Bassetti M, Giacobbe DR, Vena A, Trucchi C, Ansaldi F, Antonelli M, et al. Incidence and outcome of invasive candidiasis in intensive care units (ICUs) in Europe: results of the EUCANDICU project. Crit Care. 2019;23(1):219.
Article
PubMed
PubMed Central
Google Scholar
Tsay SV, Mu Y, Williams S, Epson E, Nadle J, Bamberg WM, et al. Burden of candidemia in the united states, 2017. Clin Infect Dis. 2020. https://doi.org/10.1093/cid/ciaa193.
Article
PubMed
Google Scholar
Ghanem-Zoubi N, Zorbavel D, Khoury J, Geffen Y, Qasum M, Predescu S, et al. The association between treatment appropriateness according to EUCAST and CLSI breakpoints and mortality among patients with candidemia: a retrospective observational study. Eur J Clin Microbiol Infect Dis. 2018;37(12):2397–404.
Article
CAS
PubMed
Google Scholar
Luzzati R, Merelli M, Ansaldi F, Rosin C, Azzini A, Cavinato S, et al. Nosocomial candidemia in patients admitted to medicine wards compared to other wards: a multicentre study. Infection. 2016;44(6):747–55.
Article
PubMed
Google Scholar
Schwab F, Geffers C, Behnke M, Gastmeier P. ICU mortality following ICU-acquired primary bloodstream infections according to the type of pathogen: a prospective cohort study in 937 Germany ICUs (2006–2015). PLoS ONE. 2018;13(3):e0194210.
Article
PubMed
PubMed Central
CAS
Google Scholar
Novosad SA, Fike L, Dudeck MA, Allen-Bridson K, Edwards JR, Edens C, et al. Pathogens causing central-line-associated bloodstream infections in acute-care hospitals-United States, 2011–2017. Infect Control Hosp Epidemiol. 2020;41(3):313–9.
Article
PubMed
Google Scholar
Kett DH, Azoulay E, Echeverria PM, Vincent JL. Extended Prevalence of infection in ICUSGOI. Candida bloodstream infections in intensive care units: analysis of the extended prevalence of infection in intensive care unit study. Crit Care Med. 2011;39(4):665–70.
Article
PubMed
Google Scholar
Montagna MT, Caggiano G, Lovero G, De Giglio O, Coretti C, Cuna T, et al. Epidemiology of invasive fungal infections in the intensive care unit: results of a multicenter Italian survey (AURORA Project). Infection. 2013;41(3):645–53.
Article
CAS
PubMed
PubMed Central
Google Scholar
Pfaller M, Neofytos D, Diekema D, Azie N, Meier-Kriesche HU, Quan SP, et al. Epidemiology and outcomes of candidemia in 3648 patients: data from the Prospective Antifungal Therapy (PATH Alliance(R)) registry, 2004–2008. Diagn Microbiol Infect Dis. 2012;74(4):323–31.
Article
PubMed
Google Scholar
Garnacho-Montero J, Diaz-Martin A, Garcia-Cabrera E, de Pipaon RPM, Hernandez-Caballero C, Aznar-Martin J, et al. Risk factors for fluconazole-resistant candidemia. Antimicrob Agents Chemotherapy. 2010;54(8):3149–54.
Article
CAS
Google Scholar
Lortholary O, Desnos-Ollivier M, Sitbon K, Fontanet A, Bretagne S, Dromer F, et al. Recent exposure to caspofungin or fluconazole influences the epidemiology of candidemia: a prospective multicenter study involving 2441 patients. Antimicrob Agents Chemotherapy. 2011;55(2):532–8.
Article
CAS
Google Scholar
Pappas PG, Kauffman CA, Andes DR, Clancy CJ, Marr KA, Ostrosky-Zeichner L, Guideline for the Management of Candidiasis, CP, et al. Update by the Infectious Diseases Society of America. Vol. 62, Clinical infectious diseases: an official publication of the Infectious Diseases Society of. America. 2016;2016:e1–50.
Google Scholar
Bassetti M, Merelli M, Ansaldi F, de Florentiis D, Sartor A, Scarparo C, et al. Clinical and therapeutic aspects of candidemia: a five year single centre study. Consolaro MEL, editor. PLoS ONE. 2015;10(5):e0127534.
Garey KW, Rege M, Pai MP, Mingo DE, Suda KJ, Turpin RS, et al. Time to initiation of fluconazole therapy impacts mortality in patients with candidemia: a multi-institutional study. Clin Infect Dis. 2006;43(1):25–31.
Article
CAS
PubMed
Google Scholar
León C, Ruiz-Santana S, Saavedra P, Almirante B, Nolla-Salas J, Alvarez-Lerma F, et al. A bedside scoring system (“Candida score”) for early antifungal treatment in nonneutropenic critically ill patients with Candida colonization. Crit Care Med. 2006;34(3):730–7.
