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Annals of Intensive Care
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  1. Hyperoxemia is common and associated with poor outcome during veno-arterial extracorporeal membrane oxygenation (VA ECMO) support for cardiogenic shock. However, little is known about practical daily managemen...

    Authors: Hadrien Winiszewski, Thibault Vieille, Pierre-Grégoire Guinot, Nicolas Nesseler, Mael Le Berre, Laure Crognier, Anne-Claude Roche, Jean-Luc Fellahi, Nicolas D’Ostrevy, Zied Ltaief, Juliette Didier, Osama Abou Arab, Simon Meslin, Vincent Scherrer, Guillaume Besch, Alexandra Monnier…
    Citation: Annals of Intensive Care 2024 14:56
    Content type: Research Published on:

  2. Sickle cell disease (SCD) is one of the most frequent inherited diseases in the world. Over the last decades, in high-income countries, an important decrease in mortality have been observed due to the improvem...

    Authors: Michaël Levy, Jérôme Naudin, Guillaume Geslain, Arielle Maroni, Bérengère Koehl, Fleur Le Bourgeois, Géraldine Poncelet, Maryline Chomton, Anna Deho, Sébastien Julliand, Stéphane Dauger and Julie Sommet
    Citation: Annals of Intensive Care 2024 14:55
    Content type: Research Published on:

  3. The influence of socioeconomic deprivation on health inequalities is established, but its effect on critically ill patients remains unclear, due to inconsistent definitions in previous studies.

    Authors: Morgan Benaïs, Matthieu Duprey, Laura Federici, Michel Arnaout, Pierre Mora, Marc Amouretti, Irma Bourgeon-Ghittori, Stéphane Gaudry, Pierre Garçon, Danielle Reuter, Guillaume Geri, Bruno Megarbane, Jordane Lebut, Armand Mekontso-Dessap, Jean-Damien Ricard, Daniel da Silva…
    Citation: Annals of Intensive Care 2024 14:54
    Content type: Research Published on:

  4. Left atrial strain (LAS) is a measure of atrial wall deformation during cardiac cycle and reflects atrial contribution to cardiovascular performance. Pathophysiological significance of LAS in critically ill pa...

    Authors: Marta Cicetti, François Bagate, Cristina Lapenta, Ségolène Gendreau, Paul Masi and Armand Mekontso Dessap
    Citation: Annals of Intensive Care 2024 14:53
    Content type: Research Published on:

  5. Fluid accumulation (FA) is known to be associated with acute kidney injury (AKI) during intensive care unit (ICU) stay but data on mid-term renal outcome is scarce. The aim of this study was to investigate the...

    Authors: Debora M. Hofer, Livio Ruzzante, Jan Waskowski, Anna S. Messmer and Carmen A. Pfortmueller
    Citation: Annals of Intensive Care 2024 14:52
    Content type: Research Published on:

  6. Legionnaires’ disease (LD) is a common but under-diagnosed cause of community-acquired pneumonia (CAP), although rapid detection of urine antigen testing (UAT) and advances in molecular testing have improved t...

    Authors: Jordi Rello, Camille Allam, Alfonsina Ruiz-Spinelli and Sophie Jarraud
    Citation: Annals of Intensive Care 2024 14:51
    Content type: Review Published on:

  8. Several studies have validated capillary refill time (CRT) as a marker of tissue hypoperfusion, and recent guidelines recommend CRT monitoring during septic shock resuscitation. Therefore, it is relevant to fu...

    Authors: Glenn Hernández, Emilio Daniel Valenzuela, Eduardo Kattan, Ricardo Castro, Camila Guzmán, Alicia Elzo Kraemer, Nicolás Sarzosa, Leyla Alegría, Roberto Contreras, Vanessa Oviedo, Sebastián Bravo, Dagoberto Soto, Claudia Sáez, Hafid Ait-Oufella, Gustavo Ospina-Tascón and Jan Bakker
    Citation: Annals of Intensive Care 2024 14:49
    Content type: Research Published on:

  11. Premorbid conditions influence the outcome of acutely ill adult patients aged 80 years and over who are admitted to the ICU. The aim of this study was to determine the influence of such premorbid conditions on...

