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  1. Was it worth it—what is the outcome after the extended ICU (intensive care unit) length of stay for COVID-19 patients? Surprisingly, data on long-term mortality in large cohorts are lacking. We investigate lon...

    Authors: Elsa Hägglöf, Max Bell, Erik Zettersten, Lars Engerström and Emma Larsson
    Citation: Annals of Intensive Care 2023 13:76
  2. The respective benefits of high and low doses of dexamethasone (DXM) in patients with severe acute respiratory syndrome coronavirus 2 (SARS-Cov2) and acute respiratory failure (ARF) are controversial, with two...

    Authors: Sylvie Chevret, Lila Bouadma, Claire Dupuis, Charles Burdet and Jean-François Timsit
    Citation: Annals of Intensive Care 2023 13:75

    The Correction to this article has been published in Annals of Intensive Care 2023 13:95

  3. Both AIDS-defining and non-AIDS-defining cancers (ADC/NADC) predispose people living with HIV (PLHIV) to critical illnesses. The objective of this multicentre study was to investigate the prognostic impact of ...

    Authors: Piotr Szychowiak, Thierry Boulain, Jean-François Timsit, Alexandre Elabbadi, Laurent Argaud, Stephan Ehrmann, Nahema Issa, Emmanuel Canet, Frédéric Martino, Fabrice Bruneel, Jean-Pierre Quenot, Florent Wallet, Élie Azoulay and François Barbier
    Citation: Annals of Intensive Care 2023 13:74

    The Correction to this article has been published in Annals of Intensive Care 2024 14:27

  4. Data about critically ill metastatic cancer patients functional outcome after unplanned admission to the ICU are scarce. The aim of this study was to assess factors associated with 90-day return home and 1-yea...

    Authors: Frédéric Gonzalez, Rémi Starka, Laurent Ducros, Magali Bisbal, Laurent Chow-Chine, Luca Servan, Jean-Manuel de Guibert, Bruno Pastene, Marion Faucher, Antoine Sannini, Marc Leone and Djamel Mokart
    Citation: Annals of Intensive Care 2023 13:73
  5. Pulse pressure variation (PPV) is unreliable in predicting fluid responsiveness (FR) in patients receiving mechanical ventilation with spontaneous breathing activity. Whether PPV can be valuable for predicting...

    Authors: Hui Chen, Meihao Liang, Yuanchao He, Jean-Louis Teboul, Qin Sun, Jianfen Xie, Yi Yang, Haibo Qiu and Ling Liu
    Citation: Annals of Intensive Care 2023 13:72
  6. The scarcity of sepsis epidemiologic data from most low- and middle-income countries (LMICs) hampered estimation of regional and global burden of the disease, and provided limited guidance for policy makers. W...

    Authors: Run Dong, Wei Liu, Li Weng, Peng Yin, Jinmin Peng, Yan Chen, Shan Li, Chunyao Wang, Wei Jiang, Xiaoyun Hu, Bin Du and Maigeng Zhou
    Citation: Annals of Intensive Care 2023 13:71
  7. Patients undergoing cardiac surgery are prone to numerous complications. Increased vascular permeability may be associated with morbidity and mortality due to hemodynamic instability, fluid overload, and edema...

    Authors: Jakob Wollborn, Zilu Zhang, Julie Gaa, Moritz Gentner, Christian Hausmann, Felix Saenger, Karina Weise, Samuel Justice, Jean-Luca Funk, Hans Felix Staehle, Marie Thomas, Raphael R. Bruno, Babak Saravi, Jan O. Friess, Markus Marx, Hartmut Buerkle…
    Citation: Annals of Intensive Care 2023 13:70
  8. Following the results of randomized controlled trials on levosimendan, French health authorities requested an update of the current use and side-effects of this medication on a national scale.

    Authors: Bernard Cholley, Mirela Bojan, Benoit Guillon, Emmanuel Besnier, Mathieu Mattei, Bruno Levy, Alexandre Ouattara, Nadir Tafer, Clément Delmas, David Tonon, Bertrand Rozec, Jean-Luc Fellahi, Pascal Lim, François Labaste, François Roubille, Thibaut Caruba…
    Citation: Annals of Intensive Care 2023 13:69

    The Correction to this article has been published in Annals of Intensive Care 2023 13:94

  9. In this narrative review, we describe the most important age-related “syndromes” found in the old ICU patients. The syndromes are frailty, comorbidity, cognitive decline, malnutrition, sarcopenia, loss of func...

