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Articles
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Citation: Annals of Intensive Care 2020 10:156
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Effectiveness of corticosteroids for post-extubation stridor and extubation failure in pediatric patients: a systematic review and meta-analysis
While the results of previous meta-analyses have shown beneficial effects of corticosteroid therapy on post-extubation stridor and extubation failure in adults, these results might not be generalizable to chil...
Citation: Annals of Intensive Care 2020 10:155 -
Adsorption therapy in critically ill with septic shock and acute kidney injury: a retrospective and prospective cohort study
Haemoadsorption has been described as an effective way to control increased pro- and anti-inflammatory mediators (“cytokine storm”) in septic shock patients. No prospective or randomised clinical study has yet...
Citation: Annals of Intensive Care 2020 10:154 -
Physiologic responses to a staircase lung volume optimization maneuver in pediatric high-frequency oscillatory ventilation
Titration of the continuous distending pressure during a staircase incremental–decremental pressure lung volume optimization maneuver in children on high-frequency oscillatory ventilation is traditionally driv...
Citation: Annals of Intensive Care 2020 10:153 -
Retinal blood flow in critical illness and systemic disease: a review
Assessment and maintenance of end-organ perfusion are key to resuscitation in critical illness, although there are limited direct methods or proxy measures to assess cerebral perfusion. Novel non-invasive meth...
Citation: Annals of Intensive Care 2020 10:152 -
Rescue therapy with inhaled nitric oxide and almitrine in COVID-19 patients with severe acute respiratory distress syndrome
In COVID-19 patients with severe acute respiratory distress syndrome (ARDS), the relatively preserved respiratory system compliance despite severe hypoxemia, with specific pulmonary vascular dysfunction, sugge...
Citation: Annals of Intensive Care 2020 10:151 -
Effects of capillary refill time-vs. lactate-targeted fluid resuscitation on regional, microcirculatory and hypoxia-related perfusion parameters in septic shock: a randomized controlled trial
Persistent hyperlactatemia has been considered as a signal of tissue hypoperfusion in septic shock patients, but multiple non-hypoperfusion-related pathogenic mechanisms could be involved. Therefore, pursuing ...
Citation: Annals of Intensive Care 2020 10:150 -
Impact of systematic screening for AmpC-hyperproducing Enterobacterales intestinal carriage in intensive care unit patients
Empirical antimicrobial therapy (EAT) is a challenge for community-acquired, hospital-acquired and ventilator-associated pneumonia, particularly in the context of the increasing occurrence of third-generation ...
Citation: Annals of Intensive Care 2020 10:149 -
Irrespective of the degree of hyperlactatemia, similar lactate levels were associated with a lower mortality rate in metformin users compared with non-users: beware of confounders!
Citation: Annals of Intensive Care 2020 10:148 -
Comment on “Respiratory mechanics and gas exchanges in the early course of COVID-19 ARDS: a hypothesis-generating study”
Citation: Annals of Intensive Care 2020 10:147 -
Acute respiratory failure in immunocompromised patients: outcome and clinical features according to neutropenia status
The impact of neutropenia in critically ill immunocompromised patients admitted in a context of acute respiratory failure (ARF) remains uncertain. The primary objective was to assess the prognostic impact of n...
Citation: Annals of Intensive Care 2020 10:146 -
Sepsis and septic shock in France: incidences, outcomes and costs of care
Sepsis is one of the leading causes of death worldwide. The associated incidence, mortality and trends do not differ greatly between documented reports. The purpose of this study was to provide an in-depth des...
Citation: Annals of Intensive Care 2020 10:145 -
Patient–ventilator asynchrony in acute brain-injured patients: a prospective observational study
Patient–ventilator asynchrony is common in mechanically ventilated patients and may be related to adverse outcomes. Few studies have reported the occurrence of asynchrony in brain-injured patients. We aimed to...
