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  1. Critically ill old intensive care unit (ICU) patients suffering from Sars-CoV-2 disease (COVID-19) are at increased risk for adverse outcomes. This post hoc analysis investigates the association of the Activit...

    Authors: Raphael Romano Bruno, Bernhard Wernly, Hans Flaatten, Jesper Fjølner, Antonio Artigas, Philipp Heinrich Baldia, Stephan Binneboessel, Bernardo Bollen Pinto, Joerg C. Schefold, Georg Wolff, Malte Kelm, Michael Beil, Sigal Sviri, Peter Vernon van Heerden, Wojciech Szczeklik, Muhammed Elhadi…
    Citation: Annals of Intensive Care 2022 12:26
  2. To assess in comatose patients after cardiac arrest (CA) if amplitudes of two somatosensory evoked potentials (SSEP) responses, namely, N20-baseline (N20-b) and N20–P25, are predictive of neurological outcome.

    Authors: Sarah Benghanem, Lee S. Nguyen, Martine Gavaret, Jean-Paul Mira, Frédéric Pène, Julien Charpentier, Angela Marchi and Alain Cariou
    Citation: Annals of Intensive Care 2022 12:25
  3. The clinical impact and outcomes of ventilator-associated pneumonia (VAP) have been scarcely investigated in patients with the acute respiratory distress syndrome (ARDS).

    Authors: Marc Le Pape, Céline Besnard, Camelia Acatrinei, Jérôme Guinard, Maxime Boutrot, Claire Genève, Thierry Boulain and François Barbier
    Citation: Annals of Intensive Care 2022 12:24
  4. Survivors of viral ARDS are at risk of long-term physical, functional and neuropsychological complications resulting from the lung injury itself, but also from potential multiorgan dysfunction, and the long st...

    Authors: Guillaume Eberst, Fréderic Claudé, Lucie Laurent, Aurelia Meurisse, Pauline Roux-Claudé, Cindy Barnig, Dewi Vernerey, Sophie Paget-Bailly, Kevin Bouiller, Catherine Chirouze, Julien Behr, Franck Grillet, Ophélie Ritter, Sinan Karaer, Sébastien Pili-Floury, Hadrien Winiszewski…
    Citation: Annals of Intensive Care 2022 12:23
  5. Respiratory pendelluft phenomenon, defined as intrapulmonary gas redistribution caused by asynchronous alveolar ventilation, could be potentially harmful by inducing lung injury. The aim of the present study w...

    Authors: Yi Chi, Zhanqi Zhao, Inéz Frerichs, Yun Long and Huaiwu He
    Citation: Annals of Intensive Care 2022 12:22
  6. Lymphopenia is a hallmark of severe coronavirus disease 19 (COVID-19). Similar alterations have been described in bacterial sepsis and therapeutic strategies targeting T cell function such as recombinant human...

    Authors: Frank Bidar, Sarah Hamada, Morgane Gossez, Remy Coudereau, Jonathan Lopez, Marie-Angelique Cazalis, Claire Tardiveau, Karen Brengel-Pesce, Marine Mommert, Marielle Buisson, Filippo Conti, Thomas Rimmelé, Anne-Claire Lukaszewicz, Laurent Argaud, Martin Cour, Guillaume Monneret…
    Citation: Annals of Intensive Care 2022 12:21

    The Correction to this article has been published in Annals of Intensive Care 2022 12:30

  7. Intensive care unit (ICU) admissions among older adults are expected to increase, while the benefit remains uncertain. The availability of ICU beds varies between hospitals and between countries and is an impo...

    Authors: Ran Abuhasira, Matthew Anstey, Victor Novack, Somnath Bose, Daniel Talmor and Lior Fuchs
    Citation: Annals of Intensive Care 2022 12:20
  8. Authors: Marco Ferrari, Valentina Quaresima and Felix Scholkmann
    Citation: Annals of Intensive Care 2022 12:19

    The original article was published in Annals of Intensive Care 2022 12:2

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2022 12:18

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2022 12:18

  9. The concept of frailty provides an age-independent, easy-to-use tool for risk stratification. We aimed to summarize the evidence on the efficacy of frailty tools in risk assessment in COVID-19 patients.