    Authors: Hélène Vallet, Bertrand Guidet, Ariane Boumendil, Dylan W. De Lange, Susannah Leaver, Wojciech Szczeklik, Christian Jung, Sigal Sviri, Michael Beil and Hans Flaatten
    Citation: Annals of Intensive Care 2023 13:68
  10. The ICU (intensive care unit) involves potentially traumatic work for the professionals who work there. This narrative review seeks to identify the prevalence of post-traumatic stress disorder (PTSD) among ICU...

    Authors: Victoire Deltour, Anne-Laure Poujol and Alexandra Laurent
    Citation: Annals of Intensive Care 2023 13:66
  11. Healthcare-associated infections involving Gram-negative bacteria (GNB) with difficult-to-treat resistance (DTR) phenotype are associated with impaired patient-centered outcomes and poses daily therapeutic cha...

    Authors: François Barbier, Sami Hraiech, Solen Kernéis, Nathanaël Veluppillai, Olivier Pajot, Julien Poissy, Damien Roux and Jean-Ralph Zahar
    Citation: Annals of Intensive Care 2023 13:65
  12. High-flow nasal oxygen (HFNO) is increasingly used in patients with acute hypoxemic respiratory failure. It is uncertain whether a broadened Berlin definition of acute respiratory distress syndrome (ARDS), in ...

    Authors: Fleur-Stefanie L. I. M. van der Ven, Christel M. A. Valk, Siebe Blok, Michelle G. Brouwer, Dai Ming Go, Amanda Lokhorst, Pien Swart, David M. P. van Meenen, Frederique Paulus and Marcus J. Schultz
    Citation: Annals of Intensive Care 2023 13:64
  13. Clinical practice of aerosol delivery in conjunction with respiratory support devices for critically ill adult patients remains a topic of controversy due to the complexity of the clinical scenarios and limite...

    Authors: Jie Li, Kai Liu, Shan Lyu, Guoqiang Jing, Bing Dai, Rajiv Dhand, Hui-Ling Lin, Paolo Pelosi, Ariel Berlinski, Jordi Rello, Antoni Torres, Charles-Edouard Luyt, Jean-Bernard Michotte, Qin Lu, Gregory Reychler, Laurent Vecellio…
    Citation: Annals of Intensive Care 2023 13:63
  14. Has either the underlying risk or the mortality incidence among ICU patients receiving mechanical ventilation (MV) in the literature changed in recent decades? Interpreting ICU mortality trends requires an adj...

    Authors: James C. Hurley
    Citation: Annals of Intensive Care 2023 13:62
  15. SARS-CoV-2 virus infection can lead to acute respiratory distress syndrome (ARDS), which can be complicated by severe muscle wasting. Until now, data on muscle loss of critically ill COVID-19 patients are limi...

    Authors: Johannes Kolck, Zvonimir A. Rako, Nick L. Beetz, Timo A. Auer, Laura K. Segger, Christian Pille, Tobias Penzkofer, Uli Fehrenbach and Dominik Geisel
    Citation: Annals of Intensive Care 2023 13:61
  16. To develop and validate classifier models that could be used to identify patients with a high percentage of potentially recruitable lung from readily available clinical data and from single CT scan quantitativ...

    Authors: Francesca Pennati, Andrea Aliverti, Tommaso Pozzi, Simone Gattarello, Fabio Lombardo, Silvia Coppola and Davide Chiumello
    Citation: Annals of Intensive Care 2023 13:60
  17. New beta-lactams, associated or not with beta-lactamase inhibitors (NBs/BIs), can respond to the spread of carbapenemase-producing enterobacteriales and nonfermenting carbapenem-resistant bacteria. The risk of...

    Authors: Pierre-François Dequin, Cécile Aubron, Henri Faure, Denis Garot, Max Guillot, Olfa Hamzaoui, Virginie Lemiale, Julien Maizel, Joy Y. Mootien, David Osman, Marie Simon, Arnaud W. Thille, Christophe Vinsonneau and Khaldoun Kuteifan
    Citation: Annals of Intensive Care 2023 13:59
  18. Inhaled nitric oxide (iNO) has been widely used in patients with COVID-19-related acute respiratory distress syndrome (C-ARDS), though its physiological effects and outcome are debated in this setting. The obj...

    Authors: Armand Mekontso Dessap, Laurent Papazian, Manuella Schaller, Saad Nseir, Bruno Megarbane, Luc Haudebourg, Jean-François Timsit, Jean-Louis Teboul, Khaldoun Kuteifan, Marc Gainnier, Michel Slama, Patrick Houeto, Laurent Lecourt, Alain Mercat and Antoine Vieillard-Baron
    Citation: Annals of Intensive Care 2023 13:57
  19. Females and ethnic minorities are underrepresented in the first and senior authorships positions of academic publications. This stems from various structural and systemic inequalities and discrimination in the...

