Skip to content



Page 4 of 14

  1. Content type: Research

    Identifying patients at high risk of post-extubation acute respiratory failure requiring respiratory or mechanical cough assistance remains challenging. Here, our primary aim was to evaluate the accuracy of ea...

    Authors: Nicolas Terzi, Frédéric Lofaso, Romain Masson, Pascal Beuret, Hervé Normand, Edith Dumanowski, Line Falaize, Bertrand Sauneuf, Cédric Daubin, Jennifer Brunet, Djillali Annane, Jean-Jacques Parienti and David Orlikowski

    Citation: Annals of Intensive Care 2018 8:18

    Published on:

  2. Content type: Research

    To explore potential design for pharmacogenomics trials in sepsis, we investigate the interaction between pharmacogenomic biomarkers and response to drotrecogin alfa (activated) (DrotAA). This trial was desig...

    Authors: Djillali Annane, Jean-Paul Mira, Lorraine B. Ware, Anthony C. Gordon, Charles J. Hinds, David C. Christiani, Jonathan Sevransky, Kathleen Barnes, Timothy G. Buchman, Patrick J. Heagerty, Robert Balshaw, Nadia Lesnikova, Karen de Nobrega, Hugh F. Wellman, Mauricio Neira, Alexandra D. J. Mancini…

    Citation: Annals of Intensive Care 2018 8:16

    Published on:

  3. Content type: Research

    Hypoxic hepatitis (HH) is a type of acute hepatic injury that is histologically characterized by centrilobular liver cell necrosis and that is caused by insufficient oxygen delivery to the hepatocytes. Typical...

    Authors: Astrid Van den broecke, Laura Van Coile, Alexander Decruyenaere, Kirsten Colpaert, Dominique Benoit, Hans Van Vlierberghe and Johan Decruyenaere

    Citation: Annals of Intensive Care 2018 8:15

    Published on:

  4. Content type: Research

    Assessment of maximum respiratory pressures is a common practice in intensive care because it can predict the success of weaning from ventilation. However, the reliability of measurements through an intubation...

    Authors: Clément Medrinal, Guillaume Prieur, Yann Combret, Aurora Robledo Quesada, Tristan Bonnevie, Francis Edouard Gravier, Eric Frenoy, Olivier Contal and Bouchra Lamia

    Citation: Annals of Intensive Care 2018 8:14

    Published on:

  5. Content type: Research

    To explore the feasibility of transcutaneous electromyographic respiratory muscle recordings to automatically quantify the synchronicity of patient–ventilator interaction in the pediatric intensive care unit.

    Authors: Alette A. Koopman, Robert G. T. Blokpoel, Leo A. van Eykern, Frans H. C. de Jongh, Johannes G. M. Burgerhof and Martin C. J. Kneyber

    Citation: Annals of Intensive Care 2018 8:12

    Published on:

  6. Content type: Research

    Weaning protocols expedite extubation in mechanically ventilated patients, yet the literature investigating the application in tracheostomized patients remains scarce. The primary objective of this parallel ra...

    Authors: Nazzareno Fagoni, Simone Piva, Elena Peli, Fabio Turla, Elisabetta Pecci, Livio Gualdoni, Bertilla Fiorese, Frank Rasulo and Nicola Latronico

    Citation: Annals of Intensive Care 2018 8:11

    Published on:

  7. Content type: Research

    Stool cultures for Campylobacter, Salmonella and Shigella and/or Yersinia spp. are frequently ordered in critically ill patients with diarrhea. The aim of this study is to analyze the diagnostic yield in a large ...

    Authors: Carolin F. Manthey, Darja Dranova, Martin Christner, Laura Berneking, Stefan Kluge, Ansgar W. Lohse and Valentin Fuhrmann

    Citation: Annals of Intensive Care 2018 8:10

    Published on:

  8. Content type: Research

    Statins can exert pleiotropic anti-inflammatory, vascular protective and anticoagulant effects, which in theory could improve the dysregulated host response during sepsis. We aimed to determine the association...