    Authors: Máté Rottler, Klementina Ocskay, Zoltán Sipos, Anikó Görbe, Marcell Virág, Péter Hegyi, Tihamér Molnár, Bálint Erőss, Tamás Leiner and Zsolt Molnár
    Citation: Annals of Intensive Care 2022 12:17
  10. To describe health-related quality of life (HRQoL) and dyspnea of COVID-19, 2 and 12 months after an intensive care unit (ICU) stay.

    Authors: Alexandre Demoule, Elise Morawiec, Maxens Decavele, Raphaelle Ohayon, Roxane Malrin, Maria Alejandra Galarza-Jimenez, Pierantonio Laveneziana, Capucine Morelot-Panzini, Thomas Similowski, Yann De Rycke and Jesus Gonzalez-Bermejo
    Citation: Annals of Intensive Care 2022 12:16
  11. Tumor lysis syndrome (TLS) is a life-threatening complication during the treatment of malignant neoplasia. We sought to describe characteristics and predictors of acute kidney injury (AKI), remission and morta...

    Authors: Moustafa Abdel-Nabey, Anis Chaba, Justine Serre, Etienne Lengliné, Elie Azoulay, Michael Darmon and Lara Zafrani
    Citation: Annals of Intensive Care 2022 12:15
  12. Acute kidney injury (AKI) is a common disease in the intensive care unit (ICU). AKI patients with nonrecovery of renal function have a markedly increased risk of death compared with patients with recovery. The...

    Authors: Hui-Miao Jia, Li Cheng, Yi-Bing Weng, Jing-Yi Wang, Xi Zheng, Yi-Jia Jiang, Xin Xin, Shu-Yan Guo, Chao-Dong Chen, Fang-Xing Guo, Yu-Zhen Han, Tian-En Zhang and Wen-Xiong Li
    Citation: Annals of Intensive Care 2022 12:14
  13. A sequential change in body position from supine-to-both lateral positions under constant ventilatory settings could be used as a postural recruitment maneuver in case of acute respiratory distress syndrome (A...

    Authors: Rollin Roldán, Shalim Rodriguez, Fernando Barriga, Mauro Tucci, Marcus Victor, Glasiele Alcala, Renán Villamonte, Fernando Suárez-Sipmann, Marcelo Amato, Laurent Brochard and Gerardo Tusman
    Citation: Annals of Intensive Care 2022 12:13
  14. Acute kidney injury (AKI) is a frequent complication in cardiac arrest survivors and associated with adverse outcome. It remains unclear whether the incidence of AKI increases after the post-cardiac arrest con...

    Authors: Gladys N. Janssens, Joost Daemen, Jorrit S. Lemkes, Eva M. Spoormans, Dieuwertje Janssen, Corstiaan A. den Uil, Lucia S. D. Jewbali, Ton A. C. M. Heestermans, Victor A. W. M. Umans, Frank R. Halfwerk, Albertus Beishuizen, Joris Nas, Judith Bonnes, Peter M. van de Ven, Albert C. van Rossum, Paul W. G. Elbers…
    Citation: Annals of Intensive Care 2022 12:12
  15. To evaluate the association between ventilator type and hospital mortality in patients with acute respiratory distress syndrome (ARDS) related to COVID-19 (SARS-CoV2 infection), a single-center prospective obs...

    Authors: Alexis Ferré, Fabien Marquion, Marc Delord, Antoine Gros, Guillaume Lacave, Virginie Laurent, Sybille Merceron, Marine Paul, Christelle Simon, Gilles Troché, Clément Charbonnel, Stéphanie Marque-Juillet, Fabrice Bruneel and Stéphane Legriel
    Citation: Annals of Intensive Care 2022 12:10
  16. Since the publication of the 2018 Clinical Guidelines about sedation, analgesia, delirium, mobilization, and sleep deprivation in critically ill patients, no evaluation and adequacy assessment of these recomme...

