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  1. Hemadsorption of cytokines is used in critically ill patients with sepsis or septic shock. Concerns have been raised that the cytokine adsorber CytoSorb® unintentionally adsorbs vancomycin. This study aimed to qu...

    Authors: Christina Scharf, Ferdinand Weinelt, Ines Schroeder, Michael Paal, Michael Weigand, Michael Zoller, Michael Irlbeck, Charlotte Kloft, Josef Briegel and Uwe Liebchen
    Citation: Annals of Intensive Care 2022 12:44
  2. Hospital-acquired pneumonia (HAP) is the most common and severe complication in patients treated with venoarterial extracorporeal membrane oxygenation (VA ECMO) and its diagnosis remains challenging. Nothing i...

    Authors: Jean Pasqueron, Pauline Dureau, Gauthier Arcile, Baptiste Duceau, Geoffroy Hariri, Victoria Lepère, Guillaume Lebreton, Jean-Jacques Rouby and Adrien Bouglé
    Citation: Annals of Intensive Care 2022 12:43
  3. The impact of underlying comorbidities on the clinical presentation, management and outcomes in patients with ARDS is poorly understood and deserves further investigation.

    Authors: Emanuele Rezoagli, Bairbre A. McNicholas, Fabiana Madotto, Tài Pham, Giacomo Bellani and John G. Laffey
    Citation: Annals of Intensive Care 2022 12:42
  4. High-intensity noninvasive positive pressure ventilation (NPPV) is a novel ventilatory approach to maximally decreasing elevated arterial carbon dioxide tension (PaCO2) toward normocapnia with stepwise up-titrati...

    Authors: Zujin Luo, Zhixin Cao, Yichong Li, Jiawei Jin, Wei Sun, Jian Zhu, Na Zhao, Jichen Liu, Bing Wei, Yue Hu, Ying Zhang, Yingmin Ma and Chen Wang
    Citation: Annals of Intensive Care 2022 12:41
  5. Hyperoxia is associated with increased morbidity and mortality in the intensive care unit. Classical noninvasive measurements of oxygen saturation with pulse oximeters are unable to detect hyperoxia. The Oxyge...

    Authors: Hugues de Courson, Thomas Julien-Laferrière, Delphine Georges, Philippe Boyer, Eric Verchère and Matthieu Biais
    Citation: Annals of Intensive Care 2022 12:40
  6. The reports of an early and profound acquired immunodepression syndrome (AIDs) in ICU patients had gained sufficient credence to modify the paradigm of acute inflammation. However, despite several articles pub...

    Authors: C. de Roquetaillade, C. Dupuis, V. Faivre, A. C. Lukaszewicz, C. Brumpt and D. Payen
    Citation: Annals of Intensive Care 2022 12:39
  7. Central venous catheter (CVC) insertion complications are a prevalent and important problem in the intensive care unit (ICU), and source control by immediate catheter removal is considered urgent in patients w...

    Authors: Yiyue Zhong, Liehua Deng, Limin Zhou, Shaoling Liao, Liqun Yue, Shi Wu Wen, Rihua Xie, Yuezhen Lu, Liangqing Zhang, Jing Tang and Jiayuan Wu
    Citation: Annals of Intensive Care 2022 12:38
  8. The COVID-19 pandemic tested the capacity of intensive care units (ICU) to respond to a crisis and demonstrated their fragility. Unsurprisingly, higher than usual mortality rates, lengths of stay (LOS), and IC...

    Authors: Jorge I. F. Salluh, Pedro Kurtz, Leonardo S. L. Bastos, Amanda Quintairos, Fernando G. Zampieri and Fernando A. Bozza
    Citation: Annals of Intensive Care 2022 12:37
  9. Patients presenting with acute hypercapnic respiratory failure due to exacerbations of chronic obstructive pulmonary disease (AECOPD) are typically managed with non-invasive ventilation (NIV). The impact of lo...

