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  1. Content type: Research

    Occlusion pressure at 100 ms (P0.1), defined as the negative pressure measured 100 ms after the initiation of an inspiratory effort performed against a closed respiratory circuit, has been shown to be well cor...

    Authors: François Beloncle, Lise Piquilloud, Pierre-Yves Olivier, Alice Vuillermoz, Elise Yvin, Alain Mercat and Jean-Christophe Richard

    Citation: Annals of Intensive Care 2019 9:104

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  2. Content type: Research

    Injury to endothelium and glycocalyx predisposes to vascular leak, which may subsequently lead to increased fluid requirements and worse outcomes. In this post hoc study of the prospective multicenter observat...

    Authors: Nina Inkinen, Ville Pettilä, Päivi Lakkisto, Anne Kuitunen, Sakari Jukarainen, Stepani Bendel, Outi Inkinen, Tero Ala-Kokko and Suvi T. Vaara

    Citation: Annals of Intensive Care 2019 9:103

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  3. Content type: Research

    High-flow nasal oxygen therapy (HFOT) is a promising first-line therapy for acute respiratory failure. However, its weaning has never been investigated and could lead to unnecessary prolonged intensive-care un...

    Authors: Maeva Rodriguez, Arnaud W. Thille, Florence Boissier, Anne Veinstein, Delphine Chatellier, René Robert, Sylvain Le Pape, Jean-Pierre Frat and Remi Coudroy

    Citation: Annals of Intensive Care 2019 9:101

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  4. Content type: Research

    Serum potassium concentrations are commonly between 3.5 and 5.0 mmol/l. Standardised protocols for potassium range and supplementation in the ICU are lacking. The purpose of this retrospective analysis of ICU ...

    Authors: Lilian Jo Engelhardt, Felix Balzer, Michael C. Müller, Julius J. Grunow, Claudia D. Spies, Kenneth B. Christopher, Steffen Weber-Carstens and Tobias Wollersheim

    Citation: Annals of Intensive Care 2019 9:100

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  5. Content type: Research

    In traumatic brain injury (TBI) patients desmopressin administration may induce rapid decreases in serum sodium and increase intracranial pressure (ICP).

    Authors: A. Harrois, J. R. Anstey, F. S. Taccone, A. A. Udy, G. Citerio, J. Duranteau, C. Ichai, R. Badenes, J. R. Prowle, A. Ercole, M. Oddo, A. Schneider, M. van der Jagt, S. Wolf, R. Helbok, D. W. Nelson…

    Citation: Annals of Intensive Care 2019 9:99

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  6. Content type: Research

    Despite the extensive use of high-flow nasal cannula (HFNC) therapy in intensive care units (ICU) for acute respiratory failure (ARF), its daily clinical practice has not been assessed. We designed a regional ...

    Authors: Emmanuel Besnier, Sinad Hobeika, Saad NSeir, Fabien Lambiotte, Damien Du Cheyron, Bertrand Sauneuf, Benoit Misset, Fabienne Tamion, Guillaume Schnell, Jack Richecoeur, Julien Maizel and Christophe Girault

    Citation: Annals of Intensive Care 2019 9:98

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  7. Content type: Research

    Heterogeneity of microvascular blood flow leading to tissue hypoxia is a common finding in patients with septic shock. It may be related to suboptimal systemic perfusion pressure and lead to organ failure. Map...

    Authors: Sigita Kazune, Anastasija Caica, Einars Luksevics, Karina Volceka and Andris Grabovskis

    Citation: Annals of Intensive Care 2019 9:97

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  8. Content type: Research

    There are limited epidemiological data on acute respiratory failure (ARF) in cardiogenic shock complicating acute myocardial infarction (AMI-CS). This study sought to evaluate the prevalence and outcomes of AR...

    Authors: Saraschandra Vallabhajosyula, Kianoush Kashani, Shannon M. Dunlay, Shashaank Vallabhajosyula, Saarwaani Vallabhajosyula, Pranathi R. Sundaragiri, Bernard J. Gersh, Allan S. Jaffe and Gregory W. Barsness

    Citation: Annals of Intensive Care 2019 9:96

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  9. Content type: Research

    Recent data suggest that hyperchloremia induced by fluid resuscitation is associated with acute kidney injury (AKI) and mortality, particularly in sepsis. Experimental studies showed that hyperchloremia could ...

