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  1. Prone positioning is currently applied in time-limited daily sessions up to 24 h which determines that most patients require several sessions. Although longer prone sessions have been reported, there is scarce...

    Authors: Rodrigo A. Cornejo, Jorge Montoya, Abraham I. J. Gajardo, Jerónimo Graf, Leyla Alegría, Romyna Baghetti, Anita Irarrázaval, César Santis, Nicolás Pavez, Sofía Leighton, Vinko Tomicic, Daniel Morales, Carolina Ruiz, Pablo Navarrete, Patricio Vargas, Roberto Gálvez…
    Citation: Annals of Intensive Care 2022 12:109
  2. Frailty and delirium are prevalent among older adults admitted to the intensive care unit (ICU) and associated with adverse outcomes; however, their relationships have not been extensively explored. This study...

    Authors: Berhe W. Sahle, David Pilcher, Edward Litton, Richard Ofori-Asenso, Karlheinz Peter, James McFadyen and Tracey Bucknall
    Citation: Annals of Intensive Care 2022 12:108
  3. β-lactams are the main antibiotics used against wild-type AmpC-producing Enterobacterales (wtAE). However, they may fail or select AmpC-overproducing mutants. Our aim was to assess factors associated with clin...

    Authors: Roman Mounier, Ronan Le Guen, Paul-Louis Woerther, Mathieu Nacher, Clément Bonnefon, Nicolas Mongardon, Olivier Langeron, Eric Levesque, Séverine Couffin, Stéphanie Houcke, Michel Wolff, Ariane Roujansky, Caroline Schimpf, Armand Mekontso Dessap, Fabrice Cook, Keyvan Razazi…
    Citation: Annals of Intensive Care 2022 12:107
  4. Since the response to lung recruitment varies greatly among patients receiving mechanical ventilation, lung recruitability should be assessed before recruitment maneuvers. The pressure–volume curve (PV curve) ...

    Authors: Ryuichi Nakayama, Naofumi Bunya, Shinshu Katayama, Yuya Goto, Yusuke Iwamoto, Kenshiro Wada, Keishi Ogura, Naoya Yama, Shintaro Takatsuka, Masumi Kishimoto, Kanako Takahashi, Ryuichiro Kakizaki, Keigo Sawamoto, Shuji Uemura, Keisuke Harada and Eichi Narimatsu
    Citation: Annals of Intensive Care 2022 12:106
  5. Extracorporeal blood purification (EBP) treatments may be used in patients with sepsis and related conditions to mitigate toxic systemic inflammation, prevent or reverse vital organ injury, and improve outcome...

    Authors: James Matson, Paul Lange, Patrick M. Honore and Kevin K. Chung
    Citation: Annals of Intensive Care 2022 12:105
  6. Right ventricular (RV) dysfunction has been commonly reported in patients with Coronavirus disease 2019 (COVID-19), and is associated with mortality in mixed cohorts of patients requiring and not requiring inv...

    Authors: James McErlane, Philip McCall, Jennifer Willder, Colin Berry and Ben Shelley
    Citation: Annals of Intensive Care 2022 12:104
  7. Clinicians monitor mechanical ventilatory support using airway pressures—primarily the plateau and driving pressure, which are considered by many to determine the safety of the applied tidal volume. These airw...

    Authors: John Selickman and John J. Marini
    Citation: Annals of Intensive Care 2022 12:103
  8. Dexamethasone is recommended for COVID-19 patients who require oxygen therapy. However, its effectiveness in reducing mortality and intubation, and its safety, remain debated. We aimed to investigate whether d...

    Authors: Matthieu Raymond, Aurélie Le Thuaut, Pierre Asfar, Cédric Darreau, Florian Reizine, Gwenhaël Colin, Charly Dano, Julien Lorber, Baptiste Hourmant, Agathe Delbove, Aurélien Frérou, Jean Morin, Pierre Yves Egreteau, Philippe Seguin, Jean Reignier, Jean-Baptiste Lascarrou…
    Citation: Annals of Intensive Care 2022 12:102
  9. Etoposide remains the cornerstone of symptomatic management of critically ill patients with secondary hemophagocytic syndrome (sHS). Risk of healthcare-associated infections (HAIs) in this setting with etoposi...

