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  1. Content type: Review

    Improving sepsis support is one of the three pillars of a 2017 resolution according to the World Health Organization (WHO). Septic shock is indeed a burden issue in the intensive care units. Hemodynamic stabil...

    Authors: Olivier Lesur, Eugénie Delile, Pierre Asfar and Peter Radermacher

    Citation: Annals of Intensive Care 2018 8:102

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  2. Content type: Review

    There is growing evidence both in the perioperative period and in the field of intensive care (ICU) on the association between left ventricular diastolic dysfunction (LVDD) and worse outcomes in patients. The ...

    Authors: F. Sanfilippo, S. Scolletta, A. Morelli and A. Vieillard-Baron

    Citation: Annals of Intensive Care 2018 8:100

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    The Correction to this article has been published in Annals of Intensive Care 2018 8:106

  3. Content type: Research

    The timing and dose of exclusive nutrition support (ENS) have not been investigated in previous studies aimed at validating the modified Nutrition Risk in Critically Ill (mNUTRIC) score. We therefore evaluated...

    Authors: Charles Chin Han Lew, Gabriel Jun Yung Wong, Ka Po Cheung, Robert J. L. Fraser, Ai Ping Chua, Mary Foong Fong Chong and Michelle Miller

    Citation: Annals of Intensive Care 2018 8:98

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  4. Content type: Research

    Nonosmotic sodium storage has been reported in animals, healthy individuals and patients with hypertension, hyperaldosteronism and end-stage kidney disease. Sodium storage has not been studied in ICU patients,...

    Authors: Lara Hessels, Annemieke Oude Lansink-Hartgring, Miriam Zeillemaker-Hoekstra and Maarten W. Nijsten

    Citation: Annals of Intensive Care 2018 8:97

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  5. Content type: Review

    The effects of perioperative statin therapy on clinical outcome after cardiac or non-cardiac surgery are controversial. We aimed to assess the association between perioperative statin therapy and postoperative...

    Authors: Alessandro Putzu, Carolina Maria Pinto Domingues de Carvalho e Silva, Juliano Pinheiro de Almeida, Alessandro Belletti, Tiziano Cassina, Giovanni Landoni and Ludhmila Abrahao Hajjar

    Citation: Annals of Intensive Care 2018 8:95

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  6. Content type: Research

    Patients with influenza complicated with pneumonia are at high risk of rapid progression to acute respiratory distress syndrome (ARDS). Prone positioning with longer duration and lung-protective strategies mig...

    Authors: Kuo-Chin Kao, Ko-Wei Chang, Ming-Cheng Chan, Shinn-Jye Liang, Ying-Chun Chien, Han-Chung Hu, Li-Chung Chiu, Wei-Chih Chen, Wen-Feng Fang, Yu-Mu Chen, Chau-Chyun Sheu, Ming-Ju Tsai, Wann-Cherng Perng, Chung-Kan Peng, Chieh-Liang Wu, Hao-Chien Wang…

    Citation: Annals of Intensive Care 2018 8:94

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  7. Content type: Review

    The central venous pressure (CVP) is traditionally used as a surrogate of intravascular volume. CVP measurements therefore are often applied at the bedside to guide fluid administration in postoperative and cr...

    Authors: Xiukai Chen, Xiaoting Wang, Patrick M. Honore, Herbert D. Spapen and Dawei Liu

    Citation: Annals of Intensive Care 2018 8:91

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  8. Content type: Research

    Criteria for the Sepsis-3 definition of septic shock include vasopressor treatment to maintain a mean arterial pressure > 65 mmHg and a lactate concentration > 2 mmol/L. The impact of hyperoxia in patients wit...

    Authors: Julien Demiselle, Martin Wepler, Clair Hartmann, Peter Radermacher, Frédérique Schortgen, Ferhat Meziani, Mervyn Singer, Valérie Seegers and Pierre Asfar

    Citation: Annals of Intensive Care 2018 8:90

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  9. Content type: Research

    Closed-loop resuscitation can improve personalization of care, decrease workload and bring expert knowledge in isolated areas. We have developed a new device to control the administration of fluid or simultane...

    Authors: Nicolas Libert, Guillaume Chenegros, Anatole Harrois, Nathalie Baudry, Gilles Cordurie, Ryad Benosman, Eric Vicaut and Jacques Duranteau

    Citation: Annals of Intensive Care 2018 8:89

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  10. Content type: Review

    The streptococcal toxic shock syndrome is a severe complication associated with invasive infections by group A streptococci. In spite of medical progresses in the care of patients with septic shock during the ...

