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  1. Before discharging a patient from the ICU, an adequate patient evaluation is needed to detect individuals as high risk for unfavorable outcome. A pro- or anti-inflammatory status is a potential risk factor fo...

    Authors: S. Sophie Gülcher, Nynke A. Bruins, W. Peter Kingma and E. Christiaan Boerma
    Citation: Annals of Intensive Care 2016 6:5
  2. Therapeutic hypothermia (TH between 32 and 34 °C) was recommended until recently in unconscious successfully resuscitated cardiac arrest (CA) patients, especially after initial shockable rhythm. A randomized c...

    Authors: Nicolas Deye, François Vincent, Philippe Michel, Stephan Ehrmann, Daniel da Silva, Michael Piagnerelli, Antoine Kimmoun, Olfa Hamzaoui, Jean-Claude Lacherade, Bernard de Jonghe, Florence Brouard, Corinne Audoin, Xavier Monnet and Pierre-François Laterre
    Citation: Annals of Intensive Care 2016 6:4
  3. Due to the limited data available in the pediatric population and lack of interventional studies to show that administration of vitamin D indeed improves clinical outcomes, opinion is still divided as to wheth...

    Authors: Jhuma Sankar, Wonashi Lotha, Javed Ismail, C. Anubhuti, Rameshwar S. Meena and M. Jeeva Sankar
    Citation: Annals of Intensive Care 2016 6:3
  4. In the context of recent guidelines on invasive candidiasis (IC), how French intensive care units (ICUs) are managing IC?

    Authors: Olivier Leroy, Sébastien Bailly, Jean-Pierre Gangneux, Jean-Paul Mira, Patrick Devos, Hervé Dupont, Philippe Montravers, Pierre-François Perrigault, Jean-Michel Constantin, Didier Guillemot, Elie Azoulay, Olivier Lortholary, Caroline Bensoussan and Jean-François Timsit
    Citation: Annals of Intensive Care 2016 6:2
  5. Hyponatremia is the most common electrolyte disturbance in hospitalized patients, and it represents a well-established risk factor for ICU/hospital mortality. The majority of hyponatremic states are associated...

    Authors: Michele Umbrello, Elena S. Mantovani, Paolo Formenti, Claudia Casiraghi, Davide Ottolina, Martina Taverna, Angelo Pezzi, Giovanni Mistraletti and Gaetano Iapichino
    Citation: Annals of Intensive Care 2016 6:1
  6. Acute renal failure (ARF) in critically ill patients is currently very frequent and requires renal replacement therapy (RRT) in many patients. During the last 15 years, several studies have considered importan...

    Authors: Christophe Vinsonneau, Emma Allain-Launay, Clarisse Blayau, Michael Darmon, Damien du Cheyron, Theophile Gaillot, Patrick M. Honore, Etienne Javouhey, Thierry Krummel, Annie Lahoche, Serge Letacon, Matthieu Legrand, Mehran Monchi, Christophe Ridel, René Robert, Frederique Schortgen…
    Citation: Annals of Intensive Care 2015 5:58
  7. Early after intubation, a layer of biofilm covers the inner lumen of the endotracheal tube (ETT). Cleaning the ETT might prevent airways colonization by pathogens, reduce resistance to airflow, and decrease su...

    Authors: Andrea Coppadoro, Giacomo Bellani, Alfio Bronco, Alberto Lucchini, Simone Bramati, Vanessa Zambelli, Roberto Marcolin and Antonio Pesenti
    Citation: Annals of Intensive Care 2015 5:57
  8. Echocardiography and the N-terminal pro-brain-type natriuretic peptide (NT-proBNP) level are important tests for assessing left ventricular function in patients presenting to the emergency department with acute d...

    Authors: Zouheir Bitar, Ossama Maadarani and Khaled Almerri
    Citation: Annals of Intensive Care 2015 5:56
  9. The potential influence of bed availability on triage to intensive care unit (ICU) admission is among the factors that may influence the ideal ratio of ICU beds to population: thus, high bed availability (HBA)...