    Authors: Thibault Dupont, Michael Darmon, Eric Mariotte, Virginie Lemiale, Jehane Fadlallah, Adrien Mirouse, Lara Zafrani, Elie Azoulay and Sandrine Valade
    Citation: Annals of Intensive Care 2022 12:101
  10. Fluid creep, including fluids administered as drug diluents and for the maintenance of catheter patency, is the major source of fluid intake in critically ill patients. Although hypoxemia may lead to fluid res...

    Authors: Masaaki Sakuraya, Shodai Yoshihiro, Kazuto Onozuka, Akihiro Takaba, Hideto Yasuda, Nobuaki Shime, Yuki Kotani, Yuki Kishihara, Natsuki Kondo, Kosuke Sekine and Keita Morikane
    Citation: Annals of Intensive Care 2022 12:100
  11. For mechanically ventilated critically ill COVID-19 patients, prone positioning has quickly become an important treatment strategy, however, prone positioning is labor intensive and comes with potential advers...

    Authors: Tariq A. Dam, Luca F. Roggeveen, Fuda van Diggelen, Lucas M. Fleuren, Ameet R. Jagesar, Martijn Otten, Heder J. de Vries, Diederik Gommers, Olaf L. Cremer, Rob J. Bosman, Sander Rigter, Evert-Jan Wils, Tim Frenzel, Dave A. Dongelmans, Remko de Jong, Marco A. A. Peters…
    Citation: Annals of Intensive Care 2022 12:99
  12. Patients with acute pancreatitis (AP) often require ICU admission, especially when signs of multiorgan failure are present, a condition that defines AP as severe. This disease is characterized by a massive pancre...

    Authors: Andrea Crosignani, Stefano Spina, Francesco Marrazzo, Stefania Cimbanassi, Manu L. N. G. Malbrain, Niels Van Regenemortel, Roberto Fumagalli and Thomas Langer
    Citation: Annals of Intensive Care 2022 12:98
  13. Outcomes of postresuscitation shock after cardiac arrest can be affected by targeted temperature management (TTM). A post hoc analysis of the “TTM1 trial” suggested higher mortality with hypothermia at 33 °C. ...

    Authors: Ines Ziriat, Aurélie Le Thuaut, Gwenhael Colin, Hamid Merdji, Guillaume Grillet, Patrick Girardie, Bertrand Souweine, Pierre-François Dequin, Thierry Boulain, Jean-Pierre Frat, Pierre Asfar, Bruno Francois, Mickael Landais, Gaëtan Plantefeve, Jean-Pierre Quenot, Jean-Charles Chakarian…
    Citation: Annals of Intensive Care 2022 12:96
  14. Identifying patients who will receive renal replacement therapy (RRT) during intensive care unit (ICU) stay is a major challenge for intensivists. The objective of this study was to evaluate the performance of...

    Authors: Alexandre Sitbon, Michael Darmon, Guillaume Geri, Paul Jaubert, Pauline Lamouche-Wilquin, Clément Monet, Lucie Le Fèvre, Marie Baron, Marie-Line Harlay, Côme Bureau, Olivier Joannes-Boyau, Claire Dupuis, Damien Contou, Virginie Lemiale, Marie Simon, Christophe Vinsonneau…
    Citation: Annals of Intensive Care 2022 12:95
  15. Helmet noninvasive support may provide advantages over other noninvasive oxygenation strategies in the management of acute hypoxemic respiratory failure. In this narrative review based on a systematic search o...

