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  1. In this review, we aimed to comprehensively summarize current literature on pathophysiology, relevance, diagnosis and treatment of fluid accumulation in patients with sepsis/septic shock. Fluid accumulation sy...

    Authors: Carmen Andrea Pfortmueller, Wojciech Dabrowski, Rob Wise, Niels van Regenmortel and Manu L. N. G. Malbrain
    Citation: Annals of Intensive Care 2024 14:115
  2. Severe acute respiratory infections, such as community-acquired pneumonia, hospital-acquired pneumonia, and ventilator-associated pneumonia, constitute frequent and lethal pulmonary infections in the intensive...

    Authors: Pedro Póvoa, Luís Coelho, José Pedro Cidade, Adrian Ceccato, Andrew Conway Morris, Jorge Salluh, Vandack Nobre, Saad Nseir, Ignacio Martin-Loeches, Thiago Lisboa, Paula Ramirez, Anahita Rouzé, Daniel A. Sweeney and Andre C. Kalil
    Citation: Annals of Intensive Care 2024 14:113
  3. In sepsis, initial resuscitation with fluids is followed by efforts to achieve a negative fluid balance. However, patients with sepsis-associated acute kidney injury (SA-AKI) often need diuretic or renal repla...

    Authors: Lars Palmowski, Simone Lindau, Laura Contreras Henk, Britta Marko, Andrea Witowski, Hartmuth Nowak, Sandra E. Stoll, Kai Zacharowski, Bernd W. Böttiger, Jürgen Peters, Michael Adamzik, Fabian Dusse and Tim Rahmel
    Citation: Annals of Intensive Care 2024 14:111
  4. Although the present diagnosis of acute kidney injury (AKI) involves measurement of acute increases in serum creatinine (SC) and reduced urine output (UO), measurement of UO is underutilized for diagnosis of A...

    Authors: Manu L. N. G. Malbrain, Krista Tantakoun, Anthony T. Zara, Nicole C. Ferko, Timothy Kelly and Wojciech Dabrowski
    Citation: Annals of Intensive Care 2024 14:110
  5. Post-intensive care syndrome (PICS), defined as physical, cognitive, and mental-health symptoms persisting long after intensive-care-unit (ICU) discharge, is increasingly recognised as a healthcare priority. D...

    Authors: Maïté Agbakou, Margot Combet, Maëlle Martin, Gauthier Blonz, Luc Desmedt, Amélie Seguin, Jérémie Lemarié, Olivier Zambon, Jean Reignier, Jean-Baptiste Lascarrou, Stephan Ehrmann and Emmanuel Canet
    Citation: Annals of Intensive Care 2024 14:109
  6. Dynamic arterial elastance (Eadyn) has been investigated for its ability to predict hypotension during the weaning of vasopressors. Our study focused on assessing Eadyn’s performance in the context of critically ...

    Authors: Jorge Iván Alvarado-Sánchez, Sergio Salazar-Ruiz, Juan Daniel Caicedo-Ruiz, Juan José Diaztagle-Fernández, Yenny Rocio Cárdenas-Bolivar, Fredy Leonardo Carreño-Hernandez, Andrés Felipe Mora-Salamanca, Andrea Valentina Montañez-Nariño, María Valentina Stozitzky-Ríos, Carlos Santacruz-Herrera, Gustavo Adolfo Ospina-Tascón and Michael R. Pinsky
    Citation: Annals of Intensive Care 2024 14:108
  7. Adults in the intensive care unit (ICU) commonly experience distressing symptoms and other concerns such as pain, delirium, and breathlessness. Breathlessness management is not supported by any ICU guidelines,...

    Authors: Ben R. Richardson, Maxens Decavèle, Alexandre Demoule, Fliss E. M. Murtagh and Miriam J. Johnson
    Citation: Annals of Intensive Care 2024 14:107
  8. The recruitment-to-inflation ratio (R/I) has been recently proposed to bedside assess response to PEEP. The impact of PEEP on ventilator-induced lung injury depends on the extent of dynamic strain reduction. W...