    Authors: Maryse A. Wiewel, Brendon P. Scicluna, Lonneke A. van Vught, Arie J. Hoogendijk, Aeilko H. Zwinderman, René Lutter, Janneke Horn, Olaf L. Cremer, Marc J. Bonten, Marcus J. Schultz and Tom van der Poll

    Citation: Annals of Intensive Care 2018 8:9

    Published on:

  9. Content type: Research

    Furosemide responsiveness (FR) is determined by urine output after furosemide administration and has recently been evaluated as a furosemide stress test (FST) for predicting severe acute kidney injury (AKI) pr...

    Authors: Ryo Matsuura, Yohei Komaru, Yoshihisa Miyamoto, Teruhiko Yoshida, Kohei Yoshimoto, Rei Isshiki, Kengo Mayumi, Tetsushi Yamashita, Yoshifumi Hamasaki, Masaomi Nangaku, Eisei Noiri, Naoto Morimura and Kent Doi

    Citation: Annals of Intensive Care 2018 8:8

    Published on:

  10. Content type: Research

    There is no consensus on the management of anticoagulation during extracorporeal membrane oxygenation (ECMO). ECMO is currently burdened by a high rate of hemostatic complications, possibly associated with ina...

    Authors: Mauro Panigada, Giacomo E. Iapichino, Matteo Brioni, Giovanna Panarello, Alessandro Protti, Giacomo Grasselli, Giovanna Occhipinti, Cristina Novembrino, Dario Consonni, Antonio Arcadipane, Luciano Gattinoni and Antonio Pesenti

    Citation: Annals of Intensive Care 2018 8:7

    Published on:

  11. Content type: Research

    To evaluate the efficacy of using internal jugular vein variability (IJVV) as an index of fluid responsiveness in mechanically ventilated patients after cardiac surgery.

    Authors: Guo-guang Ma, Guang-wei Hao, Xiao-mei Yang, Du-ming Zhu, Lan Liu, Hua Liu, Guo-wei Tu and Zhe Luo

    Citation: Annals of Intensive Care 2018 8:6

    Published on:

  12. Content type: Research

    The acute respiratory distress syndrome (ARDS) is a life-threatening condition. In special situations, these critically ill patients must be transferred to specialized centers for escalating treatment. The aim...

    Authors: Sebastian Blecha, Frank Dodoo-Schittko, Susanne Brandstetter, Magdalena Brandl, Michael Dittmar, Bernhard M. Graf, Christian Karagiannidis, Christian Apfelbacher and Thomas Bein

    Citation: Annals of Intensive Care 2018 8:5

    Published on:

  13. Content type: Research

    Hyperglycaemia is commonplace in the adult intensive care unit (ICU), associated with increased morbidity and mortality. Effective glycaemic control (GC) can reduce morbidity and mortality, but has proven diff...

    Authors: Kent W. Stewart, J. Geoffrey Chase, Christopher G. Pretty and Geoffrey M. Shaw

    Citation: Annals of Intensive Care 2018 8:4

    Published on:

  14. Content type: Research

    Middle East respiratory syndrome (MERS) is caused by a coronavirus (MERS‐CoV) and is characterized by hypoxemic respiratory failure. The objective of this study is to compare the outcomes of MERS-CoV patients ...

    Authors: Mohammed S. Alshahrani, Anees Sindi, Fayez Alshamsi, Awad Al-Omari, Mohamed El Tahan, Bayan Alahmadi, Ahmed Zein, Naif Khatani, Fahad Al-Hameed, Sultan Alamri, Mohammed Abdelzaher, Amenah Alghamdi, Faisal Alfousan, Adel Tash, Wail Tashkandi, Rajaa Alraddadi…

    Citation: Annals of Intensive Care 2018 8:3

    Published on:

  15. Content type: Research

    Cardiac dysfunction is a common cause of weaning failure. Weaning shares some similarities with a cardiac stress test and may challenge active phases of the cardiac cycle-like ventricular contractility and rel...

    Authors: Ferran Roche-Campo, Alexandre Bedet, Emmanuel Vivier, Laurent Brochard and Armand Mekontso Dessap

    Citation: Annals of Intensive Care 2018 8:2

    Published on:

  16. Content type: Research

    The early prediction of the severity of acute pancreatitis still represents a challenge for clinicians. Experimental studies have revealed the generation of specific halogenated lipids, in particular oleic aci...