    Authors: Nicholas A. Barrett, Nicholas Hart, Kathleen J. R. Daly, Martina Marotti, Eirini Kostakou, Chris Carlin, Stephanie Lua, Suveer Singh, Andrew Bentley, Abdel Douiri and Luigi Camporota
    Citation: Annals of Intensive Care 2022 12:36
  10. External chest-wall compression (ECC) is sometimes used in ARDS patients despite lack of evidence. It is currently unknown whether this practice has any clinical benefit in patients with COVID-19 ARDS (C-ARDS)...

    Authors: Luca Bastia, Emanuele Rezoagli, Marcello Guarnieri, Doreen Engelberts, Clarissa Forlini, Francesco Marrazzo, Stefano Spina, Gabriele Bassi, Riccardo Giudici, Martin Post, Giacomo Bellani, Roberto Fumagalli, Laurent J. Brochard and Thomas Langer
    Citation: Annals of Intensive Care 2022 12:35
  11. Whether sepsis-associated diaphragm dysfunction may improve despite the exposure of mechanical ventilation in critically ill patients is unclear. This study aims at describing the diaphragm function time cours...

    Authors: Marie Lecronier, Boris Jung, Nicolas Molinari, Jérôme Pinot, Thomas Similowski, Samir Jaber, Alexandre Demoule and Martin Dres
    Citation: Annals of Intensive Care 2022 12:34
  12. Phlebitis is an important complication occurring in patients with peripheral intravascular catheters (PIVCs). The risk factors for phlebitis in the intensive care unit (ICU) was examined.

    Authors: Hideto Yasuda, Claire M. Rickard, Nicole Marsh, Ryohei Yamamoto, Yuki Kotani, Yuki Kishihara, Natsuki Kondo, Kosuke Sekine, Nobuaki Shime, Keita Morikane and Takayuki Abe
    Citation: Annals of Intensive Care 2022 12:33
  13. Varicella-zoster virus (VZV) is one of the main viruses responsible of acute encephalitis. However, data on the prognosis and neurologic outcome of critically ill patients with VZV encephalitis are limited. We...

    Authors: Adrien Mirouse, Romain Sonneville, Keyvan Razazi, Sybille Merceron, Laurent Argaud, Naïke Bigé, Stanislas Faguer, Pierre Perez, Guillaume Géri, Claude Guérin, Anne-Sophie Moreau, Laurent Papazian, René Robert, François Barbier, Frédérique Ganster, Julien Mayaux…
    Citation: Annals of Intensive Care 2022 12:32
  14. Transfers from one intensive care unit (ICU) to another ICU are associated with increased length of intensive care and hospital stay. Inter-hospital ICU transfers are carried out for three main reasons: clinic...

    Authors: Fredric Parenmark and Sten M. Walther
    Citation: Annals of Intensive Care 2022 12:31
  15. Authors: Frank Bidar, Sarah Hamada, Morgane Gossez, Remy Coudereau, Jonathan Lopez, Marie-Angelique Cazalis, Claire Tardiveau, Karen Brengel-Pesce, Marine Mommert, Marielle Buisson, Filippo Conti, Thomas Rimmelé, Anne-Claire Lukaszewicz, Laurent Argaud, Martin Cour, Guillaume Monneret…
    Citation: Annals of Intensive Care 2022 12:30

    The original article was published in Annals of Intensive Care 2022 12:21

  16. Regional citrate anticoagulation (RCA) is recommended for continuous renal replacement therapy (CRRT). However, filter life varies and premature filter clotting can occur. The aims of this explorative prospect...