    Authors: Mariana Luz, Bruna Brandão Barreto, Roberta Esteves Vieira de Castro, Jorge Salluh, Felipe Dal-Pizzol, Caio Araujo, Audrey De Jong, Gérald Chanques, Sheila Nainan Myatra, Eduardo Tobar, Carolina Gimenez-Esparza Vich, Federico Carini, Eugene Wesley Ely, Joanna L. Stollings, Kelly Drumright, John Kress…
    Citation: Annals of Intensive Care 2022 12:9
  17. The use of extracorporeal membrane oxygenation (ECMO) in pediatric patients with underlying malignancies remains controversial. However, in an era in which the survival rates for children with malignancies hav...

    Authors: Valerie Slooff, Rianne Hoogendoorn, Jeppe Sylvest Angaard Nielsen, John Pappachan, Angela Amigoni, Fabio Caramelli, Omer Aziz, Enno Wildschut, Sascha Verbruggen, Roman Crazzolara, Christian Dohna-Schwake, Jenny Potratz, Jef Willems, Judit Llevadias, Andrea Moscatelli, Alessia Montaguti…
    Citation: Annals of Intensive Care 2022 12:8
  18. Valproic acid (VPA) poisoning is responsible for life-threatening neurological and metabolic impairments. Despite only low-level evidence of effectiveness, L-carnitine has been used for years to prevent or rev...

    Authors: Philippe Nguyen, Lucie Chevillard, Ahmed S. Gouda, Hervé Gourlain, Laurence Labat, Isabelle Malissin, Nicolas Deye, Sebastian Voicu and Bruno Mégarbane
    Citation: Annals of Intensive Care 2022 12:7
  19. Duration of invasive mechanical ventilation (IMV) prior to extracorporeal membrane oxygenation (ECMO) affects outcome in acute respiratory distress syndrome (ARDS). In coronavirus disease 2019 (COVID-19) relat...

    Authors: Martina Hermann, Daniel Laxar, Christoph Krall, Christina Hafner, Oliver Herzog, Oliver Kimberger, Sebastian Koenig, Felix Kraft, Mathias Maleczek, Klaus Markstaller, Oliver Robak, Bernhard Rössler, Eva Schaden, Peter Schellongowski, Mathias Schneeweiss-Gleixner, Thomas Staudinger…
    Citation: Annals of Intensive Care 2022 12:6
  20. To assess trends in the quality of care for COVID-19 patients at the ICU over the course of time in the Netherlands.

    Authors: Dave A. Dongelmans, Fabian Termorshuizen, Sylvia Brinkman, Ferishta Bakhshi-Raiez, M. Sesmu Arbous, Dylan W. de Lange, Bas C. T. van Bussel and Nicolette F. de Keizer
    Citation: Annals of Intensive Care 2022 12:5
  21. Authors: Nicolas Massart, Virginie Maxime, Pierre Fillatre, Keyvan Razazi, Alexis Ferré, Pierre Moine, Francois Legay, Guillaume Voiriot, Marlene Amara, Francesca Santi, Saad Nseir, Stephanie Marque-Juillet, Rania Bounab, Nicolas Barbarot, Fabrice Bruneel and Charles-Edouard Luyt
    Citation: Annals of Intensive Care 2022 12:4

    The original article was published in Annals of Intensive Care 2021 11:183

  22. The composition of the gut microbiota is highly dynamic and changes according to various conditions. The gut microbiota mainly includes difficult-to-cultivate anaerobic bacteria, hence knowledge about its comp...

    Authors: Piotr Szychowiak, Khanh Villageois-Tran, Juliette Patrier, Jean-François Timsit and Étienne Ruppé
    Citation: Annals of Intensive Care 2022 12:3
  23. Ventilator-associated pneumonia (VAP) causes increased mortality, prolonged hospital stay and increased healthcare costs. Prevention of VAP in intensive care units (ICUs) is currently based on several measures...

