey, B. Souweine, S. Bailly, L. Zafrani, L. Bouadma, C. Clec’h, M. Garrouste-Orgeas, G. Lacave, C. Schwebel, F. Guebre-Egziabher, C. Adrie, A. S. Dumenil, Ph. Zaoui, L. Argaud, S. Jamali…

    Citation: Annals of Intensive Care 2018 8:127

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  8. Content type: Research

    The clinical interest of using bubble humidification of oxygen remains controversial. This study was designed to further explore whether delivering dry oxygen instead of bubble-moistened oxygen had an impact o...

    Authors: Laurent Poiroux, Lise Piquilloud, Valérie Seegers, Cyril Le Roy, Karine Colonval, Carole Agasse, Vanessa Zinzoni, Vanessa Hodebert, Alexandre Cambonie, Josselin Saletes, Irma Bourgeon, François Beloncle and Alain Mercat

    Citation: Annals of Intensive Care 2018 8:126

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  9. Content type: Research

    To examine the relationship between delta mean arterial pressure (ΔMAP; MAP change between pre-admission minus post-resuscitation) and acute kidney injury (AKI) among patients with septic shock. In this retros...

    Authors: Rajat N. Moman, Stuart A. Ostby, Abbasali Akhoundi, Rahul Kashyap and Kianoush Kashani

    Citation: Annals of Intensive Care 2018 8:124

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  10. Content type: Research

    Proportional modes (proportional assist ventilation, PAV, and neurally adjusted ventilatory assist, NAVA) could improve patient–ventilator interaction and consequently may be efficient as a weaning mode. The p...

    Authors: Jun Kataoka, Akira Kuriyama, Yasuhiro Norisue and Shigeki Fujitani

    Citation: Annals of Intensive Care 2018 8:123

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  11. Content type: Research

    The administration of endovenous immunoglobulins in patients with septic shock could be beneficial and preparations enriched with IgA and IgM (ivIgGAM) seem to be more effective than those containing only IgG....

    Authors: Giorgio Berlot, Michele Claudio Vassallo, Nicola Busetto, Margarita Nieto Yabar, Tatiana Istrati, Silvia Baronio, Giada Quarantotto, Mattia Bixio, Giulia Barbati, Roberto Dattola, Irene Longo, Antonino Chillemi, Alice Scamperle, Fulvio Iscra and Ariella Tomasini

    Citation: Annals of Intensive Care 2018 8:122

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    The Correction to this article has been published in Annals of Intensive Care 2019 9:33

  12. Content type: Research

    Septic shock is a leading cause of death in critical patients. In patients with gram-negative septic shock, hemoperfusion with polymyxin B aims to remove endotoxins from plasma. We analyzed the clinical and bi...

    Authors: Ana Navas, Ricard Ferrer, Maria Luisa Martínez, Gemma Gomà, Gisela Gili, Jordi Masip, David Suárez and Antonio Artigas

    Citation: Annals of Intensive Care 2018 8:121

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  13. Content type: Research

    Hemodynamic response to prone position (PP) has never been studied in a large series of patients with acute respiratory distress syndrome (ARDS). The primary aim of this study was to estimate the rate of PP se...

    Authors: Martin Ruste, Laurent Bitker, Hodane Yonis, Zakaria Riad, Aurore Louf-Durier, Floriane Lissonde, Sophie Perinel-Ragey, Claude Guerin and Jean-Christophe Richard

    Citation: Annals of Intensive Care 2018 8:120

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  14. Content type: Research

    Acute respiratory distress syndrome (ARDS) patients may present impaired in lung function and structure after hospital discharge that may be related to mechanical ventilation strategy. The aim of this study wa...

    Authors: Carlos Toufen Junior, Roberta R. De Santis Santiago, Adriana S. Hirota, Alysson Roncally S. Carvalho, Susimeire Gomes, Marcelo Brito Passos Amato and Carlos Roberto Ribeiro Carvalho

    Citation: Annals of Intensive Care 2018 8:119

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  15. Content type: Research

    Septic shock has been found to disrupt circadian rhythms. Moreover, timing of onset has been associated with different circadian profiles in experimental studies.

    Authors: Eleni N. Sertaridou, Ioanna G. Chouvarda, Konstantinos I. Arvanitidis, Eirini K. Filidou, George C. Kolios, Ioannis N. Pnevmatikos and Vasilios E. Papaioannou

    Citation: Annals of Intensive Care 2018 8:118

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  16. Content type: Research

    Although the WIND (Weaning according to a New Definition) classification based on duration of ventilation after the first separation attempt has been proposed, this new classification has not been tested in cl...