Citation: Annals of Intensive Care 2020 10:144 -
Immune-related adverse events: a retrospective look into the future of oncology in the intensive care unit
Immune checkpoint inhibitors have reshaped the standard of care in oncology. However, they have been associated with potentially life-threatening immune-related adverse events. With the growing indications of ...
Citation: Annals of Intensive Care 2020 10:143 -
Epidemiology, clinical characteristics, and outcome of candidemia in critically ill patients in Germany: a single-center retrospective 10-year analysis
Despite advances in the management of bloodstream infections (BSI) caused by Candida spp., the mortality still remains high in critically ill patients. The worldwide epidemiology of yeast-related BSI is subject t...
Citation: Annals of Intensive Care 2020 10:142 -
Biased and unbiased estimation of the average length of stay in intensive care units in the Covid-19 pandemic
The average length of stay (LOS) in the intensive care unit (ICU_ALOS) is a helpful parameter summarizing critical bed occupancy. During the outbreak of a novel virus, estimating early a reliable ICU_ALOS esti...
Citation: Annals of Intensive Care 2020 10:135 -
Tigecycline pharmacokinetics in critically ill patients on renal replacement therapy: possible warnings and potential perspectives for the research agenda
Citation: Annals of Intensive Care 2020 10:141 -
Response to Damiani and colleagues
Citation: Annals of Intensive Care 2020 10:140 -
High doses of tigecycline are associated with satisfactory plasmatic and pulmonary concentrations for the treatment of severe infections due to fully susceptible bacteria: do we need even higher doses in patients under CRRT?
Citation: Annals of Intensive Care 2020 10:139 -
Persistent swallowing disorders after extubation in mechanically ventilated patients in ICU: a two-center prospective study
Persistent swallowing disorders (SD) are non-pulmonary complications of mechanical ventilation (MV). However, there are few clinical studies on persistent SD in critically ill patients undergoing tracheal intu...
Citation: Annals of Intensive Care 2020 10:138 -
pCLIF-SOFA is a reliable outcome prognostication score of critically ill children with cirrhosis: an ESPNIC multicentre study
Data on outcome of critically ill children with cirrhosis are scarce. We aimed to evaluate the prognostic accuracy of sequential organs scoring systems in children with cirrhosis admitted to Paediatric Intensi...
Citation: Annals of Intensive Care 2020 10:137 -
Treatment variables associated with outcome in emergency department patients with suspected sepsis
Early treatment is advocated in the management of patients with suspected sepsis in the emergency department (ED). We sought to understand the association between the ED treatments and outcome in patients admi...
Citation: Annals of Intensive Care 2020 10:136 -
COVID-19: scientific reasoning, pragmatism and emotional bias
Citation: Annals of Intensive Care 2020 10:134 -
Use of critical care resources during the first 2 weeks (February 24–March 8, 2020) of the Covid-19 outbreak in Italy
A Covid-19 outbreak developed in Lombardy, Veneto and Emilia-Romagna (Italy) at the end of February 2020. Fear of an imminent saturation of available ICU beds generated the notion that rationing of intensive c...
Citation: Annals of Intensive Care 2020 10:133 -
Best-practice IgM- and IgA-enriched immunoglobulin use in patients with sepsis
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Despite treatment being in line with current guidelines, mortality remains high in those with septic shock. I...
Citation: Annals of Intensive Care 2020 10:132 -
Characteristics and outcomes of acute respiratory distress syndrome related to COVID-19 in Belgian and French intensive care units according to antiviral strategies: the COVADIS multicentre observational study
Limited data are available regarding antiviral therapy efficacy in most severe patients under mechanical ventilation for Covid-19-related acute respiratory distress syndrome (ARDS).
Citation: Annals of Intensive Care 2020 10:131 -
Intra-abdominal hypertension and abdominal compartment syndrome in patients admitted to the ICU
Intra-abdominal hypertension is frequently present in critically ill patients and is an independent predictor for mortality. Risk factors for intra-abdominal hypertension and abdominal compartment syndrome hav...
