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  1. Cuff pressure (P cuff) control is mandatory to avoid leakage of oral secretions passing the tracheal tube and tracheal ischemia. The aim of the present trial was to determine the efficacy of a m...

    Authors: Saad Nseir, Andrey Rodriguez, Paula Saludes, Julien De Jonckheere, Jordi Valles, Antonio Artigas and Ignacio Martin-Loeches
    Citation: Annals of Intensive Care 2015 5:12
  2. Vancomycin during continuous venovenous hemofiltration (CVVH) is either administered by intermittent infusion (II) or continuous infusion (CI). In this patient population, the best method to rapidly achieve ta...

    Authors: Hsin Lin, Yana Bukovskaya, Marc De Moya, Jarone Lee and Ulrich Schmidt
    Citation: Annals of Intensive Care 2015 5:10
  3. The purpose of this study is to compare the in-hospital mortality rates between septic patients receiving statins and those that did not prior to developing sepsis. We compared subgroups receiving atorvastatin...

    Authors: Daniel R Ouellette, Erics Espinoza Moscoso, Julio Pinto Corrales and Michael Peters
    Citation: Annals of Intensive Care 2015 5:9
  4. Experimental research has always been the cornerstone of pathophysiological and therapeutic advances in critical care medicine, where clinical observations and basic research mutually fed each other in a so-ca...

    Authors: Frédéric Pène, Hafid Ait-Oufella, Fabio Silvio Taccone, Guillaume Monneret, Tarek Sharshar, Fabienne Tamion and Jean-Paul Mira
    Citation: Annals of Intensive Care 2015 5:8
  5. The triage nurse is involved in the early identification of the most severe patients at emergency department (ED) presentation. However, clinical criteria alone may be insufficient to identify them correctly. ...

    Authors: Cyril Manzon, Loïc Barrot, Guillaume Besch, Olivier Barbot, Thibaut Desmettre, Gilles Capellier and Gaël Piton
    Citation: Annals of Intensive Care 2015 5:7
  6. Web-based decision aids are increasingly important in medical research and clinical care. However, few have been studied in an intensive care unit setting. The objectives of this study were to develop a Web-ba...

    Authors: Christopher E Cox, Nicholas G Wysham, Brenda Walton, Derek Jones, Brian Cass, Maria Tobin, Mattias Jonsson, Jeremy M Kahn, Douglas B White, Catherine L Hough, Carmen L Lewis and Shannon S Carson
    Citation: Annals of Intensive Care 2015 5:6
  7. Transpulmonary bubble transit (TPBT) detected with contrast echocardiography is reported as a sign of intrapulmonary shunt during cirrhosis or exercise in healthy humans. However, its physiological meaning is ...

    Authors: Florence Boissier, Keyvan Razazi, Arnaud W Thille, Ferran Roche-Campo, Rusel Leon, Emmanuel Vivier, Laurent Brochard, Christian Brun-Buisson and Armand Mekontso Dessap
    Citation: Annals of Intensive Care 2015 5:5
  8. Noninvasive positive-pressure ventilation (NIPPV) use has increased in the treatment of patients with respiratory failure. However, despite decreasing the need for intubation in some patients, there are no dat...

    Authors: Jarrod M Mosier, John C Sakles, Sage P Whitmore, Cameron D Hypes, Danielle K Hallett, Katharine E Hawbaker, Linda S Snyder and John W Bloom
    Citation: Annals of Intensive Care 2015 5:4
  9. In acute respiratory failure, arterial blood gas analysis (ABG) is used to diagnose hypercapnia. Once non-invasive ventilation (NIV) is initiated, ABG should at least be repeated within 1 h to assess PaCO2 respon...

    Authors: Lise Piquilloud, David Thevoz, Philippe Jolliet and Jean-Pierre Revelly
    Citation: Annals of Intensive Care 2015 5:2
  10. The purpose of the study was to assess blood flow in the upper limb arteries after prolonged catheterization with long radial artery catheters (LRC) which reach the subclavian artery compared to catheterizatio...

    Authors: Lucas Rovira, Gerardo Aguilar, Alberto Cuñat and Francisco J Belda
    Citation: Annals of Intensive Care 2015 5:1
  11. Availability of a patient data management system (PDMS) has created the opportunity to develop trigger-based electronic surveillance systems (ESSs). The aim was to evaluate a semi-automated trigger-based ESS f...