    Authors: Morgane Commereuc, Camille Nevoret, Peter Radermacher, Sandrine Katsahian, Pierre Asfar and Frédérique Schortgen

    Citation: Annals of Intensive Care 2019 9:95

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  10. Content type: Research

    Aneurysmal subarachnoid hemorrhage (SAH) is an acute cerebrovascular disease associated with high mortality and long-term functional impairment among survivors. Systemic inflammatory responses after acute inju...

    Authors: Bruno Gonçalves, Pedro Kurtz, Ricardo Turon, Thayana Santos, Marco Prazeres, Cassia Righy and Fernando Augusto Bozza

    Citation: Annals of Intensive Care 2019 9:94

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  11. Content type: Review

    Metabolic acidosis is a disorder frequently encountered in emergency medicine and intensive care medicine. As literature has been enriched with new data concerning the management of metabolic acidosis, the Fre...

    Authors: Boris Jung, Mikaël Martinez, Yann-Erick Claessens, Michaël Darmon, Kada Klouche, Alexandre Lautrette, Jacques Levraut, Eric Maury, Mathieu Oberlin, Nicolas Terzi, Damien Viglino, Youri Yordanov, Pierre-Géraud Claret and Naïke Bigé

    Citation: Annals of Intensive Care 2019 9:92

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  12. Content type: Research

    Guidelines for the management of diabetic ketoacidosis (DKA) do not consider the type of underlying diabetes. We aimed to compare the occurrence of metabolic adverse events and the recovery time for DKA accord...

    Authors: Adrien Balmier, Fadia Dib, Arnaud Serret-Larmande, Etienne De Montmollin, Victorine Pouyet, Benjamin Sztrymf, Bruno Megarbane, Abirami Thiagarajah, Didier Dreyfuss, Jean-Damien Ricard and Damien Roux

    Citation: Annals of Intensive Care 2019 9:91

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  13. Content type: Research

    Recent European/American guidelines recommend noninvasive ventilation (NIV) as a first-line therapy to manage acute hypoxemic respiratory failure in immunocompromised patients. By contrast, NIV may have delete...

    Authors: Rémi Coudroy, Tài Pham, Florence Boissier, René Robert, Jean-Pierre Frat and Arnaud W. Thille

    Citation: Annals of Intensive Care 2019 9:90

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  14. Content type: Research

    The electrical activity of the crural diaphragm (Eadi), a surrogate of respiratory drive, can now be measured at the bedside in mechanically ventilated patients with a specific catheter. The expected range of ...

    Authors: Lise Piquilloud, François Beloncle, Jean-Christophe M. Richard, Jordi Mancebo, Alain Mercat and Laurent Brochard

    Citation: Annals of Intensive Care 2019 9:89

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  15. Content type: Research

    This study aims to assess the changes in lung aeration and ventilation during the first spontaneous breathing trial (SBT) and after extubation in a population of patients at risk of extubation failure.

    Authors: Federico Longhini, Jessica Maugeri, Cristina Andreoni, Chiara Ronco, Andrea Bruni, Eugenio Garofalo, Corrado Pelaia, Camilla Cavicchi, Sergio Pintaudi and Paolo Navalesi

    Citation: Annals of Intensive Care 2019 9:88

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  16. Content type: Research

    Information on the clinical, epidemiological and molecular characterization of human metapneumovirus in critically ill adult patients with severe community-acquired pneumonia (CAP) and the role of biomarkers i...

    Authors: Loreto Vidaur, Izarne Totorika, Milagrosa Montes, Diego Vicente, Jordi Rello and Gustavo Cilla

    Citation: Annals of Intensive Care 2019 9:86

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  17. Content type: Research

    To examine the impact of furosemide on mortality and the need for renal replacement therapy (RRT) in adult patients with acute kidney injury (AKI) based on current evidence.

    Authors: Łukasz J. Krzych and Piotr F. Czempik

    Citation: Annals of Intensive Care 2019 9:85

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  18. Content type: Correction

    After publication of the original article [1], we were notified that an author’s name has been incorrectly spelled. Andrei Hasting should be replaced with Andrei Hastings.