    Authors: Enrique de-Madaria, Xavier Molero, Laia Bonjoch, Josefina Casas, Karina Cárdenas-Jaén, Andrea Montenegro and Daniel Closa

    Citation: Annals of Intensive Care 2018 8:1

    Published on:

  17. Content type: Research

    We aimed (1) to describe the characteristics of patient–ventilator asynchrony in a population of critically ill children, (2) to describe the risk factors associated with patient–ventilator asynchrony, and (3)...

    Authors: Guillaume Mortamet, Alexandrine Larouche, Laurence Ducharme-Crevier, Olivier Fléchelles, Gabrielle Constantin, Sandrine Essouri, Amélie-Ann Pellerin-Leblanc, Jennifer Beck, Christer Sinderby, Philippe Jouvet and Guillaume Emeriaud

    Citation: Annals of Intensive Care 2017 7:122

    Published on:

  18. Content type: Research

    Left ventricular diastolic dysfunction is suggested to be associated with higher mortality in severe sepsis and septic shock, yet the methods of diagnosis described in the literature are often inconsistent. Th...

    Authors: David J. Clancy, Timothy Scully, Michel Slama, Stephen Huang, Anthony S. McLean and Sam R. Orde

    Citation: Annals of Intensive Care 2017 7:121

    Published on:

  19. Content type: Research

    Among intensive care unit (ICU) patients with acute respiratory distress syndrome (ARDS), apart from acute cor pulmonale (ACP), the frequency and prognostic impact of basic critical care echocardiography (BCCE...

    Authors: Kay Choong See, Jeffrey Ng, Wen Ting Siow, Venetia Ong and Jason Phua

    Citation: Annals of Intensive Care 2017 7:120

    Published on:

  20. Content type: Research

    Patients with malignant haematological disease and especially those who require intensive care have an increased risk of bleeding and thrombosis, but none of these data were obtained in ICU patients only. We a...

    Authors: Lene Russell, Lars Broksø Holst, Lars Kjeldsen, Jakob Stensballe and Anders Perner

    Citation: Annals of Intensive Care 2017 7:119

    Published on:

  21. Content type: Research

    Septic shock-induced disseminated intravascular coagulation is responsible for increased occurrence of multiple organ dysfunction and mortality. Immunothrombosis-induced coagulopathy may contribute to hypercoa...

    Authors: Julie Helms, Raphaël Clere-Jehl, Elsa Bianchini, Pierrick Le Borgne, Mélanie Burban, Fatiha Zobairi, Jean-Luc Diehl, Lelia Grunebaum, Florence Toti, Ferhat Meziani and Delphine Borgel

    Citation: Annals of Intensive Care 2017 7:118

    Published on:

  22. Content type: Review

    Host infection by a micro-organism triggers systemic inflammation, innate immunity and complement pathways, but also haemostasis activation. The role of thrombin and fibrin generation in host defence is now re...

    Authors: Xavier Delabranche, Julie Helms and Ferhat Meziani

    Citation: Annals of Intensive Care 2017 7:117

    Published on:

  23. Content type: Research

    Impact of metformin exposure before ICU stay remains controversial. Metformin is thought to induce lactic acidosis and haemodynamic instability but may reduce ICU mortality. We evaluated its influence on outco...

    Authors: Sebastien Jochmans, Jean-Emmanuel Alphonsine, Jonathan Chelly, Ly Van Phach Vong, Oumar Sy, Nathalie Rolin, Olivier Ellrodt, Mehran Monchi and Christophe Vinsonneau

    Citation: Annals of Intensive Care 2017 7:116

    Published on:

  24. Content type: Review

    Beyond haemostasis, platelets have emerged as versatile effectors of the immune response. The contribution of platelets in inflammation, tissue integrity and defence against infections has considerably widened...

    Authors: Antoine Dewitte, Sébastien Lepreux, Julien Villeneuve, Claire Rigothier, Christian Combe, Alexandre Ouattara and Jean Ripoche

    Citation: Annals of Intensive Care 2017 7:115

    Published on:

    The Correction to this article has been published in Annals of Intensive Care 2018 8:32

  25. Content type: Research

    Serum procalcitonin (PCT) concentration is used to guide antibiotic decisions in choice, timing, and duration of anti-infection therapy to avoid antibiotic overuse. Thus, we performed a systematic review and m...