    Authors: Dylan W. de Lange, Ivo W. Soliman, Susannah Leaver, Ariane Boumendil, Lenneke E. M. Haas, Ximena Watson, Carol Boulanger, Wojciech Szczeklik, Antonio Artigas, Alessandro Morandi, Finn Andersen, Christian Jung, Rui Moreno, Sten Walther, Sandra Oeyen, Joerg C. Schefold…
    Citation: Annals of Intensive Care 2024 14:46
    Content type: Research Published on:

  12. Cardiogenic shock (CS) is characterized by low cardiac output and sustained tissue hypoperfusion that may result in end-organ dysfunction and death. CS is associated with high short-term mortality, and its man...

    Authors: Driss Laghlam, Sarah Benghanem, Sofia Ortuno, Nadia Bouabdallaoui, Stephane Manzo-Silberman, Olfa Hamzaoui and Nadia Aissaoui
    Citation: Annals of Intensive Care 2024 14:45
    Content type: Review Published on:

  13. Due to aging population and increasing part of immunocompromised patients, a raise in life-threatening organ damage related to VZV can be expected. Two retrospective studies were already conducted on VZV in IC...

    Authors: Jolan Malherbe, Pierre Godard, Jean-Claude Lacherade, Valentin Coirier, Laurent Argaud, Hervé Hyvernat, Francis Schneider, Julien Charpentier, Florent Wallet, Juliette Pocquet, Gaëtan Plantefeve, Jean-Pierre Quenot, Pierre Bay, Agathe Delbove, Hugues Georges, Tomas Urbina…
    Citation: Annals of Intensive Care 2024 14:44
    Content type: Research Published on:

  14. Reliable predictors of outcomes in venoarterial extracorporeal membrane oxygenation (VA-ECMO) therapy are limited. While elevated lactate levels over time have been linked to outcomes in cardiogenic shock (CS)...

    Authors: Bruno Levy, Nicolas Girerd, Guillaume Baudry, Kevin Duarte, Samuel Cuau, Jan Bakker and Antoine Kimmoun
    Citation: Annals of Intensive Care 2024 14:43
    Content type: Research Published on:

  15. Impaired intestinal barrier function can enable passage of enteric microorganisms into the bloodstream and lead to nosocomial bloodstream infections during critical illness. We aimed to determine the relative ...

    Authors: Meri R. J. Varkila, Diana M. Verboom, Lennie P. G. Derde, Tom van der Poll, Marc J. M. Bonten and Olaf L. Cremer
    Citation: Annals of Intensive Care 2024 14:42
    Content type: Research Published on:

  16. This study aimed to assess a potential organ protective effect of volatile sedation in a scenario of severe inflammation with an early cytokine storm (in particular IL-6 elevation) in patients suffering from C...

    Authors: Beatrice Beck-Schimmer, Erik Schadde, Urs Pietsch, Miodrag Filipovic, Seraina Dübendorfer-Dalbert, Patricia Fodor, Tobias Hübner, Reto Schuepbach, Peter Steiger, Sascha David, Bernard D. Krüger, Thomas A. Neff and Martin Schläpfer
    Citation: Annals of Intensive Care 2024 14:41
    Content type: Research Published on:

    The Correction to this article has been published in Annals of Intensive Care 2024 14:90

  17. Coronavirus disease 2019 (COVID-19)-related acute respiratory distress syndrome (ARDS) is associated with high mortality. Extracorporeal membrane oxygenation (ECMO) has been proposed in this setting, but optim...