    Authors: Anupol Panitchote, Omar Mehkri, Andrei Hastings, Tarik Hanane, Sevag Demirjian, Heather Torbic, Eduardo Mireles-Cabodevila, Sudhir Krishnan and Abhijit Duggal

    Citation: Annals of Intensive Care 2019 9:84

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    The original article was published in Annals of Intensive Care 2019 9:74

  19. Content type: Research

    Noninvasive monitoring of maximal inspiratory and expiratory flows (MIF and MEF, respectively) by electrical impedance tomography (EIT) might enable early recognition of changes in the mechanical properties of...

    Authors: Tommaso Mauri, Elena Spinelli, Francesca Dalla Corte, Eleonora Scotti, Cecilia Turrini, Marta Lazzeri, Laura Alban, Marco Albanese, Donatella Tortolani, Yu-Mei Wang, Savino Spadaro, Jian-Xin Zhou, Antonio Pesenti and Giacomo Grasselli

    Citation: Annals of Intensive Care 2019 9:83

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  20. Content type: Research

    Venovenous extracorporeal membrane oxygenation (VV-ECMO) is associated with a significant morbidity. There is the need to investigate long-term cognitive outcome among ARDS survivors treated with VV-ECMO. We a...

    Authors: Aude Sylvestre, Mélanie Adda, François Maltese, Ariane Lannelongue, Florence Daviet, Gabriel Parzy, Benjamin Coiffard, Antoine Roch, Anderson Loundou, Karine Baumstarck and Laurent Papazian

    Citation: Annals of Intensive Care 2019 9:82

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  21. Content type: Research

    Although lung protection with low tidal volume and limited plateau pressure (Pplat) improves survival in acute respiratory distress syndrome patients (ARDS), the best way to set positive end-expiratory pressure (...

    Authors: Marie Bergez, Nicolas Fritsch, David Tran-Van, Tahar Saghi, Tan Bounkim, Ariane Gentile, Philippe Labadie, Bruno Fontaine, Alexandre Ouattara and Hadrien Rozé

    Citation: Annals of Intensive Care 2019 9:81

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  22. Content type: Correction

    Introduction: Burned patients are at high risk of yeast colonization and thus of invasive fungal infections, particularly to Candida (C.) spp., leading to an increase in morbidity and mortality. While pre-empt...

    Authors: Trabelsi Sonia, Hanachi Majdi, Bouchekoua Meriam, Aloui Dorsaf, Cheikhrouhou Sarra, Khaled Samira, Messadi Amen Allah and Thabet Lamia

    Citation: Annals of Intensive Care 2019 9:80

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    The original article was published in Annals of Intensive Care 2018 8:13

  23. Content type: Research

    Paediatric critical care practitioners often make use of pressure support (PS) to overcome the perceived imposed work of breathing (WOBimp) during an extubation readiness test (ERT). However, no paediatric dat...

    Authors: Jefta van Dijk, Robert G. T. Blokpoel, Alette A. Koopman, Sandra Dijkstra, Johannes G. M. Burgerhof and Martin C. J. Kneyber

    Citation: Annals of Intensive Care 2019 9:78

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  24. Content type: Review

    Delirium after surgery and in the intensive care unit (ICU) remains a challenge for patients, families, and caregivers. Over the years, many promising biomarkers have been investigated as potential instruments...

    Authors: Katharina Toft, Janna Tontsch, Salim Abdelhamid, Luzius Steiner, Martin Siegemund and Alexa Hollinger

    Citation: Annals of Intensive Care 2019 9:76

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  25. Content type: Research

    Non-tunneled hemodialysis catheters are currently used for critically ill patients with acute kidney injury requiring extracorporeal renal replacement therapy. Strategies to prevent catheter dysfunction and in...

    Authors: Jean-Pierre Quenot, Julie Helms, Abderrahmane Bourredjem, Auguste Dargent, Ferhat Meziani, Julio Badie, Gilles Blasco, Gaël Piton, Gilles Capellier, Chaouki Mezher, Jean-Michel Rebibou, Abdelouaid Nadji, Thomas Crepin, Saber Davide Barbar, Camille Fleck, Amélie Cransac…

    Citation: Annals of Intensive Care 2019 9:75

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  26. Content type: Research

    Acute kidney injury (AKI) is the most frequent extra-pulmonary organ failure in acute respiratory distress syndrome (ARDS). The objective of this study was to assess the factors associated with the development...