    Authors: René Robert, Rémi Coudroy, Stéphanie Ragot, Olivier Lesieur, Isabelle Runge, Vincent Souday, Arnaud Desachy, Jean-Paul Gouello, Michel Hira, Mouldi Hamrouni and Jean Reignier
    Citation: Annals of Intensive Care 2015 5:55
  10. While a systematic approach to weaning reduces the rate of extubation failure in intubated brain-injured patients, no data are available on the weaning outcome of these patients after tracheotomy. We aimed to ...

    Authors: Rosanna Vaschetto, Pamela Frigerio, Maurizio Sommariva, Arianna Boggero, Valentina Rondi, Francesca Grossi, Silvio Cavuto, Stefano Nava, Francesco Della Corte and Paolo Navalesi
    Citation: Annals of Intensive Care 2015 5:54
  11. Since the overall prognosis of very elderly patients is generally limited, admissions to intensive care in these patients are often restricted. Therefore, only very few information is available on the prognosi...

    Authors: Sophie Becker, Jakob Müller, Geraldine de Heer, Stephan Braune, Valentin Fuhrmann and Stefan Kluge
    Citation: Annals of Intensive Care 2015 5:53
  12. A reliable predictor for early recovery of consciousness in comatose patients is of great clinical significance. Here we aimed to investigate the potentially prognostic value of electroencephalogram-reactivity...

    Authors: Xiao-gang Kang, Feng Yang, Wen Li, Chen Ma, Li Li and Wen Jiang
    Citation: Annals of Intensive Care 2015 5:52
  13. Sepsis-induced acute kidney injury (SAKI) remains an important challenge in critical care medicine. We reviewed current available evidence on prevention and treatment of SAKI with focus on some recent advances...

    Authors: Patrick M. Honore, Rita Jacobs, Inne Hendrickx, Sean M. Bagshaw, Olivier Joannes-Boyau, Willem Boer, Elisabeth De Waele, Viola Van Gorp and Herbert D. Spapen
    Citation: Annals of Intensive Care 2015 5:51
  14. Acute kidney injury (AKI) is a common complication after cardiac surgery. Currently, prediction of AKI with classical tools remains uncertain. Therefore, it was the aim of the present study to evaluate two ne...

    Authors: Kevin Pilarczyk, Michaela Edayadiyil-Dudasova, Daniel Wendt, Ender Demircioglu, Jaroslav Benedik, Daniel Sebastian Dohle, Heinz Jakob and Fabian Dusse
    Citation: Annals of Intensive Care 2015 5:50
  15. In ICU patients with normal serum creatinine (SCr), a state of increased renal drug excretion has been described (creatinine clearance ≥130 ml/min/1.73 m2), and named augmented renal clearance (ARC). In ICU patie...

    Authors: Stéphanie Ruiz, Vincent Minville, Karim Asehnoune, Marie Virtos, Bernard Georges, Olivier Fourcade and Jean-Marie Conil
    Citation: Annals of Intensive Care 2015 5:49
  16. Sepsis is a common condition that has a high mortality and morbidity that need prompt diagnosis and treatment. Biomarkers like Soluble CD14 subtype (sCD14-ST, presepsin) may be useful in identifying patients w...

    Authors: Zhongjun Zheng, Libing Jiang, Ligang Ye, Yuzhi Gao, Luping Tang and Mao Zhang
    Citation: Annals of Intensive Care 2015 5:48
  17. Hepatic impairment is found in up to 20 % in critically ill patients. Hypoxic/ischemic hepatitis (HH) is a diffuse hepatic damage associated with high morbidity and mortality. Indocyanine green plasma disappe...

    Authors: Thomas Horvatits, Nikolaus Kneidinger, Andreas Drolz, Kevin Roedl, Karoline Rutter, Stefan Kluge, Michael Trauner and Valentin Fuhrmann
    Citation: Annals of Intensive Care 2015 5:47
  18. Thrombocytopenia is a frequent finding in critically ill cancer patients for whom indications of platelet transfusions are unclear. We herein addressed the current practices in platelet transfusion and the ris...

    Authors: Bassem Habr, Julien Charpentier, Benoît Champigneulle, Agnès Dechartres, Fabrice Daviaud, Guillaume Geri, Alain Cariou, Jean-Daniel Chiche, Jean-Paul Mira and Frédéric Pène
    Citation: Annals of Intensive Care 2015 5:46
  19. Very few studies focused on patients with severe infective endocarditis (IE) and multiple complications leading to Intensive Care Unit (ICU) admission. Studied primary outcomes depended on the series and multi...