    Authors: Matthieu Petit, Misylias Bouaoud, Edouard Jullien, Adrien Joseph, Bruno Evrard, Cyril Charron, Anousone Daulasim, Annick Legras, Maeva Gourraud, Marine Goudelin, Philippe Vignon and Antoine Vieillard-Baron
    Citation: Annals of Intensive Care 2024 14:40
    Content type: Research Published on:

  19. The incidence, causes and impact of diaphragm thickness evolution in veno-arterial extracorporeal membrane oxygenation (VA-ECMO) for cardiogenic shock are unknown.

    Authors: Pierre-Henri Moury, Alexandre Béhouche, Sébastien Bailly, Zoé Durand, Géraldine Dessertaine, Angelina Pollet, Samir Jaber, Samuel Verges and Pierre Albaladejo
    Citation: Annals of Intensive Care 2024 14:38
    Content type: Research Published on:

  21. Bloodstream infections (BSIs) by Gram-negative pathogens play a major role in intensive care patients, both in terms of prevalence and severity, especially if multi-drug resistant pathogens are involved. Early...

    Authors: Matteo Rinaldi, Milo Gatti, Tommaso Tonetti, Domenico Nocera, Simone Ambretti, Andrea Berlingeri, Giacomo Nigrisoli, Elisabetta Pierucci, Antonio Siniscalchi, Federico Pea, Pierluigi Viale and Maddalena Giannella
    Citation: Annals of Intensive Care 2024 14:36
    Content type: Research Published on:

  22. In some cases of patients with out-of-hospital cardiac arrest (OHCA) who underwent extracorporeal cardiopulmonary resuscitation (ECPR), negative pupillary light reflex (PLR) and mydriasis upon hospital arrival...

    Authors: Takuro Hamaguchi, Toru Takiguchi, Tomohisa Seki, Naoki Tominaga, Jun Nakata, Takeshi Yamamoto, Takashi Tagami, Akihiko Inoue, Toru Hifumi, Tetsuya Sakamoto, Yasuhiro Kuroda, Shoji Yokobori and the SAVE-J II study group
    Citation: Annals of Intensive Care 2024 14:35
    Content type: Research Published on:

  24. Ventilator-associated pneumonia (VAP) is the leading nosocomial infection in critical care and is associated with adverse outcomes. When VAP is suspected, starting antibiotic therapy (AT) immediately after pul...

    Authors: Maëlle Martin, Solène Forveille, Jean-Baptiste Lascarrou, Amélie Seguin, Emmanuel Canet, Jérémie Lemarié, Maïté Agbakou, Luc Desmedt, Gauthier Blonz, Olivier Zambon, Stéphane Corvec, Aurélie Le Thuaut and Jean Reignier
    Citation: Annals of Intensive Care 2024 14:33
    Content type: Research Published on:

  25. Characterizing patient–ventilator interaction in critically ill patients is time-consuming and requires trained staff to evaluate the behavior of the ventilated patient.

    Authors: Julia Sauer, Jan Graßhoff, Niklas M. Carbon, Willi M. Koch, Steffen Weber-Carstens and Philipp Rostalski
    Citation: Annals of Intensive Care 2024 14:32
    Content type: Research Published on:

  26. Prolonged intensive care unit (ICU) stay is associated with physical, cognitive, and psychological disabilities. The impact of baseline frailty on long-stay ICU patients remains uncertain. This study aims to i...

    Authors: Hannah Wozniak, Tal Sarah Beckmann, Andre Dos Santos Rocha, Jérôme Pugin, Claudia-Paula Heidegger and Sara Cereghetti
    Citation: Annals of Intensive Care 2024 14:31
    Content type: Research Published on:

  27. The two latest studies on prolonged versus intermittent use of β-lactam antibiotics in patients with sepsis did not reach consistent conclusions, further contributing to the controversy surrounding the effecti...

    Authors: Yang Zhao, Bin Zang and Qian Wang
    Citation: Annals of Intensive Care 2024 14:30
    Content type: Review Published on:

  28. Muscle mass evaluation in ICU is crucial since its loss is related with long term complications, including physical impairment. However, quantifying muscle wasting with available bedside tools (ultrasound and ...