    Authors: Anna Maria Kaiser, Evelien de Jong, Sabine FM Evelein-Brugman, Jan M Peppink, Christina MJE Vandenbroucke-Grauls and Armand RJ Girbes
    Citation: Annals of Intensive Care 2014 4:40
  12. This study was performed to compare intestinal and sublingual microcirculation and their response to a fluid challenge.

    Authors: Vanina Siham Kanoore Edul, Can Ince, Noelia Navarro, Luciana Previgliano, Alejandro Risso-Vazquez, Paolo Nahuel Rubatto and Arnaldo Dubin
    Citation: Annals of Intensive Care 2014 4:39
  13. Even in developed countries, severe specific pregnancy complications may occur in the immediate postpartum period and require admission to the ICU. The characteristics and risk factors of acute renal failure (ARF...

    Authors: Marie Jonard, Anne-Sophie Ducloy-Bouthors, Eileen Boyle, Maryse Aucourt, Gaelle Gasan, Merce Jourdain, Virginie Mignaux, Nadia Tillouche and François Fourrier
    Citation: Annals of Intensive Care 2014 4:36
  14. In critically ill patients with pneumonia, accurate microorganism identification allows appropriate antibiotic treatment. In patients undergoing bronchoalveolar lavage (BAL), direct examination of the fluid us...

    Authors: Jean-Luc Baudel, Jacques Tankovic, Redouane Dahoumane, Fabrice Carrat, Arnaud Galbois, Hafid Ait-Oufella, Georges Offenstadt, Bertrand Guidet and Eric Maury
    Citation: Annals of Intensive Care 2014 4:35
  15. Healthcare-associated bloodstream infections are related to both increased antibiotic use and risk of adverse outcomes. An in-depth understanding of their epidemiology is essential to reduce occurrence and to ...

    Authors: Nick Culshaw, Guy Glover, Craig Whiteley, Katie Rowland, Duncan Wyncoll, Andrew Jones and Manu Shankar-Hari
    Citation: Annals of Intensive Care 2014 4:34
  16. The Lung Open Ventilation Study (LOV Study) compared a low tidal volume strategy with an experimental strategy combining low tidal volume, lung recruitment maneuvers, and higher plateau and positive end-expira...

    Authors: Sangeeta Mehta, Deborah J Cook, Yoanna Skrobik, John Muscedere, Claudio M Martin, Thomas E Stewart, Lisa D Burry, Qi Zhou and Maureen Meade
    Citation: Annals of Intensive Care 2014 4:33
  17. Guidelines on systemic corticosteroids in chronic obstructive pulmonary disease (COPD) exacerbation rely on studies that excluded patients requiring ventilatory support. Recent publication of studies including...

    Authors: Fekri Abroug, Islem Ouanes, Sarra Abroug, Fahmi Dachraoui, Saoussen Ben Abdallah, Zeineb Hammouda and Lamia Ouanes-Besbes
    Citation: Annals of Intensive Care 2014 4:32
  18. The decision of when to stop septic shock resuscitation is a critical but yet a relatively unexplored aspect of care. This is especially relevant since the risks of over-resuscitation with fluid overload or in...

    Authors: Glenn Hernandez, Cecilia Luengo, Alejandro Bruhn, Eduardo Kattan, Gilberto Friedman, Gustavo A Ospina-Tascon, Andrea Fuentealba, Ricardo Castro, Tomas Regueira, Carlos Romero, Can Ince and Jan Bakker
    Citation: Annals of Intensive Care 2014 4:30
  19. High-flow nasal cannula (HFNC) is a relatively new device for respiratory support. In pediatrics, HFNC use continues to increase as the system is easily set up and is well tolerated by patients. The use of nas...

    Authors: Christophe Milési, Mathilde Boubal, Aurélien Jacquot, Julien Baleine, Sabine Durand, Marti Pons Odena and Gilles Cambonie
    Citation: Annals of Intensive Care 2014 4:29
  20. Acute respiratory distress syndrome (ARDS) is characterised by diffuse alveolar damage and is frequently complicated by pulmonary hypertension (PH). Multiple factors may contribute to the development of PH in ...

    Authors: Donal Ryan, Stephen Frohlich and Paul McLoughlin
    Citation: Annals of Intensive Care 2014 4:28
  21. The features of early-phase acute respiratory distress syndrome (ARDS) are leakage of fluid into the extravascular space and impairment of its reabsorption, resulting in extravascular lung water (EVLW) accumul...