    Authors: Melania Cesarano, Domenico Luca Grieco, Teresa Michi, Laveena Munshi, Luca S. Menga, Luca Delle Cese, Ersilia Ruggiero, Tommaso Rosà, Daniele Natalini, Michael C. Sklar, Salvatore L. Cutuli, Filippo Bongiovanni, Gennaro De Pascale, Bruno L. Ferreyro, Ewan C. Goligher and Massimo Antonelli
    Citation: Annals of Intensive Care 2022 12:94
  16. Venoarterial extracorporeal membrane oxygenation (va-ECMO) is an advanced life support for critically ill patients with refractory cardiogenic shock. This temporary support bridges time for recovery, permanent...

    Authors: Sasa Rajsic, Benedikt Treml, Dragana Jadzic, Robert Breitkopf, Christoph Oberleitner, Marina Popovic Krneta and Zoran Bukumiric
    Citation: Annals of Intensive Care 2022 12:93
  17. Right ventricular (RV) dysfunction is common in critically ill patients and is associated with poor outcomes. RV function is usually evaluated by Tricuspid Annular Plane Systolic Excursion (TAPSE) which can be...

    Authors: Madelon E. Vos, Eline G. M. Cox, Maaike R. Schagen, Bart Hiemstra, Adrian Wong, Jacqueline Koeze, Iwan C. C. van der Horst and Renske Wiersema
    Citation: Annals of Intensive Care 2022 12:92
  18. The aim of this study was to compare the effectiveness and safety of ultrasound-guided out-of-plane internal jugular vein (OOP-IJV) and in-plane supraclavicular subclavian vein (IP-SSCV) catheterization in adu...

    Authors: Becem Trabelsi, Zied Hajjej, Dhouha Drira, Azza Yedes, Iheb Labbene, Mustapha Ferjani and Mechaal Ben Ali
    Citation: Annals of Intensive Care 2022 12:91
  19. Cefoxitin is active against some extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-PE), but has not been evaluated so far in the intensive care unit (ICU) settings. Data upon its pharmacokinetics ...

    Authors: Paul Chabert, Judith Provoost, Sabine Cohen, Céline Dupieux-Chabert, Laurent Bitker, Tristan Ferry, Sylvain Goutelle and Jean-Christophe Richard
    Citation: Annals of Intensive Care 2022 12:90
  20. Bedside assessment of low levels of inspiratory effort, which are probably insufficient to prevent muscle atrophy, is challenging. The flow index, which is derived from the analysis of the inspiratory portion ...

    Authors: Ming-Yue Miao, Wei Chen, Yi-Min Zhou, Ran Gao, De-Jing Song, Shu-Peng Wang, Yan-Lin Yang, Linlin Zhang and Jian-Xin Zhou
    Citation: Annals of Intensive Care 2022 12:89
  21. Augmented renal clearance (ARC) remains poorly evaluated in ICU. The objective of this study is to provide a full description of ARC in ICU including prevalence, evolution profile, risk factors and outcomes.

    Authors: Alexandre Egea, Claire Dupuis, Etienne de Montmollin, Paul-Henry Wicky, Juliette Patrier, Pierre Jaquet, Lucie Lefèvre, Fabrice Sinnah, Mehdi Marzouk, Romain Sonneville, Lila Bouadma, Bertrand Souweine and Jean-François Timsit
    Citation: Annals of Intensive Care 2022 12:88
  22. Lung reactivations of Herpesviridae, herpes simplex virus (HSV) and cytomegalovirus (CMV) have been reported in COVID-19 patients. Whether or not those viral reactivations are more frequent than in other patients...

    Authors: Charles-Edouard Luyt, Sonia Burrel, David Mokrani, Marc Pineton de Chambrun, Domitille Luyt, Juliette Chommeloux, Vincent Guiraud, Nicolas Bréchot, Matthieu Schmidt, Guillaume Hekimian, Alain Combes and David Boutolleau
    Citation: Annals of Intensive Care 2022 12:87
  23. While antibiotic therapy is advocated to improve outcomes in acute exacerbation of chronic obstructive pulmonary disease (AECOPD) whenever mechanical ventilation is required, the evidence relies on small studi...