    Authors: Olivier Leroy, Hugues Georges, Patrick Devos, Steve Bitton, Nathalie De Sa, Céline Dedrie, Sébastien Beague, Pierre Ducq, Claire Boulle-Geronimi, Damien Thellier, Fabienne Saulnier and Sebastien Preau
    Citation: Annals of Intensive Care 2015 5:45
  20. Patients in the intensive care unit (ICU) are more prone to drug–drug interactions (DDIs). The software and charts that indicate all interactions may not be proper for clinical usage. This study aimed to ident...

    Authors: Shadi Baniasadi, Behrooz Farzanegan and Maryam Alehashem
    Citation: Annals of Intensive Care 2015 5:44
  21. Underinflation of tracheal cuff is a risk factor for microaspiration of contaminated secretions and subsequent ventilator-associated pneumonia (VAP). The aim of this collaborative meta-analysis of individual p...

    Authors: Saad Nseir, Leonardo Lorente, Miquel Ferrer, Anahita Rouzé, Oswaldo Gonzalez, Gianluigi Li Bassi, Alain Duhamel and Antoni Torres
    Citation: Annals of Intensive Care 2015 5:43
  22. This review summarizes the (patho)-physiological effects of ventilation with high FiO2 (0.8–1.0), with a special focus on the most recent clinical evidence on its use for the management of circulatory shock and d...

    Authors: Sebastian Hafner, François Beloncle, Andreas Koch, Peter Radermacher and Pierre Asfar
    Citation: Annals of Intensive Care 2015 5:42
  23. This review examines the available evidence for targeting a specific mean arterial pressure (MAP) in sepsis resuscitation. The clinical data suggest that targeting an MAP of 65–70 mmHg in patients with septic ...

    Authors: Ryotaro Kato and Michael R. Pinsky
    Citation: Annals of Intensive Care 2015 5:41
  24. Norepinephrine is a key drug for treating shock but has a short half-life that requires continuous intravenous administration to maintain the constant plasma concentration needed to obtain a stable blood press...

    Authors: Emilie Greau, Jean-Baptiste Lascarrou, Aurélie Le Thuaut, Nathalie Maquigneau, Yolaine Alcourt, Anne Coutolleau, Cécile Rousseau, Vanessa Erragne and Jean Reignier
    Citation: Annals of Intensive Care 2015 5:40
  25. Hyponatremia is a common electrolyte derangement in the setting of the intensive care unit. Life-threatening neurological complications may arise not only in case of a severe (<120 mmol/L) and acute fall of p...

    Authors: Cédric Rafat, Martin Flamant, Stéphane Gaudry, Emmanuelle Vidal-Petiot, Jean-Damien Ricard and Didier Dreyfuss
    Citation: Annals of Intensive Care 2015 5:39
  26. There is much controversy around the optimal caloric intake in intensive care unit (ICU) patients, based on the diverging results of prospective studies. Therefore, we assessed the presence of an association b...

    Authors: Isabel Carolina Reis Crosara, Christian Mélot and Jean-Charles Preiser
    Citation: Annals of Intensive Care 2015 5:37
  27. In critically ill children, in-line microfilters may reduce the incidence of the systemic inflammatory response syndrome (SIRS), the overall complication and organ dysfunction rate. No data on the use of in-li...

    Authors: Ilse Gradwohl-Matis, Andreas Brunauer, Daniel Dankl, Elisabeth Wirthel, Ingeborg Meburger, Angela Bayer, Michaela Mandl, Martin W. Dünser and Wilhelm Grander
    Citation: Annals of Intensive Care 2015 5:36
  28. Data are sparse regarding the effects of prolonged prone positioning (PP) during VV-ECMO. Previous studies, using short sessions (<12 h), failed to find any effects on respiratory system compliance. In the pre...