    Authors: Takashi Tagami, Toshiaki Nakamura, Shigeki Kushimoto, Ryoichi Tosa, Akihiro Watanabe, Tadashi Kaneko, Hidetada Fukushima, Hiroshi Rinka, Daisuke Kudo, Hideaki Uzu, Akira Murai, Makoto Takatori, Hiroo Izumino, Yoichi Kase, Ryutarou Seo, Hiroyuki Takahashi…
    Citation: Annals of Intensive Care 2014 4:27
  22. Thrombocytopenia is common in the intensive care unit. Potential mechanisms and etiologies behind this phenomenon are multiple and often entangled. We assessed the effect of a systematic approach, using routin...

    Authors: Nadiejda Antier, Jean-Pierre Quenot, Jean-Marc Doise, Robin Noel, Emmanuel Demaistre and Hervé Devilliers
    Citation: Annals of Intensive Care 2014 4:24
  23. In the later stages of circulatory shock, monitoring should help to avoid fluid overload. In this setting, volume expansion is ideally indicated only for patients in whom the cardiac index (CI) is expected to ...

    Authors: Thieme Souza Oliveira Nunes, Renata Teixeira Ladeira, Antônio Tonete Bafi, Luciano Cesar Pontes de Azevedo, Flavia Ribeiro Machado and Flávio Geraldo Rezende Freitas
    Citation: Annals of Intensive Care 2014 4:25
  24. High inspiratory oxygen concentrations are frequently administered in ventilated patients in the intensive care unit (ICU) but may induce lung injury and systemic toxicity. We compared beliefs and actual clini...

    Authors: Hendrik JF Helmerhorst, Marcus J Schultz, Peter HJ van der Voort, Robert J Bosman, Nicole P Juffermans, Evert de Jonge and David J van Westerloo
    Citation: Annals of Intensive Care 2014 4:23
  25. Prognostic abilities of medical parameters, which are scoring systems, measurements and biomarkers, are important for stratifying critically ill patients. Indocyanine green plasma disappearance (ICG-PDR) is an...

    Authors: Bernhard Zoller, Katharina Spanaus, Rahel Gerster, Mario Fasshauer, Paul A Stehberger, Stephanie Klinzing, Athanasios Vergopoulos, Arnold von Eckardstein and Markus Béchir
    Citation: Annals of Intensive Care 2014 4:19
  26. The death of a loved one is often an ordeal and a tragedy for those who witness it, as death is not merely the end of a life, but also the end of an existence, the loss of a unique individual who is special an...

    Authors: Cédric Daubin, Lise Haddad, Dominique Folscheid, Alexandre Boyer, Ludivine Chalumeau-Lemoine, Olivier Guisset, Philippe Hubert, Jérôme Pillot, René Robert and Didier Dreyfuss
    Citation: Annals of Intensive Care 2014 4:17
  27. Despite advances in supportive care, moderate-severe acute respiratory distress syndrome (ARDS) is associated with high mortality rates, and novel therapies to treat this condition are needed. Compelling pre-c...

    Authors: Kathleen D Liu, Jennifer G Wilson, Hanjing Zhuo, Lizette Caballero, Melanie L McMillan, Xiaohui Fang, Katherine Cosgrove, Carolyn S Calfee, Jae-Woo Lee, Kirsten N Kangelaris, Jeffrey E Gotts, Angela J Rogers, Joseph E Levitt, Jeanine P Wiener-Kronish, Kevin L Delucchi, Andrew D Leavitt…
    Citation: Annals of Intensive Care 2014 4:22
  28. Platelet activation and consumption are common in critically ill patients and are associated with poorer prognosis. Mean platelet volume is a simple surrogate for platelet activation, with higher MPV being ass...

    Authors: Fernando G Zampieri, Otavio T Ranzani, Viviane Sabatoski, Heraldo Possolo de Souza, Hermes Barbeiro, Luiz Monteiro Cruz da Neto, Marcelo Park and Fabiano Pinheiro da Silva
    Citation: Annals of Intensive Care 2014 4:20
  29. The influenza H1N1 epidemics in 2009 led a substantial number of people to develop severe acute respiratory distress syndrome and refractory hypoxemia. In these patients, extracorporeal membrane oxygenation wa...

    Authors: Christian Richard, Laurent Argaud, Alice Blet, Thierry Boulain, Laetitia Contentin, Agnès Dechartres, Jean-Marc Dejode, Laurence Donetti, Muriel Fartoukh, Dominique Fletcher, Khaldoun Kuteifan, Sigismond Lasocki, Jean-Michel Liet, Anne-Claire Lukaszewicz, Hervé Mal, Eric Maury…
    Citation: Annals of Intensive Care 2014 4:15
  30. Daily sedative interruption and intermittent sedation are effective in abbreviating the time on mechanical ventilation. Whether one is superior to the other has not yet been determined. Our aim was to compare ...