    Authors: Anupol Panitchote, Omar Mehkri, Andrei Hastings, Tarik Hanane, Sevag Demirjian, Heather Torbic, Eduardo Mireles-Cabodevila, Sudhir Krishnan and Abhijit Duggal

    Citation: Annals of Intensive Care 2019 9:74

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    The Correction to this article has been published in Annals of Intensive Care 2019 9:84

  27. Content type: Research

    The Surviving Sepsis Campaign and the American College of Critical Care Medicine guidelines have provided recommendations for the management of pediatric septic shock patients. We conducted a survey among the ...

    Authors: Luc Morin, Martin Kneyber, Nicolaas J. G. Jansen, Mark J. Peters, Etienne Javouhey, Simon Nadel, Graeme Maclaren, Luregn Jan Schlapbach and Pierre Tissieres

    Citation: Annals of Intensive Care 2019 9:73

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  28. Content type: Research

    The outcomes of weaning processes are not well known in pediatric patients, and the International Conference Classification on weaning from mechanical ventilation showed limited application. We evaluate the re...

    Authors: Ah Young Choi, Minji Kim, Esther Park, Meong Hi Son, Jeong-Am Ryu and Joongbum Cho

    Citation: Annals of Intensive Care 2019 9:72

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  29. Content type: Research

    For many survivors of acute respiratory distress syndrome (ARDS), the process from discharge from intensive care unit (ICU) to recovery is long and difficult. However, healthcare use after discharge from ICU h...

    Authors: Susanne Brandstetter, Frank Dodoo-Schittko, Magdalena Brandl, Sebastian Blecha, Thomas Bein and Christian Apfelbacher

    Citation: Annals of Intensive Care 2019 9:70

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  30. Content type: Review

    Fifteen recommendations and a therapeutic algorithm regarding the management of acute respiratory distress syndrome (ARDS) at the early phase in adults are proposed. The Grade of Recommendation Assessment, Dev...

    Authors: Laurent Papazian, Cécile Aubron, Laurent Brochard, Jean-Daniel Chiche, Alain Combes, Didier Dreyfuss, Jean-Marie Forel, Claude Guérin, Samir Jaber, Armand Mekontso-Dessap, Alain Mercat, Jean-Christophe Richard, Damien Roux, Antoine Vieillard-Baron and Henri Faure

    Citation: Annals of Intensive Care 2019 9:69

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  31. Content type: Research

    Sepsis is associated with systemic inflammation that may impact lipoprotein function. In particular, high-density lipoproteins (HDLs) that display pleiotropic protective roles may be dysfunctional in septic co...

    Authors: Sébastien Tanaka, Dévy Diallo, Sandrine Delbosc, Claire Genève, Nathalie Zappella, Jennyfer Yong-Sang, Jessica Patche, Anatole Harrois, Sophie Hamada, Erick Denamur, Philippe Montravers, Jacques Duranteau and Olivier Meilhac

    Citation: Annals of Intensive Care 2019 9:68

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  32. Content type: Research

    Anemia is one of the most common complications of sepsis. Sepsis-related anemia is associated mainly with inflammation. We aimed to observe the changes in the inflammatory anemia-associated parameters of patie...

    Authors: Yi Jiang, Feng-Quan Jiang, Fang Kong, Meng-Meng An, Bei-Bei Jin, Da Cao and Ping Gong

    Citation: Annals of Intensive Care 2019 9:67

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  33. Content type: Review

    Animal experiments are widely used in preclinical medical research with the goal of disease modeling and exploration of novel therapeutic approaches. In the context of sepsis and septic shock, the translation ...

    Authors: Antoine Guillon, Sebastien Preau, Jérôme Aboab, Eric Azabou, Boris Jung, Stein Silva, Julien Textoris, Fabrice Uhel, Dominique Vodovar, Lara Zafrani, Nicolas de Prost and Peter Radermacher

    Citation: Annals of Intensive Care 2019 9:66

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  34. Content type: Research

    Although no specific treatment facilitates renal tubular regeneration in acute kidney injury (AKI), the rapid increase in aging populations with more comorbidities and advances in critical care management are ...

    Authors: Subin Hwang, Hyejeong Park, Youngha Kim, Danbee Kang, Ho Suk Ku, Juhee Cho, Jung Eun Lee, Wooseong Huh, Eliseo Guallar, Gee Young Suh and Hye Ryoun Jang

    Citation: Annals of Intensive Care 2019 9:65

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  35. Content type: Research

    The mechanisms of organ failure during sepsis are not fully understood. The hypothesis of circulating factors has been suggested to explain septic myocardial dysfunction. We explored the biological coherence o...