    Authors: Pierre Damas, Caroline Legrain, Bernard Lambermont, Nadia Dardenne, Julien Guntz, Grâce Kisoka, Pierre Demaret, Anne-Françoise Rousseau, Laurent Jadot, Sonia Piret, Didier Noirot, Axelle Bertrand, Anne-Françoise Donneau and Benoît Misset
    Citation: Annals of Intensive Care 2022 12:1
  24. Authors: Sebastien Preau, Dominique Vodovar, Boris Jung, Steve Lancel, Lara Zafrani, Aurelien Flatres, Mehdi Oualha, Guillaume Voiriot, Youenn Jouan, Jeremie Joffre, Fabrice Uhel, Nicolas De Prost, Stein Silva, Eric Azabou and Peter Radermacher
    Citation: Annals of Intensive Care 2021 11:185

    The original article was published in Annals of Intensive Care 2021 11:104

  25. There is growing interest towards the use of helmet noninvasive ventilation (NIV) for the management of acute hypoxemic respiratory failure. Gas conditioning through heat and moisture exchangers (HME) or heate...

    Authors: Filippo Bongiovanni, Domenico Luca Grieco, Gian Marco Anzellotti, Luca Salvatore Menga, Teresa Michi, Melania Cesarano, Valeria Raggi, Cecilia De Bartolomeo, Benedetta Mura, Giovanna Mercurio, Sonia D’Arrigo, Giuseppe Bello, Riccardo Maviglia, Mariano Alberto Pennisi and Massimo Antonelli
    Citation: Annals of Intensive Care 2021 11:184
  26. Patients infected with the severe acute respiratory syndrome coronavirus 2 (SARS-COV 2) and requiring intensive care unit (ICU) have a high incidence of hospital-acquired infections; however, data regarding ho...

    Authors: Nicolas Massart, Virginie Maxime, Pierre Fillatre, Keyvan Razazi, Alexis Ferré, Pierre Moine, Francois Legay, Guillaume Voiriot, Marlene Amara, Francesca Santi, Saad Nseir, Stephanie Marque-Juillet, Rania Bounab, Nicolas Barbarot, Fabrice Bruneel and Charles-Edouard Luyt
    Citation: Annals of Intensive Care 2021 11:183

    The Correction to this article has been published in Annals of Intensive Care 2022 12:4

  27. Major therapeutic advances including immunotherapy and targeted therapies have been changing the face of oncology and resulted in improved prognosis as well as in new toxic complications. The aim of this study...

    Authors: Clara Vigneron, Julien Charpentier, Sandrine Valade, Jérôme Alexandre, Samy Chelabi, Lola-Jade Palmieri, Nathalie Franck, Valérie Laurence, Jean-Paul Mira, Matthieu Jamme and Frédéric Pène
    Citation: Annals of Intensive Care 2021 11:182
  28. Since 2019, European guidelines recommend considering extracorporeal life support as salvage strategy for the treatment of acute high-risk pulmonary embolism (PE) with circulatory collapse or cardiac arrest. H...

    Authors: Andrea Stadlbauer, Alois Philipp, Sebastian Blecha, Matthias Lubnow, Dirk Lunz, Jing Li, Armando Terrazas, Christof Schmid, Tobias J. Lange and Daniele Camboni
    Citation: Annals of Intensive Care 2021 11:181
  29. Stratifying patients with sepsis was the basis of the predisposition, infection, response and organ dysfunction (PIRO) concept, an attempt to resolve the heterogeneity in treatment response. The purpose of thi...

    Authors: T. Cardoso, P. P. Rodrigues, C. Nunes, M. Almeida, J. Cancela, F. Rosa, N. Rocha-Pereira, I. Ferreira, F. Seabra-Pereira, P. Vaz, L. Carneiro, C. Andrade, J. Davis, A. Marçal and N. D. Friedman
    Citation: Annals of Intensive Care 2021 11:180
  30. The use of awake prone position concomitant to non-invasive mechanical ventilation in acute respiratory distress syndrome (ARDS) secondary to COVID-19 has shown to improve gas exchange, whereas its effect on t...