    Authors: Cristian Deana, Jan Gunst, Silvia De Rosa, Michele Umbrello, Matteo Danielis, Daniele Guerino Biasucci, Tommaso Piani, Antonella Cotoia, Alessio Molfino and Luigi Vetrugno
    Citation: Annals of Intensive Care 2024 14:29
    Content type: Research Published on:

  29. Suspected upper gastrointestinal bleeding (SUGIB) is a common issue during ICU stay. In the absence of specific guidelines on the indication and timing of esophagogastroduodenoscopy (EGD), there is substantial...

    Authors: Victor Penaud, Thibault Vieille, Tomas Urbina, Vincent Bonny, Paul Gabarre, Louai Missri, Maxime Gasperment, Jean-Luc Baudel, Nicolas Carbonell, Alexandra Beurton, Sayma Chaibi, Aurélia Retbi, Muriel Fartoukh, Gaël Piton, Bertrand Guidet, Eric Maury…
    Citation: Annals of Intensive Care 2024 14:28
    Content type: Research Published on:

  30. Authors: Piotr Szychowiak, Thierry Boulain, Jean-François Timsit, Alexandre Elabbadi, Laurent Argaud, Stephan Ehrmann, Nahema Issa, Emmanuel Canet, Frédéric Martino, Fabrice Bruneel, Jean-Pierre Quenot, Florent Wallet, Élie Azoulay and François Barbier
    Citation: Annals of Intensive Care 2024 14:27
    Content type: Correction Published on:

    The original article was published in Annals of Intensive Care 2023 13:74

  31. Acute kidney injury (AKI) in intensive care unit (ICU) patients with severe COVID-19 is common (> 50%). A specific inflammatory process has been suggested in the pathogenesis of AKI, which could be improved by...

    Authors: Sébastien Rubin, Arthur Orieux, Mathilde Prezelin-Reydit, Antoine Garric, Yoann Picard, Nouchan Mellati, Lisa Le Gall, Antoine Dewitte, Renaud Prevel, Didier Gruson, Guillaume Louis and Alexandre Boyer
    Citation: Annals of Intensive Care 2024 14:26
    Content type: Research Published on:

  32. Cardiac injury is frequently reported in COVID-19 patients, the right ventricle (RV) is mostly affected. We systematically evaluated the cardiac function and longitudinal changes in severe COVID-19 acute respi...

    Authors: Vasiliki Tsolaki, George E. Zakynthinos, Nikitas Karavidas, Vasileios Vazgiourakis, John Papanikolaou, Kyriaki Parisi, Paris Zygoulis, Demosthenes Makris and Epaminondas Zakynthinos
    Citation: Annals of Intensive Care 2024 14:25
    Content type: Research Published on:

  33. Vaccination helped in reducing mortality and disease severity due to COVID-19. Some patients can develop breakthrough infections. The effect of vaccination in critically ill patients admitted with breakthrough...

    Authors: Amarja Ashok Havaldar and Sumithra Selvam
    Citation: Annals of Intensive Care 2024 14:24
    Content type: Research Published on:

  34. Acetaminophen (ACT) has been studied in septic patients with detectable plasmatic levels of cell-free hemoglobin (Hb), where it demonstrated to inhibit the hemoprotein-mediated lipid peroxidation and oxidative...

    Authors: R. Domizi, E. Damiani, A. Carsetti, L. Graciotti, A. D. Procopio, C. Scorcella, E. Casarotta, P. Giaccaglia, A. Donati and E. Adrario
    Citation: Annals of Intensive Care 2024 14:23
    Content type: Research Published on:

  35. The prevalence of hyperdynamic left ventricular (LV) systolic function in septic patients and its impact on mortality remain controversial. In this systematic review and meta-analysis, we investigated the prev...

    Authors: Ryota Sato, Filippo Sanfilippo, Daisuke Hasegawa, Narut Prasitlumkum, Abhijit Duggal and Siddharth Dugar
    Citation: Annals of Intensive Care 2024 14:22
    Content type: Research Published on:

  36. The benefit–risk balance and optimal timing of surgery for severe infective endocarditis (IE) with ischemic or hemorrhagic strokes is unknown. The study aim was to compare the neurological outcome between pati...

