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  1. Combining oxygen facemask with apnoeic oxygenation using high-flow-nasal-oxygen (HFNO) for preoxygenation in the operating room has not been studied against standard oxygen facemask alone. We hypothesized that...

    Authors: Samir Jaber, Audrey De Jong, Maximilian S. Schaefer, Jiaqiang Zhang, Xiaowen Ma, Xinrui Hao, Shujing Zhou, Shang Lv, Valerie Banner-Goodspeed, Xiuhua Niu, Thomas Sfara and Daniel Talmor
    Citation: Annals of Intensive Care 2023 13:26
  2. To evaluate the differences in the clinical characteristics and severity of lung impairment, assessed by quantitative lung CT scan, between vaccinated and non-vaccinated hospitalized patients with COVID-19; an...

    Authors: Davide Chiumello, Alessandro Tavelli, Lorenzo Serio, Sara De Benedittis, Tommaso Pozzi, Roberta Maj, Mara Velati, Serena Brusatori, Rosanna D’Albo, Carmelo Zinnato, Giulia Marchetti, Luigi Camporota, Silvia Coppola and Antonella D’Arminio Monforte
    Citation: Annals of Intensive Care 2023 13:24
  3. The concept of acute kidney injury (AKI) substages has been recommended to better phenotype AKI and identify high-risk patient groups and therefore improve the diagnostic accuracy of AKI. However, there remain...

    Authors: Jiao Chen, Zhen Jiang, Hui Huang, Min Li, Zhenjiang Bai, Yuxian Kuai, Lin Wei, Ning Liu, Xiaozhong Li, Guoping Lu and Yanhong Li
    Citation: Annals of Intensive Care 2023 13:23
  4. The rise in antimicrobial resistance is a global threat responsible for about 33,000 deaths in 2015 with a particular concern for extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-E) and has led t...

    Authors: Erwann Cariou, Romain Griffier, Arthur Orieux, Stein Silva, Stanislas Faguer, Thierry Seguin, Saad Nseir, Emmanuel Canet, Arnaud Desclaux, Bertrand Souweine, Kada Klouche, Olivier Guisset, Jerome Pillot, Walter Picard, Tahar Saghi, Pierre Delobel…
    Citation: Annals of Intensive Care 2023 13:22
  5. Unlike other viruses, the pathogenicity of human metapneumovirus (hMPV) in adults remains uncertain. To address this question, a retrospective monocentric cohort including all patients admitted to ICU with hMP...

    Authors: Natacha Kapandji, Michael Darmon, Sandrine Valade, Maud Salmona, Jérôme Legoff, Lara Zafrani, Elie Azoulay and Virginie Lemiale
    Citation: Annals of Intensive Care 2023 13:21
  6. Authors: Diane Naouri, Albert Vuagnat, Gaëtan Beduneau, Martin Dres, Tai Pham, Alain Mercat, Alain Combes, Alexandre Demoule, Antoine Kimmoun, Matthieu Schmidt and Matthieu Jamme
    Citation: Annals of Intensive Care 2023 13:20

    The original article was published in Annals of Intensive Care 2023 13:2

  7. In France, physician-assisted suicide or euthanasia are not legal but are still debated. French intensive care unit (ICU) health care workers (HCWs) have an insider’s perspective on the global quality of the p...

    Authors: Mathieu Acquier, Alexandre Boyer, Bertrand Guidet, Alexandre Lautrette, Jean Reignier, Guillaume Thiery and René Robert
    Citation: Annals of Intensive Care 2023 13:19
  8. The extent of the consequences of an episode of severe acute kidney injury (AKI) on long-term outcome of critically ill patients remain debated. We conducted a prospective follow-up of patients included in a l...

    Authors: Khalil Chaïbi, Franck Ehooman, Bertrand Pons, Laurent Martin-Lefevre, Eric Boulet, Alexandre Boyer, Guillaume Chevrel, Nicolas Lerolle, Dorothée Carpentier, Nicolas de Prost, Alexandre Lautrette, Anne Bretagnol, Julien Mayaux, Saad Nseir, Bruno Megarbane, Marina Thirion…
    Citation: Annals of Intensive Care 2023 13:18
  9. Profound lymphopenia is an independent predictor of adverse clinical outcomes in sepsis. Interleukin-7 (IL-7) is essential for lymphocyte proliferation and survival. A previous phase II study showed that CYT10...