    Authors: Richard Fisher, Gary W. Moore, Michael J. Mitchell, Letian Dai, Siobhan Crichton, Nuttha Lumlertgul and Marlies Ostermann
    Citation: Annals of Intensive Care 2022 12:29
  17. Authors: Jakob Wollborn and Ulrich Goebel
    Citation: Annals of Intensive Care 2022 12:28

    The original article was published in Annals of Intensive Care 2022 12:27

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2022 12:27

    The Research to this article has been published in Annals of Intensive Care 2021 11:175

  18. Authors: Thibaut Belveyre, Can Ince and Philippe Guerci
    Citation: Annals of Intensive Care 2022 12:27

    The original article was published in Annals of Intensive Care 2021 11:175

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2022 12:28

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2022 12:28

  19. Critically ill old intensive care unit (ICU) patients suffering from Sars-CoV-2 disease (COVID-19) are at increased risk for adverse outcomes. This post hoc analysis investigates the association of the Activit...

    Authors: Raphael Romano Bruno, Bernhard Wernly, Hans Flaatten, Jesper Fjølner, Antonio Artigas, Philipp Heinrich Baldia, Stephan Binneboessel, Bernardo Bollen Pinto, Joerg C. Schefold, Georg Wolff, Malte Kelm, Michael Beil, Sigal Sviri, Peter Vernon van Heerden, Wojciech Szczeklik, Muhammed Elhadi…
    Citation: Annals of Intensive Care 2022 12:26
  20. To assess in comatose patients after cardiac arrest (CA) if amplitudes of two somatosensory evoked potentials (SSEP) responses, namely, N20-baseline (N20-b) and N20–P25, are predictive of neurological outcome.

    Authors: Sarah Benghanem, Lee S. Nguyen, Martine Gavaret, Jean-Paul Mira, Frédéric Pène, Julien Charpentier, Angela Marchi and Alain Cariou
    Citation: Annals of Intensive Care 2022 12:25
  21. The clinical impact and outcomes of ventilator-associated pneumonia (VAP) have been scarcely investigated in patients with the acute respiratory distress syndrome (ARDS).

    Authors: Marc Le Pape, Céline Besnard, Camelia Acatrinei, Jérôme Guinard, Maxime Boutrot, Claire Genève, Thierry Boulain and François Barbier
    Citation: Annals of Intensive Care 2022 12:24
  22. Survivors of viral ARDS are at risk of long-term physical, functional and neuropsychological complications resulting from the lung injury itself, but also from potential multiorgan dysfunction, and the long st...

    Authors: Guillaume Eberst, Fréderic Claudé, Lucie Laurent, Aurelia Meurisse, Pauline Roux-Claudé, Cindy Barnig, Dewi Vernerey, Sophie Paget-Bailly, Kevin Bouiller, Catherine Chirouze, Julien Behr, Franck Grillet, Ophélie Ritter, Sinan Karaer, Sébastien Pili-Floury, Hadrien Winiszewski…
    Citation: Annals of Intensive Care 2022 12:23
  23. Respiratory pendelluft phenomenon, defined as intrapulmonary gas redistribution caused by asynchronous alveolar ventilation, could be potentially harmful by inducing lung injury. The aim of the present study w...

    Authors: Yi Chi, Zhanqi Zhao, Inéz Frerichs, Yun Long and Huaiwu He
    Citation: Annals of Intensive Care 2022 12:22
  24. Lymphopenia is a hallmark of severe coronavirus disease 19 (COVID-19). Similar alterations have been described in bacterial sepsis and therapeutic strategies targeting T cell function such as recombinant human...

    Authors: Frank Bidar, Sarah Hamada, Morgane Gossez, Remy Coudereau, Jonathan Lopez, Marie-Angelique Cazalis, Claire Tardiveau, Karen Brengel-Pesce, Marine Mommert, Marielle Buisson, Filippo Conti, Thomas Rimmelé, Anne-Claire Lukaszewicz, Laurent Argaud, Martin Cour, Guillaume Monneret…
    Citation: Annals of Intensive Care 2022 12:21

    The Correction to this article has been published in Annals of Intensive Care 2022 12:30

  25. Intensive care unit (ICU) admissions among older adults are expected to increase, while the benefit remains uncertain. The availability of ICU beds varies between hospitals and between countries and is an impo...