    Authors: Davide Chiumello, Elena Chiodaroli, Silvia Coppola, Simone Cappio Borlino, Claudia Granata, Matteo Pitimada and Pedro David Wendel Garcia
    Citation: Annals of Intensive Care 2021 11:179
  31. Cardiac surgery is performed worldwide, and acute kidney injury (AKI) following cardiac surgery is a risk factor for mortality. However, the optimal blood pressure target to prevent AKI after cardiac surgery r...

    Authors: Yuki Kotani, Takuo Yoshida, Junji Kumasawa, Jun Kamei, Akihisa Taguchi, Koji Kido, Naoki Yamaguchi, Takayuki Kariya, Masato Nakasone, Noriko Mikami, Takahiro Koga, Izumi Nakayama, Mami Shibata, Tomonao Yoshida, Hiroshi Nashiki, Shinsuke Karatsu…
    Citation: Annals of Intensive Care 2021 11:178
  32. Dyspnea is common and often severe symptom in mechanically ventilated patients. Proportional assist ventilation (PAV) is an assist ventilatory mode that adjusts the level of assistance to the activity of respi...

    Authors: Côme Bureau, Maxens Decavèle, Sébastien Campion, Marie-Cécile Nierat, Julien Mayaux, Elise Morawiec, Mathieu Raux, Thomas Similowski and Alexandre Demoule
    Citation: Annals of Intensive Care 2021 11:177
  33. Fluid management in patients after subarachnoid hemorrhage (SAH) aims at the optimization of cerebral blood flow and brain oxygenation. In this study, we investigated the effects of hemodynamic management on b...

    Authors: Verena Rass, Elisa Gouvea Bogossian, Bogdan-Andrei Ianosi, Lorenzo Peluso, Mario Kofler, Anna Lindner, Alois J. Schiefecker, Lauma Putnina, Max Gaasch, Werner O. Hackl, Ronny Beer, Bettina Pfausler, Fabio Silvio Taccone and Raimund Helbok
    Citation: Annals of Intensive Care 2021 11:176
  34. The concomitant occurrence of the symptoms intravascular hypovolemia, peripheral edema and hemodynamic instability is typically named Capillary Leak Syndrome (CLS) and often occurs in surgical critical ill pat...

    Authors: Jakob Wollborn, Lars O. Hassenzahl, Daniel Reker, Hans Felix Staehle, Anne Marie Omlor, Wolfgang Baar, Kai B. Kaufmann, Felix Ulbrich, Christian Wunder, Stefan Utzolino, Hartmut Buerkle, Johannes Kalbhenn, Sebastian Heinrich and Ulrich Goebel
    Citation: Annals of Intensive Care 2021 11:175

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2022 12:27

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2022 12:28

  35. Hemodynamic instability is a frequent complication of sustained low-efficiency dialysis (SLED) treatments in the ICU. Intravenous hyperoncotic albumin may prevent hypotension and facilitate ultrafiltration. In...

    Authors: Edward G. Clark, Lauralyn McIntyre, Irene Watpool, Jennifer W. Y. Kong, Tim Ramsay, Elham Sabri, Mark Canney, Gregory L. Hundemer, Pierre-Antoine Brown, Manish M. Sood and Swapnil Hiremath
    Citation: Annals of Intensive Care 2021 11:174
  36. Authors: Surat Tongyoo, Porntipa Tantibundit, Kiattichai Daorattanachai, Tanuwong Viarasilpa, Chairat Permpikul and Suthipol Udompanturak
    Citation: Annals of Intensive Care 2021 11:173

    The original article was published in Annals of Intensive Care 2021 11:172

    The Research to this article has been published in Annals of Intensive Care 2021 11:135

  37. Authors: Radhouane Toumi, Khaoula Meddeb and Mohamed Boussarsar
    Citation: Annals of Intensive Care 2021 11:172

    The original article was published in Annals of Intensive Care 2021 11:135

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2021 11:173

  38. Only a few studies have reported the association between age and mortality in COVID-19 patients who require invasive mechanical ventilation (IMV). We aimed to evaluate the effect of age on COVID-19-related mor...