    Authors: Francesco Murgolo, Domenico L. Grieco, Savino Spadaro, Nicola Bartolomeo, Rossella di Mussi, Luigi Pisani, Marco Fiorentino, Alberto Maria Crovace, Luca Lacitignola, Francesco Staffieri and Salvatore Grasso
    Citation: Annals of Intensive Care 2024 14:106
  9. Patients on veno-arterial extracorporeal membrane oxygenation (V-A ECMO) support are at a high risk of hemorrhagic complications, including upper gastrointestinal bleeding (UGIB). The objective of this study w...

    Authors: Quentin de Roux, Yekcan Disli, Wulfran Bougouin, Marie Renaudier, Ali Jendoubi, Jean-Claude Merle, Mathilde Delage, Lucile Picard, Faiza Sayagh, Chamsedine Cherait, Thierry Folliguet, Christophe Quesnel, Aymeric Becq and Nicolas Mongardon
    Citation: Annals of Intensive Care 2024 14:104
  10. Patients with advanced critical illness often receive more intensive treatment than they would choose for themselves, which contributes to high health care costs near the end of life. The purpose of this study...

    Authors: Sarah K. Andersen, Chung-Chou H. Chang, Robert M. Arnold, Caroline Pidro, Joseph M. Darby, Derek C. Angus and Douglas B. White
    Citation: Annals of Intensive Care 2024 14:103
  11. A notable increase in severe cases of COVID-19, with significant hospitalizations due to the emergence and spread of JN.1 was observed worldwide in late 2023 and early 2024. However, no clinical data are avail...

    Authors: Nicolas de Prost, Etienne Audureau, Antoine Guillon, Lynda Handala, Sébastien Préau, Aurélie Guigon, Fabrice Uhel, Quentin Le Hingrat, Flora Delamaire, Claire Grolhier, Fabienne Tamion, Alice Moisan, Cédric Darreau, Jean Thomin, Damien Contou, Amandine Henry…
    Citation: Annals of Intensive Care 2024 14:101
  12. Previous retrospective research has shown that maintaining prone positioning (PP) for an average of 40 h is associated with an increase of survival rates in intubated patients with COVID-19-related acute respi...

    Authors: Christophe Le Terrier, Thaïs Walter, Said Lebbah, David Hajage, Florian Sigaud, Claude Guérin, Luc Desmedt, Steve Primmaz, Vincent Jousselin, Chiara Della Badia, Jean-Damien Ricard, Jérôme Pugin and Nicolas Terzi
    Citation: Annals of Intensive Care 2024 14:100
  13. EEG reactivity is a predictor for neurological outcome in comatose patients after cardiac arrest (CA); however, its application is limited by variability in stimulus types and visual assessment. We aimed to ev...

    Authors: Gang Liu, Yuan Wang, Fei Tian, Weibi Chen, Lili Cui, Mengdi Jiang, Yan Zhang, Keming Gao, Yingying Su and Hongxing Wang
    Citation: Annals of Intensive Care 2024 14:99
  14. Current guidelines recommend using antifungals for selected patients with health care-associated intra-abdominal infection (HC-IAI), but this recommendation is based on a weak evidence. This study aimed to ass...

    Authors: Djamel Mokart, Mehdi Boutaba, Luca Servan, Benjamin Bertrand, Olivier Baldesi, Laurent Lefebvre, Frédéric Gonzalez, Magali Bisbal, Bruno Pastene, Gary Duclos, Marion Faucher, Laurent Zieleskiewicz, Laurent Chow-Chine, Antoine Sannini, Jean Marie Boher, Romain Ronflé…
    Citation: Annals of Intensive Care 2024 14:98
  15. Prognosis determines major decisions regarding treatment for critically ill patients. Statistical models have been developed to predict the probability of survival and other outcomes of intensive care. Althoug...

    Authors: Michael Beil, Rui Moreno, Jakub Fronczek, Yuri Kogan, Rui Paulo Jorge Moreno, Hans Flaatten, Bertrand Guidet, Dylan de Lange, Susannah Leaver, Akiva Nachshon, Peter Vernon van Heerden, Leo Joskowicz, Sigal Sviri, Christian Jung and Wojciech Szczeklik
    Citation: Annals of Intensive Care 2024 14:97
  16. Rhabdomyolysis is a serious condition that can lead to acute kidney injury with the need of renal replacement therapy (RRT). The cytokine adsorber Cytosorb® (CS) can be used for extracorporeal myoglobin elimin...