    Authors: Ran Abuhasira, Matthew Anstey, Victor Novack, Somnath Bose, Daniel Talmor and Lior Fuchs
    Citation: Annals of Intensive Care 2022 12:20
  26. Authors: Marco Ferrari, Valentina Quaresima and Felix Scholkmann
    Citation: Annals of Intensive Care 2022 12:19

    The original article was published in Annals of Intensive Care 2022 12:2

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2022 12:18

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2022 12:18

  27. The concept of frailty provides an age-independent, easy-to-use tool for risk stratification. We aimed to summarize the evidence on the efficacy of frailty tools in risk assessment in COVID-19 patients.

    Authors: Máté Rottler, Klementina Ocskay, Zoltán Sipos, Anikó Görbe, Marcell Virág, Péter Hegyi, Tihamér Molnár, Bálint Erőss, Tamás Leiner and Zsolt Molnár
    Citation: Annals of Intensive Care 2022 12:17
  28. To describe health-related quality of life (HRQoL) and dyspnea of COVID-19, 2 and 12 months after an intensive care unit (ICU) stay.

    Authors: Alexandre Demoule, Elise Morawiec, Maxens Decavele, Raphaelle Ohayon, Roxane Malrin, Maria Alejandra Galarza-Jimenez, Pierantonio Laveneziana, Capucine Morelot-Panzini, Thomas Similowski, Yann De Rycke and Jesus Gonzalez-Bermejo
    Citation: Annals of Intensive Care 2022 12:16
  29. Tumor lysis syndrome (TLS) is a life-threatening complication during the treatment of malignant neoplasia. We sought to describe characteristics and predictors of acute kidney injury (AKI), remission and morta...

    Authors: Moustafa Abdel-Nabey, Anis Chaba, Justine Serre, Etienne Lengliné, Elie Azoulay, Michael Darmon and Lara Zafrani
    Citation: Annals of Intensive Care 2022 12:15
  30. Acute kidney injury (AKI) is a common disease in the intensive care unit (ICU). AKI patients with nonrecovery of renal function have a markedly increased risk of death compared with patients with recovery. The...

    Authors: Hui-Miao Jia, Li Cheng, Yi-Bing Weng, Jing-Yi Wang, Xi Zheng, Yi-Jia Jiang, Xin Xin, Shu-Yan Guo, Chao-Dong Chen, Fang-Xing Guo, Yu-Zhen Han, Tian-En Zhang and Wen-Xiong Li
    Citation: Annals of Intensive Care 2022 12:14
  31. A sequential change in body position from supine-to-both lateral positions under constant ventilatory settings could be used as a postural recruitment maneuver in case of acute respiratory distress syndrome (A...

    Authors: Rollin Roldán, Shalim Rodriguez, Fernando Barriga, Mauro Tucci, Marcus Victor, Glasiele Alcala, Renán Villamonte, Fernando Suárez-Sipmann, Marcelo Amato, Laurent Brochard and Gerardo Tusman
    Citation: Annals of Intensive Care 2022 12:13
  32. Acute kidney injury (AKI) is a frequent complication in cardiac arrest survivors and associated with adverse outcome. It remains unclear whether the incidence of AKI increases after the post-cardiac arrest con...

    Authors: Gladys N. Janssens, Joost Daemen, Jorrit S. Lemkes, Eva M. Spoormans, Dieuwertje Janssen, Corstiaan A. den Uil, Lucia S. D. Jewbali, Ton A. C. M. Heestermans, Victor A. W. M. Umans, Frank R. Halfwerk, Albertus Beishuizen, Joris Nas, Judith Bonnes, Peter M. van de Ven, Albert C. van Rossum, Paul W. G. Elbers…
    Citation: Annals of Intensive Care 2022 12:12
  33. To evaluate the association between ventilator type and hospital mortality in patients with acute respiratory distress syndrome (ARDS) related to COVID-19 (SARS-CoV2 infection), a single-center prospective obs...