    Authors: Antoine Kimmoun, Sylvain Roche, Céline Bridey, Fabrice Vanhuyse, Renaud Fay, Nicolas Girerd, Damien Mandry and Bruno Levy
    Citation: Annals of Intensive Care 2015 5:35
  29. We retrospectively studied associations between bolus infusion of hydrocortisone and variability of the blood glucose level and changes in insulin rates in intensive care unit (ICU) patients.

    Authors: Roosmarijn T. M. van Hooijdonk, Jan M. Binnekade, Lieuwe D. J. Bos, Janneke Horn, Nicole P. Juffermans, Ameen Abu-Hanna and Marcus J. Schultz
    Citation: Annals of Intensive Care 2015 5:34
  30. Dexmedetomidine (DEX) is a centrally acting alpha-2-adrenoceptor agonist that has potential in the management of alcohol withdrawal syndrome (AWS) owing to its ability to produce arousable sedation and to inhi...

    Authors: Kateryna Bielka, Iurii Kuchyn and Felix Glumcher
    Citation: Annals of Intensive Care 2015 5:33
  31. Empiric antibiotic therapy is routinely prescribed in patients with acute COPD exacerbations (AECOPD) requiring ventilatory support on the basis of studies including patients conventionally ventilated. Whether...

    Authors: Islem Ouanes, Lamia Ouanes-Besbes, Saoussen Ben Abdallah, Fahmi Dachraoui and Fekri Abroug
    Citation: Annals of Intensive Care 2015 5:30
  32. Sepsis and septic shock is characterized by oxidative stress that mainly promotes systemic inflammation and organ failure due to excessive free radical production and depletion of antioxidant defenses. Theref...

    Authors: Legese Chelkeba, Arezoo Ahmadi, Mohammad Abdollahi, Atabak Najafi, Mohammad Hosein Ghadimi, Reza Mosaed and Mojtaba Mojtahedzadeh
    Citation: Annals of Intensive Care 2015 5:29
  33. In patients with hematological malignancies and acute respiratory failure (ARF), noninvasive ventilation was associated with a decreased mortality in older studies. However, mortality of intubated patients dec...

    Authors: Virginie Lemiale, Matthieu Resche-Rigon, Djamel Mokart, Frederic Pène, Antoine Rabbat, Achille Kouatchet, François Vincent, Fabrice Bruneel, Martine Nyunga, Christine Lebert, Pierre Perez, Anne-Pascale Meert, Dominique Benoit, Sylvie Chevret and Elie Azoulay
    Citation: Annals of Intensive Care 2015 5:28
  34. The aims of this study were to prospectively assess the prevalence of sustained (lasting more than 30 s) new-onset supraventricular arrhythmia (NOSVA) during septic shock, identify the associated factors (incl...

    Authors: Aurélien Seemann, Florence Boissier, Keyvan Razazi, Guillaume Carteaux, Nicolas de Prost, Christian Brun-Buisson and Armand Mekontso Dessap
    Citation: Annals of Intensive Care 2015 5:27
  35. Authors: Bruno Levy, Olivier Bastien, Karim Bendjelid, Alain Cariou, Tahar Chouihed, Alain Combes, Alexandre Mebazaa, Bruno Megarbane, Patrick Plaisance, Alexandre Ouattara, Christian Spaulding, Jean-Louis Teboul, Fabrice Vanhuyse, Thierry Boulain and Kaldoun Kuteifan
    Citation: Annals of Intensive Care 2015 5:26

    The original article was published in Annals of Intensive Care 2015 5:17

  36. High-frequency oscillatory ventilation (HFOV) does not improve the prognosis of ARDS patients despite an improvement in oxygenation. This paradox may partly be explained by HFOV hemodynamic side-effects on rig...

    Authors: Lionel Ursulet, Arnaud Roussiaux, Dominique Belcour, Cyril Ferdynus, Bernard-Alex Gauzere, David Vandroux and Julien Jabot
    Citation: Annals of Intensive Care 2015 5:25
  37. Discharge destination after critical illness is increasingly recognized as a valuable patient-centered outcome. Recently, vitamin D status has been shown to be associated with important outcomes such as length...

    Authors: Karolina Brook, Carlos A. Camargo, Kenneth B. Christopher and Sadeq A. Quraishi
    Citation: Annals of Intensive Care 2015 5:23
  38. Jean-Luc Diehl The French Intensive Care Society organized on 5th and 6th June 2014 its 4th “Paris International Conference in Intensive Care”, whose principle is to bring together the be...