    Authors: Byeong-Ho Jeong, Kyeong Yoon Lee, Jimyoung Nam, Myeong Gyun Ko, Soo Jin Na, Gee Young Suh and Kyeongman Jeon

    Citation: Annals of Intensive Care 2018 8:115

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  17. Content type: Review

    There is currently no international recommendation for the admission or treatment of the critically ill older patients over 80 years of age in the intensive care unit (ICU), and there is no valid prognostic se...

    Authors: Bertrand Guidet, Helene Vallet, Jacques Boddaert, Dylan W. de Lange, Alessandro Morandi, Guillaume Leblanc, Antonio Artigas and Hans Flaatten

    Citation: Annals of Intensive Care 2018 8:114

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  18. Content type: Research

    Treatment of multiple organ failure frequently requires enhanced hemodynamic monitoring. When renal replacement is indicated, it remains unclear whether transpulmonary thermodilution (TPTD) measurements are in...

    Authors: Stefanie Geith, Lynne Stecher, Christian Rabe, Stefan Sack and Florian Eyer

    Citation: Annals of Intensive Care 2018 8:113

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  19. Content type: Research

    Vasoactive medications are essential in septic shock, but are not fully incorporated into current mortality prediction risk scores. We sought to develop a novel mortality prediction model for septic shock inco...

    Authors: Saraschandra Vallabhajosyula, Jacob C. Jentzer, Aditya A. Kotecha, Dennis H. Murphree Jr., Erin F. Barreto, Ashish K. Khanna and Vivek N. Iyer

    Citation: Annals of Intensive Care 2018 8:112

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  20. Content type: Research

    Sepsis is associated with a deflection of inflammatory and coagulative parameters, since some clotting factors are known to be involved in the host’s defense against infection and inflammation. These parameter...

    Authors: Christian Niederwanger, Mirjam Bachler, Tobias Hell, Caroline Linhart, Andreas Entenmann, Agnes Balog, Katharina Auer and Petra Innerhofer

    Citation: Annals of Intensive Care 2018 8:111

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  21. Content type: Research

    Percutaneous dilatational tracheotomy (PDT) may lead to transient impairment of pulmonary function due to suboptimal ventilation, loss of positive end-expiratory pressure (PEEP) and repetitive suction maneuver...

    Authors: Lars Eichler, Jakob Mueller, Jörn Grensemann, Inez Frerichs, Christian Zöllner and Stefan Kluge

    Citation: Annals of Intensive Care 2018 8:110

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  22. Content type: Research

    A higher chance of survival is a key justification for admission to the intensive care unit (ICU). This implies that physicians should be able to accurately estimate a patient’s prognosis, whether cared for on...

    Authors: Monica Escher, Bara Ricou, Mathieu Nendaz, Fabienne Scherer, Stéphane Cullati, Patricia Hudelson and Thomas Perneger

    Citation: Annals of Intensive Care 2018 8:108

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    The Letter to the Editor to this article has been published in Annals of Intensive Care 2019 9:14

  23. Content type: Research

    Maintenance of mean arterial pressure (MAP) at levels sufficient to avoid tissue hypoperfusion is a key tenet in the management of distributive shock. We hypothesized that patients with distributive shock some...

    Authors: Jean-Louis Vincent, Nathan D. Nielsen, Nathan I. Shapiro, Margaret E. Gerbasi, Aaron Grossman, Robin Doroff, Feng Zeng, Paul J. Young and James A. Russell

    Citation: Annals of Intensive Care 2018 8:107

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    The Letter to the Editor to this article has been published in Annals of Intensive Care 2018 8:116

  24. Content type: Correction

    In the original article [1], the authors noticed a typographical error in Figure 2. The top left box should have included “E/A <0.8 and E <50 cm/s”. Please see below the corrected figure.

    Authors: F. Sanfilippo, S. Scolletta, A. Morelli and A. Vieillard-Baron

    Citation: Annals of Intensive Care 2018 8:106

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    The original article was published in Annals of Intensive Care 2018 8:100

  25. Content type: Research

    The aim of the present study was to assess whether paediatric intensive care units (PICUs) in three central European countries comply with guidelines concerning infrastructure provided by the European Society ...

    Authors: Gert Warncke, Florian Hoffmann, Michael Sasse, Georg Singer, Istvan Szilagyi, Holger Till and Christoph Castellani

    Citation: Annals of Intensive Care 2018 8:105

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  26. Content type: Research

    The French Society of Anaesthesia and Intensive Care Medicine and the French Society of Intensive Care edited guidelines focused on hospital-acquired pneumonia (HAP) in intensive care unit. The goal of 16 Fren...