    Authors: Alexis Ferré, Fabien Marquion, Marc Delord, Antoine Gros, Guillaume Lacave, Virginie Laurent, Sybille Merceron, Marine Paul, Christelle Simon, Gilles Troché, Clément Charbonnel, Stéphanie Marque-Juillet, Fabrice Bruneel and Stéphane Legriel
    Citation: Annals of Intensive Care 2022 12:10
  34. Since the publication of the 2018 Clinical Guidelines about sedation, analgesia, delirium, mobilization, and sleep deprivation in critically ill patients, no evaluation and adequacy assessment of these recomme...

    Authors: Mariana Luz, Bruna Brandão Barreto, Roberta Esteves Vieira de Castro, Jorge Salluh, Felipe Dal-Pizzol, Caio Araujo, Audrey De Jong, Gérald Chanques, Sheila Nainan Myatra, Eduardo Tobar, Carolina Gimenez-Esparza Vich, Federico Carini, Eugene Wesley Ely, Joanna L. Stollings, Kelly Drumright, John Kress…
    Citation: Annals of Intensive Care 2022 12:9
  35. The use of extracorporeal membrane oxygenation (ECMO) in pediatric patients with underlying malignancies remains controversial. However, in an era in which the survival rates for children with malignancies hav...

    Authors: Valerie Slooff, Rianne Hoogendoorn, Jeppe Sylvest Angaard Nielsen, John Pappachan, Angela Amigoni, Fabio Caramelli, Omer Aziz, Enno Wildschut, Sascha Verbruggen, Roman Crazzolara, Christian Dohna-Schwake, Jenny Potratz, Jef Willems, Judit Llevadias, Andrea Moscatelli, Alessia Montaguti…
    Citation: Annals of Intensive Care 2022 12:8
  36. Valproic acid (VPA) poisoning is responsible for life-threatening neurological and metabolic impairments. Despite only low-level evidence of effectiveness, L-carnitine has been used for years to prevent or rev...

    Authors: Philippe Nguyen, Lucie Chevillard, Ahmed S. Gouda, Hervé Gourlain, Laurence Labat, Isabelle Malissin, Nicolas Deye, Sebastian Voicu and Bruno Mégarbane
    Citation: Annals of Intensive Care 2022 12:7
  37. Duration of invasive mechanical ventilation (IMV) prior to extracorporeal membrane oxygenation (ECMO) affects outcome in acute respiratory distress syndrome (ARDS). In coronavirus disease 2019 (COVID-19) relat...

    Authors: Martina Hermann, Daniel Laxar, Christoph Krall, Christina Hafner, Oliver Herzog, Oliver Kimberger, Sebastian Koenig, Felix Kraft, Mathias Maleczek, Klaus Markstaller, Oliver Robak, Bernhard Rössler, Eva Schaden, Peter Schellongowski, Mathias Schneeweiss-Gleixner, Thomas Staudinger…
    Citation: Annals of Intensive Care 2022 12:6
  38. To assess trends in the quality of care for COVID-19 patients at the ICU over the course of time in the Netherlands.

    Authors: Dave A. Dongelmans, Fabian Termorshuizen, Sylvia Brinkman, Ferishta Bakhshi-Raiez, M. Sesmu Arbous, Dylan W. de Lange, Bas C. T. van Bussel and Nicolette F. de Keizer
    Citation: Annals of Intensive Care 2022 12:5
  39. Authors: Nicolas Massart, Virginie Maxime, Pierre Fillatre, Keyvan Razazi, Alexis Ferré, Pierre Moine, Francois Legay, Guillaume Voiriot, Marlene Amara, Francesca Santi, Saad Nseir, Stephanie Marque-Juillet, Rania Bounab, Nicolas Barbarot, Fabrice Bruneel and Charles-Edouard Luyt
    Citation: Annals of Intensive Care 2022 12:4

    The original article was published in Annals of Intensive Care 2021 11:183

  40. The composition of the gut microbiota is highly dynamic and changes according to various conditions. The gut microbiota mainly includes difficult-to-cultivate anaerobic bacteria, hence knowledge about its comp...