    Authors: Helen Graf, Caroline Gräfe, Mathias Bruegel, Michael Zoller, Nils Maciuga, Sandra Frank, Lorenz Weidhase, Michael Paal and Christina Scharf
    Citation: Annals of Intensive Care 2024 14:96
  17. Evidence for the management of pregnant women with acute hypoxaemic respiratory failure (AHRF) is currently lacking. The likelihood of avoiding intubation and the risks of continuing the pregnancy under invasi...

    Authors: Frédérique Schortgen, Cecilia Tabra Osorio, Suela Demiri, Cléo Dzogang, Camille Jung, Audrey Lavenu and Edouard Lecarpentier
    Citation: Annals of Intensive Care 2024 14:94
  18. The COVID-19 pandemic has highlighted the importance of intensive care units (ICUs) and their organization in healthcare systems. However, ICU capacity and availability are ongoing concerns beyond the pandemic...

    Authors: Sacha Sarfati, Stephan Ehrmann, Dominique Vodovar, Boris Jung, Nadia Aissaoui, Cédric Darreau, Wulfran Bougouin, Nicolas Deye, Hatem Kallel, Khaldoun Kuteifan, Charles-Edouard Luyt, Nicolas Terzi, Thierry Vanderlinden, Christophe Vinsonneau, Grégoire Muller and Christophe Guitton
    Citation: Annals of Intensive Care 2024 14:92
  19. The objective was to compare sevoflurane, a volatile sedation agent with potential bronchodilatory properties, with propofol on respiratory mechanics in critically ill patients with COPD exacerbation.

    Authors: Boris Jung, Maxime Fosset, Matthieu Amalric, Elias Baedorf-Kassis, Brian O’Gara, Todd Sarge, Valerie Moulaire, Vincent Brunot, Arnaud Bourdin, Nicolas Molinari and Stefan Matecki
    Citation: Annals of Intensive Care 2024 14:91
  20. Authors: Beatrice Beck-Schimmer, Erik Schadde, Urs Pietsch, Miodrag Filipovic, Seraina Dübendorfer-Dalbert, Patricia Fodor, Tobias Hübner, Reto Schuepbach, Peter Steiger, Sascha David, Bernard D. Krüger, Thomas A. Neff and Martin Schläpfer
    Citation: Annals of Intensive Care 2024 14:90

    The original article was published in Annals of Intensive Care 2024 14:41

  21. Recent years have seen a resurgence of interest for the renin–angiotensin–aldosterone system in critically ill patients. Emerging data suggest that this vital homeostatic system, which plays a crucial role in ...

    Authors: Adrien Picod, Bruno Garcia, Dirk Van Lier, Peter Pickkers, Antoine Herpain, Alexandre Mebazaa and Feriel Azibani
    Citation: Annals of Intensive Care 2024 14:89
  22. Authors: Pierre Bay, Etienne Audureau, Sébastien Préau, Raphaël Favory, Aurélie Guigon, Nicholas Heming, Elyanne Gault, Tài Pham, Amal Chaghouri, Matthieu Turpin, Laurence Morand-Joubert, Sébastien Jochmans, Aurélia Pitsch, Sylvie Meireles, Damien Contou, Amandine Henry…
    Citation: Annals of Intensive Care 2024 14:87

    The original article was published in Annals of Intensive Care 2024 14:65

  23. Protective ventilation seems crucial during early Acute Respiratory Distress Syndrome (ARDS), but the optimal duration of lung protection remains undefined. High driving pressures (ΔP) and excessive patient ve...

    Authors: Eduardo L. V. Costa, Glasiele C. Alcala, Mauro R. Tucci, Ewan Goligher, Caio C. Morais, Jose Dianti, Miyuki A. P. Nakamura, Larissa B. Oliveira, Sérgio M. Pereira, Carlos Toufen Jr, Carmen S. V. Barbas, Carlos R. R. Carvalho and Marcelo B. P. Amato
    Citation: Annals of Intensive Care 2024 14:85
  24. The clinical value of the trajectory of temporal changes in acute kidney injury (AKI) biomarkers has not been well established among intensive care unit (ICU) patients.