Citation: Annals of Intensive Care 2020 10:130 -
Transpulmonary pressures in obese and non-obese COVID-19 ARDS
Data on respiratory mechanics of COVID-19 ARDS patients are scarce. Respiratory mechanics and response to positive expiratory pressure (PEEP) may be different in obese and non-obese patients.
Citation: Annals of Intensive Care 2020 10:129 -
Early mechanical ventilation in patients with Guillain-Barré syndrome at high risk of respiratory failure: a randomized trial
About 30% of patients with Guillain-Barré syndrome become ventilator dependent, of whom roughly 75% develop pneumonia. This trial aimed at assessing the impact of early mechanical ventilation (EMV) on pneumoni...
Citation: Annals of Intensive Care 2020 10:128 -
Vitamins as adjunctive treatment for coronavirus disease!
Citation: Annals of Intensive Care 2020 10:127 -
Physiological effects of adding ECCO2R to invasive mechanical ventilation for COPD exacerbations
Extracorporeal CO2 removal (ECCO2R) could be a valuable additional modality for invasive mechanical ventilation (IMV) in COPD patients suffering from severe acute exacerbation (AE). We aimed to evaluate in such p...
Citation: Annals of Intensive Care 2020 10:126 -
Surgical mask on top of high-flow nasal cannula improves oxygenation in critically ill COVID-19 patients with hypoxemic respiratory failure
Critically ill patients admitted in ICU because of COVID-19 infection display severe hypoxemic respiratory failure. The Surviving Sepsis Campaign recommends oxygenation through high-flow nasal cannula over non...
Citation: Annals of Intensive Care 2020 10:125 -
Pulmonary embolism in patients with coronavirus disease-2019 (COVID-19) pneumonia: a narrative review
Preliminary reports have described significant procoagulant events in patients with coronavirus disease-2019 (COVID-19), including life-threatening pulmonary embolism (PE).
Citation: Annals of Intensive Care 2020 10:124 -
Respiratory virus-associated infections in HIV-infected adults admitted to the intensive care unit for acute respiratory failure: a 6-year bicenter retrospective study (HIV-VIR study)
Acute respiratory failure is the main reason for admission to the intensive care unit (ICU) in HIV-infected adults. There is little data about the epidemiology of respiratory viruses in this population.
Citation: Annals of Intensive Care 2020 10:123 -
A preliminary study of intensivist-performed DVT ultrasound screening in trauma ICU patients (APSIT Study)
Multiple screening Duplex ultrasound scans (DUS) are performed in trauma patients at high risk of deep vein thrombosis (DVT) in the intensive care unit (ICU). Intensive care physician performed compression ult...
Citation: Annals of Intensive Care 2020 10:122 -
Potential risks in using midodrine for persistent hypotension after cardiac surgery: a comparative cohort study
Persistent hypotension is a frequent complication after cardiac surgery with cardiopulmonary bypass (CPB). Midodrine, an orally administered alpha agonist, could potentially reduce intravenous vasopressor use ...
Citation: Annals of Intensive Care 2020 10:121 -
Ultrasonographic assessment of parasternal intercostal muscles during mechanical ventilation
Although mechanical ventilation is a lifesaving treatment, abundant evidence indicates that its prolonged use (1 week or more) promotes respiratory muscle weakness due to both contractile dysfunction and atrop...
Citation: Annals of Intensive Care 2020 10:120 -
Bacterial and viral co-infections in patients with severe SARS-CoV-2 pneumonia admitted to a French ICU
Data on the prevalence of bacterial and viral co-infections among patients admitted to the ICU for acute respiratory failure related to SARS-CoV-2 pneumonia are lacking. We aimed to assess the rate of bacteria...
Citation: Annals of Intensive Care 2020 10:119 -
Expert consensus-based clinical practice guidelines management of intravascular catheters in the intensive care unit
The French Society of Intensive Care Medicine (SRLF), jointly with the French-Speaking Group of Paediatric Emergency Rooms and Intensive Care Units (GFRUP) and the French-Speaking Association of Paediatric Sur...