    Authors: G. Deniel, M. Cour, L. Argaud, J. C. Richard and L. Bitker
    Citation: Annals of Intensive Care 2022 12:86
  24. Among strategies that aimed to prevent acquired infections (AIs), selective decontamination regimens have been poorly studied in the COVID-19 setting. We assessed the impact of a multiple-site decontamination ...

    Authors: Nicolas Massart, Florian Reizine, Pierre Fillatre, Philippe Seguin, Béatrice La Combe, Aurélien Frerou, Pierre-Yves Egreteau, Baptiste Hourmant, Pierre Kergoat, Julien Lorber, Jerome Souchard, Emmanuel Canet, Guillaume Rieul, Yannick Fedun, Agathe Delbove and Christophe Camus
    Citation: Annals of Intensive Care 2022 12:84
  25. Authors: Michelle S. Chew, Saga Jansson, Meriam Åström Aneq and Jan Engvall
    Citation: Annals of Intensive Care 2022 12:83

    The original article was published in Annals of Intensive Care 2022 12:82

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2022 12:82

    The Research to this article has been published in Annals of Intensive Care 2022 12:56

  26. Authors: Minesh Chotalia, Mansoor N. Bangash, Jaimin M. Patel and Dhruv Parekh
    Citation: Annals of Intensive Care 2022 12:82

    The original article was published in Annals of Intensive Care 2022 12:56

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2022 12:83

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2022 12:83

  27. Dexmedetomidine is widely used in patients with sepsis. However, its effect on septic patients remains controversial. The objective of this study was to summarize all randomized controlled trials (RCTs) examin...

    Authors: Ting Zhang, Qimin Mei, Shabai Dai, Yecheng Liu and Huadong Zhu
    Citation: Annals of Intensive Care 2022 12:81
  28. Acute fulminant myocarditis in children is associated with elevated mortality and morbidity with few advances in its medical management. Here we report a preliminary experience of children treated with IL-1 re...

    Authors: Louise Maunier, Ramy Charbel, Virginie Lambert and Pierre Tissières
    Citation: Annals of Intensive Care 2022 12:80
  29. Long-term pulmonary sequelae, including 1-year thoracic computed tomography (CT) sequelae of paediatric acute respiratory distress syndrome (ARDS) remain unknown. The purpose of the study was to determine pulm...

    Authors: Véronique Nève, Ahmed Sadik, Laurent Petyt, Stéphane Dauger, Ahmed Kheniche, André Denjean, Pierre-Louis Léger, François Chalard, Michèle Boulé, Etienne Javouhey, Philippe Reix, Isabelle Canterino, Valérie Deken, Régis Matran, Stéphane Leteurtre and Francis Leclerc
    Citation: Annals of Intensive Care 2022 12:79
  30. In patients with septic shock, the impact of the mean arterial pressure (MAP) target on the course of mottling remains uncertain. In this post hoc analysis of the SEPSISPAM trial, we investigated whether a low...

    Authors: Nicolas Fage, Julien Demiselle, Valérie Seegers, Hamid Merdji, Fabien Grelon, Bruno Mégarbane, Nadia Anguel, Jean-Paul Mira, Pierre-François Dequin, Soizic Gergaud, Nicolas Weiss, François Legay, Yves Le Tulzo, Marie Conrad, Remi Coudroy, Frédéric Gonzalez…
    Citation: Annals of Intensive Care 2022 12:78
  31. Several scoring systems have been used to predict short-term outcome in patients with out-of-hospital cardiac arrest (OHCA), including the disease-specific OHCA and CAHP (Cardiac Arrest Hospital Prognosis) sco...

    Authors: René Blatter, Simon A. Amacher, Chantal Bohren, Christoph Becker, Katharina Beck, Sebastian Gross, Kai Tisljar, Raoul Sutter, Stephan Marsch and Sabina Hunziker
    Citation: Annals of Intensive Care 2022 12:77
  32. Although multiple individual immune parameters have been demonstrated to predict the occurrence of secondary infection after critical illness, significant questions remain with regards to the selection, timing...