    Authors: Thomas Daix, Armelle Mathonnet, Scott Brakenridge, Pierre-François Dequin, Jean-Paul Mira, Frederique Berbille, Michel Morre, Robin Jeannet, Teresa Blood, Jacqueline Unsinger, Jane Blood, Andrew Walton, Lyle L. Moldawer, Richard Hotchkiss and Bruno François
    Citation: Annals of Intensive Care 2023 13:17
  10. The use of citrate, through reversible binding of calcium, has become the preferred choice for anticoagulation in continuous renal replacement therapy in the critically ill patient. Though generally considered...

    Authors: Willem Boer, Walter Verbrugghe, Eric Hoste, Rita Jacobs and Philippe G. Jorens
    Citation: Annals of Intensive Care 2023 13:16
  11. Severe hypothyroidism (SH) is a rare but life-threatening endocrine emergency. Only a few data are available on its management and outcomes of the most severe forms requiring ICU admission. We aimed to describ...

    Authors: Simon Bourcier, Maxime Coutrot, Alexis Ferré, Nicolas Van Grunderbeeck, Julien Charpentier, Sami Hraiech, Elie Azoulay, Saad Nseir, Nadia Aissaoui, Jonathan Messika, Pierre Fillatre, Romain Persichini, Serge Carreira, Alexandre Lautrette, Clément Delmas, Nicolas Terzi…
    Citation: Annals of Intensive Care 2023 13:15
  12. A recent landmark randomized controlled trial (RCT) in septic patients demonstrated an increased risk of death and persistent organ dysfunction with intravenous Vitamin C (IVVC) monotherapy, which represents a...

    Authors: Zheng-Yii Lee, Luis Ortiz-Reyes, Charles Chin Han Lew, M. Shahnaz Hasan, Lu Ke, Jayshil J. Patel, Christian Stoppe and Daren K. Heyland
    Citation: Annals of Intensive Care 2023 13:14
  13. Unique blood culture (UBC) has been proposed to limit the number of venipuncture and to decrease the risk of BC contaminations (BCC) without affecting their yield. We hypothesized that a multi-faceted program ...

    Authors: Rafael Mahieu, Carole Lemarié, Delphine Douillet, Alain Mercat, Hélène Cormier, Matthieu Eveillard, Vincent Dubée, Jérémie Riou and Achille Kouatchet
    Citation: Annals of Intensive Care 2023 13:13
  14. Thromboembolism is more common in patients with critical COVID-19 than in other critically ill patients, and inflammation has been proposed as a possible mechanism. The aim of this study was to investigate if ...

    Authors: Sandra Jonmarker, Felix Alarcón, Jacob Litorell, Anders Granholm, Eva Joelsson Alm, Michelle Chew, Lene Russell, Sarah Weihe, Emilie Kabel Madsen, Nick Meier, Jens Wolfgang Leistner, Johan Mårtensson, Jacob Hollenberg, Anders Perner, Maj-Brit Nørregaard Kjær, Marie Warrer Munch…
    Citation: Annals of Intensive Care 2023 13:12
  15. Sepsis prognosis correlates with antibiotic adequacy at the early phase. This adequacy is dependent on antibacterial spectrum, bacterial resistance profile and antibiotic dosage. Optimal efficacy of beta-lacta...

    Authors: Damien Roux, Nicolas Benichou, David Hajage, Laurent Martin-Lefèvre, Nicolas de Prost, Nicolas Lerolle, Dimitri Titeca-Beauport, Eric Boulet, Julien Mayaux, Bruno Mégarbane, Khaoula Mahjoub, Dorothée Carpentier, Saad Nseir, Florence Tubach, Jean-Damien Ricard, Didier Dreyfuss…
    Citation: Annals of Intensive Care 2023 13:11
  16. Electroencephalography (EEG) is recommended for the practical approach to the diagnosis and prognosis of encephalitis. We aimed to investigate the prognostic value of standard EEG (stdEEG) in adult patients with ...