    Authors: Hui-Bin Huang, Jin-Min Peng, Li Weng, Chun-Yao Wang, Wei Jiang and Bin Du

    Citation: Annals of Intensive Care 2017 7:114

    Published on:

  26. Content type: Review

    Several studies suggest that alternatives to carbapenems, and particulary beta-lactam/beta-lactamase inhibitor combinations, can be used for therapy of extended-spectrum beta-lactamase-producing Enterobacteria...

    Authors: Benoit Pilmis, Vincent Jullien, Alexis Tabah, Jean-Ralph Zahar and Christian Brun-Buisson

    Citation: Annals of Intensive Care 2017 7:113

    Published on:

  27. Content type: Research

    An extended course of tetanus (up to 6 weeks) requiring ICU admission and protracted mechanical ventilation (MV) may have a significant impact on short- and long-term survival. The subject is noteworthy and d...

    Authors: Rafael Mahieu, Thomas Reydel, Adel Maamar, Jean-Marc Tadié, Angeline Jamet, Arnaud W. Thille, Nicolas Chudeau, Julien Huntzinger, Steven Grangé, Gaetan Beduneau, Anne Courte, Stephane Ehrmann, Jérémie Lemarié, Sébastien Gibot, Michael Darmon, Christophe Guitton…

    Citation: Annals of Intensive Care 2017 7:112

    Published on:

  28. Content type: Research

    Nosocomial infections occurring during extracorporeal membrane oxygenation (ECMO) support have already been reported, but few studied infections directly related to ECMO devices. This study aims to evaluate t...

    Authors: Guillemette Thomas, Sami Hraiech, Nadim Cassir, Samuel Lehingue, Romain Rambaud, Sandrine Wiramus, Christophe Guervilly, Fanny Klasen, Mélanie Adda, Stéphanie Dizier, Antoine Roch, Laurent Papazian and Jean-Marie Forel

    Citation: Annals of Intensive Care 2017 7:111

    Published on:

  29. Content type: Research

    No single anticoagulant has been proven effective for sepsis-associated disseminated intravascular coagulation (DIC). Thus, the concomitant use of antithrombin concentrate and recombinant thrombomodulin has be...

    Authors: Toshiaki Iba, Akiyoshi Hagiwara, Daizoh Saitoh, Hideaki Anan, Yutaka Ueki, Koichi Sato and Satoshi Gando

    Citation: Annals of Intensive Care 2017 7:110

    Published on:

  30. Content type: Research

    Continuous aspiration of subglottic secretions is effective in preventing ventilator-associated pneumonia, but it involves a risk of mucosal damage. The main objective of our study was to determine the inciden...

    Authors: Jordi Vallés, Susana Millán, Emili Díaz, Eva Castanyer, Xavier Gallardo, Ignacio Martín-Loeches, Marta Andreu, Mario Prenafeta, Paula Saludes, Jorge Lema, Montse Batlle, Néstor Bacelar and Antoni Artigas

    Citation: Annals of Intensive Care 2017 7:109

    Published on:

  31. Content type: Research

    We assessed the potential of risk stratification of ARDS patients using SpO2/FiO2 and positive end-expiratory pressure (PEEP) at ARDS onset and after 24 h.

    Authors: Luigi Pisani, Jan-Paul Roozeman, Fabienne D. Simonis, Antonio Giangregorio, Sophia M. van der Hoeven, Laura R. Schouten, Janneke Horn, Ary Serpa Neto, Emir Festic, Arjen M. Dondorp, Salvatore Grasso, Lieuwe D. Bos and Marcus J. Schultz

    Citation: Annals of Intensive Care 2017 7:108

    Published on:

  32. Content type: Research

    Anemia is prevalent at pediatric intensive care unit (PICU) admission and incident during PICU stay, but little is known about anemia at PICU discharge . Anemia after critical illness is an important issue bec...