    Authors: Piotr Szychowiak, Khanh Villageois-Tran, Juliette Patrier, Jean-François Timsit and Étienne Ruppé
    Citation: Annals of Intensive Care 2022 12:3
  41. Ventilator-associated pneumonia (VAP) causes increased mortality, prolonged hospital stay and increased healthcare costs. Prevention of VAP in intensive care units (ICUs) is currently based on several measures...

    Authors: Pierre Damas, Caroline Legrain, Bernard Lambermont, Nadia Dardenne, Julien Guntz, Grâce Kisoka, Pierre Demaret, Anne-Françoise Rousseau, Laurent Jadot, Sonia Piret, Didier Noirot, Axelle Bertrand, Anne-Françoise Donneau and Benoît Misset
    Citation: Annals of Intensive Care 2022 12:1
  42. Authors: Sebastien Preau, Dominique Vodovar, Boris Jung, Steve Lancel, Lara Zafrani, Aurelien Flatres, Mehdi Oualha, Guillaume Voiriot, Youenn Jouan, Jeremie Joffre, Fabrice Uhel, Nicolas De Prost, Stein Silva, Eric Azabou and Peter Radermacher
    Citation: Annals of Intensive Care 2021 11:185

    The original article was published in Annals of Intensive Care 2021 11:104

  43. There is growing interest towards the use of helmet noninvasive ventilation (NIV) for the management of acute hypoxemic respiratory failure. Gas conditioning through heat and moisture exchangers (HME) or heate...

    Authors: Filippo Bongiovanni, Domenico Luca Grieco, Gian Marco Anzellotti, Luca Salvatore Menga, Teresa Michi, Melania Cesarano, Valeria Raggi, Cecilia De Bartolomeo, Benedetta Mura, Giovanna Mercurio, Sonia D’Arrigo, Giuseppe Bello, Riccardo Maviglia, Mariano Alberto Pennisi and Massimo Antonelli
    Citation: Annals of Intensive Care 2021 11:184
  44. Patients infected with the severe acute respiratory syndrome coronavirus 2 (SARS-COV 2) and requiring intensive care unit (ICU) have a high incidence of hospital-acquired infections; however, data regarding ho...

    Authors: Nicolas Massart, Virginie Maxime, Pierre Fillatre, Keyvan Razazi, Alexis Ferré, Pierre Moine, Francois Legay, Guillaume Voiriot, Marlene Amara, Francesca Santi, Saad Nseir, Stephanie Marque-Juillet, Rania Bounab, Nicolas Barbarot, Fabrice Bruneel and Charles-Edouard Luyt
    Citation: Annals of Intensive Care 2021 11:183

    The Correction to this article has been published in Annals of Intensive Care 2022 12:4

  45. Major therapeutic advances including immunotherapy and targeted therapies have been changing the face of oncology and resulted in improved prognosis as well as in new toxic complications. The aim of this study...

    Authors: Clara Vigneron, Julien Charpentier, Sandrine Valade, Jérôme Alexandre, Samy Chelabi, Lola-Jade Palmieri, Nathalie Franck, Valérie Laurence, Jean-Paul Mira, Matthieu Jamme and Frédéric Pène
    Citation: Annals of Intensive Care 2021 11:182
  46. Since 2019, European guidelines recommend considering extracorporeal life support as salvage strategy for the treatment of acute high-risk pulmonary embolism (PE) with circulatory collapse or cardiac arrest. H...

    Authors: Andrea Stadlbauer, Alois Philipp, Sebastian Blecha, Matthias Lubnow, Dirk Lunz, Jing Li, Armando Terrazas, Christof Schmid, Tobias J. Lange and Daniele Camboni
    Citation: Annals of Intensive Care 2021 11:181

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