    Authors: Ryohei Horie, Naoki Hayase, Toshifumi Asada, Miyuki Yamamoto, Takehiro Matsubara and Kent Doi
    Citation: Annals of Intensive Care 2024 14:84
  25. Immunosuppression at intensive care unit (ICU) admission has been associated with a higher incidence of ICU-acquired infections, some of them related to opportunistic pathogens. However, the association of imm...

    Authors: Ghadi Zebian, Louis Kreitmann, Marion Houard, Antoine Piantoni, Gaetan Piga, Sarah Ruffier des Aimes, Bérénice Holik, Frédéric Wallet, Julien Labreuche and Saad Nseir
    Citation: Annals of Intensive Care 2024 14:83
  26. Authors: Charles-Hervé Vacheron, Anne Kaas, Jean-Philippe Rasigade, Frederic Aubrun, Laurent Argaud, Baptiste Balanca, Jean-Luc Fellahi, Jean Christophe Richard, Anne-Claire Lukaszewicz, Florent Wallet, Olivier Dauwalder and Arnaud Friggeri
    Citation: Annals of Intensive Care 2024 14:81

    The original article was published in Annals of Intensive Care 2024 14:73

  27. The renin-angiotensin system (RAS) constitutes one of the principal mechanisms to maintain hemodynamic and fluid homeostasis. However, most research until now on RAS primarily focuses on its relationship with ...

    Authors: Yuki Kotani, Mark Chappell, Giovanni Landoni, Alexander Zarbock, Rinaldo Bellomo and Ashish K. Khanna
    Citation: Annals of Intensive Care 2024 14:79
  28. Reverse triggering (RT) was described in 2013 as a form of patient-ventilator asynchrony, where patient’s respiratory effort follows mechanical insufflation. Diagnosis requires esophageal pressure (Pes) or diaphr...

    Authors: Robert Jackson, Audery Kim, Nikolay Moroz, L. Felipe Damiani, Domenico Luca Grieco, Thomas Piraino, Jan O. Friedrich, Alain Mercat, Irene Telias and Laurent J. Brochard
    Citation: Annals of Intensive Care 2024 14:78
  29. To identify key components and variations in family-centered care practices.

    Authors: Élie Azoulay, Nancy Kentish-Barnes, Carole Boulanger, Giovanni Mistraletti, Margo van Mol, Gabriel Heras-La Calle, Elisa Estenssoro, Peter Vernon van Heerden, Maria-Cruz Martin Delgado, Anders Perner, Yaseen M Arabi, Sheila Nainan Myatra, Jon Henrik Laake, Jan J. De Waele, Michael Darmon and Maurizio Cecconi
    Citation: Annals of Intensive Care 2024 14:77
  30. A 10-day dexamethasone regimen has emerged as the internationally adopted standard-of-care for severe COVID-19 patients. However, the immune response triggered by SARS-CoV-2 infection remains a complex and dyn...

    Authors: Guillaume Monneret, Nicolas Voirin, Jean-Christophe Richard, Martin Cour, Thomas Rimmelé, Lorna Garnier, Hodane Yonis, Remy Coudereau, Morgane Gossez, Christophe Malcus, Florent Wallet, Marie-Charlotte Delignette, Frederic Dailler, Marielle Buisson, Laurent Argaud, Anne-Claire Lukaszewicz…
    Citation: Annals of Intensive Care 2024 14:76
  31. Current data on post-discharge mortality and rehospitalization is still insufficient among in-hospital survivors of cardiogenic shock (CS), including acute myocardial infarction (AMI) and non-AMI survivors.

    Authors: Shih-Chieh Chien, Cheng-An Wang, Hung-Yi Liu, Chao-Feng Lin, Chun-Yao Huang and Li-Nien Chien
    Citation: Annals of Intensive Care 2024 14:74
  32. The efficacy and safety of cefiderocol in ICU patients with difficult-to-treat resistance (DTR) non-fermenting Gram-negative bacteria (Nf-GNB) are not as well-established. Consequently, we conducted a cohort s...