    Authors: Chie Tanaka, Takashi Tagami, Fumihiko Nakayama, Saori Kudo, Akiko Takehara, Reo Fukuda, Junya Kaneko, Yoshito Ishiki, Shin Sato, Ami Shibata, Masamune Kuno, Kyoko Unemoto, Masayuki Hojo, Tetsuya Mizoue, Yusuke Asai, Setsuko Suzuki…
    Citation: Annals of Intensive Care 2021 11:171
  39. Predicting outcomes of critically ill intensive care unit (ICU) patients with coronavirus-19 disease (COVID-19) is a major challenge to avoid futile, and prolonged ICU stays.

    Authors: Matthieu Schmidt, Bertrand Guidet, Alexandre Demoule, Maharajah Ponnaiah, Muriel Fartoukh, Louis Puybasset, Alain Combes and David Hajage
    Citation: Annals of Intensive Care 2021 11:170
  40. The coronavirus disease 2019 (COVID-19) pandemic has significantly influenced epidemiology, yet its impact on out-of-hospital cardiac arrest (OHCA) remains unclear. We aimed to evaluate the impact of the pande...

    Authors: Seth En Teoh, Yoshio Masuda, Darren Jun Hao Tan, Nan Liu, Laurie J. Morrison, Marcus Eng Hock Ong, Audrey L. Blewer and Andrew Fu Wah Ho
    Citation: Annals of Intensive Care 2021 11:169
  41. Atrial fibrillation (AF) is the most documented arrhythmia in COVID-19 pneumonia. Left atrial (LA) strain (LAS) analysis, a marker of LA contractility, have been associated with the development of AF in severa...

    Authors: Christophe Beyls, Alexis Hermida, Yohann Bohbot, Nicolas Martin, Christophe Viart, Solenne Boisgard, Camille Daumin, Pierre Huette, Hervé Dupont, Osama Abou-Arab and Yazine Mahjoub
    Citation: Annals of Intensive Care 2021 11:168
  42. Dynamic pulmonary hyperinflation may develop in patients with chronic obstructive pulmonary disease (COPD) due to dynamic airway collapse and/or increased airway resistance, increasing the risk of volutrauma a...

    Authors: L. H. Roesthuis, J. G. van der Hoeven, C. Guérin, J. Doorduin and L. M. A. Heunks
    Citation: Annals of Intensive Care 2021 11:167
  43. Among the long-term consequences of sepsis (also termed “post-sepsis syndrome”) the increased risk of unexplained cardiovascular complications, such as myocardial infarction, acute heart failure or stroke, is ...

    Authors: Hamid Merdji, Valérie Schini-Kerth, Ferhat Meziani and Florence Toti
    Citation: Annals of Intensive Care 2021 11:166
  44. Critical care randomized controlled trials (RCTs) are often published in high-impact journals, whether general journals [the New England Journal of Medicine (NEJM), The Lancet, the Journal of the American Medi...

    Authors: Joris Pensier, Audrey De Jong, Gerald Chanques, Emmanuel Futier, Elie Azoulay, Nicolas Molinari and Samir Jaber
    Citation: Annals of Intensive Care 2021 11:165
  45. Optimal flow settings during high-flow nasal cannula (HFNC) therapy are unknown. We investigated the optimal flow settings during HFNC therapy based on breathing pattern and tidal inspiratory flows in patients...

    Authors: Jie Li, J. Brady Scott, James B. Fink, Brooke Reed, Oriol Roca and Rajiv Dhand
    Citation: Annals of Intensive Care 2021 11:164
  46. Ventilator-associated pneumonia (VAP) caused by Stenotrophomonas maltophilia is poorly described in the literature. However, it has been shown to be associated with increased morbidity and mortality. Probabilisti...

    Authors: Bérénice Puech, Clémence Canivet, Laura Teysseyre, Guillaume Miltgen, Thomas Aujoulat, Margot Caron, Chloé Combe, Julien Jabot, Olivier Martinet, Jerome Allyn, Cyril Ferdynus and Nicolas Allou
    Citation: Annals of Intensive Care 2021 11:160

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