Citation: Annals of Intensive Care 2020 10:118 -
Acute kidney injury in patients with SARS-CoV-2 infection
Acute Kidney Injury (AKI) is a frequent complication of severe SARS-CoV-2 infection. Multiple mechanisms are involved in COVID-19-associated AKI, from direct viral infection and secondary inflammation to compl...
Citation: Annals of Intensive Care 2020 10:117 -
Epidural analgesia in ICU chest trauma patients with fractured ribs: retrospective study of pain control and intubation requirements
Nonintubated chest trauma patients with fractured ribs admitted to the intensive care unit (ICU) are at risk for complications and may require invasive ventilation at some point. Effective pain control is esse...
Citation: Annals of Intensive Care 2020 10:116 -
The impact of critical illness on the expiratory muscles and the diaphragm assessed by ultrasound in mechanical ventilated children
Critical illness has detrimental effects on the diaphragm, but the impact of critical illness on other major muscles of the respiratory pump has been largely neglected. This study aimed to determine the impact...
Citation: Annals of Intensive Care 2020 10:115 -
A lactate-targeted resuscitation strategy may be associated with higher mortality in patients with septic shock and normal capillary refill time: a post hoc analysis of the ANDROMEDA-SHOCK study
Capillary refill time (CRT) may improve more rapidly than lactate in response to increments in systemic flow. Therefore, it can be assessed more frequently during septic shock (SS) resuscitation. Hyperlactatem...
Citation: Annals of Intensive Care 2020 10:114 -
Prognostic performance of endothelial biomarkers to early predict clinical deterioration of patients with suspected bacterial infection and sepsis admitted to the emergency department
The objective of this study was to evaluate the ability of endothelial biomarkers to early predict clinical deterioration of patients admitted to the emergency department (ED) with a suspected sepsis. This was...
Citation: Annals of Intensive Care 2020 10:113 -
Gasping during refractory out-of-hospital cardiac arrest is a prognostic marker for favourable neurological outcome following extracorporeal cardiopulmonary resuscitation: a retrospective study
Gasping during cardiac arrest is associated with favourable neurological outcomes for out-of-hospital cardiac arrest. Moreover, while extracorporeal cardiopulmonary resuscitation (ECPR) performed for refractor...
Citation: Annals of Intensive Care 2020 10:112 -
Mortality and morbidity of low-grade red blood cell transfusions in septic patients: a propensity score-matched observational study of a liberal transfusion strategy
Red blood cell (RBC) transfusions are associated with risks including immunological reactions and volume overload. Current guidelines suggest a restrictive transfusion strategy in most patients with sepsis but...
Citation: Annals of Intensive Care 2020 10:111 -
Symptoms of burnout in intensive care unit specialists facing the COVID-19 outbreak
The COVID-19 pandemic has resulted in an unprecedented healthcare crisis with a high prevalence of psychological distress in healthcare providers. We sought to document the prevalence of burnout syndrome among...
Citation: Annals of Intensive Care 2020 10:110 -
Diastolic shock index (DSI) works… and it could be a quite useful tool
Citation: Annals of Intensive Care 2020 10:109 -
Is hypoxemia explained by intracardiac or intrapulmonary shunt in COVID-19-related acute respiratory distress syndrome?
Hypoxemia is the main feature of COVID-19-related acute respiratory distress syndrome (C-ARDS), but its underlying mechanisms are debated, especially in patients with low respiratory system elastance (Ers). We...
Citation: Annals of Intensive Care 2020 10:108 -
Progression of regional lung strain and heterogeneity in lung injury: assessing the evolution under spontaneous breathing and mechanical ventilation
Protective mechanical ventilation (MV) aims at limiting global lung deformation and has been associated with better clinical outcomes in acute respiratory distress syndrome (ARDS) patients. In ARDS lungs witho...
Citation: Annals of Intensive Care 2020 10:107
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- ISSN: 2110-5820 (electronic)