    Authors: Antonio Paulo Nassar Junior and Marcelo Park
    Citation: Annals of Intensive Care 2014 4:14
  31. The optimum dosage regimen for cotrimoxazole in the treatment of life threatening infections due to susceptible organisms encountered in critically ill patients is unclear despite decades of the drug’s use. Th...

    Authors: Glen R Brown
    Citation: Annals of Intensive Care 2014 4:13
  32. We studied a score for assessing basic transthoracic echocardiography (TTE) skills exhibited by residents who examined critically ill patients receiving mechanical ventilation.

    Authors: Mathieu Jozwiak, Xavier Monnet, Raphaël Cinotti, Fréderic Bontemps, Jean Reignier and Guillaume Belliard
    Citation: Annals of Intensive Care 2014 4:12
  33. Earlobe arterialized capillary blood gas analysis can be used to estimate arterial gas content and may be suitable for diagnosis and management of critically ill patients. However, its utility and applicabilit...

    Authors: Sergi Vaquer, Jordi Masip, Gisela Gili, Gemma Gomà, Joan Carles Oliva, Alexandre Frechette, Simon Evetts, Thais Russomano and Antonio Artigas
    Citation: Annals of Intensive Care 2014 4:11
  34. ICU patients frequently undergo chest radiographs (CXRs). The diagnostic and therapeutic efficacy of routine CXRs are now known to be low, but the discussion regarding specific indications for CXRs in critical...

    Authors: Martijn Tolsma, Tom A Rijpstra, Marcus J Schultz, Paul GH Mulder and Nardo JM van der Meer
    Citation: Annals of Intensive Care 2014 4:10
  35. Post-cardiac arrest hypocapnia/hypercapnia have been associated with poor neurological outcome. However, the impact of arterial carbon dioxide (CO2) derangements during the immediate post-resuscitation period fol...

    Authors: Brian W Roberts, J Hope Kilgannon, Michael E Chansky and Stephen Trzeciak
    Citation: Annals of Intensive Care 2014 4:9
  36. OptiScanner devices, continuous glucose monitoring devices that perform automated blood draws via a central venous catheter and create plasma through centrifugation, measure plasma glucose levels through mid-i...

    Authors: Roosmarijn TM van Hooijdonk, Tineke Winters, Johan C Fischer, Edmée C van Dongen-Lases, James S Krinsley, Jean-Charles Preiser and Marcus J Schultz
    Citation: Annals of Intensive Care 2014 4:8
  37. Longstanding concerns regarding end of life in the ICU led in France to the publication of guidelines, updated in 2009, that take into account the insights provided by a recent law (Leonetti’s law) regarding p...

    Authors: René Robert, Laurence Salomon, Lise Haddad, Jean-Pierre Graftieaux, Béatrice Eon and Didier Dreyfuss
    Citation: Annals of Intensive Care 2014 4:6
  38. The aim of this study was to determine the association between 25-hydroxyvitamin D (25-OHD) levels at the onset of critical illness and the development of acute lung injury/acute respiratory distress syndrome ...

    Authors: Nicolas Barnett, Zhiguo Zhao, Tatsuki Koyama, David R Janz, Chen-Yu Wang, Addison K May, Gordon R Bernard and Lorraine B Ware
    Citation: Annals of Intensive Care 2014 4:5
  39. The Lung Injury Score (LIS) remains a commonly utilized measure of lung injury severity though the additive value of LIS to predict ARDS outcomes over the recent Berlin definition of ARDS, which incorporates s...

    Authors: Kirsten Neudoerffer Kangelaris, Carolyn S Calfee, Addison K May, Hanjing Zhuo, Michael A Matthay and Lorraine B Ware
    Citation: Annals of Intensive Care 2014 4:4
  40. Data from previous studies indicate that optimal conditions for intubation are met 120 seconds after administration of 0.15 mg.kg-1 cisatracurium (ED95 × 3) following the induction of anesthesia. The aim of this ...

    Authors: Eric Dieye, Vincent Minville, Karim Asehnoune, Claude Conil, Bernard Georges, Pierre Cougot, Olivier Fourcade and Jean-Marie Conil
    Citation: Annals of Intensive Care 2014 4:3

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