    Authors: Peter J. Kudenchuk, Claudio Sandroni, Hendrik R. Drinhaus, Bernd W. Böttiger, Alain Cariou, Kjetil Sunde, Martin Dworschak, Fabio Silvio Taccone, Nicolas Deye, Hans Friberg, Steven Laureys, Didier Ledoux, Mauro Oddo, Stéphane Legriel, Philippe Hantson, Jean-Luc Diehl…
    Citation: Annals of Intensive Care 2015 5:22
  39. The burden of multidrug resistance in Gram-negative bacilli (GNB) now represents a daily issue for the management of antimicrobial therapy in intensive care unit (ICU) patients. In Enterobacteriaceae, the dramati...

    Authors: Étienne Ruppé, Paul-Louis Woerther and François Barbier
    Citation: Annals of Intensive Care 2015 5:21
  40. To improve the delivery of important care processes in the ICU, morning ward round checklists have been implemented in a number of intensive care units (ICUs) internationally. Good quality evidence supporting ...

    Authors: Karena M Conroy, Doug Elliott and Anthony R Burrell
    Citation: Annals of Intensive Care 2015 5:20
  41. We aim to demonstrate behavioral alterations in a sepsis model using intravenous (IV) immunoglobulin G (IgG) and immunoglobulins enriched with IgA and IgM (IgGAM).

    Authors: Perihan Ergin Ozcan, Evren Senturk, Gunseli Orhun, Salih Gumru, Nadir Arican, Nurcan Orhan, Canan Ugur Yılmaz, Mehmet Kaya, Feyza Aricioglu and Figen Esen
    Citation: Annals of Intensive Care 2015 5:19
  42. There have been few studies that have evaluated the quality of end-of-life care (EOLC) for cancer patients in the ICU. The aim of this study was to explore the quality of transition to EOLC for cancer patient...

    Authors: Sophie J Miller, Nishita Desai, Natalie Pattison, Joanne M Droney, Angela King, Paul Farquhar-Smith and Pascale C Gruber
    Citation: Annals of Intensive Care 2015 5:18
  43. Unlike for septic shock, there are no specific international recommendations regarding the management of cardiogenic shock (CS) in critically ill patients. We present herein recommendations for the management ...

    Authors: Bruno Levy, Olivier Bastien, Karim Bendjelid, Alain Cariou, Tahar Chouihed, Alain Combes, Alexandre Mebazaa, Bruno Megarbane, Patrick Plaisance, Alexandre Ouattara, Christian Spaulding, Jean-Louis Teboul, Fabrice Vanhuyse, Thierry Boulain and Kaldoun Kuteifan
    Citation: Annals of Intensive Care 2015 5:17

    The Erratum to this article has been published in Annals of Intensive Care 2015 5:26

  44. Most studies about septic shock report a crude mortality rate that neither distinguishes between early and late deaths nor addresses the direct causes of death. We herein aimed to determine the modalities of d...

    Authors: Fabrice Daviaud, David Grimaldi, Agnès Dechartres, Julien Charpentier, Guillaume Geri, Nathalie Marin, Jean-Daniel Chiche, Alain Cariou, Jean-Paul Mira and Frédéric Pène
    Citation: Annals of Intensive Care 2015 5:16
  45. In France, decisions to limit treatment fall under the Leonetti law adopted in 2005. Leading figures from the French world of politics, science, and justice recently claimed for amendments to the law, consider...

    Authors: Olivier Lesieur, Maxime Leloup, Frédéric Gonzalez and Marie-France Mamzer
    Citation: Annals of Intensive Care 2015 5:15
  46. Patients with severe cardiogenic pulmonary edema (CPE) are frequently hypercapnic, possibly because of associated underlying chronic lung disease (CLD). Since hypercapnia has been associated with outcome, we a...

    Authors: Damien Contou, Chiara Fragnoli, Ana Córdoba-Izquierdo, Florence Boissier, Christian Brun-Buisson and Arnaud W Thille
    Citation: Annals of Intensive Care 2015 5:14

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