    Authors: Subhash Chander, Sindhu Luhana, Fnu Sadarat, Lorenzo Leys, Om Parkash and Roopa Kumari
    Citation: Annals of Intensive Care 2023 13:56
  20. COVID-19-associated acute respiratory distress syndrome (ARDS) supported by veno-venous extra-corporal membrane oxygenation (vv-ECMO) results in a high in-hospital mortality rate of more than 35%. However, aft...

    Authors: Simon Valentin, Mathieu Amalric, Guillaume Granier, Benjamin Pequignot, Christophe Guervilly, Kevin Duarte, Nicolas Girerd, Bruno Levy, Paul Dunand, Matthieu Koszutski, Hadrien Roze and Antoine Kimmoun
    Citation: Annals of Intensive Care 2023 13:54
  21. Hyperglycaemia is common in critically ill patients, but blood glucose and insulin management may differ widely among intensive care units (ICUs). We aimed to describe insulin use practices and the resulting g...

    Authors: Maxime Desgrouas, Julien Demiselle, Laure Stiel, Vincent Brunot, Rémy Marnai, Sacha Sarfati, Maud Fiancette, Fabien Lambiotte, Arnaud W. Thille, Maxime Leloup, Sébastien Clerc, Pascal Beuret, Anne-Astrid Bourion, Johan Daum, Rémi Malhomme, Ramin Ravan…
    Citation: Annals of Intensive Care 2023 13:53
  22. Appropriate antibiotic treatment for critically ill patients with serious Gram-negative infections in the intensive care unit is crucial to minimize morbidity and mortality. Several new antibiotics have shown ...

    Authors: Pierluigi Viale, Christian E. Sandrock, Paula Ramirez, Gian Maria Rossolini and Thomas P. Lodise
    Citation: Annals of Intensive Care 2023 13:52
  23. Authors: Andrea Crosignani, Stefano Spina, Francesco Marrazzo, Stefania Cimbanassi, Manu L. N. G. Malbrain, Niels Van Regenmortel, Roberto Fumagalli and Thomas Langer
    Citation: Annals of Intensive Care 2023 13:51

    The original article was published in Annals of Intensive Care 2022 12:98

  24. Out-of-hospital cardiac arrest (OHCA) is a common cause of death. Early circulatory failure is the most common reason for death within the first 48 h. This study in intensive care unit (ICU) patients with OHCA...

    Authors: Yannick Binois, Marie Renaudier, Florence Dumas, Younès Youssfi, Frankie Beganton, Daniel Jost, Lionel Lamhaut, Eloi Marijon, Xavier Jouven, Alain Cariou and Wulfran Bougouin
    Citation: Annals of Intensive Care 2023 13:49
  25. Stenotrophomonas maltophilia is a Gram-negative pathogen that most commonly causes hospital-acquired infections that can be extremely challenging to treat, contributing to underrecognized mortality throughout the...

    Authors: Liang Chen, Jie Hua, Shujie Hong, Chenyang Yuan, Ruochen Jing, Xuanyu Luo, Yihong Zhu, Le Le, Ziqi Wang, Xiaoli Sun and Xiaopu He
    Citation: Annals of Intensive Care 2023 13:47
  26. Central venous catheterization (CVC) is a frequent procedure, practiced by intensivists, anesthesiologists and advanced practice nurses in intensive care units and operative rooms. To reduce CVC-associated mor...

    Authors: Nicolas Boulet, Laurent Muller, Claire M Rickard, Jean-Yves Lefrant and Claire Roger
    Citation: Annals of Intensive Care 2023 13:46

    The Correction to this article has been published in Annals of Intensive Care 2023 13:117

  27. The implantation of venovenous extracorporeal membrane oxygenation (VV-ECMO) support to manage severe acute respiratory distress syndrome generates large variations in carbon dioxide partial pressure (PaCO2) that...

    Authors: Paul Masi, François Bagate, Samuel Tuffet, Mariantonietta Piscitelli, Thierry Folliguet, Keyvan Razazi, Nicolas De Prost, Guillaume Carteaux and Armand Mekontso Dessap
    Citation: Annals of Intensive Care 2023 13:45
  28. Patients with severe acute kidney injury (AKI) who require continuous venovenous hemodiafiltration (CVVHDF) in intensive care unit (ICU) are at high mortality risk. Little is known about clinical biomarkers fo...