    Authors: Marc Leone, Lila Bouadma, Bélaïd Bouhemad, Olivier Brissaud, Stéphane Dauger, Sébastien Gibot, Sami Hraiech, Boris Jung, Eric Kipnis, Yoann Launey, Charles-Edouard Luyt, Dimitri Margetis, Fabrice Michel, Djamel Mokart, Philippe Montravers, Antoine Monsel…

    Citation: Annals of Intensive Care 2018 8:104

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  27. Content type: Research

    Pleural effusion is common during invasive mechanical ventilation, but its role during weaning is unclear. We aimed at assessing the prevalence and risk factors for pleural effusion at initiation of weaning. W...

    Authors: Keyvan Razazi, Florence Boissier, Mathilde Neuville, Sébastien Jochmans, Martial Tchir, Faten May, Nicolas de Prost, Christian Brun-Buisson, Guillaume Carteaux and Armand Mekontso Dessap

    Citation: Annals of Intensive Care 2018 8:103

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  28. Content type: Review

    Improving sepsis support is one of the three pillars of a 2017 resolution according to the World Health Organization (WHO). Septic shock is indeed a burden issue in the intensive care units. Hemodynamic stabil...

    Authors: Olivier Lesur, Eugénie Delile, Pierre Asfar and Peter Radermacher

    Citation: Annals of Intensive Care 2018 8:102

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  29. Content type: Research

    Limited data are available regarding prevention of limb ischemia in femorally cannulated patients on venoarterial extracorporeal membrane oxygenation (VA-ECMO). We investigated the association between strategy...

    Authors: Woo Jin Jang, Yang Hyun Cho, Taek Kyu Park, Young Bin Song, Jin-Oh Choi, Joo-Yong Hahn, Seung-Hyuk Choi, Hyeon-Cheol Gwon, Eun-Seok Jeon, Woo Jung Chun, Ju Hyeon Oh and Jeong Hoon Yang

    Citation: Annals of Intensive Care 2018 8:101

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  30. Content type: Review

    There is growing evidence both in the perioperative period and in the field of intensive care (ICU) on the association between left ventricular diastolic dysfunction (LVDD) and worse outcomes in patients. The ...

    Authors: F. Sanfilippo, S. Scolletta, A. Morelli and A. Vieillard-Baron

    Citation: Annals of Intensive Care 2018 8:100

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    The Correction to this article has been published in Annals of Intensive Care 2018 8:106

  31. Content type: Research

    The timing and dose of exclusive nutrition support (ENS) have not been investigated in previous studies aimed at validating the modified Nutrition Risk in Critically Ill (mNUTRIC) score. We therefore evaluated...

    Authors: Charles Chin Han Lew, Gabriel Jun Yung Wong, Ka Po Cheung, Robert J. L. Fraser, Ai Ping Chua, Mary Foong Fong Chong and Michelle Miller

    Citation: Annals of Intensive Care 2018 8:98

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  32. Content type: Research

    Nonosmotic sodium storage has been reported in animals, healthy individuals and patients with hypertension, hyperaldosteronism and end-stage kidney disease. Sodium storage has not been studied in ICU patients,...

    Authors: Lara Hessels, Annemieke Oude Lansink-Hartgring, Miriam Zeillemaker-Hoekstra and Maarten W. Nijsten

    Citation: Annals of Intensive Care 2018 8:97

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  33. Content type: Review

    The effects of perioperative statin therapy on clinical outcome after cardiac or non-cardiac surgery are controversial. We aimed to assess the association between perioperative statin therapy and postoperative...

    Authors: Alessandro Putzu, Carolina Maria Pinto Domingues de Carvalho e Silva, Juliano Pinheiro de Almeida, Alessandro Belletti, Tiziano Cassina, Giovanni Landoni and Ludhmila Abrahao Hajjar

    Citation: Annals of Intensive Care 2018 8:95

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  34. Content type: Research

    Patients with influenza complicated with pneumonia are at high risk of rapid progression to acute respiratory distress syndrome (ARDS). Prone positioning with longer duration and lung-protective strategies mig...