    Authors: Lina Jeantin, Claire Dupuis, Geoffroy Vellieux, Pierre Jaquet, Etienne de Montmollin, Jean-François Timsit and Romain Sonneville
    Citation: Annals of Intensive Care 2023 13:10
  17. Intensivists target different blood pressure component values to manage intensive care unit (ICU) patients with sepsis. We aimed to evaluate the relationship between individual blood pressure components and or...

    Authors: Ashish K. Khanna, Takahiro Kinoshita, Annamalai Natarajan, Emma Schwager, Dustin D. Linn, Junzi Dong, Erina Ghosh, Francesco Vicario and Kamal Maheshwari
    Citation: Annals of Intensive Care 2023 13:9
  18. The pivotal ASPECT-NP trial showed ceftolozane/tazobactam was non-inferior to meropenem for the treatment of ventilated hospital-acquired/ventilator-associated bacterial pneumonia (vHABP/VABP). Here, we evalua...

    Authors: Ignacio Martin-Loeches, Andrew F. Shorr, Richard G. Wunderink, Marin H. Kollef, Jean-François Timsit, Brian Yu, Jennifer A. Huntington, Erin Jensen and Christopher J. Bruno
    Citation: Annals of Intensive Care 2023 13:8
  19. The past years have witnessed dramatic changes in the population admitted to the intensive care unit (ICU). Older and sicker patients are now commonly treated in this setting due to the newly available sophist...

    Authors: João Gonçalves-Pereira, André Oliveira, Tatiana Vieira, Ana Rita Rodrigues, Maria João Pinto, Sara Pipa, Ana Martinho, Sofia Ribeiro and José-Artur Paiva
    Citation: Annals of Intensive Care 2023 13:7
  20. The aim of this study was to assess the usefulness of adding thoracic CT to abdominal CT in intensive care unit (ICU) patients with signs of infection after abdominopelvic surgery.

    Authors: Heiner Nebelung, Natalie Wotschel, Hanns-Christoph Held, Johanna Kirchberg, Jürgen Weitz, Christoph Georg Radosa, Michael Laniado, Ralf-Thorsten Hoffmann and Verena Plodeck
    Citation: Annals of Intensive Care 2023 13:6
  21. The anatomic site for central venous catheter insertion influences the risk of central venous catheter-related intravascular complications. We developed and validated a predictive score of required catheter dw...

    Authors: Jeanne Iachkine, Niccolò Buetti, Harm-Jan de Grooth, Anaïs R. Briant, Olivier Mimoz, Bruno Mégarbane, Jean-Paul Mira, Xavier Valette, Cédric Daubin, Damien du Cheyron, Leonard A. Mermel, Jean-François Timsit and Jean-Jacques Parienti
    Citation: Annals of Intensive Care 2023 13:5
  22. Sepsis and septic shock are frequently accompanied by coagulopathy. Since the sepsis-induced coagulopathy (SIC) score was first described, subsequent studies from Asia revealed a SIC prevalence of 40–60%. In E...

    Authors: Thomas Schmoch, Patrick Möhnle, Markus A. Weigand, Josef Briegel, Michael Bauer, Frank Bloos, Patrick Meybohm, Didier Keh, Markus Löffler, Gunnar Elke, Thorsten Brenner and Holger Bogatsch
    Citation: Annals of Intensive Care 2023 13:3
  23. Studies regarding coronavirus disease 2019 (COVID-19) were mainly performed in the initial wave, but some small-scale data points to prognostic differences for patients in successive waves. We therefore aimed ...

    Authors: Diane Naouri, Albert Vuagnat, Gaëtan Beduneau, Martin Dres, Tai Pham, Alain Mercat, Alain Combes, Alexandre Demoule, Antoine Kimmoun, Matthieu Schmidt and Matthieu Jamme
    Citation: Annals of Intensive Care 2023 13:2

    The Correction to this article has been published in Annals of Intensive Care 2023 13:20

  24. Adverse reactions, especially nephrotoxicity, are great concerns of intravenous colistin treatment. The role of substitutive nebulized colistin in treating nosocomial pneumonia caused by carbapenem-resistant G...