    Authors: Alexandre Gros, Benjamin Seguy, Guillaume Bonnet, Yves-Olivier Guettard, Xavier Pillois, Renaud Prevel, Arthur Orieux, Julien Ternacle, Sebastien Préau, Yoan Lavie-Badie, Elisabeth Coupez, Rémi Coudroy, Delphine Marest, Raphaël P. Martins, Didier Gruson, Thomas Tourdias…
    Citation: Annals of Intensive Care 2024 14:21
    Content type: Research Published on:

  37. Chimeric antigen receptor T-cell (CAR-T) therapy is increasingly used in patients with refractory haematological malignancies but can induce severe adverse events. We aimed to describe the clinical features an...

    Authors: Corentin Le Cacheux, Audrey Couturier, Clara Sortais, Roch Houot, Morgane Péré, Thomas Gastinne, Amélie Seguin, Jean Reignier, Jean-Baptiste Lascarrou, Jean-Marc Tadié, Quentin Quelven and Emmanuel Canet
    Citation: Annals of Intensive Care 2024 14:20
    Content type: Research Published on:

  38. Recent alerts have highlighted an increase in group A streptococcal (GAS) infections since 2022 in Europe and the United States. Streptococcus pyogenes can cause limited skin or mucosal disease, but can also pres...

    Authors: Marijke Peetermans, Veerle Matheeussen, Cedric Moerman, Fréderic De Rydt, Sabine Thieren, Emily Pollet, Michael Casaer, Benjamin De Backer, Rudi De Paep, Yves Debaveye, Lars Desmet, Stefanie Desmet, Els I. M. Duval, Vincent Fraipont, Dieter Geysels, Greet Hermans…
    Citation: Annals of Intensive Care 2024 14:19
    Content type: Research Published on:

  39. Inhaled sedation during invasive mechanical ventilation in patients with acute respiratory distress syndrome (ARDS) has received increasing attention. However, inhaled sedation devices increase dead-space vent...

    Authors: Pierre-Louis Pellet, Neven Stevic, Florian Degivry, Bruno Louis, Laurent Argaud, Claude Guérin and Martin Cour
    Citation: Annals of Intensive Care 2024 14:18
    Content type: Research Published on:

  40. Recent studies identified coronavirus disease 2019 (COVID-19) as a risk factor for invasive pulmonary aspergillosis (IPA) but produced conflicting data on IPA incidence and impact on patient outcomes. We aimed...

    Authors: Luc Desmedt, Matthieu Raymond, Aurélie Le Thuaut, Pierre Asfar, Cédric Darreau, Florian Reizine, Gwenhaël Colin, Johann Auchabie, Julien Lorber, Béatrice La Combe, Pierre Kergoat, Baptiste Hourmant, Agathe Delbove, Aurélien Frérou, Jean Morin, Pierre Yves Ergreteau…
    Citation: Annals of Intensive Care 2024 14:17
    Content type: Research Published on:

  41. Bleeding is the most common complication in out-of-hospital cardiac arrest (OHCA) patients receiving extracorporeal cardiopulmonary resuscitation (ECPR). No studies comprehensively described the incidence rate...

    Authors: Shutaro Isokawa, Toru Hifumi, Keita Hirano, Yu Watanabe, Katsuhiro Horie, Kijong Shin, Kasumi Shirasaki, Masahiro Goto, Akihiko Inoue, Tetsuya Sakamoto, Yasuhiro Kuroda, Shiori Tomita, Norio Otani and The SAVE-J II study group
    Citation: Annals of Intensive Care 2024 14:16
    Content type: Research Published on:

  42. Current guidelines for adult patients with pneumococcal meningitis (PM) recommend initial management in intermediate or intensive care units (ICU), but evidence to support these recommendations is limited. We ...