    Authors: Yohei Komaru, Moe Oguchi, Tomohito Sadahiro, Taka-aki Nakada, Noriyuki Hattori, Takeshi Moriguchi, Junko Goto, Hidetoshi Shiga, Yoshihiko Kikuchi, Shigeo Negi, Takashi Shigematsu, Naohide Kuriyama, Tomoyuki Nakamura and Kent Doi
    Citation: Annals of Intensive Care 2023 13:42
  29. To develop evidence-based clinical practice guidelines on venous thromboembolism (VTE) prevention in adults with trauma in inpatient settings.

    Authors: Marwa Amer, Mohammed S. Alshahrani, Yaseen M. Arabi, Ahmed Al-jedai, Hassan M. Alshaqaq, Abdulaziz Al-Sharydah, Faisal A. Al-Suwaidan, Hosam Aljehani, Thamer Nouh, Hassan Mashbari, Nehal Tarazan, Saad Alqahtani, Wail Tashkandi, Khalid Maghrabi, Muneerah Albugami, Samaher Hashim…
    Citation: Annals of Intensive Care 2023 13:41
  30. Limiting life-sustaining treatment (LST) in the intensive care unit (ICU) by withholding or withdrawing interventional therapies is considered appropriate if there is no expectation of beneficial outcome. Prog...

    Authors: Oded Mousai, Lola Tafoureau, Tamar Yovell, Hans Flaatten, Bertrand Guidet, Michael Beil, Dylan de Lange, Susannah Leaver, Wojciech Szczeklik, Jesper Fjolner, Akiva Nachshon, Peter Vernon van Heerden, Leo Joskowicz, Christian Jung, Gal Hyams and Sigal Sviri
    Citation: Annals of Intensive Care 2023 13:40
  31. Antibiotic resistance is a major health problem and will be probably one of the leading causes of deaths in the coming years. One of the most effective ways to fight against resistance is to decrease antibioti...

    Authors: David Mokrani, Juliette Chommeloux, Marc Pineton de Chambrun, Guillaume Hékimian and Charles-Edouard Luyt
    Citation: Annals of Intensive Care 2023 13:39
  32. Cardiogenic shock is usually defined as primary cardiac dysfunction with low cardiac output leading to critical organ hypoperfusion, and tissue hypoxia, resulting in high mortality rate between 40% and 50% des...

    Authors: Hamid Merdji, Bruno Levy, Christian Jung, Can Ince, Martin Siegemund and Ferhat Meziani
    Citation: Annals of Intensive Care 2023 13:38
  33. This large-scale analysis pools individual data about the Clinical Frailty Scale (CFS) to predict outcome in the intensive care unit (ICU).

    Authors: Raphael Romano Bruno, Bernhard Wernly, Sean M. Bagshaw, Mark van den Boogaard, Jai N. Darvall, Lina De Geer, Pablo Ruiz de Gopegui Miguelena, Daren K. Heyland, David Hewitt, Aluko A. Hope, Emilie Langlais, Pascale Le Maguet, Carmel L. Montgomery, Dimitrios Papageorgiou, Philippe Seguin, Wytske W. Geense…
    Citation: Annals of Intensive Care 2023 13:37
  34. The high-quality evidence on managing COVID-19 patients requiring extracorporeal membrane oxygenation (ECMO) support is insufficient. Furthermore, there is little consensus on allocating ECMO resources when sc...

    Authors: Ahmed A. Rabie, Alyaa Elhazmi, Mohamed H. Azzam, Akram Abdelbary, Ahmed Labib, Alain Combes, Bishoy Zakhary, Graeme MacLaren, Ryan P. Barbaro, Giles J. Peek, Marta Velia Antonini, Kiran Shekar, Abdulrahman Al‐Fares, Pranay Oza, Yatin Mehta, Huda Alfoudri…
    Citation: Annals of Intensive Care 2023 13:36
  35. Several studies have indicated that commonly used piperacillin-tazobactam (TZP) and meropenem (MEM) dosing regimens lead to suboptimal plasma concentrations for a range of pharmacokinetic/pharmacodynamic (PK/P...

    Authors: Thomas De Corte, Jarne Verhaeghe, Sofie Dhaese, Sarah Van Vooren, Jerina Boelens, Alain G. Verstraete, Veronique Stove, Femke Ongenae, Liesbet De Bus, Pieter Depuydt, Sofie Van Hoecke and Jan J. De Waele
    Citation: Annals of Intensive Care 2023 13:35
  36. Necrotizing soft tissue infections (NSTIs) are rare life-threatening bacterial infections. Few data are available regarding neutropenic patients with NSTIs. Our objectives were to describe the characteristics ...