    Authors: Pierre Demaret, Oliver Karam, Marisa Tucci, Jacques Lacroix, Hélène Behal, Alain Duhamel, Frédéric Lebrun, André Mulder and Stéphane Leteurtre

    Citation: Annals of Intensive Care 2017 7:107

    Published on:

  33. Content type: Research

    Ventilator-associated pneumonia (VAP) is a care-related event that could be promoted by immune suppression caused by critical diseases, malignancies and cancer treatments. Low dose of hydrocortisone was propos...

    Authors: David Lagier, Laura Platon, Jérome Lambert, Laurent Chow-Chine, Antoine Sannini, Magali Bisbal, Jean-Paul Brun, Karim Asehnoune, Marc Leone, Marion Faucher and Djamel Mokart

    Citation: Annals of Intensive Care 2017 7:106

    Published on:

  34. Content type: Research

    Sepsis-related acute kidney injury (AKI) accounts for major morbidity and mortality among the critically ill. Heparin-binding protein (HBP) is a promising biomarker in predicting development and prognosis of s...

    Authors: Jonas Tverring, Suvi T. Vaara, Jane Fisher, Meri Poukkanen, Ville Pettilä and Adam Linder

    Citation: Annals of Intensive Care 2017 7:105

    Published on:

  35. Content type: Research

    Quantitative and qualitative changes of skeletal muscle are typical and early findings in trauma patients, being possibly associated with functional impairment. Early assessment of muscle changes—as evaluated ...

    Authors: Maria Giuseppina Annetta, Mauro Pittiruti, Davide Silvestri, Domenico Luca Grieco, Alessio Maccaglia, Michele Fabio La Torre, Nicola Magarelli, Giovanna Mercurio, Anselmo Caricato and Massimo Antonelli

    Citation: Annals of Intensive Care 2017 7:104

    Published on:

  36. Content type: Research

    Organ failure increases mortality in patients with liver cirrhosis. Data about resuscitated cardiac arrest patients with liver cirrhosis are missing. This study aims to assess aetiology, survival and functiona...

    Authors: Kevin Roedl, Christian Wallmüller, Andreas Drolz, Thomas Horvatits, Karoline Rutter, Alexander Spiel, Julia Ortbauer, Peter Stratil, Pia Hubner, Christoph Weiser, Jasmin Katrin Motaabbed, Dominik Jarczak, Harald Herkner, Fritz Sterz and Valentin Fuhrmann

    Citation: Annals of Intensive Care 2017 7:103

    Published on:

  37. Content type: Research

    Disruption of the endothelial glycocalyx contributes to acute lung injury in experimental sepsis but has not been well studied in humans. To study glycocalyx degradation in sepsis-induced ARDS, we measured pla...

    Authors: Laura S. Murphy, Nancy Wickersham, J. Brennan McNeil, Ciara M. Shaver, Addison K. May, Julie A. Bastarache and Lorraine B. Ware

    Citation: Annals of Intensive Care 2017 7:102

    Published on:

  38. Content type: Research

    Elevated lactate concentration has been associated with increased mortality after out-of-hospital cardiac arrest (CA). We investigated the variables associated with high blood lactate concentrations and explor...

    Authors: Antonio Maria Dell’Anna, Claudio Sandroni, Irene Lamanna, Ilaria Belloni, Katia Donadello, Jacques Creteur, Jean-Louis Vincent and Fabio Silvio Taccone

    Citation: Annals of Intensive Care 2017 7:101

    Published on:

  39. Content type: Research

    In pressure-controlled (PC) ventilation, tidal volume (V T) and transpulmonary pressure (P L ) result from the addition...

    Authors: Nuttapol Rittayamai, François Beloncle, Ewan C. Goligher, Lu Chen, Jordi Mancebo, Jean-Christophe M. Richard and Laurent Brochard

    Citation: Annals of Intensive Care 2017 7:100

    Published on:

  40. Content type: Research

    Acetaminophen (APAP)-induced acute liver failure (ALF) is associated with significant mortality due to intracranial hypertension (ICH), a result of cerebral edema (CE) and astrocyte swelling. Brain-type fatty ...

    Authors: Constantine J. Karvellas, Jaime L. Speiser, Mélanie Tremblay, William M. Lee and Christopher F. Rose

    Citation: Annals of Intensive Care 2017 7:99

    Published on:

  41. Content type: Research

    Interstitial pneumonia with autoimmune features (IPAF) identifies a recently recognized autoimmune syndrome characterized by interstitial lung disease and autoantibodies positivity, but absence of a specific c...