    Authors: Michael Thy, Claire Dupuis, Arthur Mageau, Bruno Mourvillier, Lila Bouadma, Stéphane Ruckly, Anne Perozziello, Andrey Strukov, Damien Van-Gysel, Etienne de Montmollin, Romain Sonneville and Jean-François Timsit
    Citation: Annals of Intensive Care 2024 14:15
    Content type: Research Published on:

  43. Patients with COVID-19 admitted to intensive care unit (ICU) may have right ventricular (RV) injury. The main goal of this study was to investigate the incidence of RV injury and to describe the patient trajec...

    Authors: Mathieu Jozwiak, Claire Dupuis, Pierre Denormandie, Didac Aurenche Mateu, Jean Louchet, Nathan Heme, Jean-Paul Mira, Denis Doyen and Jean Dellamonica
    Citation: Annals of Intensive Care 2024 14:14
    Content type: Research Published on:

  44. Given the pathophysiology of hypoxemia in patients with Covid-19 acute respiratory failure (ARF), it seemed necessary to evaluate whether ROX index (ratio SpO2/FiO2 to respiratory rate) could accurately predict i...

    Authors: Christophe Girault, Michael Bubenheim, Déborah Boyer, Pierre-Louis Declercq, Guillaume Schnell, Philippe Gouin, Jean-Baptiste Michot, Dorothée Carpentier, Steven Grangé, Gaëtan Béduneau and Fabienne Tamion
    Citation: Annals of Intensive Care 2024 14:13
    Content type: Research Published on:

  45. Left ventricular ejection fraction (LVEF) is inconsistently associated with poor outcomes in patients with sepsis. Newer parameters such as LV longitudinal strain (LVLS), mitral annular plane systolic excursio...

    Authors: Patrik Johansson Blixt, Maxime Nguyen, Bernard Cholley, Fredrik Hammarskjöld, Alois Toiron, Belaid Bouhemad, Shaun Lee, Lina De Geer, Henrik Andersson, Meriam Åström Aneq, Jan Engvall and Michelle S. Chew
    Citation: Annals of Intensive Care 2024 14:12
    Content type: Research Published on:

  46. Previously, we reported a decreased mortality rate among patients with COVID-19 who were admitted at the ICU during the final upsurge of the second wave (February–June 2021) in the Netherlands. We examined whe...

    Authors: Fabian Termorshuizen, Dave A. Dongelmans, Sylvia Brinkman, Ferishta Bakhshi-Raiez, M. Sesmu Arbous, Dylan W. de Lange, Bas C. T. van Bussel and Nicolette F. de Keizer
    Citation: Annals of Intensive Care 2024 14:11
    Content type: Research Published on:

  47. Right ventricular (RV) function is tightly coupled to afterload, yet echocardiographic indices of RV function are frequently assessed in isolation. Normalizing RV function for afterload (RV-PA coupling) using ...

    Authors: Emma Bowcock, Stephen Huang, Rachel Yeo, Deshani Walisundara, Chris F. Duncan, Faraz Pathan, Geoffrey Strange, David Playford and Sam Orde
    Citation: Annals of Intensive Care 2024 14:10
    Content type: Research Published on:

  48. Healthcare expenses are increasing, as is the utilization of laboratory resources. Despite this, between 20% and 40% of requested tests are deemed inappropriate. Improper use of laboratory resources leads to u...

    Authors: Luigi Devis, Emilie Catry, Patrick M. Honore, Alexandre Mansour, Giuseppe Lippi, François Mullier and Mélanie Closset
    Citation: Annals of Intensive Care 2024 14:9
    Content type: Review Published on:
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  • Citation Impact 2023
    Journal Impact Factor: 5.7
    5-year Journal Impact Factor: 6.0
    Source Normalized Impact per Paper (SNIP): 1.749
    SCImago Journal Rank (SJR): 2.061

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    Submission to first editorial decision (median days): 7
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  • ISSN: 2110-5820 (electronic)