    Authors: Jan-Alexis Tremblay, Florian Peron, Louis Kreitmann, Julien Textoris, Karen Brengel-Pesce, Anne-Claire Lukaszewicz, Laurence Quemeneur, Christophe Vedrine, Lionel K. Tan, Fabienne Venet, Thomas Rimmele and Guillaume Monneret
    Citation: Annals of Intensive Care 2022 12:76
  33. CAR-T cell (chimeric antigen receptor T) therapy has emerged as an effective treatment of refractory hematological malignancies. Intensive care management is intrinsic to CAR-T cell therapy. We aim to describe...

    Authors: Sandrine Valade, Michael Darmon, Lara Zafrani, Eric Mariotte, Virginie Lemiale, Swann Bredin, Guillaume Dumas, Nicolas Boissel, Florence Rabian, André Baruchel, Isabelle Madelaine, Jérôme Larghero, Anne Brignier, Etienne Lengliné, Stéphanie Harel, Bertrand Arnulf…
    Citation: Annals of Intensive Care 2022 12:75
  34. Capillary refill time (CRT) is a valuable tool for triage and to guide resuscitation. However, little is known about CRT kinetics after fluid infusion.

    Authors: Lisa Raia, Paul Gabarre, Vincent Bonny, Tomas Urbina, Louai Missri, Pierre-Yves Boelle, Jean-Luc Baudel, Bertrand Guidet, Eric Maury, Jeremie Joffre and Hafid Ait-Oufella
    Citation: Annals of Intensive Care 2022 12:74
  35. Tracheostomy is often performed in the intensive care unit (ICU) when mechanical ventilation (MV) weaning is prolonged to facilitate daily care. Tracheostomized patients require important healthcare resources ...

    Authors: Davy Cabrio, Timothée Vesin, Ermes Lupieri, Hélène Messet, Kishore Sandu and Lise Piquilloud
    Citation: Annals of Intensive Care 2022 12:73
  36. The mortality of extensively drug-resistant Gram-negative (XDR GN) bacilli-induced ventilator-associated pneumonia (VAP) is extremely high. The purpose of this study was to compare the efficacy and safety of i...

    Authors: Jiao Liu, Min Shao, Qianghong Xu, Fen Liu, Xiaojun Pan, Jianfeng Wu, Lihong Xiong, Yueming Wu, Mi Tian, Jianying Yao, Sisi Huang, Lidi Zhang, Yizhu Chen, Sheng Zhang, Zhenliang Wen, Hangxiang Du…
    Citation: Annals of Intensive Care 2022 12:72
  37. Recent guidelines advocate a step-up approach for managing suspected infected pancreatic necrosis (IPN) during acute pancreatitis. Nearly half the patients require secondary necrosectomy after catheter drainag...

    Authors: Charlotte Garret, Marion Douillard, Arthur David, Morgane Péré, Lucille Quenehervé, Ludivine Legros, Isabelle Archambeaud, Frédéric Douane, Marc Lerhun, Nicolas Regenet, Jerome Gournay, Emmanuel Coron, Eric Frampas and Jean Reignier
    Citation: Annals of Intensive Care 2022 12:71
  38. Acute kidney injury (AKI) is a frequent complication in patients with severe respiratory failure receiving extracorporeal membrane oxygenation (ECMO). However, little is known of long-term kidney function in E...

    Authors: Nuttha Lumlertgul, Rebeka Wright, Gareth Hutson, Jovana Kusic Milicevic, Georgios Vlachopanos, Ken Cheah Hooi Lee, Leah Pirondini, John Gregson, Barnaby Sanderson, Richard Leach, Luigi Camporota, Nicholas A. Barrett and Marlies Ostermann
    Citation: Annals of Intensive Care 2022 12:70
  39. The optimal early mean arterial pressure (MAP) level in terms of renal function remains to be established in patients with out-of-hospital cardiac arrest (OHCA). We aimed to evaluate the association between ea...