    Authors: Jia-Yih Feng, Jhong-Ru Huang, Chang-Ching Lee, Yen-Han Tseng, Sheng-Wei Pan, Yuh-Min Chen and Kuang-Yao Yang
    Citation: Annals of Intensive Care 2023 13:1
  25. Auto-antibodies (auto-Abs) neutralizing type I interferons (IFN) have been found in about 15% of critical cases COVID-19 pneumonia and less than 1% of mild or asymptomatic cases. Determining whether auto-Abs i...

    Authors: Romain Arrestier, Paul Bastard, Thibaut Belmondo, Guillaume Voiriot, Tomas Urbina, Charles-Edouard Luyt, Adrian Gervais, Lucy Bizien, Lauriane Segaux, Mariem Ben Ahmed, Raphaël Bellaïche, Taï Pham, Zakaria Ait-Hamou, Damien Roux, Raphael Clere-Jehl, Elie Azoulay…
    Citation: Annals of Intensive Care 2022 12:121
  26. While frailty is a known predictor of adverse outcomes in older patients, its effect in younger populations is unknown. This prospective observational study was conducted in a tertiary-level mixed ICU to asses...

    Authors: Lina De Geer, Mats Fredrikson and Michelle S. Chew
    Citation: Annals of Intensive Care 2022 12:120
  27. Neurological complications are associated with poor outcome in patients with infective endocarditis (IE). Although guidelines recommend systematic brain imaging in the evaluation of IE patients, the associatio...

    Authors: Thomas Rambaud, Etienne de Montmollin, Pierre Jaquet, Augustin Gaudemer, Eric Mariotte, Sonia Abid, Marylou Para, Claire Cimadevilla, Bernard Iung, Xavier Duval, Michel Wolff, Lila Bouadma, Jean-François Timsit and Romain Sonneville
    Citation: Annals of Intensive Care 2022 12:119
  28. Acute kidney injury (AKI) is common in critically ill patients with coronavirus disease-19 (COVID-19). We aimed to explore the changes in AKI epidemiology between the first and the second COVID wave in the Uni...

    Authors: Nuttha Lumlertgul, Eleanor Baker, Emma Pearson, Kathryn V. Dalrymple, Jacqueline Pan, Anup Jheeta, Kittisak Weerapolchai, Yanzhong Wang, Richard Leach, Nicholas A. Barrett and Marlies Ostermann
    Citation: Annals of Intensive Care 2022 12:118
  29. Although risk factors of occlusive acute mesenteric ischemia are well known, triggering factors of nonocclusive mesenteric ischemia (NOMI) remain unclear. Alongside to the known risk factors for NOMI, the role...

    Authors: Anhum Konan, Gael Piton, Maxime Ronot, Youness Hassoun, Hadrien Winiszewski, Guillaume Besch, Alexandre Doussot, Eric Delabrousse and Paul Calame
    Citation: Annals of Intensive Care 2022 12:117
  30. Acute hypoxemic respiratory failure (AHRF) is a leading concern in critically ill patients. Experimental and clinical data suggest that early sedation with volatile anesthestics may improve arterial oxygenatio...

    Authors: Tobias Becher, Andreas Meiser, Ulf Guenther, Martin Bellgardt, Jan Wallenborn, Klaus Kogelmann, Hendrik Bracht, Andreas Falthauser, Jonas Nilsson, Peter Sackey and Patrick Kellner
    Citation: Annals of Intensive Care 2022 12:116
  31. Necrotizing skin and soft tissue infections (NSTIs) are rare but serious and rapidly progressive infections characterized by necrosis of subcutaneous tissue, fascia and even muscle. The care pathway of patient...

    Authors: Camille Windsor, Camille Hua, Quentin De Roux, Anatole Harrois, Nadia Anguel, Philippe Montravers, Antoine Vieillard-Baron, Jean-Paul Mira, Tomas Urbina, Stéphane Gaudry, Matthieu Turpin, Charles Damoisel, Djillali Annane, Jean-Damien Ricard, Barbara Hersant, Armand Mekontso Dessap…
    Citation: Annals of Intensive Care 2022 12:115
  32. The literature is unresolved on whether female receive advanced cardiac life support less than do male and on whether female have a survival advantage over male after cardiopulmonary resuscitation.