    Authors: Romain Arrestier, Anis Chaba, Asma Mabrouki, Clément Saccheri, Emmanuel Canet, Marc Pineton de Chambrun, Annabelle Stoclin, Muriel Picard, Florent Wallet, François Perier, Matthieu Turpin, Laurent Argaud, Maxens Decavèle, Nahéma Issa, Cyril Cadoz, Kada Klouche…
    Citation: Annals of Intensive Care 2023 13:34
  37. Lung ultrasound is a non-invasive tool available at the bedside for the assessment of critically ill patients. The objective of this study was to evaluate the usefulness of lung ultrasound in assessing the sev...

    Authors: Seydina Alioune Beye, Boubacar Diallo, Modibo Keita, Yacouba Cissoko, Khadidia Ouattara, Hammadoun Dicko, Majaliwa Shabani, Amadou Sidibé, Modibo Berthé, Yaya Ibrahim Coulibaly, Nouhoum Diani, Mohamed Keita, Yacouba Toloba, Sounkalo Dao, Veronique Suttels, Youssouf Coulibaly…
    Citation: Annals of Intensive Care 2023 13:33
  38. Nosocomial sepsis is a major healthcare issue, but there are few data on estimates of its attributable mortality. We aimed to estimate attributable mortality fraction (AF) due to nosocomial sepsis.

    Authors: Fernando G. Zampieri, Alexandre B. Cavalcanti, Leandro U. Taniguchi, Thiago C. Lisboa, Ary Serpa-Neto, Luciano C. P. Azevedo, Antonio Paulo Nassar Jr, Tamiris A. Miranda, Samara P. C. Gomes, Meton S. de Alencar Filho, Rodrigo T. Amancio da Silva, Fabio Holanda Lacerda, Viviane Cordeiro Veiga, Airton Leonardo de Oliveira Manoel, Rodrigo S. Biondi, Israel S. Maia…
    Citation: Annals of Intensive Care 2023 13:32
  39. Factors associated with severe COVID-19 and death among young adults are not fully understood, including differences between the sexes. The aim of this study was to identify factors associated with severe COVI...

    Authors: Johanna Kämpe, Olof Bohlin, Martin Jonsson, Robin Hofmann, Jacob Hollenberg, Rebecka Rubenson Wahlin, Per Svensson and Per Nordberg
    Citation: Annals of Intensive Care 2023 13:31
  40. To describe clinical and biological features and the outcomes of patients admitted for histoplasmosis in two intensive care units (ICU) in French Guyana and in the French West Indies (Guadeloupe).

    Authors: Laurent Camous, Arthur Surel, Hatem Kallel, Muriel Nicolas, Frederic Martino, Marc Valette, Alexandre Demoule and Jean-David Pommier
    Citation: Annals of Intensive Care 2023 13:30
  41. Immune checkpoint inhibitors (ICI) have revolutionized the management of cancer. They can induce immune-related adverse events (irAE) leading to intensive care unit (ICU) admission. We aimed to describe irAEs ...

    Authors: Anne-Claire Toffart, Anne-Pascale Meert, Florent Wallet, Aude Gibelin, Olivier Guisset, Frédéric Gonzalez, Amélie Seguin, Achille Kouatchet, Myriam Delaunay, Didier Debieuvre, Boris Duchemann, Gaëlle Rousseau-Bussac, Martine Nyunga, David Grimaldi, Albrice Levrat, Elie Azoulay…
    Citation: Annals of Intensive Care 2023 13:29
  42. Over the past 2 years, SARS-CoV-2 infection has resulted in numerous hospitalizations and deaths worldwide. As young intensivists, we have been at the forefront of the fight against the COVID-19 pandemic and i...

    Authors: Bertrand Hermann, Sarah Benghanem, Youenn Jouan, Antoine Lafarge and Alexandra Beurton
    Citation: Annals of Intensive Care 2023 13:28
  43. Acute distress respiratory syndrome (ARDS) patients with veno-venous extra corporeal membrane oxygenation (ECMO) support are particularly exposed to ECMO-associated infection (ECMO-AI). Unfortunately, data reg...

    Authors: Nicolas Massart, Christophe Camus, Nicolas Nesseler, Pierre Fillâtre, Erwan Flecher, Alexandre Mansour, Jean-Philippe Verhoye, Lucie Le Fevre and Charles-Edouard Luyt
    Citation: Annals of Intensive Care 2023 13:27

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