    Authors: Keyvan Razazi, Florence Boissier, Mathieu Surenaud, Alexandre Bedet, Aurélien Seemann, Guillaume Carteaux, Nicolas de Prost, Christian Brun-Buisson, Sophie Hue and Armand Mekontso Dessap

    Citation: Annals of Intensive Care 2019 9:64

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  36. Content type: Research

    Early clinical data showed that some patients with vasodilatory shock are responsive to low doses of angiotensin II. The objective of this analysis was to compare clinical outcomes in patients requiring ≤ 5 ng kg

    Authors: Kealy R. Ham, David W. Boldt, Michael T. McCurdy, Laurence W. Busse, Raphael Favory, Michelle N. Gong, Ashish K. Khanna, Stefan N. Chock, Feng Zeng, Lakhmir S. Chawla, George F. Tidmarsh and Marlies Ostermann

    Citation: Annals of Intensive Care 2019 9:63

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  37. Content type: Research

    Immunocompromised critically ill patients constitute a population with the high risk of candidemia. This retrospective study aimed to assess the outcome of immunocompromised critically ill patients with candid...

    Authors: Etienne Ghrenassia, Djamel Mokart, Julien Mayaux, Alexandre Demoule, Imène Rezine, Lionel Kerhuel, Laure Calvet, Audrey De Jong, Elie Azoulay and Michael Darmon

    Citation: Annals of Intensive Care 2019 9:62

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  38. Content type: Research

    Femoral dP/dtmax (maximum rate of the arterial pressure increase during systole) measured by pulse contour analysis has been proposed as a surrogate of left ventricular (LV) dP/dtmax and as an estimator of LV sys...

    Authors: Sergi Vaquer, Denis Chemla, Jean-Louis Teboul, Umar Ahmad, Flora Cipriani, Joan Carles Oliva, Ana Ochagavia, Antonio Artigas, Francisco Baigorri and Xavier Monnet

    Citation: Annals of Intensive Care 2019 9:61

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  39. Content type: Research

    The actual effects of oxygen therapy on patients who have suffered a stroke are still unknown, and its recommendation as a routine measure in emergency services remains controversial. The aim of this study is ...

    Authors: Héctor Vargas López, Miguel Fernández Vivas, Rafael Núñez Ruiz, José Ros Martínez, Blanca García-Villalba Navaridas, Manuel García Villa, Cristina Llamas Lázaro, Rubén Jara Rubio, Ana Morales Ortiz, Laura Albert Lacal and Antonio Moreno Diéguez

    Citation: Annals of Intensive Care 2019 9:59

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  40. Content type: Review

    Muscular weakness developing from critical illness neuropathy, myopathy and muscle atrophy has been characterized as intensive care unit-acquired weakness (ICUAW). This entity occurs commonly during and after ...

    Authors: Paolo Formenti, Michele Umbrello, Silvia Coppola, Sara Froio and Davide Chiumello

    Citation: Annals of Intensive Care 2019 9:57

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  41. Content type: Review

    Although improving, the mortality from septic shock still remains high despite increased international awareness. As a consequence, much effort has focused on alternative treatment strategies in an effort to i...

    Authors: Patrick M. Honore, Eric Hoste, Zsolt Molnár, Rita Jacobs, Olivier Joannes-Boyau, Manu L. N. G. Malbrain and Lui G. Forni

    Citation: Annals of Intensive Care 2019 9:56

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  42. Content type: Research

    Results from preclinical studies suggest that age-dependent differences in host defense and the pulmonary renin–angiotensin system (RAS) are responsible for observed differences in epidemiology of acute respir...

    Authors: Laura R. Schouten, Anton H. van Kaam, Franziska Kohse, Floor Veltkamp, Lieuwe D. Bos, Friso M. de Beer, Roosmarijn T. van Hooijdonk, Janneke Horn, Marleen Straat, Esther Witteveen, Gerie J. Glas, Luuk Wieske, Lonneke A. van Vught, Maryse A. Wiewel, Sarah A. Ingelse, Bart Cortjens…

    Citation: Annals of Intensive Care 2019 9:55

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