    Authors: Kuo-Chin Kao, Ko-Wei Chang, Ming-Cheng Chan, Shinn-Jye Liang, Ying-Chun Chien, Han-Chung Hu, Li-Chung Chiu, Wei-Chih Chen, Wen-Feng Fang, Yu-Mu Chen, Chau-Chyun Sheu, Ming-Ju Tsai, Wann-Cherng Perng, Chung-Kan Peng, Chieh-Liang Wu, Hao-Chien Wang…

    Citation: Annals of Intensive Care 2018 8:94

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  35. Content type: Review

    The central venous pressure (CVP) is traditionally used as a surrogate of intravascular volume. CVP measurements therefore are often applied at the bedside to guide fluid administration in postoperative and cr...

    Authors: Xiukai Chen, Xiaoting Wang, Patrick M. Honore, Herbert D. Spapen and Dawei Liu

    Citation: Annals of Intensive Care 2018 8:91

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  36. Content type: Research

    Criteria for the Sepsis-3 definition of septic shock include vasopressor treatment to maintain a mean arterial pressure > 65 mmHg and a lactate concentration > 2 mmol/L. The impact of hyperoxia in patients wit...

    Authors: Julien Demiselle, Martin Wepler, Clair Hartmann, Peter Radermacher, Frédérique Schortgen, Ferhat Meziani, Mervyn Singer, Valérie Seegers and Pierre Asfar

    Citation: Annals of Intensive Care 2018 8:90

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  37. Content type: Research

    Closed-loop resuscitation can improve personalization of care, decrease workload and bring expert knowledge in isolated areas. We have developed a new device to control the administration of fluid or simultane...

    Authors: Nicolas Libert, Guillaume Chenegros, Anatole Harrois, Nathalie Baudry, Gilles Cordurie, Ryad Benosman, Eric Vicaut and Jacques Duranteau

    Citation: Annals of Intensive Care 2018 8:89

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  38. Content type: Review

    The streptococcal toxic shock syndrome is a severe complication associated with invasive infections by group A streptococci. In spite of medical progresses in the care of patients with septic shock during the ...

    Authors: Marylin Schmitz, Xavier Roux, Benedikt Huttner and Jérôme Pugin

    Citation: Annals of Intensive Care 2018 8:88

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  39. Content type: Research

    Anti-synthetase (AS) and dermato-pulmonary associated with anti-MDA-5 antibodies (aMDA-5) syndromes are near one of the other autoimmune inflammatory myopathies potentially responsible for severe acute interst...

    Authors: Constance Vuillard, Marc Pineton de Chambrun, Nicolas de Prost, Claude Guérin, Matthieu Schmidt, Auguste Dargent, Jean-Pierre Quenot, Sébastien Préau, Geoffrey Ledoux, Mathilde Neuville, Guillaume Voiriot, Muriel Fartoukh, Rémi Coudroy, Guillaume Dumas, Eric Maury, Nicolas Terzi…

    Citation: Annals of Intensive Care 2018 8:87

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  40. Content type: Research

    In acute respiratory distress syndrome (ARDS) patients, it has recently been proposed to set positive end-expiratory pressure (PEEP) by targeting end-expiratory transpulmonary pressure. This approach, which re...

    Authors: Mehdi Mezidi, Francisco José Parrilla, Hodane Yonis, Zakaria Riad, Stephan H. Böhm, Andreas D. Waldmann, Jean-Christophe Richard, Floriane Lissonde, Romain Tapponnier, Loredana Baboi, Jordi Mancebo and Claude Guérin

    Citation: Annals of Intensive Care 2018 8:86

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  41. Content type: Research

    Noninvasive ventilation (NIV) is the first-line treatment of adult patients with exacerbations of cystic fibrosis (CF). High-flow nasal oxygen therapy (HFNT) might benefit patients with hypoxemia and can reduc...

    Authors: Michael C. Sklar, Martin Dres, Nuttapol Rittayamai, Brent West, Domenico Luca Grieco, Irene Telias, Detajin Junhasavasdikul, Michela Rauseo, Tai Pham, Fabiana Madotto, Carolyn Campbell, Elizabeth Tullis and Laurent Brochard

    Citation: Annals of Intensive Care 2018 8:85

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  42. Content type: Research

    The consequences of the ageing population concerning ICU hospitalisation need to be adequately described. We believe that this discussion should be disease specific. A focus on respiratory infections is of par...

    Authors: Lucile Laporte, Coralie Hermetet, Youenn Jouan, Christophe Gaborit, Emmanuelle Rouve, Kimberly M. Shea, Mustapha Si-Tahar, Pierre-François Dequin, Leslie Grammatico-Guillon and Antoine Guillon

    Citation: Annals of Intensive Care 2018 8:84

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