    Authors: Charles-Hervé Vacheron, Anne Kaas, Jean-Philippe Rasigade, Frederic Aubrun, Laurent Argaud, Baptiste Balanca, Jean-Luc Fellahi, Jean Christophe Richard, Anne-Claire Lukaszewicz, Florent Wallet, Olivier Dauwalder and Arnaud Friggeri
    Citation: Annals of Intensive Care 2024 14:73

    The Correction to this article has been published in Annals of Intensive Care 2024 14:81

  33. COVID-19-associated pulmonary fibrosis remains frequent. This study aimed to investigate pulmonary redox balance in COVID-19 ARDS patients and possible relationship with pulmonary fibrosis and long-term lung a...

    Authors: Chun Yang, Yuanyuan Tan, Zihao Li, Lei Hu, Yuanyuan Chen, Shouliang Zhu, Jiawei Hu, Tingting Huai, Mingqing Li, Guobin Zhang, Dewang Rao, Guanghe Fei, Min Shao and Zhenxing Ding
    Citation: Annals of Intensive Care 2024 14:72
  34. Very old critically ill patients pose a growing challenge for intensive care. Critical illness and the burden of treatment in the intensive care unit (ICU) can lead to a long-lasting decline of functional and ...

    Authors: Jeremy M. Jacobs, Ana Rahamim, Michael Beil, Bertrand Guidet, Helene Vallet, Hans Flaatten, Susannah K. Leaver, Dylan de Lange, Wojciech Szczeklik, Christian Jung and Sigal Sviri
    Citation: Annals of Intensive Care 2024 14:71
  35. Hospital-acquired bloodstream infections are common in the intensive care unit (ICU) and have a high mortality rate. Patients with cirrhosis are especially susceptible to infections, yet there is a knowledge g...

    Authors: Hannah Wozniak, Alexis Tabah, François Barbier, Stéphane Ruckly, Ambre Loiodice, Murat Akova, Marc Leone, Andrew Conway Morris, Matteo Bassetti, Kostoula Arvaniti, Ricard Ferrer, Liesbet de Bus, Jose Artur Paiva, Hendrik Bracht, Adam Mikstacki, Adel Alsisi…
    Citation: Annals of Intensive Care 2024 14:70
  36. Alongside the recent worldwide expansion of hypervirulent Klebsiella pneumoniae (KP) infections, the available literature regarding cases of community acquired pneumonias (KP-CAP) remains scarce but reports a str...

    Authors: Vincent Grosjean, Simon B. Gressens, Tài Pham, Stéphane Gaudry, Hafid Ait-Oufella, Nicolas De Prost, Julien Mayaux, Emmanuel Guerot, Véronique Leflon-Guibout, Noémie Mayer, Frédéric Bert, Nathalie Gault, Clément R. Massonnaud and Damien Roux
    Citation: Annals of Intensive Care 2024 14:69
  37. It remains unclear whether conservative oxygen therapy (COT) or liberal oxygen therapy (LOT) is more beneficial to the clinical outcomes of intensive care unit (ICU) patients. We systematically reviewed the ef...

    Authors: Xin-yu Li, Bing Dai, Hai-jia Hou, Hong-wen Zhao, Wei Wang, Jian Kang and Wei Tan
    Citation: Annals of Intensive Care 2024 14:68
  38. To describe ventilator-associated pneumonia (VAP) recurrence in COVID-19 patients requiring extracorporeal membrane oxygenation (ECMO) support, and to evaluate the impact of antimicrobial treatment duration of...

    Authors: Elena Collado-Lledó, Quentin Moyon, Juliette Chommeloux, Marc Pineton de Chambrun, Guillaume Hékimian, Ouriel Saura, David Lévy, Matthieu Schmidt, Alain Combes, Charles-Edouard Luyt and Lucie Le Fevre
    Citation: Annals of Intensive Care 2024 14:67
  39. Multiple randomized controlled studies have compared numerous antibiotic regimens, including new, recently commercialized antibiotics in the treatment of nosocomial pneumonia (NP). The objective of this Bayesi...

    Authors: David Luque Paz, Dara Chean, Pierre Tattevin, Damien Luque Paz, Betsega Assefa Bayeh, Achille Kouatchet, Delphine Douillet and Jérémie Riou
    Citation: Annals of Intensive Care 2024 14:66

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