    Authors: Marylin Schmitz, Xavier Roux, Benedikt Huttner and Jérôme Pugin

    Citation: Annals of Intensive Care 2018 8:88

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  11. Content type: Research

    Anti-synthetase (AS) and dermato-pulmonary associated with anti-MDA-5 antibodies (aMDA-5) syndromes are near one of the other autoimmune inflammatory myopathies potentially responsible for severe acute interst...

    Authors: Constance Vuillard, Marc Pineton de Chambrun, Nicolas de Prost, Claude Guérin, Matthieu Schmidt, Auguste Dargent, Jean-Pierre Quenot, Sébastien Préau, Geoffrey Ledoux, Mathilde Neuville, Guillaume Voiriot, Muriel Fartoukh, Rémi Coudroy, Guillaume Dumas, Eric Maury, Nicolas Terzi…

    Citation: Annals of Intensive Care 2018 8:87

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  12. Content type: Research

    In acute respiratory distress syndrome (ARDS) patients, it has recently been proposed to set positive end-expiratory pressure (PEEP) by targeting end-expiratory transpulmonary pressure. This approach, which re...

    Authors: Mehdi Mezidi, Francisco José Parrilla, Hodane Yonis, Zakaria Riad, Stephan H. Böhm, Andreas D. Waldmann, Jean-Christophe Richard, Floriane Lissonde, Romain Tapponnier, Loredana Baboi, Jordi Mancebo and Claude Guérin

    Citation: Annals of Intensive Care 2018 8:86

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  13. Content type: Research

    Noninvasive ventilation (NIV) is the first-line treatment of adult patients with exacerbations of cystic fibrosis (CF). High-flow nasal oxygen therapy (HFNT) might benefit patients with hypoxemia and can reduc...

    Authors: Michael C. Sklar, Martin Dres, Nuttapol Rittayamai, Brent West, Domenico Luca Grieco, Irene Telias, Detajin Junhasavasdikul, Michela Rauseo, Tai Pham, Fabiana Madotto, Carolyn Campbell, Elizabeth Tullis and Laurent Brochard

    Citation: Annals of Intensive Care 2018 8:85

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  14. Content type: Research

    The consequences of the ageing population concerning ICU hospitalisation need to be adequately described. We believe that this discussion should be disease specific. A focus on respiratory infections is of par...

    Authors: Lucile Laporte, Coralie Hermetet, Youenn Jouan, Christophe Gaborit, Emmanuelle Rouve, Kimberly M. Shea, Mustapha Si-Tahar, Pierre-François Dequin, Leslie Grammatico-Guillon and Antoine Guillon

    Citation: Annals of Intensive Care 2018 8:84

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  15. Content type: Research

    Recent trials showed that video laryngoscopy (VL) did not yield higher first-attempt tracheal intubation success rate than direct laryngoscopy (DL) and was associated with higher rates of complications. Trache...

    Authors: Moon Seong Baek, MyongJa Han, Jin Won Huh, Chae-Man Lim, Younsuck Koh and Sang-Bum Hong

    Citation: Annals of Intensive Care 2018 8:83

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    The Letter to the Editor to this article has been published in Annals of Intensive Care 2019 9:21

  16. Content type: Research

    Chlamydophila pneumoniae (CP) and Mycoplasma pneumoniae (MP) patients could require intensive care unit (ICU) admission for acute respiratory failure.

    Authors: S. Valade, L. Biard, V. Lemiale, L. Argaud, F. Pène, L. Papazian, F. Bruneel, A. Seguin, A. Kouatchet, J. Oziel, S. Rouleau, N. Bele, K. Razazi, O. Lesieur, F. Boissier, B. Megarbane…

    Citation: Annals of Intensive Care 2018 8:81

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  17. Content type: Research

    Although patients with advanced or metastatic lung cancer have poor prognosis, admission to the ICU for management of life-threatening complications has increased over the years. Patients with newly diagnosed ...

    Authors: C. Barth, M. Soares, A. C. Toffart, J. F. Timsit, G. Burghi, C. Irrazabal, N. Pattison, E. Tobar, B. F. Almeida, U. V. Silva, L. C. Azevedo, A. Rabbat, C. Lamer, A. Parrot, V. C. Souza-Dantas, F. Wallet…

    Citation: Annals of Intensive Care 2018 8:80

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  18. Content type: Research

    Whether the respiratory changes of the inferior vena cava diameter during a deep standardized inspiration can reliably predict fluid responsiveness in spontaneously breathing patients with cardiac arrhythmia i...