    Authors: Ines Lakbar, Mariachiara Ippolito, Aviv Nassiri, Louis Delamarre, Philippe Tadger, Marc Leone and Sharon Einav
    Citation: Annals of Intensive Care 2022 12:114
  33. Non-occlusive mesenteric ischemia (NOMI) is a challenging diagnosis and is associated with extremely high mortality in critically ill patients, particularly due to delayed diagnosis and when complicated by int...

    Authors: Simon Bourcier, Guillaume Ulmann, Matthieu Jamme, Guillaume Savary, Marine Paul, Sarah Benghanem, Jean-Rémi Lavillegrand, Matthieu Schmidt, Charles-Edouard Luyt, Eric Maury, Alain Combes, Frédéric Pène, Nathalie Neveux and Alain Cariou
    Citation: Annals of Intensive Care 2022 12:113
  34. The implication of sepsis-induced cardiomyopathy (SIC) to prognosis is controversial, and its association with mortality at different stages remains unclear. We conducted a systematic review and meta-analysis ...

    Authors: Yu-Min Lin, Mei-Chuan Lee, Han Siong Toh, Wei-Ting Chang, Sih-Yao Chen, Fang-Hsiu Kuo, Hsin-Ju Tang, Yi-Ming Hua, Dongmei Wei, Jesus Melgarejo, Zhen-Yu Zhang and Chia-Te Liao
    Citation: Annals of Intensive Care 2022 12:112
  35. About 80% of patients resuscitated from CA are comatose at ICU admission and nearly 50% of survivors are still unawake at 72 h. Predicting neurological outcome of these patients is important to provide correct...

    Authors: Sarah Benghanem, Estelle Pruvost-Robieux, Eléonore Bouchereau, Martine Gavaret and Alain Cariou
    Citation: Annals of Intensive Care 2022 12:111
  36. The ratio of SpO2/FiO2 to respiratory rate (ROX) index is commonly used to predict the failure of high-flow nasal cannula. However, its predictive power for noninvasive ventilation (NIV) failure is unclear.

    Authors: Jun Duan, Juhua Yang, Lei Jiang, Linfu Bai, Wenhui Hu, Weiwei Shu, Ke Wang and Fuxun Yang
    Citation: Annals of Intensive Care 2022 12:110
  37. Prone positioning is currently applied in time-limited daily sessions up to 24 h which determines that most patients require several sessions. Although longer prone sessions have been reported, there is scarce...

    Authors: Rodrigo A. Cornejo, Jorge Montoya, Abraham I. J. Gajardo, Jerónimo Graf, Leyla Alegría, Romyna Baghetti, Anita Irarrázaval, César Santis, Nicolás Pavez, Sofía Leighton, Vinko Tomicic, Daniel Morales, Carolina Ruiz, Pablo Navarrete, Patricio Vargas, Roberto Gálvez…
    Citation: Annals of Intensive Care 2022 12:109
  38. Frailty and delirium are prevalent among older adults admitted to the intensive care unit (ICU) and associated with adverse outcomes; however, their relationships have not been extensively explored. This study...

    Authors: Berhe W. Sahle, David Pilcher, Edward Litton, Richard Ofori-Asenso, Karlheinz Peter, James McFadyen and Tracey Bucknall
    Citation: Annals of Intensive Care 2022 12:108
  39. β-lactams are the main antibiotics used against wild-type AmpC-producing Enterobacterales (wtAE). However, they may fail or select AmpC-overproducing mutants. Our aim was to assess factors associated with clin...

    Authors: Roman Mounier, Ronan Le Guen, Paul-Louis Woerther, Mathieu Nacher, Clément Bonnefon, Nicolas Mongardon, Olivier Langeron, Eric Levesque, Séverine Couffin, Stéphanie Houcke, Michel Wolff, Ariane Roujansky, Caroline Schimpf, Armand Mekontso Dessap, Fabrice Cook, Keyvan Razazi…
    Citation: Annals of Intensive Care 2022 12:107
  40. Since the response to lung recruitment varies greatly among patients receiving mechanical ventilation, lung recruitability should be assessed before recruitment maneuvers. The pressure–volume curve (PV curve) ...