    Authors: Giacomo Grasselli, Beatrice Vergnano, Maria Rosa Pozzi, Vittoria Sala, Gabriele D’Andrea, Vittorio Scaravilli, Marco Mantero, Alberto Pesci and Antonio Pesenti

    Citation: Annals of Intensive Care 2017 7:98

    Published on:

  42. Content type: Research

    Venous thromboembolism (VTE) is one of the most common preventable causes of in-hospital death in trauma patients surviving their injuries. We assessed the prevalence, incidence and risk factors for deep venou...

    Authors: S. R. Hamada, C. Espina, T. Guedj, R. Buaron, A. Harrois, S. Figueiredo and J. Duranteau

    Citation: Annals of Intensive Care 2017 7:97

    Published on:

  43. Content type: Research

    Prognostic scores and models of illness severity are useful both clinically and for research. The aim of this study was to develop two prognostic models for the prediction of long-term (6 months) and 28-day m...

    Authors: Ascanio Tridente, Julian Bion, Gary H. Mills, Anthony C. Gordon, Geraldine. M. Clarke, Andrew Walden, Paula Hutton, Paul A. H. Holloway, Jean-Daniel Chiche, Frank Stuber, Christopher Garrard and Charles Hinds

    Citation: Annals of Intensive Care 2017 7:96

    Published on:

  44. Content type: Research

    Active mobilization is not possible in patients under deep sedation and unable to follow commands. In this scenario, passive therapy is an interesting alternative. However, in patients with septic shock, passi...

    Authors: Tuanny Teixeira Pinheiro, Flávio Geraldo Rezende de Freitas, Karla Tuanny Fiorese Coimbra, Vanessa Marques Ferreira Mendez, Heloísa Baccaro Rossetti, Paulo Vinicius Talma, Antônio Tonete Bafi and Flávia Ribeiro Machado

    Citation: Annals of Intensive Care 2017 7:95

    Published on:

  45. Content type: Research

    Echocardiographic myocardial dysfunction is reported commonly in sepsis and septic shock, but there are limited data on sepsis-related right ventricular dysfunction. This study sought to evaluate the associati...

    Authors: Saraschandra Vallabhajosyula, Mukesh Kumar, Govind Pandompatam, Ankit Sakhuja, Rahul Kashyap, Kianoush Kashani, Ognjen Gajic, Jeffrey B. Geske and Jacob C. Jentzer

    Citation: Annals of Intensive Care 2017 7:94

    Published on:

  46. Content type: Research

    Plasma concentrations of endocan, a proteoglycan preferentially expressed in the pulmonary vasculature, may represent a biomarker of lung (dys)function. We sought to determine whether the measurement of plasma...

    Authors: Diego Orbegozo, Lokmane Rahmania, Marian Irazabal, Manuel Mendoza, Filippo Annoni, Daniel De Backer, Jacques Creteur and Jean-Louis Vincent

    Citation: Annals of Intensive Care 2017 7:93

    Published on:

  47. Content type: Research

    To analyse the usefulness of the composite index of the tissue inhibitor of metalloproteinases-2 (TIMP-2) and insulin-like growth factor-binding protein 7 (IGFBP7) as urinary biomarkers for the early predictio...

    Authors: M. Cuartero, J. Ballús, J. Sabater, X. Pérez, N. Nin, J. Ordonez-Llanos and A. J. Betbesé

    Citation: Annals of Intensive Care 2017 7:92

    Published on:

  48. Content type: Research

    The soluble cluster of differentiation 14 (or presepsin) is a free fragment of glycoprotein expressed on monocytes and macrophages. Although many studies have been conducted recently, the diagnostic performan...

    Authors: Chin-Chieh Wu, Hao-Min Lan, Shih-Tsung Han, Chung-Hsien Chaou, Chun-Fu Yeh, Su-Hsun Liu, Chih-Huang Li, Gerald N. Blaney III, Zhen-Ying Liu and Kuan-Fu Chen

    Citation: Annals of Intensive Care 2017 7:91

    Published on:

Official journal of

Annual Journal Metrics