    Authors: Perrine Bortolotti, Delphine Colling, Vincent Colas, Benoit Voisin, Florent Dewavrin, Julien Poissy, Patrick Girardie, Maeva Kyheng, Fabienne Saulnier, Raphael Favory and Sebastien Preau

    Citation: Annals of Intensive Care 2018 8:79

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  19. Content type: Research

    Ascites is a major complication of decompensated liver cirrhosis. Intraabdominal hypertension and structural alterations of parenchyma involve decisive changes in hepatosplanchnic blood flow. Clearance of indo...

    Authors: Ulrich Mayr, Leonie Fahrenkrog-Petersen, Gonzalo Batres-Baires, Alexander Herner, Sebastian Rasch, Roland M. Schmid, Wolfgang Huber and Tobias Lahmer

    Citation: Annals of Intensive Care 2018 8:78

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  20. Content type: Research

    Acute kidney injury (AKI) is frequent and associated with poor outcome in intensive care unit (ICU) patients. Besides the association with short- and long-term mortality, the increased risk of chronic kidney ...

    Authors: Guillaume Geri, Bénédicte Stengel, Christian Jacquelinet, Philippe Aegerter, Ziad A. Massy and Antoine Vieillard-Baron

    Citation: Annals of Intensive Care 2018 8:77

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  21. Content type: Research

    The diagnostic value of hemoglobin (Hb) for detecting a significant hemorrhage (SH) in the early phase of trauma remains controversial. The present study aimed to assess the abilities of Hb measurements taken ...

    Authors: S. Figueiredo, C. Taconet, A. Harrois, S. Hamada, T. Gauss, M. Raux and J. Duranteau

    Citation: Annals of Intensive Care 2018 8:76

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  22. Content type: Research

    Upper gastrointestinal endoscopies’ (UGE) profitability is undisputable in patients admitted for an overt upper digestive tract bleeding. In critically ill subjects admitted for other causes, its performances ...

    Authors: Sylvain Jean-Baptiste, Jonathan Messika, David Hajage, Stéphane Gaudry, Julie Barbieri, Henri Duboc, Didier Dreyfuss, Benoit Coffin and Jean-Damien Ricard

    Citation: Annals of Intensive Care 2018 8:75

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  23. Content type: Research

    Cognitive dysfunction and delirium after ICU are frequent and may partially result from brain ischemia episodes. We hypothesized that systemic inflammation (severe sepsis or septic shock) modifies the control ...

    Authors: Matthieu Le Dorze, Florian Huché, Clément Coelembier, Christophe Rabuel and Didier Payen

    Citation: Annals of Intensive Care 2018 8:74

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  24. Content type: Review

    The bedside hemodynamic assessment of the critically ill remains challenging since blood volume, arterial–venous interaction and compliance are not measured directly. Mean circulatory filling pressure (Pmcf) is t...

    Authors: Marije Wijnberge, Daniko P. Sindhunata, Michael R. Pinsky, Alexander P. Vlaar, Else Ouweneel, Jos R. Jansen, Denise P. Veelo and Bart F. Geerts

    Citation: Annals of Intensive Care 2018 8:73

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  25. Content type: Research

    The rate, prognostic impacts, and predisposing factors of major vascular complications (MVCs) in patients underwent venoarterial extracorporeal membrane oxygenation (VA-ECMO) by surgical cut-down are poorly un...

    Authors: Feng Yang, Dengbang Hou, Jinhong Wang, Yongchao Cui, Xiaomeng Wang, Zhichen Xing, Chunjing Jiang, Xing Hao, Zhongtao Du, Xiaofang Yang, Yu Jiang and Xiaotong Hou

    Citation: Annals of Intensive Care 2018 8:72

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  26. Content type: Review

    Catheter-related blood-stream infections (CRBSIs) are the most common complication when using central venous catheters (CVCs). Whether coating CVCs under bundles could further reduce the incidence of CRBSIs is...