    Authors: Ryuichi Nakayama, Naofumi Bunya, Shinshu Katayama, Yuya Goto, Yusuke Iwamoto, Kenshiro Wada, Keishi Ogura, Naoya Yama, Shintaro Takatsuka, Masumi Kishimoto, Kanako Takahashi, Ryuichiro Kakizaki, Keigo Sawamoto, Shuji Uemura, Keisuke Harada and Eichi Narimatsu
    Citation: Annals of Intensive Care 2022 12:106
  41. Extracorporeal blood purification (EBP) treatments may be used in patients with sepsis and related conditions to mitigate toxic systemic inflammation, prevent or reverse vital organ injury, and improve outcome...

    Authors: James Matson, Paul Lange, Patrick M. Honore and Kevin K. Chung
    Citation: Annals of Intensive Care 2022 12:105
  42. Right ventricular (RV) dysfunction has been commonly reported in patients with Coronavirus disease 2019 (COVID-19), and is associated with mortality in mixed cohorts of patients requiring and not requiring inv...

    Authors: James McErlane, Philip McCall, Jennifer Willder, Colin Berry and Ben Shelley
    Citation: Annals of Intensive Care 2022 12:104
  43. Clinicians monitor mechanical ventilatory support using airway pressures—primarily the plateau and driving pressure, which are considered by many to determine the safety of the applied tidal volume. These airw...

    Authors: John Selickman and John J. Marini
    Citation: Annals of Intensive Care 2022 12:103
  44. Dexamethasone is recommended for COVID-19 patients who require oxygen therapy. However, its effectiveness in reducing mortality and intubation, and its safety, remain debated. We aimed to investigate whether d...

    Authors: Matthieu Raymond, Aurélie Le Thuaut, Pierre Asfar, Cédric Darreau, Florian Reizine, Gwenhaël Colin, Charly Dano, Julien Lorber, Baptiste Hourmant, Agathe Delbove, Aurélien Frérou, Jean Morin, Pierre Yves Egreteau, Philippe Seguin, Jean Reignier, Jean-Baptiste Lascarrou…
    Citation: Annals of Intensive Care 2022 12:102
  45. Etoposide remains the cornerstone of symptomatic management of critically ill patients with secondary hemophagocytic syndrome (sHS). Risk of healthcare-associated infections (HAIs) in this setting with etoposi...

    Authors: Thibault Dupont, Michael Darmon, Eric Mariotte, Virginie Lemiale, Jehane Fadlallah, Adrien Mirouse, Lara Zafrani, Elie Azoulay and Sandrine Valade
    Citation: Annals of Intensive Care 2022 12:101
  46. Fluid creep, including fluids administered as drug diluents and for the maintenance of catheter patency, is the major source of fluid intake in critically ill patients. Although hypoxemia may lead to fluid res...

    Authors: Masaaki Sakuraya, Shodai Yoshihiro, Kazuto Onozuka, Akihiro Takaba, Hideto Yasuda, Nobuaki Shime, Yuki Kotani, Yuki Kishihara, Natsuki Kondo, Kosuke Sekine and Keita Morikane
    Citation: Annals of Intensive Care 2022 12:100
  47. For mechanically ventilated critically ill COVID-19 patients, prone positioning has quickly become an important treatment strategy, however, prone positioning is labor intensive and comes with potential advers...

    Authors: Tariq A. Dam, Luca F. Roggeveen, Fuda van Diggelen, Lucas M. Fleuren, Ameet R. Jagesar, Martijn Otten, Heder J. de Vries, Diederik Gommers, Olaf L. Cremer, Rob J. Bosman, Sander Rigter, Evert-Jan Wils, Tim Frenzel, Dave A. Dongelmans, Remko de Jong, Marco A. A. Peters…
    Citation: Annals of Intensive Care 2022 12:99
  48. Outcomes of postresuscitation shock after cardiac arrest can be affected by targeted temperature management (TTM). A post hoc analysis of the “TTM1 trial” suggested higher mortality with hypothermia at 33 °C. ...

    Authors: Ines Ziriat, Aurélie Le Thuaut, Gwenhael Colin, Hamid Merdji, Guillaume Grillet, Patrick Girardie, Bertrand Souweine, Pierre-François Dequin, Thierry Boulain, Jean-Pierre Frat, Pierre Asfar, Bruno Francois, Mickael Landais, Gaëtan Plantefeve, Jean-Pierre Quenot, Jean-Charles Chakarian…
    Citation: Annals of Intensive Care 2022 12:96

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