Article
PubMed
Google Scholar
Bassetti M, Garnacho-Montero J, Calandra T, Kullberg B, Dimopoulos G, Azoulay E, et al. Intensive care medicine research agenda on invasive fungal infection in critically ill patients. Intensive Care Med. 2017;43(9):1225–38.
Article
CAS
PubMed
Google Scholar
León C, Ruiz-Santana S, Saavedra P, Galván B, Blanco A, Castro C, et al. Usefulness of the “Candida score” for discriminating between Candida colonization and invasive candidiasis in non-neutropenic critically ill patients: a prospective multicenter study. Crit Care Med. 2009;37(5):1624–33.
Article
PubMed
Google Scholar
Bassetti M, Righi E, Ansaldi F, Merelli M, Trucchi C, Cecilia T, et al. A multicenter study of septic shock due to candidemia: outcomes and predictors of mortality. Intensive Care Med. 2014;40(6):839–45.
Article
CAS
PubMed
Google Scholar
Sbrana F, Sozio E, Bassetti M, Ripoli A, Pieralli F, Azzini AM, et al. Independent risk factors for mortality in critically ill patients with candidemia on Italian Internal Medicine Wards. Intern Emerg Med. 2018;13(2):199–204.
Article
PubMed
Google Scholar
Baldesi O, Bailly S, Ruckly S, Lepape A, L'Heriteau F, Aupee M, et al. ICU-acquired candidaemia in France: epidemiology and temporal trends, 2004–2013—a study from the REA-RAISIN network. J Infect. 2017;75(1):59–67.
Article
PubMed
Google Scholar
Ghrenassia E, Mokart D, Mayaux J, Demoule A, Rezine I, Kerhuel L, et al. Candidemia in critically ill immunocompromised patients: report of a retrospective multicenter cohort study. Ann Intensive Care. 2019;9(1):62–10.
Article
PubMed
PubMed Central
Google Scholar
Bennett JE, Powers JH. Candidemia in the ICU: does initial antifungal matter? Crit Care Med. 2018;46(3):482–3.
Article
PubMed
PubMed Central
Google Scholar
Falcone M, Tiseo G, Gutiérrez-Gutiérrez B, Raponi G, Carfagna P, Rosin C, et al. Impact of initial antifungal therapy on the outcome of patients with Candidemia and septic shock admitted to medical wards: a propensity score-adjusted analysis. Open Forum Infect Dis. 2019;6(7):ofz251.
Article
PubMed
PubMed Central
CAS
Google Scholar
Garnacho-Montero J, Diaz-Martin A, Cantón-Bulnes L, Ramírez P, Sierra R, Arias-Verdú D, et al. Initial antifungal strategy reduces mortality in critically Ill patients with candidemia: a propensity score-adjusted analysis of a multicenter study. Crit Care Med. 2018;46(3):384–93.
Article
PubMed
Google Scholar
Reboli AC, Rotstein C, Pappas PG, Chapman SW, Kett DH, Kumar D, et al. Anidulafungin versus fluconazole for invasive candidiasis. N Engl J Med. 2007;356(24):2472–82.
Article
CAS
PubMed
Google Scholar
Vena A, Bouza E, Valerio M, Padilla B, Paño-Pardo JR, Fernández-Ruiz M, et al. Candidemia in non-ICU surgical wards: Comparison with medical wards. Sturtevant J, editor. PLoS ONE. 2017;12(10):e0185339.
De Rosa FG, Trecarichi EM, Montrucchio C, Losito AR, Raviolo S, Posteraro B, et al. Mortality in patients with early- or late-onset candidaemia. J Antimicrob Chemother. 2013;68(4):927–35.
Article
PubMed
CAS
Google Scholar
Lambden S, Laterre PF, Levy MM, Francois B. The SOFA score-development, utility and challenges of accurate assessment in clinical trials. Crit Care. 2019;23(1):374–9.
Article
PubMed
PubMed Central
Google Scholar
Haltmeier T, Inaba K, Effron Z, Dollbaum R, Shulman IA, Benjamin E, et al. Candida score as a predictor of worse outcomes and mortality in severely injured trauma patients with positive candida cultures. Am Surg. 2015;81(10):1067–73.
Article
PubMed
Google Scholar
Le Gall JR, Lemeshow S, Saulnier F. A new simplified acute physiology score (SAPS II) based on a European/North American multicenter study. JAMA. 1993;270(24):2957–63.
Article
PubMed
Google Scholar
McPhail MJW, Parrott F, Wendon JA, Harrison DA, Rowan KA, Bernal W. Incidence and outcomes for patients with cirrhosis admitted to the united kingdom critical care units. Crit Care Med. 2018;46(5):705–12.