    Authors: Hongliang Wang, Hongshuang Tong, Haitao Liu, Yao Wang, Ruitao Wang, Hong Gao, Pulin Yu, Yanji Lv, Shuangshuang Chen, Guiyue Wang, Miao Liu, Yuhang Li, Kaijiang Yu and Changsong Wang

    Citation: Annals of Intensive Care 2018 8:71

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  27. Content type: Research

    Studies evaluating nicotine replacement therapy (NRT) to prevent nicotine withdrawal symptoms in ICU patients have yielded conflicting results. We performed a randomised controlled double-blind pilot study to ...

    Authors: Ben de Jong, Anne Sophie Schuppers, Arriette Kruisdijk-Gerritsen, Maurits Erwin Leo Arbouw, Hubertus Laurentius Antonius van den Oever and Arthur R. H. van Zanten

    Citation: Annals of Intensive Care 2018 8:70

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  28. Content type: Research

    Although enteral nutrition has become one of the standard therapies for patients with acute pancreatitis, the optimal formulae for enteral nutrition have been under debate. Elemental formula is assumed to be s...

    Authors: Akira Endo, Atsushi Shiraishi, Kiyohide Fushimi, Kiyoshi Murata and Yasuhiro Otomo

    Citation: Annals of Intensive Care 2018 8:69

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  29. Content type: Research

    In randomised controlled trials, procalcitonin (PCT)-guided antibiotic treatment has been proven to significantly reduce length of antibiotic therapy in intensive care unit (ICU) patients. However, concern was...

    Authors: Andreas Hohn, Nina Balfer, Bernhard Heising, Sabine Hertel, Jan C. Wiemer, Marcel Hochreiter and Stefan Schröder

    Citation: Annals of Intensive Care 2018 8:68

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  30. Content type: Research

    The hemodynamic effects of the passive leg raising (PLR) test must be assessed through a direct measurement of cardiac index (CI). We tested whether changes in Doppler common carotid blood flow (CBF) and commo...

    Authors: Valentina Girotto, Jean-Louis Teboul, Alexandra Beurton, Laura Galarza, Thierry Guedj, Christian Richard and Xavier Monnet

    Citation: Annals of Intensive Care 2018 8:67

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  31. Content type: Review

    In patients with septic shock, the administration of fluids during initial hemodynamic resuscitation remains a major therapeutic challenge. We are faced with many open questions regarding the type, dose and ti...

    Authors: Manu L. N. G. Malbrain, Niels Van Regenmortel, Bernd Saugel, Brecht De Tavernier, Pieter-Jan Van Gaal, Olivier Joannes-Boyau, Jean-Louis Teboul, Todd W. Rice, Monty Mythen and Xavier Monnet

    Citation: Annals of Intensive Care 2018 8:66

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  32. Content type: Research

    In order to decrease the incidence of ventilator-associated pneumonia (VAP) in Belgium, a national campaign for implementing a VAP bundle involving assessment of sedation, cuff pressure control, oral care with...

    Authors: Laurent Jadot, Luc Huyghens, Annick De Jaeger, Marc Bourgeois, Dominique Biarent, Adeline Higuet, Koen de Decker, Margot Vander Laenen, Baudewijn Oosterlynck, Patrick Ferdinande, Pascal Reper, Serge Brimioulle, Sophie Van Cromphaut, Stéphane Clement De Clety, Thierry Sottiaux and Pierre Damas

    Citation: Annals of Intensive Care 2018 8:65

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  33. Content type: Research

    Until now, the prognostic value of microcirculatory alterations in critically ill patients has been mainly evaluated in highly selected subgroups. Aim of this study is to monitor the microcirculation daily in ...

    Authors: Claudia Scorcella, Elisa Damiani, Roberta Domizi, Silvia Pierantozzi, Stefania Tondi, Andrea Carsetti, Silvia Ciucani, Valentina Monaldi, Mara Rogani, Benedetto Marini, Erica Adrario, Rocco Romano, Can Ince, E. Christiaan Boerma and Abele Donati

    Citation: Annals of Intensive Care 2018 8:64

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  34. Content type: Research

    In medical intensive care unit (MICU) patients, the predictors of post-discharge sleep disturbance and functional disability are poorly understood. ICU delirium is a risk factor with a plausible link to sleep ...

    Authors: Marcus T. Altman, Melissa P. Knauert, Terrence E. Murphy, Amy M. Ahasic, Zeeshan Chauhan and Margaret A. Pisani

    Citation: Annals of Intensive Care 2018 8:63

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  35. Content type: Research

    Metabolic acidosis is frequently observed as a consequence of global ischemia–reperfusion after out-of-hospital cardiac arrest (OHCA). We aimed to identify risk factors and assess the impact of metabolic acido...