    Authors: Vincent Dupont, Anne-Sophie Bonnet-Lebrun, Alice Boileve, Julien Charpentier, Jean-Paul Mira, Guillaume Geri, Alain Cariou and Mathieu Jozwiak
    Citation: Annals of Intensive Care 2022 12:69
  40. Tracheal intubation and invasive mechanical ventilation initiation is a procedure at high risk for arterial hypotension in intensive care unit. However, little is known about the relationship between pre-exist...

    Authors: Vincent Dubée, Geoffroy Hariri, Jérémie Joffre, Julien Hagry, Lisa Raia, Vincent Bonny, Paul Gabarre, Sebastien Ehrminger, Naike Bigé, Jean-Luc Baudel, Bertrand Guidet, Eric Maury, Guillaume Dumas and Hafid Ait-Oufella
    Citation: Annals of Intensive Care 2022 12:68
  41. Authors: Zujin Luo, Zhixin Cao and Chen Wang
    Citation: Annals of Intensive Care 2022 12:67

    The original article was published in Annals of Intensive Care 2022 12:66

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2022 12:66

    The Research to this article has been published in Annals of Intensive Care 2022 12:41

  42. Authors: Radhouane Toumi, Khaoula Meddeb and Mohamed Boussarsar
    Citation: Annals of Intensive Care 2022 12:66

    The original article was published in Annals of Intensive Care 2022 12:41

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2022 12:67

  43. Little is known about the impact of hospital trajectory on survival and functional decline of older critically ill patients. We evaluate 6-month outcomes after admission to: intensive care units (ICU), interme...

    Authors: Sara Thietart, Ariane Boumendil, Dominique Pateron, Bertrand Guidet and Hélène Vallet
    Citation: Annals of Intensive Care 2022 12:65
  44. The long-term clinical status of coronavirus disease 2019 (COVID-19) in recovered patients remains largely unknown. This prospective cohort study evaluated clinical status of COVID-19 and explored the associated ...

    Authors: Dapeng Li, Xuejiao Liao, Zhenghua Ma, Lina Zhang, Jingke Dong, Guoqin Zheng, Mei Zi, Wujian Peng, Lanlan Wei, Zhiyan Li, Yingjun Kong, Lifei Wang, Dongjing Liu, Fang Wang, Qing He, Guobao Li…
    Citation: Annals of Intensive Care 2022 12:64
  45. Authors: Fredric Parenmark and Sten M. Walther
    Citation: Annals of Intensive Care 2022 12:63

    The original article was published in Annals of Intensive Care 2022 12:60

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2022 12:60

    The Research to this article has been published in Annals of Intensive Care 2022 12:31

  46. Whether early fluid accumulation is a risk factor for adverse renal outcomes in septic intensive care unit (ICU) patients remains uncertain. We assessed the association between cumulative fluid balance and maj...

    Authors: Alessandro Mele, Emanuele Cerminara, Henrike Häbel, Borja Rodriguez-Galvez, Anders Oldner, David Nelson, Johannes Gårdh, Ragnar Thobaben, Sandra Jonmarker, Maria Cronhjort, Jacob Hollenberg and Johan Mårtensson
    Citation: Annals of Intensive Care 2022 12:62
  47. Excess exposure to norepinephrine can compromise microcirculation and organ function. We aimed to assess the association between norepinephrine exposure and acute kidney injury (AKI) and intensive care unit (I...

    Authors: Pierre Huette, Mouhamed Djahoum Moussa, Christophe Beyls, Pierre-Grégoire Guinot, Mathieu Guilbart, Patricia Besserve, Mehdi Bouhlal, Sarah Mounjid, Hervé Dupont, Yazine Mahjoub, Audrey Michaud and Osama Abou-Arab
    Citation: Annals of Intensive Care 2022 12:61
  48. Authors: Benoit Painvin, Stephan Ehrmann, Arnaud W. Thille and Jean-Marc Tadié
    Citation: Annals of Intensive Care 2022 12:60

    The original article was published in Annals of Intensive Care 2022 12:31

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2022 12:63

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2022 12:63

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