Article
PubMed
PubMed Central
Google Scholar
Barchiesi F, Orsetti E, Gesuita R, Skrami E, Manso E, Candidemia Study G. Epidemiology, clinical characteristics, and outcome of candidemia in a tertiary referral center in Italy from 2010 to 2014. Infection. 2016;44(2):205–13.
Article
PubMed
Google Scholar
Tortorano AM, Dho G, Prigitano A, Breda G, Grancini A, Emmi V, et al. Invasive fungal infections in the intensive care unit: a multicentre, prospective, observational study in Italy (2006–2008). Mycoses. 2012;55(1):73–9.
Article
PubMed
Google Scholar
Goemaere B, Becker P, Van Wijngaerden E, Maertens J, Spriet I, Hendrickx M, et al. Increasing candidaemia incidence from 2004 to 2015 with a shift in epidemiology in patients preexposed to antifungals. Mycoses. 2018;61(2):127–33.
Article
CAS
PubMed
Google Scholar
Sasso M, Roger C, Sasso M, Poujol H, Barbar S, Lefrant JY, et al. Changes in the distribution of colonising and infecting Candida spp. isolates, antifungal drug consumption and susceptibility in a French intensive care unit: a 10-year study. Mycoses. 2017;60(12):770–80.
Article
CAS
PubMed
Google Scholar
Satoh K, Makimura K, Hasumi Y, Nishiyama Y, Uchida K, Yamaguchi H. Candida auris sp. Nov., a novel ascomycetous yeast isolated from the external ear canal of an inpatient in a Japanese hospital. Microbiol Immunol. 2009;53(1):41–4.
Article
CAS
PubMed
Google Scholar
Chowdhary A, Sharma C, Meis JF. Candida auris: a rapidly emerging cause of hospital-acquired multidrug-resistant fungal infections globally. PLoS Pathog. 2017;13(5):e1006290.
Article
PubMed
PubMed Central
CAS
Google Scholar
Cortegiani A, Misseri G, Giarratano A, Bassetti M, Eyre D. The global challenge of Candida auris in the intensive care unit. Crit Care. 2019;23(1):150.
Article
PubMed
PubMed Central
Google Scholar
Eyre DW, Sheppard AE, Madder H, Moir I, Moroney R, Quan TP, et al. A Candida auris outbreak and its control in an intensive care setting. N Engl J Med. 2018;379(14):1322–31.
Article
PubMed
Google Scholar
Schelenz S, Hagen F, Rhodes JL, Abdolrasouli A, Chowdhary A, Hall A, et al. First hospital outbreak of the globally emerging Candida auris in a European hospital. Antimicrob Resistance Infect Control. 2016;5:35.
Article
Google Scholar
Martin-Loeches I, Antonelli M, Cuenca-Estrella M, Dimopoulos G, Einav S, De Waele JJ, et al. ESICM/ESCMID task force on practical management of invasive candidiasis in critically ill patients. Intensive Care Med. 2019;45(6):789–805.
Article
PubMed
Google Scholar
Rouze A, Loridant S, Poissy J, Dervaux B, Sendid B, Cornu M, et al. Biomarker-based strategy for early discontinuation of empirical antifungal treatment in critically ill patients: a randomized controlled trial. Intensive Care Med. 2017;43(11):1668–777.
Article
CAS
PubMed
Google Scholar
Alves PGV, Melo SGO, de Bessa MAS, de Brito MO, de Menezes RP, de Araújo LB, et al. Risk factors associated with mortality among patients who had candidemia in a university hospital. Rev Soc Bras Med Trop. 2020;53(7):e20190206.
Article
PubMed
PubMed Central
Google Scholar
Marchena-Gomez J, Saez-Guzman T, Hemmersbach-Miller M, Conde-Martel A, Morales-Leon V, Bordes-Benitez A, et al. Candida isolation in patients hospitalized on a surgical ward: significance and mortality-related factors. World J Surg. 2009;33(9):1822–9.
Article
CAS
PubMed
Google Scholar
Weinberger M, Leibovici L, Perez S, Samra Z, Ostfeld I, Levi I, et al. Characteristics of candidaemia with Candida-albicans compared with non-albicans Candida species and predictors of mortality. J Hosp Infect. 2005;61(2):146–54.
Article
CAS
PubMed
Google Scholar
Chakrabarti A, Sood P, Rudramurthy SM, Chen S, Kaur H, Capoor M, et al. Incidence, characteristics and outcome of ICU-acquired candidemia in India. Intensive Care Med. 2015;41(2):285–95.
Article
PubMed
Google Scholar
Groeneveld JA. Mortality as an endpoint in studies in critically ill patients: a reappraisal of definitions. Minerva Anestesiol. 2016;82(7):785–90.
PubMed
Google Scholar