    Authors: Matthieu Jamme, Omar Ben Hadj Salem, Lucie Guillemet, Pierre Dupland, Wulfran Bougouin, Julien Charpentier, Jean-Paul Mira, Frédéric Pène, Florence Dumas, Alain Cariou and Guillaume Geri

    Citation: Annals of Intensive Care 2018 8:62

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  36. Content type: Research

    A patient’s ability to clear secretions and protect the airway with an effective cough is an important part of the pre-extubation evaluation. An increase in intra-abdominal pressure (IAP) is important in gener...

    Authors: Yasuhiro Norisue, Jun Kataoka, Yosuke Homma, Takaki Naito, Junpei Tsukuda, Kentaro Okamoto, Takeshi Kawaguchi, Lonny Ashworth, Shimada Yumiko, Yuiko Hoshina, Eiji Hiraoka and Shigeki Fujitani

    Citation: Annals of Intensive Care 2018 8:61

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  37. Content type: Research

    Shock states are characterized by impaired tissue perfusion and microcirculatory alterations, which are directly related to outcome. Skin perfusion can be noninvasively evaluated using skin laser Doppler (SLD)...

    Authors: Diego Orbegozo, Wasineenart Mongkolpun, Gianni Stringari, Nikolaos Markou, Jacques Creteur, Jean-Louis Vincent and Daniel De Backer

    Citation: Annals of Intensive Care 2018 8:60

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  38. Content type: Research

    Septic patients often require sedation in intensive care unit, and midazolam is one of the most frequently used sedatives among them. But the interaction between midazolam and septic shock is not known. The ai...

    Authors: Jianxiao Chen, Tao Yu, Federico Longhini, Xiwen Zhang, Songqiao Liu, Ling Liu, Yi Yang and Haibo Qiu

    Citation: Annals of Intensive Care 2018 8:59

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  39. Content type: Research

    Ultrafast cooling by total liquid ventilation (TLV) provides potent cardio- and neuroprotection after experimental cardiac arrest. However, this was evaluated in animals with no initial lung injury, whereas ou...

    Authors: Jérôme Rambaud, Fanny Lidouren, Michaël Sage, Matthias Kohlhauer, Mathieu Nadeau, Étienne Fortin-Pellerin, Philippe Micheau, Luca Zilberstein, Nicolas Mongardon, Jean-Damien Ricard, Megumi Terada, Patrick Bruneval, Alain Berdeaux, Bijan Ghaleh, Hervé Walti and Renaud Tissier

    Citation: Annals of Intensive Care 2018 8:57

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  40. Content type: Research

    Anemia occurring as a result of inflammatory processes (anemia of inflammation, AI) has a high prevalence in critically ill patients. Knowledge on changes in iron metabolism during the course of AI is limited,...

    Authors: Margit Boshuizen, Jan M. Binnekade, Benjamin Nota, Kirsten van de Groep, Olaf L. Cremer, Pieter R. Tuinman, Janneke Horn, Marcus J. Schultz, Robin van Bruggen and Nicole P. Juffermans

    Citation: Annals of Intensive Care 2018 8:56

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  41. Content type: Research

    Diaphragm dysfunction is defined by a value of twitch tracheal pressure in response to magnetic phrenic stimulation (twitch pressure) amounting to less than 11 cmH2O. This study assessed whether this threshold or...

    Authors: Martin Dres, Ewan C. Goligher, Bruno-Pierre Dubé, Elise Morawiec, Laurence Dangers, Danielle Reuter, Julien Mayaux, Thomas Similowski and Alexandre Demoule

    Citation: Annals of Intensive Care 2018 8:53

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  42. Content type: Research

    Septic shock is a highly lethal condition. Early recognition of tissue hypoperfusion and its reversion are key factors for limiting progression to multiple organ dysfunction and death. Lactate-targeted resusci...

    Authors: Glenn Hernández, Alexandre Biasi Cavalcanti, Gustavo Ospina-Tascón, Fernando Godinho Zampieri, Arnaldo Dubin, F. Javier Hurtado, Gilberto Friedman, Ricardo Castro, Leyla Alegría, Maurizio Cecconi, Jean-Louis Teboul and Jan Bakker

    Citation: Annals of Intensive Care 2018 8:52

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